KR20240021906A - 발현 벡터, 박테리아 서열-무함유 벡터, 및 이를 제조하고 사용하는 방법 - Google Patents
발현 벡터, 박테리아 서열-무함유 벡터, 및 이를 제조하고 사용하는 방법 Download PDFInfo
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- KR20240021906A KR20240021906A KR1020247001300A KR20247001300A KR20240021906A KR 20240021906 A KR20240021906 A KR 20240021906A KR 1020247001300 A KR1020247001300 A KR 1020247001300A KR 20247001300 A KR20247001300 A KR 20247001300A KR 20240021906 A KR20240021906 A KR 20240021906A
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/90—Stable introduction of foreign DNA into chromosome
- C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/20—Type of nucleic acid involving clustered regularly interspaced short palindromic repeats [CRISPR]
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- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16111—Cytomegalovirus, e.g. human herpesvirus 5
- C12N2710/16141—Use of virus, viral particle or viral elements as a vector
- C12N2710/16143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16111—Cytomegalovirus, e.g. human herpesvirus 5
- C12N2710/16141—Use of virus, viral particle or viral elements as a vector
- C12N2710/16145—Special targeting system for viral vectors
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2800/00—Nucleic acids vectors
- C12N2800/30—Vector systems comprising sequences for excision in presence of a recombinase, e.g. loxP or FRT
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/15—Vector systems having a special element relevant for transcription chimeric enhancer/promoter combination
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/42—Vector systems having a special element relevant for transcription being an intron or intervening sequence for splicing and/or stability of RNA
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/46—Vector systems having a special element relevant for transcription elements influencing chromatin structure, e.g. scaffold/matrix attachment region, methylation free island
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/48—Vector systems having a special element relevant for transcription regulating transport or export of RNA, e.g. RRE, PRE, WPRE, CTE
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/50—Vector systems having a special element relevant for transcription regulating RNA stability, not being an intron, e.g. poly A signal
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Mycology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163211343P | 2021-06-16 | 2021-06-16 | |
| US63/211,343 | 2021-06-16 | ||
| US202263306015P | 2022-02-02 | 2022-02-02 | |
| US63/306,015 | 2022-02-02 | ||
| US202263331638P | 2022-04-15 | 2022-04-15 | |
| US63/331,638 | 2022-04-15 | ||
| PCT/IB2022/055620 WO2022264095A1 (en) | 2021-06-16 | 2022-06-16 | Expression vectors, bacterial sequence-free vectors, and methods of making and using the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20240021906A true KR20240021906A (ko) | 2024-02-19 |
Family
ID=84527300
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020247001300A Pending KR20240021906A (ko) | 2021-06-16 | 2022-06-16 | 발현 벡터, 박테리아 서열-무함유 벡터, 및 이를 제조하고 사용하는 방법 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20240229071A1 (https=) |
| EP (1) | EP4355883A4 (https=) |
| JP (1) | JP2024523343A (https=) |
| KR (1) | KR20240021906A (https=) |
| AU (1) | AU2022292197A1 (https=) |
| BR (1) | BR112023026176A2 (https=) |
| CA (1) | CA3222578A1 (https=) |
| MX (1) | MX2023014628A (https=) |
| WO (1) | WO2022264095A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024058155A1 (ja) * | 2022-09-12 | 2024-03-21 | 株式会社カネカ | 二本鎖環状dnaベクター、直鎖状共有結合閉鎖dnaの作製方法、並びにプロテロメラーゼ及びエンドヌクレアーゼを含む融合ポリペプチド |
| WO2025057672A1 (ja) * | 2023-09-12 | 2025-03-20 | 株式会社カネカ | 形質転換細胞及び直鎖状共有結合閉鎖dnaの作製方法 |
| WO2025175381A1 (en) * | 2024-02-22 | 2025-08-28 | Pegasus Biotech Incorporated | Plasmid and method for production of dna vaccines and dna products |
| WO2025250465A1 (en) * | 2024-05-28 | 2025-12-04 | Nanjing Probio Biotech Co., Ltd. | Vector composition and use thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9862954B2 (en) * | 2012-11-22 | 2018-01-09 | Mediphage Bioceuticals, Inc. | DNA vector production system |
-
2022
- 2022-06-16 WO PCT/IB2022/055620 patent/WO2022264095A1/en not_active Ceased
- 2022-06-16 KR KR1020247001300A patent/KR20240021906A/ko active Pending
- 2022-06-16 EP EP22824423.2A patent/EP4355883A4/en active Pending
- 2022-06-16 MX MX2023014628A patent/MX2023014628A/es unknown
- 2022-06-16 BR BR112023026176A patent/BR112023026176A2/pt unknown
- 2022-06-16 AU AU2022292197A patent/AU2022292197A1/en active Pending
- 2022-06-16 CA CA3222578A patent/CA3222578A1/en active Pending
- 2022-06-16 JP JP2023577551A patent/JP2024523343A/ja active Pending
-
2023
- 2023-12-15 US US18/541,459 patent/US20240229071A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2024523343A (ja) | 2024-06-28 |
| EP4355883A1 (en) | 2024-04-24 |
| WO2022264095A1 (en) | 2022-12-22 |
| AU2022292197A1 (en) | 2023-12-21 |
| MX2023014628A (es) | 2024-02-28 |
| BR112023026176A2 (pt) | 2024-03-05 |
| EP4355883A4 (en) | 2025-06-18 |
| CA3222578A1 (en) | 2022-12-22 |
| US20240229071A1 (en) | 2024-07-11 |
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St.27 status event code: A-1-1-Q10-Q12-nap-PG1501 |
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| A201 | Request for examination | ||
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St.27 status event code: A-2-3-E10-E13-lim-X000 |
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St.27 status event code: A-2-2-P10-P11-nap-X000 |
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| P13-X000 | Application amended |
St.27 status event code: A-2-2-P10-P13-nap-X000 |