KR20230128527A - 알데히드에 의한 니트릴히드라타아제의 반응성 향상 - Google Patents

알데히드에 의한 니트릴히드라타아제의 반응성 향상 Download PDF

Info

Publication number
KR20230128527A
KR20230128527A KR1020237026373A KR20237026373A KR20230128527A KR 20230128527 A KR20230128527 A KR 20230128527A KR 1020237026373 A KR1020237026373 A KR 1020237026373A KR 20237026373 A KR20237026373 A KR 20237026373A KR 20230128527 A KR20230128527 A KR 20230128527A
Authority
KR
South Korea
Prior art keywords
compound
nitrile
aldehyde
reaction
glu
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
KR1020237026373A
Other languages
English (en)
Korean (ko)
Inventor
다카후미 야마구치
노리후미 하기야
마코토 가노
가즈야 다카나시
Original Assignee
미쯔비시 케미컬 주식회사
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 미쯔비시 케미컬 주식회사 filed Critical 미쯔비시 케미컬 주식회사
Publication of KR20230128527A publication Critical patent/KR20230128527A/ko
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/01—Hydro-lyases (4.2.1)
    • C12Y402/01084—Nitrile hydratase (4.2.1.84)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Enzymes And Modification Thereof (AREA)
KR1020237026373A 2021-02-10 2022-02-07 알데히드에 의한 니트릴히드라타아제의 반응성 향상 Pending KR20230128527A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2021019409 2021-02-10
JPJP-P-2021-019409 2021-02-10
PCT/JP2022/004577 WO2022172880A1 (ja) 2021-02-10 2022-02-07 アルデヒドによるニトリルヒドラターゼの反応性向上

Publications (1)

Publication Number Publication Date
KR20230128527A true KR20230128527A (ko) 2023-09-05

Family

ID=82837863

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020237026373A Pending KR20230128527A (ko) 2021-02-10 2022-02-07 알데히드에 의한 니트릴히드라타아제의 반응성 향상

Country Status (7)

Country Link
US (1) US20240093251A1 (https=)
EP (1) EP4279600A4 (https=)
JP (2) JP7605214B2 (https=)
KR (1) KR20230128527A (https=)
CN (1) CN116888269A (https=)
AU (1) AU2022219778A1 (https=)
WO (1) WO2022172880A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4279600A4 (en) * 2021-02-10 2025-06-11 Mitsubishi Chemical Corporation Improved nitrile hydratase reactivity using aldehyde

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11123098A (ja) 1997-10-23 1999-05-11 Mitsubishi Rayon Co Ltd アミド化合物の製造方法
JP2001288156A (ja) 2000-04-04 2001-10-16 Mitsubishi Rayon Co Ltd ニトリル化合物の精製方法
JP2005295815A (ja) 2004-04-07 2005-10-27 Mitsui Chemicals Inc ニトリルヒドラターゼの安定化または活性化方法
KR20070043466A (ko) 2005-10-21 2007-04-25 엘지전자 주식회사 엠피쓰리 플레이어를 지원하는 휴대용 컴퓨터의 제어장치및 방법
JP2010172295A (ja) 2009-01-30 2010-08-12 Mitsubishi Rayon Co Ltd 改良型ニトリルヒドラターゼ及びその製造方法

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5617918A (en) 1979-07-23 1981-02-20 Chisso Corp Manufacture of dichlorosilane
AU627648B2 (en) 1990-02-28 1992-08-27 Teruhiko Beppu Dna fragment encoding a polypeptide having nitrile hydratase activity, a transformant containing the gene and a process for the production of amides using the transformant
JP3076631B2 (ja) 1991-07-12 2000-08-14 ダイセル化学工業株式会社 アミド化合物の製造方法および新規な微生物
JPH0530982A (ja) 1991-08-05 1993-02-09 Mitsubishi Kasei Corp アミド類の製造法
JPH05161495A (ja) 1991-12-17 1993-06-29 Mitsubishi Kasei Corp アミド類の製造法
JPH05103681A (ja) 1991-10-14 1993-04-27 Mitsubishi Kasei Corp アミド類の製造法
JPH0530983A (ja) 1991-08-05 1993-02-09 Mitsubishi Kasei Corp アミド類の製造法
JPH05236975A (ja) 1992-02-28 1993-09-17 Mitsubishi Kasei Corp アミド類の製造法
JPH05236976A (ja) 1992-02-28 1993-09-17 Mitsubishi Kasei Corp アミド類の製造法
JPH0530984A (ja) 1991-08-05 1993-02-09 Mitsubishi Kasei Corp アミド類の製造法
JPH05236977A (ja) 1991-09-12 1993-09-17 Mitsubishi Kasei Corp アミド類の製造法
JP3409353B2 (ja) 1992-04-30 2003-05-26 住友化学工業株式会社 アミド化合物の製造方法および使用される微生物
JPH0655148A (ja) 1992-08-06 1994-03-01 Hitachi Ltd ガラス基板洗浄装置
JPH0725494A (ja) 1993-07-06 1995-01-27 Tec Corp 給紙ローラ機構
JPH0856684A (ja) 1994-08-16 1996-03-05 Mitsui Toatsu Chem Inc 微生物によるアミド化合物の製造法
JP3531997B2 (ja) 1995-03-29 2004-05-31 三井化学株式会社 形質転換体を用いたアミド化合物の製造法
JP3380133B2 (ja) 1996-02-14 2003-02-24 三井化学株式会社 新規なニトリルヒドラターゼ
US5863750A (en) * 1996-12-18 1999-01-26 Cytec Tech Corp Methods for the detoxification of nitrile and/or amide compounds
JP4672914B2 (ja) 2001-06-15 2011-04-20 ダイセル化学工業株式会社 アミド化合物の製造方法
EP1689861B1 (en) 2003-12-02 2011-11-09 Ciba Specialty Chemicals Water Treatments Limited Strain of rhodococcus rhodochrous ncimb 41164 and its use as producer of nitrile hydratase
CN103146670B (zh) 2004-05-26 2014-11-26 Dia-Nitrix株式会社 改良型腈水合酶
GB0416101D0 (en) * 2004-07-19 2004-08-18 Ciba Spec Chem Water Treat Ltd Process for preparing monomers and polymers thereof
JP4916685B2 (ja) 2005-08-05 2012-04-18 三菱レイヨン株式会社 改良型ニトリルヒドラターゼ
JP4916709B2 (ja) 2005-11-24 2012-04-18 三菱レイヨン株式会社 改良型ニトリルヒドラターゼ
JP5030579B2 (ja) 2006-12-26 2012-09-19 三菱レイヨン株式会社 ロドコッカス属細菌用発現ベクター
JP5069032B2 (ja) 2007-04-04 2012-11-07 ダイヤニトリックス株式会社 改良型ニトリルヒドラターゼ
JP2010022334A (ja) 2008-07-24 2010-02-04 Mitsubishi Rayon Co Ltd 立体選択性を有するニトリルヒドラターゼ遺伝子
KR101835160B1 (ko) 2010-02-22 2018-03-07 미쯔비시 케미컬 주식회사 안정된 아크릴아마이드 수용액
CN103649312B (zh) 2011-05-31 2017-03-22 三菱丽阳株式会社 改良型腈水合酶
EP2811021B1 (en) 2011-06-07 2016-11-02 Mitsubishi Rayon Co., Ltd. Improved nitrile hydratase
RU2689606C2 (ru) 2014-06-06 2019-05-28 Мицубиси Кемикал Корпорейшн Улучшенная нитрилгидратаза
CN106795227B (zh) 2014-12-17 2018-10-02 三菱化学株式会社 丙烯酰胺水溶液及丙烯酰胺系聚合物的制造方法
JP2017184686A (ja) 2016-04-08 2017-10-12 三菱ケミカル株式会社 グルタルアルデヒド含有酵素組成物
JP7243506B2 (ja) 2019-07-18 2023-03-22 株式会社デンソー モータ
EP4279600A4 (en) * 2021-02-10 2025-06-11 Mitsubishi Chemical Corporation Improved nitrile hydratase reactivity using aldehyde

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11123098A (ja) 1997-10-23 1999-05-11 Mitsubishi Rayon Co Ltd アミド化合物の製造方法
JP2001288156A (ja) 2000-04-04 2001-10-16 Mitsubishi Rayon Co Ltd ニトリル化合物の精製方法
JP2005295815A (ja) 2004-04-07 2005-10-27 Mitsui Chemicals Inc ニトリルヒドラターゼの安定化または活性化方法
KR20070043466A (ko) 2005-10-21 2007-04-25 엘지전자 주식회사 엠피쓰리 플레이어를 지원하는 휴대용 컴퓨터의 제어장치및 방법
JP2010172295A (ja) 2009-01-30 2010-08-12 Mitsubishi Rayon Co Ltd 改良型ニトリルヒドラターゼ及びその製造方法

Also Published As

Publication number Publication date
JP2024178359A (ja) 2024-12-24
US20240093251A1 (en) 2024-03-21
EP4279600A1 (en) 2023-11-22
JP7605214B2 (ja) 2024-12-24
EP4279600A4 (en) 2025-06-11
CN116888269A (zh) 2023-10-13
AU2022219778A9 (en) 2024-09-12
AU2022219778A1 (en) 2023-06-22
WO2022172880A1 (ja) 2022-08-18
JPWO2022172880A1 (https=) 2022-08-18

Similar Documents

Publication Publication Date Title
Gabor et al. Construction, characterization, and use of small‐insert gene banks of DNA isolated from soil and enrichment cultures for the recovery of novel amidases
JP4922757B2 (ja) 改良型ニトリルヒドラターゼ
JP3809192B2 (ja) 酵素類、それらの調製及びアクリル酸アンモニウムの製造へのそれらの使用
RU2385876C2 (ru) Устойчивые к цианидам нитрилгидратазы
KR100547080B1 (ko) 미생물 촉매를 이용한 아미드 화합물의 제조 방법
JP2024178359A (ja) アルデヒドによるニトリルヒドラターゼの反応性向上
US9382560B2 (en) Method for producing amide compound
JP2008228628A (ja) ニトリルヒドラターゼの製造方法
RU2827406C2 (ru) Повышение реакционной способности нитрилгидратазы с помощью альдегида
JP5226509B2 (ja) 改良型ハロヒドリンエポキシダーゼ
WO2014080687A1 (ja) １，４－ブタンジオールの製造方法及び微生物
WO2011148867A1 (ja) アミド化合物の製造方法
JP4785120B2 (ja) ハロヒドリンエポキシダーゼ活性を有するロドコッカス属細菌の形質転換体
US5153123A (en) Method for producing l-threonine, and plasmid and microorganism employed in the same
CN121379995B (zh) 一组赭曲霉毒素a降解酶突变体及其应用
JP4709186B2 (ja) 微生物触媒を用いたアミド化合物の製造方法
JP2010022314A (ja) カルボン酸の製造方法
CN120917145A (zh) 酰胺化合物的制造方法
JP3437879B2 (ja) 細菌の培養法
Bhalla et al. Nitrile metabolizing yeasts
EP4490284A2 (en) Variant nitrile hydratases, microbia which express same, and use in amide synthesis
JP2005245242A (ja) ヒドロキシニトリルリアーゼの製造方法
HU216880B (hu) Eljárás L(-)-almasav előállítására fumaráz-C-enzimet túltermelő rekombináns baktériumok alkalmazásával
JP2001120290A (ja) 微生物によるカルボン酸類の製法
AU2015203203A1 (en) Improved nitrile hydratase

Legal Events

Date Code Title Description
A201 Request for examination
E13-X000 Pre-grant limitation requested

St.27 status event code: A-2-3-E10-E13-lim-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PA0105 International application

St.27 status event code: A-0-1-A10-A15-nap-PA0105

PA0201 Request for examination

St.27 status event code: A-1-2-D10-D11-exm-PA0201

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

D21 Rejection of application intended

Free format text: ST27 STATUS EVENT CODE: A-1-2-D10-D21-EXM-PE0902 (AS PROVIDED BY THE NATIONAL OFFICE)

PE0902 Notice of grounds for rejection

St.27 status event code: A-1-2-D10-D21-exm-PE0902

P11 Amendment of application requested

Free format text: ST27 STATUS EVENT CODE: A-2-2-P10-P11-NAP-X000 (AS PROVIDED BY THE NATIONAL OFFICE)

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13 Application amended

Free format text: ST27 STATUS EVENT CODE: A-2-2-P10-P13-NAP-X000 (AS PROVIDED BY THE NATIONAL OFFICE)

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000