KR20230098421A - Composition for weight loss and manufacturing method thereof - Google Patents

Abstract

Disclosed in the present invention is a composition for weight loss, comprising Zanthoxylum piperitum, Citrus unshiu, Pueraria lobata var. thomsonii, Perilla frutescens var. crispa, Cinnamomum verum, Pericarpium citri, and Foeniculum vulgare. According to the present invention, by containing natural herbal medicines with excellent weight loss efficacy, such as Zanthoxylum piperitum, Citrus unshiu, etc., in optimal proportions, it is possible to effectively reduce body weight without any side effects on the human body and prevent various diseases caused by overweight or obesity.

Description

Composition for weight loss and manufacturing method thereof

The present invention relates to a composition for weight loss and a method for manufacturing the same, and more particularly, to a composition for weight loss containing natural oriental medicinal herbs excellent in weight loss efficacy, such as Japanese pepper and dermis, in an optimal ratio, and a method for manufacturing the same. .

The origin of the representative adult diseases of modern people is derived from obesity. Obesity refers to a state in which the amount of stored adipose tissue is abnormally increased. In general, obesity refers to when fat accounts for 30% or more of body weight.

The causes of obesity include genetic factors, environmental factors such as irregular eating habits, lack of exercise, or excessive consumption of fast food, psychological factors such as depression and excessive stress, and hormonal factors due to changes in thyroid or adrenal cortical hormones. .

Obesity is caused by the accumulation of unnecessary fat in the body when the amount of calories consumed exceeds the amount consumed. Therefore, in order to solve obesity, reduce the accumulation of fat in the body or use the accumulated fat as an energy source to consume it. it has to be done

On the other hand, when fat accumulates in the body, the smooth metabolism of the body is disturbed and the function of the intestines deteriorates, for example, diabetes, high blood pressure, arteriosclerosis, hyperlipidemia, cardiovascular disease, fatty liver, etc. be the root cause of

After a significant amount of fat is accumulated in the body, it is difficult to lose weight even if diet and exercise are combined. This is because fat is more easily stored in the body.

In the case of excessive diet, excessive exercise, and reckless drug abuse in a state where the body's metabolic function is significantly off, a slight weight loss can be expected, but it can cause side effects such as extreme hunger, helplessness, and dizziness. do. In addition, when weight is reduced simply by reducing the amount of food eaten, the yo-yo phenomenon causes the adverse effect of gaining more weight than before.

Therefore, there is a need for a composition and method for weight loss that is safe, scientific, nutritionally physiologically free, and has no yo-yo phenomenon.

In order to recognize the above phenomenon and solve it, many methods have been proposed in the past. For example, in Korean Patent Publication No. 10-2003-0005086 (Patent Document 0001), a diet composition containing raw food and dietary fiber is called As a result, a diet composition containing raw food composed of freeze-dried powders of grains, vegetables, seaweed, dietary fiber, and functional herb extracts is disclosed, and Korean Patent Registration No. 10-0645385 (Patent Document 0002) inhibits obesity Under the name of Composition for Use, it discloses a composition for suppressing obesity containing melissa leaf extract, ginseng mugwort extract, and mulberry leaf extract as active ingredients. Under the name of a herbal medicine extract composition having, a composition for the prevention and treatment of obesity containing extracts of pine needles, Sangyeop, birch leaf, neck fruit, and Lonicera Japonica Thumb as active ingredients is disclosed.

However, the inventions disclosed in the above patent documents provide a functional composition that provides a diet effect by simply mixing natural ingredients having specific functionality, and it is suggested that each ingredient can exert a synergistic effect on obesity improvement. In addition, it has not been disclosed how to effectively absorb into the human body in order to improve functionality and to suppress or eliminate side effects caused by ingestion.

Therefore, the inventors of the present invention recognize the problems to be solved in the prior art, and synergistically improve obesity without side effects due to intake through an appropriate combination of herbal medicines known to have an effect of improving obesity through weight loss. The present invention was completed by intensive research on a method capable of exerting an effect and providing a way to effectively absorb into the human body.

Republic of Korea Patent Publication No. 10-2003-0005086 Republic of Korea Patent Registration No. 10-0645385 Republic of Korea Patent Registration No. 10-0813187

The present invention was devised in view of the above points, and by including natural herbal medicines excellent in weight loss efficacy such as Japanese pepper and dermis in an optimal ratio, it effectively reduces body weight without any side effects on the human body, thereby preventing overweight or obesity. It is an object of the present invention to provide a composition for weight loss that can prevent various diseases caused by and a manufacturing method thereof.

In addition, the present invention may be aimed at achieving other objects that can be easily derived by a person skilled in the art from the general description of the present specification and these objects in addition to the clear objects described above.

In order to achieve the above object, the present invention provides a composition for weight loss, including Chinese pepper, dermis, root root, leaflet, cinnamon, green skin and fennel.

Here, the Japanese pepper is 1 to 30 parts by weight, the dermis is 1 to 30 parts by weight, the root is 1 to 30 parts by weight, the lobules are 1 to 30 parts by weight, the cinnamon is 1 to 30 parts by weight, the green skin is 1 to 30 parts by weight and the fennel may include 1 to 30 parts by weight.

Here, the pepper, dermis, root, leaflet, cinnamon, green skin and fennel may be included in the same weight.

Here, the weight loss composition may be a hot water extract.

Here, the composition for weight loss may be a powder or pill obtained by drying a hot water extract.

Here, the weight loss composition may further include any one of a carrier, an excipient, or a diluent.

On the other hand, the present invention includes the steps of extracting hot water by combining sancho, dermis, root of root, lobules, cinnamon, cheongpi and fennel; Concentrating the hot water extract; It further provides a method for producing a composition for weight loss comprising; and freeze-drying the concentrated extract.

Here, the hot water extraction may be performed for 1 to 5 hours at a temperature range of 80 to 120 °C.

Here, the concentrating step may be performed at a temperature range of 40 to 80 °C.

Here, the method for preparing the composition for weight loss may further include mixing any one of a carrier, an excipient, or a diluent after the step of concentrating the hot water extract.

The disclosed technology may have the following effects. However, it does not mean that a specific embodiment must include all of the following effects or only the following effects, so it should not be understood that the scope of rights of the disclosed technology is limited thereby.

The composition for weight loss and its manufacturing method of the present invention contain natural oriental medicines excellent in weight loss efficacy, such as Japanese pepper and dermis, in an optimal ratio, thereby effectively reducing body weight without any side effects on the human body, resulting in overweight or obesity. It has the effect of preventing various diseases.

Terms used in this application are only used to describe specific examples. Therefore, for example, expressions in the singular number include plural expressions unless the context clearly requires them to be singular. In addition, the terms "include" or "have" used in this application are used to clearly indicate that the features, steps, functions, components, or combinations thereof described in the specification exist, but other features It should be noted that it is not intended to be used to preliminarily exclude the presence of any steps, functions, components, or combinations thereof.

Meanwhile, unless otherwise defined, all terms used in this specification should be regarded as having the same meaning as commonly understood by a person of ordinary skill in the art to which the present invention belongs. Accordingly, certain terms should not be interpreted in an overly idealistic or formal sense unless clearly defined herein.

<Composition for weight loss of the present invention>

As a result of research in order to solve the above-mentioned problems, the inventors of the present invention came up with the following invention. The present specification discloses a composition for weight loss comprising sancho, dermis, root, lobules, cinnamon, green bark and fennel.

The Japanese pepper of the present invention is a medicinal material made by removing seeds as much as possible as the pericarp of the Rutaceae family (Zanthoxylum 　piperitum 　De 　Candolle) or the same plant. Sancho has a peculiar smell, the taste is spicy, and the nature is warm. Sancho has the effect of decomposing fat as it promotes fat metabolism, and can be used as a remedy for indigestion, eating, gastric sewage, vomiting, relief, toothache, dysentery, diarrhea, and roundworm remedies. Furthermore, the pharmacological action of Japanese pepper has been reported to have local anesthetic action, intestinal peristaltic action, antibacterial action, anti-inflammatory action, antioxidant action, and antimalarial action.

The dermis of the present invention refers to the mature rind of Citrus Unshiu Markovich or a related plant of the same genus. The dermis relieves the clogged qi and strengthens the function of the spleen, treating symptoms such as abdominal pain, belching, vomiting, nausea, indigestion, flatulence, drowsiness, and weak stool, removing seawater and phlegm, and has a diuretic effect. . It is a medicine whose medicinal effect increases with age along with recitative, mahuang, dermis, ohsuyu, banha, and jisil. The pharmacological action of the dermis has been reported that essential oils stimulate digestion, promote digestion, expectorant, anti-ulcer, anti-gastric juice secretion, cardiac heart, increase blood pressure, anti-allergy, promote bile secretion, inhibit uterine smooth muscle, and have antibacterial effects. In addition, the dermis is very low in calories, and if you consume it steadily, you can see the diet effect. Furthermore, the hesperidin component of the dermis is a typical tangerine peel component that inhibits fat absorption and promotes fat decomposition.

The root of the present invention refers to the dried root of a leguminous vine plant, arrowroot (Pueraria montana var. lobata: Pueraria lobata) or the root after removing the perianth and drying. The taste is sweet but very strong, and the energy is flat, so it is neither hot nor cold. As a mechanism that lowers heat while relaxing muscles, it treats colds, high fevers, headaches, muscle pains, and stiffness in the back of the neck. It is also used to raise yang qi and stop diarrhea. It is also used to replenish body fluids, quench thirst, and relieve alcohol poisoning. In addition, it is used for dysentery, high blood pressure, heart-related diseases, diabetes, and cancer. The calf muscle can effectively control stomach heat to control appetite, and the perspiration of the calf muscle can play a role in burning body fat. In addition, kudzu root is often used for the treatment of cardiovascular diseases such as high blood pressure, and an important component in cardiovascular action is 　puerarin of kudzu root. Furthermore, puerarin is known for its anti-diabetic activity, and the puerarin component of puerarin appears to be important in this action as well. can

The leaflet of the present invention is a medicinal material made from the leaves of Perilla frutescens var. acuta KUDO., an annual herbaceous plant belonging to the Lamiaceae family. It is used for symptoms that cause In particular, it is an essential drug for symptoms of a cold with digestive disorders. In addition, the lobules can activate the movement of the qi to prevent stagnation of the qi, and decompose body fat through sweating to lighten the body. Furthermore, when flatulence is called due to a food disorder and digestive power is reduced, complaining of cramps, gas is discharged to the outside and becomes comfortable. It is highly effective for symptoms of vomiting and twisting of the limbs due to vomiting, which often occurs in summer, and is used for indigestion caused by eating cold food or having a full stomach. In addition, it is widely used for symptoms such as shortness of breath due to full stomach during pregnancy and difficulty lying down.

Cinnamon of the present invention is a medicinal material made from the bark of the evergreen tree (Cinnamomum japonicum SIEB.), an evergreen tree belonging to the Lauraceae family. As it is active, there is an effect of decomposing body fat. Cinnamon tastes spicy and sweet, its weakness is heat, and its efficacy activates the function of the non-gastrointestinal tract, so it is widely used for digestive disorders due to cold digestive organs or abdominal pain and diarrhea caused by cold stomach. In addition, it causes a rapid response to vomiting caused by a full stomach. In addition, it stops quadriplegia and pain caused by customs, and is widely applied to painful neuralgia and joint diseases as the waist or knee is cold and cold. Furthermore, bleeding continues after childbirth or improves the symptoms of old dysentery and bleeding during stool. In addition, it is highly effective for symptoms of decreased kidney function and is also used for diseases in which cystitis often occurs due to a cold lower abdomen.

The green peel of the present invention refers to the unripe rind of Citrus Unshiu Markovich or a related plant of the same genus. Cheongpi has a refreshing sense of direction, the taste is bitter, a little spicy, and the nature is a little warm. Since the green skin acts on the liver, it is used for pain in the chest, flanks, stomach, hepatitis, gastritis, mastitis, and breast cancer. It is used for stress, indigestion from eating food, lumps in the chest, and ailments, and is also applied to liver cirrhosis and splenomegaly. It has been reported that essential oils stimulate digestion, promote digestion, expectorant, anti-ulcer, anti-gastric secretion, cardiotonia, increase blood pressure, anti-allergy, promote bile secretion, inhibit uterine smooth muscle, and have antibacterial effects. More specifically, green skin can show the effect of weight loss by promoting digestion and activating energy metabolism.

Fennel of the present invention means dried mature fruits of fennel (Foeniculum vulgare Miller), a perennial herb belonging to the genus Foeniculum of Apiaceae (or Umbelliferae / Apiaceae). Fennel has effects on the gastrointestinal system, liver function, analgesic action, anti-inflammatory activity, anti-allergic activity, anti-anxiety activity, anti-stress activity, memory-enhancing properties, anti-hirsutism activity, female hormone-like activity, and galactogenic activity. , expectorant activity, diuretic activity, action on the cardiovascular system, anti-thrombotic activity, anti-mutagenic activity, antipyretic activity, lipid-lowering activity, hypoglycemic activity, anticonvulsant activity, and apoptosis activity have been reported. That is, as mentioned in the lipid-lowering action, fennel has the effect of promoting lipolysis by activating energy metabolism.

As described above, the composition for weight loss according to the present invention contains Chinese pepper, dermis, root root, lobules, cinnamon, green skin and fennel, so it can exert an excellent weight loss effect through appetite control, satiety enhancement, body fat decomposition effect, etc. . Here, if any one of the pepper, dermis, root, lobules, cinnamon, green rind, and fennel of the present invention is not included, it is difficult to exert an excellent weight loss effect or concerns about preventing or minimizing side effects caused by any one component there is

The composition for weight loss of the present invention includes 1 to 30 parts by weight of the Japanese pepper, 1 to 30 parts by weight of the dermis, 1 to 30 parts by weight of the root root, 1 to 30 parts by weight of the lobules, 1 to 30 parts by weight of the cinnamon, and 1 to 30 parts by weight of the green bark. It is preferable to include 1 to 30 parts by weight and 1 to 30 parts by weight of the fennel, but is not limited thereto.

However, the range of parts by weight of each component constituting the composition for weight loss of the present invention is limited based on the effect of each component and the possibility of side effects, and the upper limit of the range of parts by weight considers side effects and the content of other components as a whole. It was determined and the lower limit of the range of parts by weight is limited to this numerical range because there is a problem that the effect of the component is less than that.

In addition, in the composition for weight loss of the present invention, it is preferable to mix the peppermint, dermis, root root, lobules, cinnamon, green peel, and fennel in the same weight ratio, that is, in a weight ratio of 1:1:1:1:1:1:1. However, it is not limited thereto. When the content of these seven components satisfies the preferred range of the present invention, it is possible to minimize side effects caused by oriental medicine while exhibiting a more increased effect in weight loss.

In addition to the above-mentioned ingredients, in consideration of the patient's constitution, Gojija, Tosaja, Bokbunja, Chajeonja, Schisandra, Sukjihwang, Cheonmundong, Maekmundong, Sanyak, Mansam, Baekchul, Baekbokryeong, Licorice, Ussul, Duchung, Cornus milk, Wonji, Seokchangpo, It may further include any one or more of herbal medicines such as mokhyang, sewage, astragalus, angelica, and jigolpi. At this time, the blending ratio of each component is preferably blended at the same weight ratio, but is not limited thereto.

Gojija is a deciduous tree, broad leaf, and shrub of Solanaceae, and the fruit of Goji tree is called Gojija and grows wild throughout Korea. In oriental medicine, the leaves are called gojiyeop, the fruit is gojija, and the root is called jigolpi, and it contains amino acids and vitamins, so it is used for energy loss, conjunctivitis, fatigue recovery, and dizziness. Goji berry contains vitamins, rutin, betaine, amino acids, etc., so it is highly effective as a tonic and is effective in preventing arteriosclerosis and high blood pressure.

Schisandra chinensis contains various types of pharmacologically active substances, so it is excellent in asthma treatment, brightens the eyes and warms the intestines. Schizandra chinensis contains ingredients such as shizandrin, gomisin, citral, malic acid, and citric acid, so it strengthens the heart, lowers blood pressure, and enhances immunity, so it is used as a tonic. It strengthens lung function and has antitussive and expectorant effects, helping to treat cough and thirst.

Baekbokryeong supplements the spleen and stomach, normalizes digestion, and reduces edema due to its water distillation function. It also reduces stress, relieves nervousness, and helps you sleep.

Macmundong is effective in treating diseases of the respiratory system such as dry cough, hematemesis, and hemoptysis. In addition, it has the function of preventing and increasing the damage of the essence in the body, helping to prevent constipation that can occur during diet.

Baekchul is effective in preventing chronic indigestion, enteritis, and diarrhea because it has stomach and digestive functions. Because it has a diuretic effect, it can be used in cases of edema caused by nephritis or edema in pregnant women.

Licorice harmonizes the toxicity of all medicines so that the medicinal effects appear well, controls the heat and morale of the books, improves the communication of all blood vessels, and strengthens muscles and bones. Pharmacological action is effective for detoxification, hepatitis, hives, dermatitis, and eczema. It has antitussive, expectorant, muscle relaxation, diuretic and anti-inflammatory properties, and suppresses peptic ulcer.

Useul enhances the contraction of the uterus, has a weak diuretic effect, and dilates blood vessels to temporarily lower blood pressure. Its medicinal properties are ordinary, and its taste is sour and bitter. The effect induces the woman's physiology to normal and facilitates diuresis and bowel movement.

Cornus officinalis is used as a medicine for headache, tinnitus, seawater disease, fever, hypermenorrhea, etc., and is also used for folk remedies such as night sweats and enuresis. Tea or alcohol is also good for longevity, and it has effects such as relieving cold and boeum.

Angelica pharmacologically promotes blood flow in the coronary arteries and stimulates red blood cell production. It has a blood-replenishing effect that generates blood when there is a lack of blood, and a blood-reducing effect that circulates blood smoothly, and has a strong blood pressure lowering effect. In addition, it helps to prevent constipation that can occur while dieting by promoting bowel movements.

The composition for weight loss of the present invention is preferably any one of an extract obtained by extraction treatment, a diluted or concentrated solution of the extract, a dried product obtained by drying the extract, a pill, a powder, or an adjusted or purified product thereof, but is not limited thereto. no.

The composition for weight loss of the present invention may be a hot water extract or a dried powder or pill of the hot water extract.

The composition for weight loss of the present invention may further include any one of a carrier, excipient, or diluent commonly used in the preparation of the composition.

The composition for weight loss of the present invention may be provided in the form of a plant composition, a health food composition, a health functional food composition, a health supplement composition, or a quasi-drug composition. Here, citric acid, high fructose corn syrup, sugar, glucose, acetic acid, malic acid, fruit juice, or other herbal extracts may be added to the composition for weight loss. As used in the present invention, the term "health food" means a food having an active health maintenance or promotion effect compared to general food, and "health supplement food" means food for health supplement purposes. In addition, the term "health functional food" used in the present invention is the same term as food for special health use, and is a medical and high-medical food processed to efficiently display bioregulatory functions in addition to nutritional supply. means As a specific example of the health functional food of the present invention, there are processed foods having improved storage stability while modifying the characteristics of agricultural products, livestock products, or marine products using the composition for weight loss of the present invention. In some cases, terms such as health food, health functional food, and health supplement food may be used interchangeably.

The food composition of the present invention can be used as a food or beverage additive, and the composition for weight loss of the present invention can be added as it is or used together with other foods or food ingredients, and can be appropriately used according to a conventional method. At this time, the mixing amount of the composition for weight loss of the present invention may be determined by appropriately adjusting according to the purpose of use (prevention, health, or therapeutic treatment). When the composition for weight loss of the present invention is formulated into a beverage, liquid components added in addition to the composition for weight loss are not limited, but, like conventional beverages, various flavoring agents or natural carbohydrates may be included as additional components. .

The quasi-drug composition of the present invention refers to an article that exhibits effects of treatment, alleviation, treatment, or prevention of diseases, but has a lesser effect on the human body than pharmaceuticals. Excluding items used for pharmaceutical purposes under the Pharmaceutical Affairs Act, including items according to the classification standards separately set by the Ministry of Health and Welfare. Specifically, it may be an external skin preparation or personal care product such as a diet patch, but is not limited thereto. When the composition for weight loss of the present invention is added to a quasi-drug composition, the composition may be added as it is or used together with other quasi-drug ingredients, and may be appropriately used according to a conventional method. The mixing amount of the active ingredient can be suitably determined depending on the purpose of use.

The composition for weight loss of the present invention is harmless to the human body by using natural herbal medicines, and has the advantage that it can be safely used even when used for a long period of time because there is little toxicity and side effects.

<Method for preparing composition for weight loss of the present invention>

On the other hand, the present specification includes the steps of extracting hot water by combining sancho, dermis, root, lobules, cinnamon, cheongpi and fennel; Concentrating the hot water extract; Further discloses a method for preparing a composition for weight loss comprising; and freeze-drying the concentrated extract.

In the preparation method of the composition for weight loss of the present invention, the mixing ratio of each component is 1 to 30 parts by weight of Japanese pepper, 1 to 30 parts by weight of the dermis, 1 to 30 parts by weight of the root of the root, 1 to 30 parts by weight of the lobules, and 1 part by weight of cinnamon. to 30 parts by weight, preferably containing 1 to 30 parts by weight of the green skin and 1 to 30 parts by weight of the dill, but is not limited thereto.

However, in the manufacturing method of the composition for weight loss of the present invention, the range of parts by weight of each component is limited based on the effect and possibility of side effects of each component, and the upper limit of the range of parts by weight considers side effects and the content of other components as a whole. It was determined and the lower limit of the range of parts by weight is limited to this numerical range because there is a problem that the effect of the component is less than that.

In addition, in the preparation method of the composition for weight loss of the present invention, the pepper, dermis, root root, leaflet, cinnamon, green peel, and fennel are mixed in the same weight ratio, that is, in a weight ratio of 1:1:1:1:1:1:1 It is preferable to do it, but it is not limited thereto. When the content of these seven components satisfies the preferred range of the present invention, it is possible to minimize side effects caused by oriental medicine while exhibiting a more increased effect in weight loss.

In addition to the above-mentioned ingredients, in consideration of the patient's constitution, Gojija, Tosaja, Bokbunja, Chajeonja, Schisandra, Sukjihwang, Cheonmundong, Maekmundong, Sanyak, Mansam, Baekchul, Baekbokryeong, Licorice, Ussul, Duchung, Cornus milk, Wonji, Seokchangpo, It may further include any one or more of herbal medicines such as mokhyang, sewage, astragalus, angelica, and jigolpi. At this time, the blending ratio of each component is preferably blended at the same weight ratio, but is not limited thereto.

In the method for preparing the composition for weight loss of the present invention, the hot water extraction step may be performed through hot water heating, and in addition to hot water extraction, extraction is performed by ultrasonic extraction, filtration, reflux extraction, immersion extraction, high temperature and high pressure steam extraction, etc. It may be performed alone or in combination of two or more methods.

In addition, the type of extraction solvent used in the hot water extraction step of the present invention is not particularly limited, and any solvent known in the art may be used. Non-limiting examples of the extraction solvent include, but are not limited to, water (distilled water), alcohol, or a mixed solvent thereof.

The amount of water input for the hot water extraction of the present invention may be 1 to 60 times the weight based on the total weight of the herbal medicine, and the hot water extraction may be performed a plurality of times as needed. For example, after one hot water extraction, the hot water extract is filtered, water is added to the remaining residue, and the same hot water extraction process and the filtration process after extraction can be performed one or more times. When the hot water extraction process is performed a plurality of times, the hot water extract extracted from each time may be added.

The hot water extraction step of the present invention is preferably performed at a temperature range of 80 to 120 ° C. for 1 to 5 hours, but is not limited thereto.

After performing the hot water extraction step of the present invention, the extract of each extracted component may be used by reflux extraction with ethanol to obtain a filtrate, concentrated under reduced pressure, freeze-dried, and powdered.

The step of concentrating the hot-water extract of the present invention is a process of making a concentrate having a predetermined viscosity so that the finally formed powder can be coagulated well and formed in a predetermined shape. The process of making the concentrate may be a conventional concentration process, but may be, for example, a water bath using water, and more specifically, an ultra-high-temperature low-temperature vacuum concentrator may be used. By performing such concentration, there is an advantage that a high content of active ingredients can be consumed in a small amount compared to the case of using a non-concentrated extract as the hot water extracted liquid is highly concentrated by about 20 times.

The concentrating step of the present invention is preferably performed at a temperature range of 40 to 80 ° C, but is not limited thereto. At this time, the concentrating step may be performed for 1 to 10 hours, more preferably for 3 to 5 hours.

Freeze-drying the concentrated extract of the present invention is a process performed to prepare the composition for weight loss of the present invention in the form of powder or pills. At this time, in addition to freeze drying, a conventional drying process such as natural drying or hot air drying may be appropriately employed if necessary, and the drying time may be appropriately selected by a person skilled in the art according to the drying method.

On the other hand, the preparation method of the composition for weight loss of the present invention may further include mixing any one of a carrier, excipient, or diluent after the step of concentrating the hot water extract.

Redundant content is omitted in consideration of the complexity of the present specification, and terms not otherwise defined in the present specification have meanings commonly used in the technical field to which the present invention belongs.

Hereinafter, the present invention will be described in detail by examples. However, the following examples are merely illustrative of the present invention, and the content of the present invention is not limited by the following examples.

{Example and evaluation}

<Example 1>

20 parts by weight of Japanese pepper, 20 parts by weight of dermis, 20 parts by weight of root root, 20 parts by weight of lobules, 20 parts by weight of cinnamon, 20 parts by weight of green bark, and 20 parts by weight of fennel were mixed and immersed in water 6 times the weight of herbal medicine, 100 After preheating for 1 hour at ° C., hot water extraction was performed for 3 hours. The obtained hot water extract (hot water extract) was concentrated to a volume of 1/40 of the volume of the hot water extract before concentration using a high-speed low-temperature vacuum concentrator at 60 ° C. to prepare a concentrate. Then, the concentrate (concentrated extract) was freeze-dried to prepare pills through a powdering process.

<Example 2>

It was prepared in the same manner as in Example 1, but the pills were prepared by changing the ingredients as shown in Table 1 below.

<Example 3>

20 parts by weight of Japanese pepper, 20 parts by weight of dermis, 20 parts by weight of root root, 20 parts by weight of lobules, 20 parts by weight of cinnamon, 20 parts by weight of green bark, and 20 parts by weight of fennel were mixed and immersed in water 6 times the weight of herbal medicine, 100 After preheating for 1 hour at ° C., hot water extraction was performed for 3 hours. Thereafter, a first hot water extract (hot water extract) was obtained, and the filtered remaining herbal medicine was subjected to hot water extraction under the same conditions and filtered to obtain a second hot water extract. After combining the obtained first and second hot-water extracts, a concentrate was prepared by concentrating the volume to 1/40 of the volume of the hot-water extract before concentration using a high-speed low-temperature vacuum concentrator at 60 ° C. Then, the concentrate (concentrated extract) was freeze-dried to prepare pills through a powdering process.

<Comparative Examples 1 to 7>

It was prepared in the same manner as in Example 1, but the pills were prepared by changing the ingredients as shown in Table 1 below.

<Experimental example>

After evaluating the weight loss effect for patients with a waist circumference of 90 cm for men and 85 cm for women based on adults among patients who visited an oriental medical clinic for obesity treatment, the results are shown in Table 1 below. Specifically, waist circumference and weight were measured for each patient at the first visit. Afterwards, all patients were asked to take the same number of pills for 60 days, and the patients were instructed to exercise or diet appropriate to their circumstances, but not to exercise excessively, fast or fast.

After continuously taking the pills according to Examples and Comparative Examples by 30 people (15 males and 15 females) for each Example and Comparative Example, the waist circumference and weight of each patient were measured in the same manner after 60 days. The degree of reduction compared to the waist circumference at the time of the first visit was calculated as a percentage for each patient, and the percentage reduction in the waist circumference for 30 patients was calculated as an average value for each example/comparative example.

In addition, after the first visit, while taking the pill, a questionnaire was asked about the change in the usual feeling of satiety during the 60 days. In preparation for the first visit, 0 if there was no change in satiety, 1 if the feeling of satiety slightly increased, 2 if the feeling of moderate increase, and 2 if it increased slightly. The survey result values based on case 3 and large increase 4 were summed and averaged. It can be interpreted that the higher the survey result value, the greater the increase in satiety.

In addition, it was evaluated whether side effects such as headache and insomnia occurred during 60 days while taking the pill after the first diagnosis, and the number of patients who felt these side effects for more than 3 days in 60 days was counted and calculated as a percentage.

<evaluation>

Example 1 Example 2 Example 3 Comparative Example 1 Comparative Example 2 Chinese pepper (parts by weight) 20 30 20 not included 20 Dermis (by weight) 20 30 20 20 not included Roots (parts by weight) 20 30 20 20 20 Leaflets (parts by weight) 20 30 20 20 20 Cinnamon (by weight) 20 30 20 20 20 Green skin (parts by weight) 20 30 20 20 20 Fennel (parts by weight) 20 30 20 20 20 Hot water extraction (time) One One 2 One One Average weight of 30 patients at first visit (kg) 72.8 70.4 74.8 73.6 72.0 Percentage of persons who lost less than 3% of body weight after evaluation (%) 10 6.7 3.3 20 30 Percentage of persons who lost more than 6% of body weight after evaluation (%) 63.3 76.7 80 53.3 56.7 Average decrease in waist circumference (%) 4.4 4.8 5.0 3.3 3.1 satiety 3.3 3.5 3.8 2.4 2.6 Side effect detection rate (%) 6.7 3.3 0 26.7 16.7 Comparative Example 3 Comparative Example 4 Comparative Example 5 Comparative Example 6 Comparative Example 7 Chinese pepper (parts by weight) 20 20 20 20 20 Dermis (by weight) 20 20 20 20 20 Roots (parts by weight) not included 20 20 20 20 Leaflets (parts by weight) 20 not included 20 20 20 Cinnamon (by weight) 20 20 not included 20 20 Green skin (parts by weight) 20 20 20 not included 20 Fennel (parts by weight) 20 20 20 20 not included Hot water extraction (time) One One One One One Average weight of 30 patients at first visit (kg) 71.5 70.8 74.4 72.3 73.9 Percentage of persons who lost less than 3% of body weight after evaluation (%) 33.3 23.3 46.7 36.7 40 Percentage of persons who lost more than 6% of body weight after evaluation (%) 56.7 53.3 36.7 46.7 50 Average decrease in waist circumference (%) 2.7 2.9 3.3 3.7 3.6 satiety 2.9 3.0 2.2 2.0 2.7 Side effect detection rate (%) 13.3 16.7 20 23.3 13.3

Referring to Table 1, it can be confirmed that the patient group taking the pill prepared by the composition for weight loss according to the embodiment of the present invention exhibits excellent weight loss effect with little or no side effects.

Compared to the composition according to the comparative example, the composition for weight loss according to the embodiment of the present invention includes all of pepper, dermis, gal root, lobules, cinnamon, green bark, and fennel, and each compounding ratio is formulated in the same ratio, so that the weight is reduced. The ratio of personnel who lost more than 6% was relatively high at 63.3%, 76.7%, and 80%, respectively, and while there was no or low side effect detection rate, it could be seen that the feeling of satiety remained rather high.

Therefore, the composition for weight loss and the manufacturing method of the present invention contain natural oriental medicines excellent in weight loss effect, such as Japanese pepper and dermis, in an optimal ratio, thereby effectively reducing body weight without any side effects on the human body, thereby preventing overweight or obesity. It has the effect of preventing various diseases caused by it.

The above description is merely an example of the technical idea of the present invention, and various modifications and variations can be made to those skilled in the art without departing from the essential characteristics of the present invention.

Therefore, the embodiments disclosed in the present invention are not intended to limit the technical idea of the present invention, but to explain, and the scope of the technical idea of the present invention is not limited by these embodiments. The protection scope of the present invention should be construed according to the claims below, and all technical ideas within the equivalent range should be construed as being included in the scope of the present invention.

Claims (10)

A composition for weight loss comprising sansho, dermis, radish root, lobules, cinnamon, green rind and fennel.
According to claim 1,
The Japanese pepper is 1 to 30 parts by weight, the dermis is 1 to 30 parts by weight, the root is 1 to 30 parts by weight, the lobules are 1 to 30 parts by weight, the cinnamon is 1 to 30 parts by weight, the green bark is 1 to 30 parts by weight 30 parts by weight and the fennel comprises 1 to 30 parts by weight, a composition for weight loss.
According to claim 1,
The pepper, dermis, root root, lobules, cinnamon, green skin and fennel are characterized in that they are included in the same weight, a composition for weight loss.
According to claim 1,
The weight loss composition is a composition for weight loss, characterized in that the hot water extract.
According to claim 1,
The composition for weight loss is a composition for weight loss, characterized in that the powder or pills obtained by drying the hot water extract.
According to claim 1,
A composition for weight loss, characterized in that it further comprises any one of a carrier, excipient or diluent.
Hot water extraction step by combining Japanese pepper, dermis, root of root, lobules, cinnamon, green skin and fennel;
Concentrating the hot water extract; and
Freeze-drying the concentrated extract; containing, a method for producing a composition for weight loss.
According to claim 7,
The hot water extraction step is characterized in that carried out for 1 to 5 hours at a temperature range of 80 to 120 ℃, a method for producing a composition for weight loss.
According to claim 7,
The method of preparing a composition for weight loss, characterized in that the concentrating step is carried out at a temperature range of 40 to 80 ℃.
According to claim 7,
Method for producing a composition for weight loss, further comprising the step of mixing any one of a carrier, excipient or diluent after the step of concentrating the hot water extract.