KR20230002766A - 내분비 교란물질 수용체에 상호작용하는 핵산 및 그의 이용 - Google Patents

내분비 교란물질 수용체에 상호작용하는 핵산 및 그의 이용 Download PDF

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KR20230002766A
KR20230002766A KR1020227039939A KR20227039939A KR20230002766A KR 20230002766 A KR20230002766 A KR 20230002766A KR 1020227039939 A KR1020227039939 A KR 1020227039939A KR 20227039939 A KR20227039939 A KR 20227039939A KR 20230002766 A KR20230002766 A KR 20230002766A
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Korean (ko)
Inventor
마사히로 오가와
사요코 하라시마
마사노부 카와니시
타카시 야지
Original Assignee
구미아이 가가쿠 고교 가부시키가이샤
코우리츠 다이가꾸 호우진 오사카
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Publication of KR20230002766A publication Critical patent/KR20230002766A/ko
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43509—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from crustaceans
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43563—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2330/00—Production
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/142—Toxicological screening, e.g. expression profiles which identify toxicity

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Insects & Arthropods (AREA)
  • Endocrinology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
KR1020227039939A 2020-04-21 2021-04-20 내분비 교란물질 수용체에 상호작용하는 핵산 및 그의 이용 Pending KR20230002766A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JPJP-P-2020-075196 2020-04-21
JP2020075196 2020-04-21
PCT/JP2021/016086 WO2021215451A1 (ja) 2020-04-21 2021-04-20 内分泌攪乱物質受容体に相互作用する核酸及びその利用

Publications (1)

Publication Number Publication Date
KR20230002766A true KR20230002766A (ko) 2023-01-05

Family

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KR1020227039939A Pending KR20230002766A (ko) 2020-04-21 2021-04-20 내분비 교란물질 수용체에 상호작용하는 핵산 및 그의 이용

Country Status (5)

Country Link
US (1) US20230250436A1 (https=)
EP (1) EP4141102A4 (https=)
JP (1) JPWO2021215451A1 (https=)
KR (1) KR20230002766A (https=)
WO (1) WO2021215451A1 (https=)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5754681B2 (https=) 1977-12-23 1982-11-19

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002000272A (ja) * 2000-06-21 2002-01-08 Mitsubishi-Tokyo Pharmaceuticals Inc ファージディスプレイ法で使用するための発現ベクター及びその利用
JP5754681B2 (ja) 2008-05-14 2015-07-29 国立研究開発法人農業生物資源研究所 幼若ホルモン応答エレメント
KR101241769B1 (ko) * 2011-02-14 2013-03-25 성균관대학교산학협력단 써모코커스 씰러리크레센스 균주 유래의 ｄｎａ 중합효소 및 돌연변이 써모코커스 씰러리크레센스 ａ７５２ｋ/ｎ２１３ｄ ｄｎａ 중합효소와 이들의 이용
JP2020039279A (ja) * 2018-09-07 2020-03-19 クミアイ化学工業株式会社 形質転換体及び当該形質転換体を用いた供試物質の評価方法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5754681B2 (https=) 1977-12-23 1982-11-19

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
[비특허문헌 1] Qianyu He, et al., Heat Shock Protein 83 (Hsp83) Facilitates Methoprene-tools(Met) Nuclear Import to Modulate Juvenile Hormone Signaling Journal of Biological Chemistry.289, (2014) p.27874-27885.
[비특허문헌 2] Norihisa Tatarazako, et al., Juvenile hormone agonists affect the occurrence of male Daphnia. Chemosphere.53, (2003) p.827-833.
[비특허문헌 3] Kenji Toyota, et al., Methyl farnesoate synthesis is necessary for the environmental sex determination in the water flea Daphnia pulex. Journal of Insect Physiology.80, (2015) p.22-30
[비특허문헌 4] Helen Ying Wang, et al., The screening of chemicals for juvenoid-related endocrine activity using the water flea Daphnia magna, Aquatic Toxicology 74, (2005) p.193-204
[비특허문헌 5] Tomas A. Gorr, et al., Acandidate juvenoid hormone receptor cis-element in the Daphnia magna hb2 hemoglobingene promoter, Molecular and Cellular Endocrinology 247, (2006) p.91-102
[비특허문헌 6] Nur Syafiqah Mohamad Ishak, et al., Co-option of the bZIP transcription factor Vrille as the activator of Doublesex 1 in environmental sex determination of the crustacean Daphnia magna 13, (2017) e1006953.

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WO2021215451A1 (ja) 2021-10-28
EP4141102A4 (en) 2024-05-29
EP4141102A1 (en) 2023-03-01
JPWO2021215451A1 (https=) 2021-10-28
US20230250436A1 (en) 2023-08-10

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