KR20210122810A - 청소년 특발성 관절염을 치료하기 위한 항 il-6 수용체 항체 - Google Patents

청소년 특발성 관절염을 치료하기 위한 항 il-6 수용체 항체 Download PDF

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Publication number
KR20210122810A
KR20210122810A KR1020217027293A KR20217027293A KR20210122810A KR 20210122810 A KR20210122810 A KR 20210122810A KR 1020217027293 A KR1020217027293 A KR 1020217027293A KR 20217027293 A KR20217027293 A KR 20217027293A KR 20210122810 A KR20210122810 A KR 20210122810A
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South Korea
Prior art keywords
antibody
week
once
subject
dose
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KR1020217027293A
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English (en)
Korean (ko)
Inventor
리디 바렛-코르멜
타냐 몸타헨
스테파노 피오레
자넷 반 아델스버그
Original Assignee
사노피 바이오테크놀로지
리제너론 파아마슈티컬스, 인크.
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Publication of KR20210122810A publication Critical patent/KR20210122810A/ko
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
KR1020217027293A 2019-01-31 2020-01-31 청소년 특발성 관절염을 치료하기 위한 항 il-6 수용체 항체 Pending KR20210122810A (ko)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201962799698P 2019-01-31 2019-01-31
US62/799,698 2019-01-31
US201962851474P 2019-05-22 2019-05-22
US62/851,474 2019-05-22
US201962935395P 2019-11-14 2019-11-14
US62/935,395 2019-11-14
EP19306553 2019-12-03
EP19306553.9 2019-12-03
PCT/US2020/016203 WO2020160465A1 (en) 2019-01-31 2020-01-31 Anti-il-6 receptor antibody for treating juvenile idiopathic arthritis

Publications (1)

Publication Number Publication Date
KR20210122810A true KR20210122810A (ko) 2021-10-12

Family

ID=69646033

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020217027293A Pending KR20210122810A (ko) 2019-01-31 2020-01-31 청소년 특발성 관절염을 치료하기 위한 항 il-6 수용체 항체

Country Status (15)

Country Link
US (2) US11498969B2 (https=)
EP (1) EP3917618A1 (https=)
JP (2) JP7542543B2 (https=)
KR (1) KR20210122810A (https=)
CN (1) CN114206442A (https=)
AU (2) AU2020216978B2 (https=)
BR (1) BR112021014377A2 (https=)
CA (1) CA3128212A1 (https=)
CO (1) CO2021011352A2 (https=)
IL (1) IL284890A (https=)
MA (1) MA54861A (https=)
MX (1) MX2021009242A (https=)
SG (1) SG11202107735SA (https=)
TW (2) TWI860325B (https=)
WO (1) WO2020160465A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112021014377A2 (pt) * 2019-01-31 2021-12-28 Regeneron Pharma Composições e métodos para o tratamento de artrite idiopática juvenil
AU2020261431A1 (en) 2019-04-24 2021-12-09 Regeneron Pharmaceuticals, Inc. Methods of diagnosis and treatment of rheumatoid arthritis
EP3980459A1 (en) 2019-06-04 2022-04-13 Sanofi Biotechnology Compositions and methods for treating pain in subj ects with rheumatoid arthritis
EP4593035A1 (en) * 2024-01-24 2025-07-30 Sanofi Predicting disease severity

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CA3128212A1 (en) 2020-08-06
TW202521583A (zh) 2025-06-01
CO2021011352A2 (es) 2021-12-10
JP2024161517A (ja) 2024-11-19
AU2020216978B2 (en) 2025-09-25
TW202043285A (zh) 2020-12-01
EP3917618A1 (en) 2021-12-08
MA54861A (fr) 2021-12-08
IL284890A (en) 2021-08-31
JP7542543B2 (ja) 2024-08-30
US20200339693A1 (en) 2020-10-29
BR112021014377A2 (pt) 2021-12-28
US20230127528A1 (en) 2023-04-27
SG11202107735SA (en) 2021-08-30
MX2021009242A (es) 2021-10-26
AU2020216978A1 (en) 2021-09-09
JP2022519828A (ja) 2022-03-25
WO2020160465A1 (en) 2020-08-06
TWI860325B (zh) 2024-11-01
AU2025279833A1 (en) 2026-01-22
WO2020160465A9 (en) 2020-10-15
CN114206442A (zh) 2022-03-18
US11498969B2 (en) 2022-11-15

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