KR20210068340A - Electroencephalogram assembly having nir irradiation part - Google Patents

Abstract

An object of the present invention is to provide an electroencephalogram electrode having a near-infrared irradiating unit capable of sensing an electrical signal of the brain in real-time during electroencephalogram measurement and stimulating the brain with near-infrared rays. According to the present invention, an electroencephalogram measurement electrode assembly has a plurality of electroencephalogram measurement electrodes including a plurality of electrode protrusion units and light irradiation protrusion units positioned at the center of the electrode protrusion units to emit near-infrared rays. The plurality of electroencephalogram measurement electrodes are disposed on a user's scalp at predetermined intervals and are connected to an electronic device so that the light irradiation protrusion units of the electroencephalogram measurement electrodes selectively irradiate light so as to apply light stimulation only to a specific part of the scalp and allow the electrode protrusion units to perform electroencephalogram measurement.

Description

Brain conduction measurement electrode having a near-infrared irradiation unit {ELECTROENCEPHALOGRAM ASSEMBLY HAVING NIR IRRADIATION PART}

The present invention relates to a brain conduction measuring electrode having a near-infrared irradiator.

Traumatic brain injury (TBI), stroke, multiple sclerosis (MS), schizophrenia, autism, insomnia, post-traumatic stress disorder (PTSD), dementia and Alzheimer's disease (Alzheimer's), Parkinson's disease (Parkinson's) And for chronic brain diseases such as many other neurological conditions and disorders, there are many side effects and disadvantages for treatment using pharmaceuticals.

For this, brain stimulation, one of the alternative therapies, has been used for some time, based on the fact that the nervous system responds to these techniques in a substantial way. Many of these technologies are based on electromagnetic shocks.

Brain stimulation can be broadly divided into invasive brain stimulation and non-invasive brain stimulation. An example of the invasive brain stimulation technique is Electric Stimulration through implanted eletrodes, which is a method of inserting electrodes into the base of the brain and applying electrical stimulation to control abnormal neural circuits. In the case of electrode implantation brain stimulation, the deep brain (thalamus, basal ganglia, and subthalamic nucleus of the diencephalon) can be stimulated. Therefore, it is used as a treatment method to improve symptoms of abnormal motor diseases such as Parkinson's disease, essential tremor, and dystonia. The disadvantage is that it requires surgery to insert electrodes and stimulation generators into the body.

Non-invasive brain stimulation methods include Transcranial Magnetic Stimulation (TMS) and Transcranial Direct-Current Stimulation (TDCS). TMS and TDCS technologies cannot stimulate the brain center due to their low penetrating power.

In addition, transcranial ultrasound stimulation and near-infrared stimulation (NIS) are safer than invasive brain stimulation methods, and unlike TMS and TDCS, deep brain stimulation is possible.

Near-infrared (NIR), mitochondrial CCO enzyme (Cytochrome C Oxidase) absorbs near-infrared rays and increases ATP (Adenosine triphosphate; main energy source in the human body) production. In addition, it stimulates vascular endothelial cells and red blood cells to increase the production of nitric oxide (NO, nitric oxide; prevents blood clotting, relaxes smooth muscle). The CCO stimulation effect is best at a wavelength of 810 nm. When ATP is increased, it promotes cell metabolism and energy to regenerate cells and prevent cell death. When NO increases in the body, blood vessels expand and blood flow increases, and the amount of oxygen supplied to the brain also increases, improving memory and cognitive function.

These near-infrared rays can pass through the skull and penetrate the brain. It can penetrate (when shaved) to an average depth of 23.6 mm (depth from the scalp) through the skull and scalp. However, the near-infrared wavelength had a weak point in terms of transmittance to hair. In the case of the ear canal, there is no hair and the skull is pierced (external acoustic meatus). Therefore, when NIR is irradiated through the ear canal, it is less affected by hair, skull, scalp, etc. that can absorb NIR, and when NIR is irradiated from both directions, intensive light stimulation (focusing) is possible in the center of the brain. there is this

On the other hand, the temperature distribution of the brain at normal body temperature (36.5 ℃) is 35.6 ~ 36.1 ℃, and when the brain temperature reaches 42 ℃, the brain tissue is degenerated or destroyed due to heat. If the brain temperature rises more than 6℃ from the normal temperature distribution, it becomes dangerous.

Irradiation of NIR can be a factor in increasing brain temperature. Therefore, the temperature rise can be controlled by repeatedly applying NIR to a wavelength of a short pulse width. Temperature rise should be prevented by controlling the pulse width and frequency and duration of irradiation and limiting the adjustable range.

On the other hand, electroencephalography records the electrical activity of the brain from electrodes attached to various places on the scalp, and is often used for sleep studies, monitoring of deep anesthesia, diagnosing epilepsy, and other diseases or dysfunctions of the brain and normal brain function. It appears differently depending on the state of mind and body, and serves as an index to measure the brain activity.

Electroencephalography measures the flow of electricity generated when a signal is transmitted between the cranial nerves in the nervous system by attaching electrodes to the scalp or cortex. Use a wet electrode used with conductive gel or a dry electrode that does not use conductive gel. Can be used.

When measuring using multi-channel electrodes, electroencephalography is measured by attaching multi-channel electrodes to the scalp so that they are evenly distributed according to international standards as shown in FIG. 1 .

In the conventional electroencephalogram measurement, when stimulation is applied to a part of the brain and the response is observed, electrical stimulation has a disadvantage in that interference occurs on the electroencephalogram measurement signal.

Republic of Korea Patent Registration No. 10-1912166

An object of the present invention is to provide an electroencephalogram electrode having a near-infrared irradiator capable of sensing an electrical signal of the brain in real time during electroencephalogram measurement and stimulating the brain with near-infrared rays.

Electroencephalogram measurement electrode assembly having a near-infrared irradiator according to the present invention is provided with a plurality of electroencephalogram measuring electrodes including; a plurality of electrode protrusions, and a light irradiation protrusion positioned at the center of the electrode protrusions to emit near-infrared rays The electrodes are arranged on the user's scalp at predetermined intervals, and are connected to an electronic device so that the light irradiation protrusions of the electroencephalogram measuring electrodes selectively irradiate light, so that light stimulation is applied only to a specific part of the scalp, and the electrode protrusions measure the electroencephalogram.

In addition, it is preferable that the intensity of light irradiated to a specific part of the scalp is adjusted.

In addition, it is preferable that the light irradiation characteristics of the light irradiation protrusions are controlled within a predetermined range.

In addition, it is preferable that the light irradiation characteristics include a frequency and a pulse width of the light.

In addition, it is preferable that the light intensity of the light irradiation protrusion of each of the electroencephalogram measuring electrodes is also controlled.

In addition, it is preferable that the light irradiation protrusion includes a near-infrared transmissive window in a portion in contact with the skin, and an LED emitting near-infrared light is installed in the window.

In addition, the light irradiation protrusion is provided with an LED emitting near-infrared rays at the end, it is preferable that the LED is in close contact with the scalp when the electrode is attached.

The electroencephalogram electrode provided with the near-infrared irradiator provided by the present invention has the advantage of being able to sense the brain stimulation effect in real time by stimulating the brain with near-infrared rays while simultaneously sensing the electrical signal of the brain.

In addition, there is an advantage in that only the core part can be stimulated because the brain can be stimulated in a certain range over the entire scalp, light is selectively irradiated to a specific area, and the intensity of each light can be adjusted.

1 is a diagram showing the electrode placement standard when taking multi-channel electrode electroencephalography;
2 is a view of a brain conduction measuring electrode having a near-infrared irradiation unit according to a first embodiment of the present invention;
Figure 3 is a view showing in detail the near-infrared irradiation unit provided in the brain conduction measuring electrode according to the first embodiment of the present invention;
4 is a view schematically showing a state in which the brain conduction measurement electrode according to the first embodiment of the present invention is attached to the user;
5 is a diagram of a brain conduction measuring electrode having a near-infrared irradiation unit according to a second embodiment of the present invention;
Figure 6 shows an example of stimulating the brain using a brain conduction measuring electrode having a near-infrared irradiator according to the present invention.

Hereinafter, the present invention will be described in more detail with reference to the drawings.

Figure 2 is a diagram of a brain conduction measuring electrode having a near-infrared irradiator according to a first embodiment of the present invention, Figure 3 is a view showing in detail the near-infrared irradiator provided in the brain conduction measuring electrode according to the first embodiment of the present invention to be.

The brain conduction measuring electrode 100 according to the first embodiment of the present invention includes a plurality of electrode protrusions 110 , and a light irradiation protrusion 120 is provided at the center of the electrode protrusions 110 .

The light irradiation protrusion 120 is provided with a window 122 formed of a light-transmitting, particularly near-infrared transmissive material at an end thereof, and a near-infrared irradiation device is installed in the window 122 . The near-infrared irradiation device is generally an LED capable of emitting near-infrared rays, and it is particularly preferable to generate near-infrared rays of 750 nm to 1300 nm.

The brain conduction measuring electrode 100 may be connected to a computer or a medical terminal by wire or wirelessly. Accordingly, the measured value measured by the electrode protrusion 110 is transmitted and recorded to a computer, medical terminal, mobile device, etc., and light irradiation characteristics (frequency, pulse width, etc.) of the irradiation device provided in the light irradiation protrusion 120 . can be controlled by the user within a predetermined range, and it is preferable that the light intensity for each brain conduction measuring electrode 100 can also be controlled by the user.

As the brain conduction measurement electrode 100 includes a near-infrared irradiator, the brain can be stimulated without signal interference using near-infrared rays even during EEG measurement.

4 is a view schematically showing a state in which the brain conduction measuring electrode according to the first embodiment of the present invention is attached to the user. A plurality of brain conduction measuring electrodes 100 are arranged at predetermined intervals on the user's scalp according to the standard. It is possible to measure brain conduction by the electrode protrusion 110 of the brain conduction measurement electrode 100 and to stimulate the brain using a near-infrared irradiation device installed at the end of the light irradiation protrusion 120 .

5 is a diagram of a brain conduction measuring electrode having a near-infrared irradiator according to a second embodiment of the present invention. The brain conduction measuring electrode 100a according to the second embodiment of the present invention is the same as the first embodiment in that it includes a plurality of electrode protrusions 110a and a light irradiation protrusion 120a at the center of the electrode protrusions 110a. Do. It differs from the first embodiment in that a recess is formed at the end of the light irradiation protrusion 120a, and a light irradiation device 122a for irradiating near-infrared rays is installed in the groove. The light irradiation device 122a is generally an LED capable of emitting near-infrared rays.

6 shows an example of stimulating the brain using a brain conduction measuring electrode having a near-infrared irradiator according to the present invention. As described above, by controlling the light irradiation characteristics (frequency, pulse width, etc.) of the near-infrared radiation emitted by the light irradiation device, it is possible to stimulate only a specific part or to vary the intensity of the light stimulus for each part.

100: brain conduction measurement electrode 110: electrode projection
120: light irradiation protrusion

Claims (7)

Provided with a plurality of electroencephalogram measuring electrodes comprising a plurality of electrode protrusions, and a light irradiation protrusion positioned at the center of the electrode protrusions to emit near-infrared rays,
A plurality of electroencephalogram measurement electrodes are arranged on the user's scalp at predetermined intervals, and are connected to an electronic device so that the light irradiation protrusions of the electroencephalogram measuring electrodes selectively irradiate light, so that light stimulation is applied only to a specific part of the scalp, and the electrode protrusions perform electroencephalography Electroencephalogram measurement electrode assembly having a near-infrared irradiator, characterized in that for measuring. The method of claim 1,
Electroencephalogram measurement electrode assembly having a near-infrared irradiator, characterized in that the intensity of light irradiated to a specific part of the scalp is adjusted. 3. The method according to claim 1 or 2,
Electroencephalogram measurement electrode assembly having a near-infrared irradiator, characterized in that the light irradiation characteristics of the light irradiation protrusions are controlled within a predetermined range. 4. The method of claim 3,
Light irradiation characteristics are electroencephalogram measurement electrode assembly having a near-infrared irradiation unit, characterized in that the light includes a frequency and a pulse width. The method of claim 1,
Electroencephalogram measurement electrode assembly having a near-infrared irradiator, characterized in that the light intensity of the light irradiation protrusion of each of the electroencephalogram measurement electrodes is also controlled. The method of claim 1,
The light irradiation protrusion includes a near-infrared transmissive window in a portion in contact with the skin, and an electroencephalogram measuring electrode assembly having a near-infrared irradiator, characterized in that an LED emitting near-infrared light is installed in the window. The method of claim 1,
An electroencephalogram measuring electrode assembly having a near-infrared irradiating part, characterized in that the light-irradiating protrusion is provided with an LED emitting near-infrared radiation at its end, and the LED is in close contact with the scalp when the electrode is attached.

Images