KR20200116477A - 플리나불린 및 g-csf 제제의 투여를 통해 화학요법-유도된 호중구감소증을 감소시키기 위한 조성물 및 방법 - Google Patents

플리나불린 및 g-csf 제제의 투여를 통해 화학요법-유도된 호중구감소증을 감소시키기 위한 조성물 및 방법 Download PDF

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KR20200116477A
KR20200116477A KR1020207024515A KR20207024515A KR20200116477A KR 20200116477 A KR20200116477 A KR 20200116477A KR 1020207024515 A KR1020207024515 A KR 1020207024515A KR 20207024515 A KR20207024515 A KR 20207024515A KR 20200116477 A KR20200116477 A KR 20200116477A
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csf
plinabulin
administration
minutes
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라몬 모한랄
란 황
조지 케네스 로이드
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비욘드스프링 파마수티컬스, 인코포레이티드.
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    • A—HUMAN NECESSITIES
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

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  • Physical Education & Sports Medicine (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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KR1020207024515A 2018-02-01 2019-01-30 플리나불린 및 g-csf 제제의 투여를 통해 화학요법-유도된 호중구감소증을 감소시키기 위한 조성물 및 방법 Ceased KR20200116477A (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020267003258A KR20260023097A (ko) 2018-02-01 2019-01-30 플리나불린 및 g-csf 제제의 투여를 통해 화학요법-유도된 호중구감소증을 감소시키기 위한 조성물 및 방법

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201862625290P 2018-02-01 2018-02-01
US62/625,290 2018-02-01
US201862713486P 2018-08-01 2018-08-01
US62/713,486 2018-08-01
US201862749060P 2018-10-22 2018-10-22
US62/749,060 2018-10-22
US201862757648P 2018-11-08 2018-11-08
US62/757,648 2018-11-08
PCT/US2019/015867 WO2019152530A1 (en) 2018-02-01 2019-01-30 Composition and method for reducing chemotherapy-induced neutropenia via the administration of plinabulin and a g-csf agent

Related Child Applications (1)

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KR1020267003258A Division KR20260023097A (ko) 2018-02-01 2019-01-30 플리나불린 및 g-csf 제제의 투여를 통해 화학요법-유도된 호중구감소증을 감소시키기 위한 조성물 및 방법

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KR20200116477A true KR20200116477A (ko) 2020-10-12

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KR1020207024515A Ceased KR20200116477A (ko) 2018-02-01 2019-01-30 플리나불린 및 g-csf 제제의 투여를 통해 화학요법-유도된 호중구감소증을 감소시키기 위한 조성물 및 방법
KR1020267003258A Pending KR20260023097A (ko) 2018-02-01 2019-01-30 플리나불린 및 g-csf 제제의 투여를 통해 화학요법-유도된 호중구감소증을 감소시키기 위한 조성물 및 방법

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US (1) US20210030843A1 (https=)
EP (1) EP3746076A4 (https=)
JP (3) JP2021512121A (https=)
KR (2) KR20200116477A (https=)
CN (1) CN112105363A (https=)
AU (1) AU2019216305B2 (https=)
BR (1) BR112020015758A2 (https=)
CA (1) CA3089391A1 (https=)
IL (1) IL276197A (https=)
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WO (1) WO2019152530A1 (https=)

Cited By (1)

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KR102375269B1 (ko) * 2021-01-27 2022-03-17 한미약품 주식회사 단백질 액상 제제 및 이의 제조방법

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MX383691B (es) 2015-03-06 2025-03-14 Beyondspring Pharmaceuticals Inc Método de tratamiento de cáncer asociado con una mutación de ras.
US10155748B2 (en) 2015-07-13 2018-12-18 Beyondspring Pharmaceuticals, Inc. Plinabulin compositions
WO2017139231A1 (en) 2016-02-08 2017-08-17 Beyondspring Pharmaceuticals, Inc. Compositions containing tucaresol or its analogs
RU2760348C2 (ru) 2016-06-06 2021-11-24 Бейондспринг Фармасьютикалс, Инк. Способ уменьшения нейтропении
JP2020503363A (ja) 2017-01-06 2020-01-30 ビヨンドスプリング ファーマシューティカルズ，インコーポレイテッド チューブリン結合化合物およびその治療的使用
BR112019015974A2 (pt) 2017-02-01 2020-03-31 Beyondspring Pharmaceuticals, Inc. Método para reduzir neutropenia
KR20200112881A (ko) 2018-01-24 2020-10-05 비욘드스프링 파마수티컬스, 인코포레이티드. 플리나불린의 투여를 통해 혈소판감소증을 감소시키는 조성물 및 방법
US11267858B2 (en) 2019-05-31 2022-03-08 Spectrum Pharmaceuticals, Inc. Methods of treatment using G-CSF protein complex
US11684655B2 (en) 2019-05-31 2023-06-27 Spectrum Pharmaceuticals, Inc. Methods of treating neutorpenia using G-CSF protein complex
EP4045046A4 (en) * 2019-10-15 2024-01-10 Beyondspring Pharmaceuticals Inc. Methods and compositions for treating iron disorders
JP2023505506A (ja) * 2019-12-05 2023-02-09 ハンミ ファーマシューティカルズ カンパニー リミテッド 化学療法または放射線療法で誘導された好中球減少症を治療する方法
CA3186416A1 (en) * 2020-07-17 2022-01-20 John A. Barrett Methods of treating chemotherapy induced neutropenia using fixed doses of g-csf protein complex
WO2022133492A1 (en) * 2020-12-18 2022-06-23 Beyondspring Pharmaceuticals, Inc. Compositions and methods for generating anti-tumor immune response
CA3215047A1 (en) 2021-04-09 2022-10-13 Lan Huang Therapeutic compositions and methods for treating tumors
CN113456643B (zh) * 2021-08-11 2022-04-01 遵义医科大学 一种含普那布林的药物组合及其应用
CN117860672A (zh) 2022-10-11 2024-04-12 大连万春布林医药有限公司 一种普那布林胶束组合物及其制备方法
FI131561B1 (en) * 2023-12-28 2025-06-30 Faron Pharmaceuticals Oy CLEVER-1 INHIBITOR TO PROMOTE HEMATOLOGICAL RECOVERY WHEN USING CHEMOTHERAPY
CN120682197A (zh) * 2024-03-19 2025-09-23 大连万春布林医药有限公司 普那布林的盐晶型
CN119371407A (zh) * 2024-06-27 2025-01-28 青岛海合生物科技有限公司 一种具有抗肿瘤功效的2,5-二酮哌嗪类化合物及其在制备治疗和/或预防中性粒细胞减少症的药物中的应用

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KR20110132327A (ko) * 2009-01-16 2011-12-07 테바 파마슈티컬 인더스트리즈 리미티드 재조합 인간 알부민-인간 과립구 콜로니 자극 인자 융합 단백질의 신규 안정한 제형
JP6411523B2 (ja) * 2013-10-11 2018-10-24 ビヨンドスプリング インコーポレイテッド プリナブリン及びタキサンの組合せがん治療
RU2760348C2 (ru) * 2016-06-06 2021-11-24 Бейондспринг Фармасьютикалс, Инк. Способ уменьшения нейтропении
BR112019015974A2 (pt) * 2017-02-01 2020-03-31 Beyondspring Pharmaceuticals, Inc. Método para reduzir neutropenia

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102375269B1 (ko) * 2021-01-27 2022-03-17 한미약품 주식회사 단백질 액상 제제 및 이의 제조방법
EP4284340A4 (en) * 2021-01-27 2024-12-11 Hanmi Pharm. Co., Ltd. LIQUID PROTEIN FORMULATION AND METHOD FOR THE PRODUCTION THEREOF

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US20210030843A1 (en) 2021-02-04
IL276197A (en) 2020-09-30
CA3089391A1 (en) 2019-08-08
SG11202006990TA (en) 2020-08-28
KR20260023097A (ko) 2026-02-20
JP2021512121A (ja) 2021-05-13
EP3746076A1 (en) 2020-12-09
WO2019152530A1 (en) 2019-08-08
JP2026026377A (ja) 2026-02-16
JP2024015120A (ja) 2024-02-01
RU2020126600A (ru) 2022-03-01
EP3746076A4 (en) 2021-12-22
NZ766454A (en) 2024-02-23
AU2019216305B2 (en) 2024-11-21
BR112020015758A2 (pt) 2020-12-08
AU2019216305A1 (en) 2020-08-27
CN112105363A (zh) 2020-12-18

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