KR20200032103A - 실크-히알루론산 기초 조직 충전제 및 이를 사용하는 방법 - Google Patents

실크-히알루론산 기초 조직 충전제 및 이를 사용하는 방법 Download PDF

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Publication number
KR20200032103A
KR20200032103A KR1020207002371A KR20207002371A KR20200032103A KR 20200032103 A KR20200032103 A KR 20200032103A KR 1020207002371 A KR1020207002371 A KR 1020207002371A KR 20207002371 A KR20207002371 A KR 20207002371A KR 20200032103 A KR20200032103 A KR 20200032103A
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KR
South Korea
Prior art keywords
tissue filler
spf
silk
kda
crosslinked
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Ceased
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KR1020207002371A
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English (en)
Korean (ko)
Inventor
그레고리 에이치. 알트만
펭 주
얼레이 진
Original Assignee
이발브드 바이 네이처, 인크.
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Publication of KR20200032103A publication Critical patent/KR20200032103A/ko
Ceased legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/20—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/26—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L89/00—Compositions of proteins; Compositions of derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/402—Anaestetics, analgesics, e.g. lidocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/06—Flowable or injectable implant compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/34—Materials or treatment for tissue regeneration for soft tissue reconstruction

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Dermatology (AREA)
  • Veterinary Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Materials For Medical Uses (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
KR1020207002371A 2017-06-26 2018-06-26 실크-히알루론산 기초 조직 충전제 및 이를 사용하는 방법 Ceased KR20200032103A (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762525131P 2017-06-26 2017-06-26
US62/525,131 2017-06-26
US201862641095P 2018-03-09 2018-03-09
US62/641,095 2018-03-09
PCT/US2018/039574 WO2019005848A1 (en) 2017-06-26 2018-06-26 HYALURONIC SILK ACID TISSUE FILLING AGENTS AND METHODS OF USE THEREOF

Publications (1)

Publication Number Publication Date
KR20200032103A true KR20200032103A (ko) 2020-03-25

Family

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Family Applications (1)

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KR1020207002371A Ceased KR20200032103A (ko) 2017-06-26 2018-06-26 실크-히알루론산 기초 조직 충전제 및 이를 사용하는 방법

Country Status (13)

Country Link
EP (2) EP4169539B1 (https=)
JP (3) JP2020525253A (https=)
KR (1) KR20200032103A (https=)
CN (1) CN111263646A (https=)
AU (2) AU2018290810C1 (https=)
CA (1) CA3068296A1 (https=)
CO (1) CO2020000774A2 (https=)
ES (2) ES2935887T3 (https=)
IL (2) IL299584A (https=)
MA (1) MA49520A (https=)
SG (1) SG11201913229PA (https=)
UA (1) UA127350C2 (https=)
WO (1) WO2019005848A1 (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20230013682A (ko) 2021-07-16 2023-01-27 주식회사 휴메딕스 Pegde로 가교된 히알루론산 필러 및 이의 제조방법
KR20230059749A (ko) * 2021-10-26 2023-05-03 엔케이디 파마 씨오., 엘티디 친수성 주사형 피부 충전 조성물 및 이의 제조 방법과 응용
KR102766244B1 (ko) * 2024-02-16 2025-02-10 충남대학교 산학협력단 Lc-ms/ms 기반의 히알루론산, bdde 및 bdde 가교된 히알루론산의 정량방법

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US20230190997A1 (en) 2017-06-26 2023-06-22 Evolved By Nature, Inc. Silk-hyaluronic acid based tissue filers and methods of using the same
JP6508431B1 (ja) 2017-09-21 2019-05-08 住友電気工業株式会社 半絶縁性ヒ化ガリウム結晶基板
AU2019405953B2 (en) * 2018-12-19 2025-09-18 Evolved By Nature, Inc. Silk-hyaluronic acid tissue fillers and methods of making and using the same
US20220193305A1 (en) * 2019-03-29 2022-06-23 Trustees Of Tufts College Crosslinked silk fibroin-based compositions, and methods of making and using the same
AU2020289479A1 (en) * 2019-06-06 2022-02-03 Evolved By Nature, Inc. Silk stimulated collagen production and methods of use thereof
WO2020262596A1 (en) * 2019-06-26 2020-12-30 Compagnie Generale Des Etablissements Michelin A noise improving tread
CN110339398A (zh) * 2019-07-18 2019-10-18 王月玲 一种含氨基酸透明质酸钠注射剂及其制备方法
EP4017537A4 (en) * 2019-08-20 2023-08-16 Evolved by Nature, Inc. SILK PERSONAL CARE PRODUCTS
EP3995530B1 (en) * 2019-09-27 2025-05-28 LG Chem, Ltd. A method of preparing polymer microparticles, polymer microparticles, medical composition, cosmetic composition, medical articles, and cosmetic articles using the same
PL4077402T3 (pl) * 2019-12-19 2024-07-29 Croma-Pharma Gmbh Kwas hialuronowy modyfikowany tiolem i hydrożel zawierający usieciowany kwas hialuronowy
CN116507315A (zh) * 2020-06-19 2023-07-28 自然进化公司 用于组织填充、组织间隔和组织膨胀的丝-透明质酸组合物
US20250295691A1 (en) * 2020-06-19 2025-09-25 Evolved By Nature, Inc. Silk-Hyaluronic Acid Compositions For Tissue Filling, Tissue Spacing, and Tissue Bulking
JP2024519426A (ja) * 2020-09-29 2024-05-14 ジロパ・インコーポレイテッド 疼痛の緩和及び麻痺のための組成物及び方法
TR202101065A1 (tr) * 2021-01-25 2022-08-22 Hacettepe Ueniversitesi Hyaluroni̇k asi̇t jel i̇çeren bi̇r doku dolgu malzemesi̇ ve üreti̇m yöntemi̇
CN114213517B (zh) * 2021-02-08 2024-07-09 复向丝泰医疗科技(苏州)有限公司 利用切向流超滤技术制备可控高浓度丝素蛋白溶液的方法
JP7695344B2 (ja) 2021-05-21 2025-06-18 ケンブリッジ クロップス インコーポレイテッド． ドゥーイングビジネスアズ モリ 絹フィブロイン溶液及び絹フィブロインを含む粉末を製造するためのシステム及び方法
WO2023275278A1 (en) * 2021-06-30 2023-01-05 Merz Pharma Gmbh & Co. Kgaa Hyaluronic acid dermal fillers crosslinked with polyethylene glycol diglycidyl ether, method for making same and uses thereof
CN113368220A (zh) * 2021-07-05 2021-09-10 云南维他源生物科技有限公司 一种ahco组合物及其制剂与应用
US11864569B2 (en) 2021-08-16 2024-01-09 Cambridge Crops, Inc. Systems and methods for improving the performance of cereal using a silk fibroin solution and powders containing silk fibroin

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EP3503841A4 (en) * 2016-08-24 2020-04-22 Allergan, Inc. CO-CROSSLINKED HYALURONIC ACID-FIBROIN HYDROGELS FOR IMPROVING THE SUSTAINABILITY OF TISSUE GRAFTS AND FOR INCREASING SOFT TISSUES

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20230013682A (ko) 2021-07-16 2023-01-27 주식회사 휴메딕스 Pegde로 가교된 히알루론산 필러 및 이의 제조방법
KR20230059749A (ko) * 2021-10-26 2023-05-03 엔케이디 파마 씨오., 엘티디 친수성 주사형 피부 충전 조성물 및 이의 제조 방법과 응용
KR102766244B1 (ko) * 2024-02-16 2025-02-10 충남대학교 산학협력단 Lc-ms/ms 기반의 히알루론산, bdde 및 bdde 가교된 히알루론산의 정량방법
WO2025173964A1 (ko) * 2024-02-16 2025-08-21 충남대학교산학협력단 Lc-ms/ms 기반의 히알루론산, bdde 및 bdde 가교된 히알루론산의 정량방법

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Publication number Publication date
JP2020525253A (ja) 2020-08-27
EP4169539A1 (en) 2023-04-26
AU2024219582A1 (en) 2024-10-03
ES2935887T3 (es) 2023-03-13
AU2018290810C1 (en) 2024-09-12
US20230338614A1 (en) 2023-10-26
UA127350C2 (uk) 2023-07-26
JP2025020289A (ja) 2025-02-12
EP3645063A4 (en) 2021-04-14
EP4169539B1 (en) 2025-01-29
EP4169539C0 (en) 2025-01-29
JP2023139249A (ja) 2023-10-03
WO2019005848A1 (en) 2019-01-03
AU2018290810B2 (en) 2024-06-13
JP7660619B2 (ja) 2025-04-11
EP3645063A1 (en) 2020-05-06
CN111263646A (zh) 2020-06-09
CA3068296A1 (en) 2019-01-03
CO2020000774A2 (es) 2020-05-05
IL299584A (en) 2023-03-01
SG11201913229PA (en) 2020-01-30
IL271692B2 (en) 2023-06-01
ES3018883T3 (en) 2025-05-19
IL271692A (en) 2020-02-27
EP3645063B1 (en) 2022-09-28
MA49520A (fr) 2021-04-14
AU2018290810A1 (en) 2020-02-13
BR112019027687A2 (pt) 2020-09-15

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