KR20190015625A - Ｄｐｐ-ｉｖ 억제제의 용도 - Google Patents

Ｄｐｐ-ｉｖ 억제제의 용도 Download PDF

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Publication number
KR20190015625A
KR20190015625A KR1020197003473A KR20197003473A KR20190015625A KR 20190015625 A KR20190015625 A KR 20190015625A KR 1020197003473 A KR1020197003473 A KR 1020197003473A KR 20197003473 A KR20197003473 A KR 20197003473A KR 20190015625 A KR20190015625 A KR 20190015625A
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KR
South Korea
Prior art keywords
diabetic
inhibitor
glucose
diabetes
treatment
Prior art date
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KR1020197003473A
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English (en)
Korean (ko)
Inventor
클라우스 두기
프랑크 힘멜스바흐
미하엘 마르크
Original Assignee
베링거 인겔하임 인터내셔날 게엠베하
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Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38235138&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR20190015625(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 베링거 인겔하임 인터내셔날 게엠베하 filed Critical 베링거 인겔하임 인터내셔날 게엠베하
Publication of KR20190015625A publication Critical patent/KR20190015625A/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/5025—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
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    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
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    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K9/20—Pills, tablets, discs, rods
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
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    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Hospice & Palliative Care (AREA)
  • Emergency Medicine (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Vascular Medicine (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Transplantation (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Reproductive Health (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Inorganic Chemistry (AREA)
KR1020197003473A 2006-05-04 2007-05-03 Ｄｐｐ-ｉｖ 억제제의 용도 KR20190015625A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP06009203.8 2006-05-04
EP06009203 2006-05-04
PCT/EP2007/054270 WO2007128761A2 (de) 2006-05-04 2007-05-03 Verwendungen von dpp iv inhibitoren

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1020177034831A Division KR20170136018A (ko) 2006-05-04 2007-05-03 Ｄｐｐ-ｉｖ 억제제의 용도

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020207031835A Division KR20200128209A (ko) 2006-05-04 2007-05-03 Ｄｐｐ-ｉｖ 억제제의 용도

Publications (1)

Publication Number Publication Date
KR20190015625A true KR20190015625A (ko) 2019-02-13

Family

ID=38235138

Family Applications (9)

Application Number Title Priority Date Filing Date
KR1020157017031A KR101655754B1 (ko) 2006-05-04 2007-05-03 Ｄｐｐ-ｉｖ 억제제의 용도
KR1020147008698A KR101558938B1 (ko) 2006-05-04 2007-05-03 Ｄｐｐ-ｉｖ 억제제의 용도
KR1020167024324A KR101806786B1 (ko) 2006-05-04 2007-05-03 Ｄｐｐ-ｉｖ 억제제의 용도
KR1020207031835A KR20200128209A (ko) 2006-05-04 2007-05-03 Ｄｐｐ-ｉｖ 억제제의 용도
KR1020177034831A KR20170136018A (ko) 2006-05-04 2007-05-03 Ｄｐｐ-ｉｖ 억제제의 용도
KR1020227034142A KR20220140016A (ko) 2006-05-04 2007-05-03 Ｄｐｐ-ｉｖ 억제제의 용도
KR1020087026975A KR20090021152A (ko) 2006-05-04 2007-05-03 Ｄｐｐ-ｉｖ 억제제의 용도
KR1020197003473A KR20190015625A (ko) 2006-05-04 2007-05-03 Ｄｐｐ-ｉｖ 억제제의 용도
KR1020147008699A KR20140048345A (ko) 2006-05-04 2007-05-03 Ｄｐｐ-ｉｖ 억제제의 용도

Family Applications Before (7)

Application Number Title Priority Date Filing Date
KR1020157017031A KR101655754B1 (ko) 2006-05-04 2007-05-03 Ｄｐｐ-ｉｖ 억제제의 용도
KR1020147008698A KR101558938B1 (ko) 2006-05-04 2007-05-03 Ｄｐｐ-ｉｖ 억제제의 용도
KR1020167024324A KR101806786B1 (ko) 2006-05-04 2007-05-03 Ｄｐｐ-ｉｖ 억제제의 용도
KR1020207031835A KR20200128209A (ko) 2006-05-04 2007-05-03 Ｄｐｐ-ｉｖ 억제제의 용도
KR1020177034831A KR20170136018A (ko) 2006-05-04 2007-05-03 Ｄｐｐ-ｉｖ 억제제의 용도
KR1020227034142A KR20220140016A (ko) 2006-05-04 2007-05-03 Ｄｐｐ-ｉｖ 억제제의 용도
KR1020087026975A KR20090021152A (ko) 2006-05-04 2007-05-03 Ｄｐｐ-ｉｖ 억제제의 용도

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020147008699A KR20140048345A (ko) 2006-05-04 2007-05-03 Ｄｐｐ-ｉｖ 억제제의 용도

Country Status (35)

Country Link
US (8) US8232281B2 (sl)
EP (5) EP4104838A1 (sl)
JP (12) JP5734564B2 (sl)
KR (9) KR101655754B1 (sl)
CN (8) CN102125560A (sl)
AR (1) AR060757A1 (sl)
AU (1) AU2007247141B2 (sl)
BR (1) BRPI0711308A2 (sl)
CA (4) CA2833705C (sl)
CL (3) CL2012002526A1 (sl)
CY (1) CY1115350T1 (sl)
DK (1) DK2015754T3 (sl)
EA (3) EA202091999A3 (sl)
EC (1) ECSP088866A (sl)
ES (2) ES2474866T3 (sl)
HK (1) HK1204548A1 (sl)
HR (1) HRP20140645T1 (sl)
IL (1) IL195031A0 (sl)
ME (1) ME01787B (sl)
MX (3) MX2008014025A (sl)
MY (3) MY174380A (sl)
NO (1) NO345061B1 (sl)
NZ (2) NZ609765A (sl)
PE (2) PE20080251A1 (sl)
PH (2) PH12013501791A1 (sl)
PL (1) PL2015754T3 (sl)
PT (2) PT2397142T (sl)
RS (1) RS53272B (sl)
SG (1) SG171648A1 (sl)
SI (1) SI2015754T1 (sl)
TW (2) TWI500423B (sl)
UA (1) UA102669C2 (sl)
UY (1) UY30321A1 (sl)
WO (1) WO2007128761A2 (sl)
ZA (1) ZA200808282B (sl)

Families Citing this family (123)

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EP2015754A2 (de) 2009-01-21
PH12013501790A1 (en) 2014-09-22
PH12013501791B1 (en) 2014-09-22
MY174380A (en) 2020-04-14
CA2833705A1 (en) 2007-11-15
CN101460173A (zh) 2009-06-17
JP2024028665A (ja) 2024-03-04
CN102125560A (zh) 2011-07-20
US20140135348A1 (en) 2014-05-15
ES2928734T3 (es) 2022-11-22
WO2007128761A3 (de) 2008-03-06
PE20110235A1 (es) 2011-04-14
PH12013501791A1 (en) 2014-09-22
ECSP088866A (es) 2008-12-30
KR101806786B1 (ko) 2017-12-08
KR20090021152A (ko) 2009-02-27
CN110227078A (zh) 2019-09-13
KR101655754B1 (ko) 2016-09-08
KR20160107361A (ko) 2016-09-13
US10080754B2 (en) 2018-09-25
TWI524894B (zh) 2016-03-11
ZA200808282B (en) 2009-08-26
US11291668B2 (en) 2022-04-05
MX358618B (es) 2018-08-29
KR101558938B1 (ko) 2015-10-08
AU2007247141A1 (en) 2007-11-15
JP2013199503A (ja) 2013-10-03
PL2015754T3 (pl) 2014-08-29
EA200802204A1 (ru) 2009-04-28

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