KR20170046027A - Device for Curing the ligament tendon using a Ultrasonic Waves Vibration - Google Patents

Device for Curing the ligament tendon using a Ultrasonic Waves Vibration Download PDF

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Publication number
KR20170046027A
KR20170046027A KR1020150146306A KR20150146306A KR20170046027A KR 20170046027 A KR20170046027 A KR 20170046027A KR 1020150146306 A KR1020150146306 A KR 1020150146306A KR 20150146306 A KR20150146306 A KR 20150146306A KR 20170046027 A KR20170046027 A KR 20170046027A
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KR
South Korea
Prior art keywords
tendon
contact
ultrasonic vibration
ligament
frequency
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Application number
KR1020150146306A
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Korean (ko)
Inventor
송해용
김학준
김성은
윤영필
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(주)오스힐
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Priority to KR1020150146306A priority Critical patent/KR20170046027A/en
Publication of KR20170046027A publication Critical patent/KR20170046027A/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61HPHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H39/00Devices for locating or stimulating specific reflex points of the body for physical therapy, e.g. acupuncture
    • A61H39/007Stimulation by mechanical vibrations, e.g. ultrasonic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61HPHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H23/00Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms
    • A61H23/02Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms with electric or magnetic drive
    • A61H23/0218Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms with electric or magnetic drive with alternating magnetic fields producing a translating or oscillating movement
    • A61H23/0236Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms with electric or magnetic drive with alternating magnetic fields producing a translating or oscillating movement using sonic waves, e.g. using loudspeakers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/06Electrodes for high-frequency therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61HPHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H2201/00Characteristics of apparatus not provided for in the preceding codes
    • A61H2201/10Characteristics of apparatus not provided for in the preceding codes with further special therapeutic means, e.g. electrotherapy, magneto therapy or radiation therapy, chromo therapy, infra-red or ultraviolet therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61HPHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H2201/00Characteristics of apparatus not provided for in the preceding codes
    • A61H2201/50Control means thereof

Abstract

Provided is a device for treatment of tendon ligaments using ultrasonic vibration.
The present invention relates to a contact portion which is brought into close contact with a body skin corresponding to a site where the tendon is damaged; An ultrasonic vibration generator for generating a sound wave to transmit a vibration at a shortest distance to a damaged part of the tendon through the skin in contact with the contact part; A controller for adjusting the intensity of the ultrasonic vibration generated in the ultrasonic vibration generator according to the position of the damage site of the tendon ligature separated from the contact portion; To increase the growth or activity of fibroblasts that synthesize collagen fibers associated with the tendon ligament.

Description

TECHNICAL FIELD [0001] The present invention relates to a device for treating ligament tendon using ultrasound vibration,
The present invention relates to a device for treating a tendon ligament, which transmits the generated ultrasonic vibration to a damaged tendon ligament, thereby activating and promoting the synthesis of collagen fibers associated with the tendon ligament, thereby regenerating and repairing the damaged tendon ligament rapidly The present invention relates to an apparatus for treating tendon ligaments using ultrasonic vibration.
Generally, tendon is a fibrous soft tissue that is called tendon and attaches muscle to bone. Ligament plays a strong tongue which acts to fix bone with bone to stabilize. To reduce the impact and to support the movement of the joint.
The number of injured ligaments, one of the connective tissues of the body, is increasing with the increase of various outdoor activities such as soccer and baseball.
However, if the tendon or ligament is twisted or overtrained by outdoor activities such as sports activities or an unexpected external impact in the room, it may cause ligament rupture or damage, and this injury may cause pain and prevent exercise or daily activities .
The tendon is a fibrous tissue that has the same texture as muscles and has a high connective tissue content. It is very strong and flexible, but it has no elasticity. It is a muscle tissue and muscles and bones which transmit muscle contraction force. The gun can be damaged when it is applied.
In addition, the supply of blood plays an important role in the healing of injured tissue. Most of the synovial membrane is destroyed with the collapse of ligament, such as anterior cruciate ligament and Achilles tendon, and the synovial membrane is damaged.
These tendon ligaments are mainly made of collagen. Once damaged, fibroblast, which is the most important cell in the connective tissue, forms collagen fiber. In the early stage of damage, collagen attaches to the damaged area in the form of gel, To play back naturally.
Therefore, it is very important to increase the synthesis of collagen for rapid recovery after the tendon injury.
However, if the ligament injuries are not treated immediately, it is impossible to regenerate 100% of the ligaments. If most athletes or ordinary people do not perform intensive treatment for injured ligaments, physical stress will cause collapse rather than synthesis of collagen. As the number of ligaments increases, ligaments are not able to heal, and 1 to 2 weeks of delayed damage can eventually cause chronic problems in months.
SUMMARY OF THE INVENTION Accordingly, the present invention has been made to solve the above-mentioned problems, and it is an object of the present invention to provide a collagen preparation device capable of increasing and promoting collagen synthesis in a short period of time, And to provide an apparatus for treating ligamentous tendon using ultrasonic vibration capable of improving the ability.
It is to be understood that both the foregoing general description and the following detailed description are exemplary and explanatory and are not restrictive of the invention, unless further departing from the spirit and scope of the invention as defined by the appended claims. It will be possible.
As a specific means for accomplishing the above object, a preferred embodiment of the present invention is a medical device comprising: a contact portion which is brought into close contact with a body skin corresponding to a damaged region of the tendon; An ultrasonic vibration generator for generating a sound wave to transmit a vibration at a shortest distance to a damaged part of the tendon through the skin in contact with the contact part; A controller for adjusting the intensity of the ultrasonic vibration generated in the ultrasonic vibration generator according to the position of the damage site of the tendon ligature separated from the contact portion; The present invention provides an apparatus for treatment of tendon ligaments using ultrasonic vibration, characterized by increasing the growth or activity of fibroblasts synthesizing collagen fibers associated with the tendon.
Preferably, the apparatus further comprises a high-frequency generating unit for generating a high-frequency wave to transmit the high-frequency heat at the shortest distance to the injury site of the tendon through the skin contacting the contact unit, The intensity of the high frequency generated in the high frequency generator can be controlled.
Preferably, the control unit controls the ultrasonic vibration and the high-frequency heat transmitted to the injury site of the tendon through the skin contacting the contact unit to be alternately generated at a predetermined period of time.
The present invention as described above has the following effects.
(1) Ultrasound vibration of a specific frequency band is transmitted to the damaged region of the tendon ligament which is ruptured or overpredicted by an external impact and an external force, or alternatively, high frequency heat and ultrasonic vibration are alternately transmitted, Can increase the growth or activity of cells because it can increase the synthesis of fibroblasts and collagen fibers. Therefore, it is effective for treatment of damaged ligament and ligament reconstruction.
(2) The transplantation and transplantation reconstruction treatment using the bone graft material containing the ligament cells of the tendon are carried out by treating the transplantation site with ultrasonic vibration singly or alternately with high-frequency heat, It can be used to make good living and to be kept constant.
FIG. 1 is a block diagram illustrating an apparatus for treating tendon ligaments using ultrasonic vibration according to a preferred embodiment of the present invention.
FIG. 2 is a schematic view showing a home type of a tendon treatment apparatus using ultrasonic vibration according to a preferred embodiment of the present invention.
FIG. 3 is a schematic view showing a hospital form of a tendon treatment apparatus using ultrasonic vibration according to a preferred embodiment of the present invention.
FIGS. 4A and 4B are cell enlargement images when ultrasonic vibrations of various frequency bands are not transmitted or transmitted to the extracted tendinous tissue tissue. FIG.
DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS Hereinafter, preferred embodiments of the present invention will be described in detail with reference to the accompanying drawings. In the following description, a detailed description of known functions and configurations incorporated herein will be omitted when it may obscure the subject matter of the present invention.
The same reference numerals are used for portions having similar functions and functions throughout the drawings.
In addition, in the entire specification, when a part is referred to as being 'connected' to another part, it may be referred to as 'indirectly connected' not only with 'directly connected' . Also, to include an element does not exclude other elements unless specifically stated otherwise, but may also include other elements.
As shown in FIG. 1 to FIG. 3, the apparatus 100 for treating ligamentous tendon using ultrasonic vibration according to a preferred embodiment of the present invention is designed to treat an injured tendon that is torn or overturned by an external impact or an external force, An ultrasonic vibration generator 120 and a controller 130 so as to increase the growth or activity of the fibroblast that synthesizes collagen fibers related to the ligament.
The contact portion 110 is a contact member directly contacting the body skin corresponding to the damaged part of the tendon of the body to be treated.
The contact portion 110 is electrically connected to the body portion 101 in which the ultrasonic vibration generating portion 120 and the controller 130 are installed through a power cable C having a predetermined length, However, the present invention is not limited thereto, and it may be provided in various forms such as a belt type, an attachable type, a flat type, and a curved type so as to suitably adhere to the skin according to a body part.
The contact unit 110 may include an oscillator, which is an output unit that receives the ultrasonic electric signal having a frequency range of 20 kHz or more and generates vibration.
The ultrasonic vibration generator 120 generates a predetermined ultrasonic electric signal so as to transmit the vibration at the shortest distance to the injury site of the tendon of the skin through the skin contacting the contact part 110. The generated electric signal is transmitted through a cable And is transmitted to the oscillator of the contact portion to generate ultrasonic vibration.
At this time, the sonic vibration transmitted to the injured tendon region through the contact portion 110 has a specific sound band frequency in a frequency region of 20 kHz or more. The vibration is directly transmitted to the damaged region associated with the tendon ligament through the skin, To stimulate the growth or activity of fibroblasts that synthesize collagen fibers associated with the tendon, and to regulate their growth or activity.
The controller 130 adjusts the intensity of the ultrasonic vibration generated in the ultrasonic vibration generator according to the location of the injured ligament of the tendon, which is spaced apart from the contact portion.
In other words, the method of growing and activating the fibroblast associated with injured tendon ligaments increases the amount of cell migration and extracellular secretion by transmitting ultrasonic vibration of 20 kHz or more to the damaged tendon ligament region, and the collagen fiber synthesis is activated, Reconstruction, rehabilitation after ligament surgery, manufacture of living body materials, and reconstruction after transplantation.
The ultrasonic vibration generator may include a variable frequency oscillator and an originating amplifier, wherein the variable frequency oscillator generates a frequency of 20 kHz or more, and the originating amplifier amplifies a frequency generated by the variable frequency oscillator.
That is, the ultrasonic vibrations generated in the variable frequency oscillator are amplified in the originating amplifier to prevent attenuation of the injured ligament before it is passed through the damaged tendon, and then the frequency passed through the originating amplifier is transmitted to the injured tendon to be excited.
A high frequency generator for generating a high frequency to transmit the high frequency wave to the damage site of the tendon through the skin selectively contacting the contact area and providing the ultrasonic vibration through the skin contacting the contact part, (140).
The high-frequency generating unit 140 is electrically connected to the contact unit 110 through a power cable C. The high-frequency generating unit 140 receives a high-frequency signal set in the contact unit 110 to generate a high- And the high frequency output unit can be disposed in the contact portion 110 together with the ultrasonic output unit.
The body part 101 includes an input part 131 for inputting data and data necessary for generating ultrasonic waves for treating a damaged tendon ligament, an output part 132 for displaying and monitoring the generated sound wave vibration as a numerical value or an image, And an on-off switch 135 for applying external power.
As shown in FIG. 2, the main body 101 can be realized by a home-use tendon treatment apparatus 100 designed to be miniaturized in its entire volume and size for easy handling and use, or as shown in FIG. 3, The total volume and the size of the patient can be increased by a relatively large film-designed hospital gun ligament healing apparatus 100a so as to add additional functions, and the gun ligament healing apparatus 100a designed for the hospital can be handled and transported A separate handle H can be additionally designed to facilitate the operation.
The controller 130 adjusts the intensity of the high frequency generated by the high frequency generator 140 according to the position of the damaged region of the tendon ligament that is separated from the contact portion 110, And can control the high-frequency heat transmitted to the injury site of the ligament.
The control unit generates a predetermined high frequency band signal when the AC power input from the external power source is reduced and converted to DC power to supply power to the high frequency generating unit, and the generated high frequency band signal is converted into high frequency It is transmitted to the heat output unit to generate a high frequency heat and the generated high frequency heat is transmitted to the damaged tendon through the skin to increase the amount of the cell movement and the secretion of the extracellular matrix as well as the ultrasonic vibration and the synthesis of the collagen fiber is activated Reconstruction of ligaments, rehabilitation after ligament surgery, manufacture of biomaterials, and reconstruction after transplantation.
< Preparation Example > Preparation of experimental gun ligament cells
The surgical ligaments of the animals (rats) were treated by surgical procedure with 200 μl of Antibiotic / Antimycotic, 10 μl of Gentamycin and 10 μl of Dulbecco's Modified Eagle Medium containing 10% fetal bovine serum (FBS) It was stored in the icebox and transported to the laboratory within a short period of time.
The extracted tendon tissues were put into 3 ml of 1000 U collagenase solution and stirred in a CO2 incubator maintained at 37 ° C for 60 minutes to loosen the cell-tissue lumen. The tissues and the enzymes were all collected, and DMEM containing 10% FBS And the supernatant was discarded. The remaining cell pellet was resuspended in 6 well-plates (surface area 10 cm 2) containing 2 ml of DMEM medium containing 10% (v / v) FBS ) And cultured for 10 days in a CO2 incubator maintained at 37 캜 while changing the medium every 3 days.
< Example  1> Ultrasonic vibration This Ligamentous  Influence on Growth
After the primary culture as in Preparation Example 1, the medium was removed and the cells adhered to the bottom of the 6 well plate were washed once with 200 μl of antibiotics / antifungal agent and 2 ml of PBS (Phosphate Buffered Saline) containing 10 μl of gentamicin And washed.
The washed cells were treated with 0.5 ml of 0.05% (w / v) trypsin and 0.01% (w / v) EDTA in PBS solution and treated at 37 ° C for 5 minutes to allow the cells to float on the bottom of the plate to float in the solution. The plate cell solution was mixed with 15 ml of DMEM medium containing 10% (v / v) FBS and centrifuged at 1,000 rpm for 5 minutes to recover only the cells.
The cells were inoculated in a 6-well plate containing 2 ml of DMEM medium containing 10% (v / v) FBS at a concentration of 2 × 10 4 cells / ml, and the medium maintained at 37 ° C. 2 &lt; / RTI &gt; incubator for 10 days.
At this time, an ultrasonic vibration generator for generating an ultrasonic vibration of 20 kHz or more was attached to the incubator, and the 6-well plate was placed on the ultrasonic vibration generator. Then, a frequency of 0 Hz (control group), 10 kHz and 20 kHz And cultured while delivering ultrasonic vibration. After the incubation was completed, the medium was removed and the cells attached to the bottom of the 6 well plate were washed once with 200 μl of antibiotic / antifungal agent and 10 μl of PBS containing 10 μl of gentamicin.
After washing, 2 ml of 0.05% (w / v) trypsin and 0.01% (w / v) EDTA in PBS solution was added to the cells attached to the bottom of the 6 well plate and the cells were treated at 37 ° C for 5 minutes to suspend . The plate cell solution was added to 15 ml of DMEM medium containing 10% (v / v) FBS and centrifuged at 1000 rpm for 5 minutes.
After centrifugation, the supernatant was discarded. 10 ml of DMEM medium containing 10% (v / v) FBS was added to the recovered cell pellet, and pipetting was performed for about 5 minutes to separate the cells.
As a result, as shown in FIG. 4A and FIG. 4B, it can be seen that in the experimental group treated with ultrasonic vibration having frequencies of 10 kHz and 20 kHz on the basis of the control group (0 Hz) The density of the cells was increased.
Thus, it was confirmed from the above results that treatment of the tumor ligament cells with ultrasonic vibration having a frequency of 20 kHz promotes cell growth of the tendon ligament.
&Lt; Example 2 >
It was confirmed that when high frequency heat is delivered to the injured ligament, the growth of tendon ligament is promoted by ultrasonic vibration.
&Lt; Example 3 >
It was confirmed that the combined delivery of the ultrasonic vibration and the radiofrequency heat in the damaged ligament ligament region were accelerated and accelerated relative to the cell growth of the ligament due to the independent ultrasonic vibration.
<Example 4>
On the other hand, it was confirmed that the production of trypsin or chymotrypsin, which is an anti-inflammatory protease effective for reducing the inflammatory reaction caused by damage to the tendon ligament, is increased, thereby promoting the growth of tendon ligament.
&Lt; Example 5 >
In addition, it was confirmed that the amount of zinc which is necessary for the growth and development of the fibroblast associated with the tendon ligament and which plays the most important role in stabilizing the structure of the protein and the cell membrane is increased, thereby promoting the growth of the tendon ligament .
It will be apparent to those skilled in the art that various modifications and variations can be made in the present invention without departing from the spirit or scope of the inventions. It will be apparent to those of ordinary skill in the art.
110:
120: Ultrasonic vibration generator
130:
140:

Claims (3)

  1. A contact portion in which the tendon ligament is brought into close contact with a corresponding portion of the body skin;
    An ultrasonic vibration generator for generating a sound wave to transmit a vibration at a shortest distance to a damaged part of the tendon through the skin in contact with the contact part;
    A controller for adjusting the intensity of the ultrasonic vibration generated in the ultrasonic vibration generator according to the position of the damage site of the tendon ligature separated from the contact portion; Including
    Wherein the growth or activity of fibroblasts synthesizing collagen fibers associated with the tendon is increased.
  2. The method according to claim 1,
    And a high-frequency generating unit for generating a high-frequency wave so as to transmit the high-frequency heat at the shortest distance to the injured ligament of the tendon through the skin in contact with the contact unit,
    Wherein the controller adjusts intensity of a high frequency generated in the high frequency generator according to a position of a damaged region of the tendon ligament that is spaced apart from the contact portion.
  3. 3. The method of claim 2,
    Wherein the control unit controls the ultrasonic vibration and the high frequency heat transmitted to the injury site of the tendon through the skin contacting the contact unit to be alternately generated at a predetermined period of time.
KR1020150146306A 2015-10-20 2015-10-20 Device for Curing the ligament tendon using a Ultrasonic Waves Vibration KR20170046027A (en)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100537343B1 (en) * 2004-10-01 2005-12-19 주식회사 듀플로젠 An ultrasonic equipment for treatment of osteoarthritis
KR101415797B1 (en) * 2012-09-18 2014-07-08 (주)혜민 Ultrasound pad for physical therapy
KR20140117860A (en) * 2013-03-27 2014-10-08 (주)아마오리엔트 Skin treatment apparatus using ultrasound and radio frequency and control method thereof
KR20150105065A (en) * 2014-03-07 2015-09-16 김상도 High-Fequency Therapeutic Apparatus for losing weight and muscle pain

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100537343B1 (en) * 2004-10-01 2005-12-19 주식회사 듀플로젠 An ultrasonic equipment for treatment of osteoarthritis
KR101415797B1 (en) * 2012-09-18 2014-07-08 (주)혜민 Ultrasound pad for physical therapy
KR20140117860A (en) * 2013-03-27 2014-10-08 (주)아마오리엔트 Skin treatment apparatus using ultrasound and radio frequency and control method thereof
KR20150105065A (en) * 2014-03-07 2015-09-16 김상도 High-Fequency Therapeutic Apparatus for losing weight and muscle pain

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