KR20170000171A - Composition for mask pack comprising precious metal nanoparticles and manufacturing the same - Google Patents
Composition for mask pack comprising precious metal nanoparticles and manufacturing the same Download PDFInfo
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- KR20170000171A KR20170000171A KR1020150089029A KR20150089029A KR20170000171A KR 20170000171 A KR20170000171 A KR 20170000171A KR 1020150089029 A KR1020150089029 A KR 1020150089029A KR 20150089029 A KR20150089029 A KR 20150089029A KR 20170000171 A KR20170000171 A KR 20170000171A
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- niacinamide
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/673—Vitamin B group
- A61K8/675—Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0212—Face masks
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/41—Particular ingredients further characterized by their size
- A61K2800/413—Nanosized, i.e. having sizes below 100 nm
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
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- Cosmetics (AREA)
Abstract
The present invention relates to a cosmetic mask pack composition for skin care which is effective for skin care by mixing gold, platinum or silver nanoparticles and niacinamide with an amino acid composition, a humectant such as glycerin, (b) a step of evacuating the vacuum deposition chamber using a vacuum pump to perform a vacuum deposition process, (c) a step of vacuum-depositing the niacinamide powder in the step (D) generating noble metal as nano-sized evaporation particles by using an evaporation source provided in the vacuum deposition chamber; and (e) heating the niacin amide powder And evaporating the evaporated particles, thereby providing an effect of improving skin elasticity and wrinkles The can.
Description
The present invention relates to a skin-care mask pack composition containing noble metal nanoparticles and a method for producing the same. More particularly, the present invention relates to a skin-beauty mask pack composition containing noble metal nanoparticles, Skin cosmetic mask pack composition and method for producing the same.
Ozone depletion due to serious air pollution these days, if too much harmful ultraviolet rays, it is easy to get skin cancer, skin aging, function of various organs of the body is deteriorated and it is easy to catch various diseases. The skin of the human body is badly affected by the air pollution and the dry air. Especially, the faces and hands which are always exposed to the air are directly affected by the air compared to other places. Thus, the face progresses faster than other parts of the body.
Exposure to excessive ultraviolet rays or pollutants causes skin irritation such as erythema, edema, itching, and inflammatory reaction. These skin troubles are not only cosmetic problems, but also substances that are produced during the inflammatory process are accompanied by secondary pigmentation, promoting the collapse of skin elastic fibers and increasing skin wrinkles. Skin tissue is exposed to chemical substances such as medicines, food additives, residual pesticides, etc. in everyday life including ultraviolet rays, so that excessive active oxygen is always produced.
It has been known that it gradually becomes defensive ability since the age of the elderly, and eventually it causes aging due to damage of the skin tissue, lipid peroxy, and the like. In particular, protein molecules constituting a singlet oxygen skin are excited to generate free radicals when they are exposed to ultraviolet rays. Their life span is as short as a millionth of a second, but they damage skin and cause skin cancer. . Thus, the prevention or delay of aging of the skin may be possible by eliminating free radicals in the skin.
Of course, there are superoxide dismutase (SOD), catalase, vitamin E, vitamin C, and uviquinol, which are antioxidants (free radical scavengers) in the human body. But gradually, the antioxidant system begins to break down by age, pollution, ultraviolet rays, stress and so on. Therefore, the antioxidant system is neutralized and free radicals are gradually increased.
This increased free radical destroys collagen (collagen), elastin, and hyaluronic acid, which are connective tissues of the dermis, causing settlement (wrinkling) of the skin in certain areas of the skin and oxidizing the lipid part of the cell membrane, It causes destruction and causes diseases such as dermatitis, acne and skin cancer. In addition, this free radical participates in a spontaneous oxidation reaction (dopaquinone melanin) during the melanin formation process, and causes the causes such as spots and freckles and wrinkles.
As a method of skin care, there is an increasing demand for packs.
A pack is a box filled with active substances in the sense of "filled box or wrapped", and it is wrapped around the face to clean the dirt of the pores and effectively supply moisture and cosmetic ingredients to the skin. To restore the skin's physiological function is a kind of functional cosmetics. Since the pack can effectively provide various nutrients to the skin, various effects such as moisturizing, soothing, aging, keratin and waste removal, tired skin recovery, elasticity enhancement and whitening can be expected by these cosmetic ingredients.
Skin care mask packs include peel-off type, which is a general method of applying a thin sheet of vegetables or fruits to the face, in addition to applying a transparent or semi-transparent gel pack material to remove the film formed on the skin after drying, A nonwoven fabric type pack for attaching the nonwoven fabric absorbing the material to the face, and a wash off type for washing with water after drying such as clay or jelly type.
There is a disadvantage of sticking a thin plate of vegetable or fruit one by one and a drawback that it moves when it is moved. The peel-off type is troublesome to take off one by one over time and the nonwoven type infiltrates the essence and the lotion There is a limit to the amount of cosmetic materials absorbed by the fibers, and there is the inconvenience of flowing down when absorbing a large amount. The wash-off type using loess or clay is troublesome to wash after drying, and inconveniences such as muddy water entering the eyes or clothes.
The conditions required for general skin beauty mask packs should be easy to apply with appropriate viscosity at the time of use, be easily peeled at the same time while giving tension to the skin while drying in a proper time, and keep a soft and moist texture after use.
Mud packs, fruit packs, herbal medicine packs, and ocher packs, which are used by many women, are used for facial and body skin. Skin cosmetics The constituents and efficacy of a mask pack can be absorbed through the skin and affect the cellular structure of the skin.
This is an obvious fact. However, in a conventional beauty pack, it is often impossible to completely satisfy the pure functional aspects of such a pack.
Preservatives are formulated in cosmetics and used for the purpose of preventing the growth of products by inhibiting the growth of microorganisms that pollute the cosmetics from the outside. When preservatives are not added, aseptic manufacturing process is required to secure buoyancy, Or the use period is limited, or the container is made specially, and the tendency to lack economical versatility is increased.
A product which can be applied on the face by adding a chemical preservative for cosmetic use such as methyl paraben as a commonly used preservative has been developed. However, this is merely an improvement with emphasis on convenience, and since natural preservative materials such as silver (Ag) produced by a physical method using a target are not used, freshness unique to a natural material can be expected In addition, there is a problem that skin damage can be caused by causing allergy to the human body through the use of chemicals.
One example of the technique for solving such a problem is described in Documents 1 and 2 below.
For example, in the following Patent Document 1, 45 ml of butylene glycol and 5.0 g of lecithin are added to a mixer, 48 g and 2 g of ceramide and adenosine are added as active ingredients at a weight ratio of 96: 4, respectively, , And the obtained composition was spray-dried by a nozzle type spray drier to prepare a granular core having a particle size of 850 탆. The core was coated with gold using physical vapor deposition (PVD) A process for producing gold-coated particles for producing gold-coated particles and a cosmetic composition containing the same.
In addition, Patent Document 2 discloses a vacuum deposition chamber, a stirring vessel provided in the vacuum deposition chamber, a screw provided in the stirring vessel and stirring the carrier, and a steam particle provided on the stirring vessel in the vacuum deposition chamber, Comprising the steps of: introducing an inert gas into the vacuum deposition chamber so that the degree of vacuum of the vacuum deposition chamber is 10 -4 to 1 torr; The method comprising the steps of: generating steam particles for forming nanoparticles; stirring the carrier by controlling the speed of the screw to 1 to 200 rpm; and depositing vapor particles on the carrier to form nanoparticles Discloses a method for manufacturing a nano powder attached to a carrier.
Patent Document 3 further discloses that sodium stearoyl glutamate; Fatty alcohol; A polyol which is hydrogenated glycerin or dipropylene glycol; Higher fatty acids; ethanol; 0.1 to 1.0: 0.1 to 0.5: 3.0 to 10.0: 0.2 to 0.5: 1.0, respectively, of an oil selected from the group consisting of squalane, octyldodecyl myristate, octyl palmitate, cyclomethicone and dimethicone; To 2.0: 0.5 to 2.0, and 0.1 to 10% by weight of niacinamide is contained in the nano emulsion. 60 to 100% of the alkyl group of the higher fatty alcohol is a stearoyl carbon chain , 90% or more and 100% or less of the alkyl group of the higher fatty acid is disclosed for a niacinamide containing niacinamide, which is a stearoyl carbon chain.
However, in the conventional art as described above, the mask pack to which niacinamide is applied has a disadvantage that it only has an effect of reducing the moisture loss of the epidermis and improving the lipid content, and is not provided with antibacterial and germicidal functions.
In addition, in the above conventional techniques, there is a problem that the use of the mask pack can not promote blood circulation and activate the skin.
Disclosure of the Invention The object of the present invention is to solve the above-mentioned problems, and an object of the present invention is to provide a skin care mask pack composition containing noble metal nanoparticles capable of performing an antibacterial and sterilizing function by using a mask pack, And a method for manufacturing the same.
Another object of the present invention is to provide a skin beauty mask pack composition containing noble metal nanoparticles capable of promoting blood circulation and skin activation action, and a method for producing the same.
In order to accomplish the above object, the present invention provides a method for preparing a skin-beauty mask pack composition containing noble metal nanoparticles, comprising the steps of: (a) mixing niacinamide powder in a vacuum deposition chamber (B) vacuum-exhausting the inside of the vacuum deposition chamber using a vacuum pump to perform a vacuum deposition process; (c) stirring the niacinamide powder added to the stirring tank in the step (a) (D) generating a noble metal as nano-sized evaporation particles by using an evaporation source provided in the vacuum deposition chamber, and (e) depositing the evaporation particles on the niacinamide powder .
In the method for manufacturing a skin-care mask pack composition according to the present invention, the step (c) is characterized in that it is stirred at a rate of 0.1 to 400 rpm by the stirring blade.
In the method of manufacturing a skin care mask pack composition according to the present invention, the step (b) is performed at a working pressure of 5 × 10 -4 to 5 × 10 -3 torr.
In the method of manufacturing the skin care mask pack composition according to the present invention, the step (d) may be performed by a method including thermal evaporation, electron beam evaporation (E-beam evaporation), DC sputtering (DC sputtering), cathodic arc evaporation sputtering, DC magnetron sputtering, RF sputtering, ion beam sputtering, Molecular Beam Epitaxy, arc discharge process, laser ablation, (Laser ablation).
In the method for manufacturing a skin and cosmetic mask pack composition according to the present invention, evaporation of the evaporation particles is carried out at a size of 1 to 100 nm, and the noble metal is any one of silver, gold and platinum.
In order to achieve the above object, the skin care mask pack according to the present invention is characterized in that it is manufactured by the method for manufacturing a skin care mask pack composition as described above.
As described above, according to the skin beauty mask pack composition containing noble metal nanoparticles according to the present invention and the method for producing the same, by using a mask pack to which silver / niacinamide, gold / niacinamide, and platinum / It is possible to remarkably improve the effect of skin elasticity and wrinkle improvement along with freckle removal, anti-cancer and moisturizing effect.
According to the skin beauty mask pack composition containing the noble metal nanoparticles according to the present invention and the method for producing the same, nanoparticles of noble metals such as silver, gold, and platinum can be easily formed, and nano- An effect of being easily combined can be obtained.
1 is a schematic view of a vacuum deposition apparatus for manufacturing a skin-care mask pack composition containing noble metal nanoparticles according to the present invention,
FIG. 2 is a process chart for manufacturing a skin beauty mask pack containing noble metal nanoparticles according to the present invention. FIG.
These and other objects and novel features of the present invention will become more apparent from the description of the present specification and the accompanying drawings.
First, the outline of the present invention will be described.
The inventors of the present invention prepared a nano-sized silver (Ag) / niacinamide made by the NPP method in consideration of the active surface of the skin-care mask pack composition for skin tissue, Natural antiseptics and nano-sized gold (Au) / niacinamide or platinum (Pt) / niacinamide to produce antioxidant substances with excellent cytoprotective effect, which are mixed with amino acid compositions, moisturizers, Skin mask pack composition was prepared.
The NPP method refers to a process in which nanoparticles are formed on the surface of a carrier while stirring a carrier powder or a carrier chip.
Niacinamide, which is applied to the mask pack composition of the present invention, is a water-soluble vitamin B3, also known as nicotinamide, which is a type of niacin, a vitamin B group.
This niacinamide, together with ceramide, promotes the synthesis of cholesterol and fatty acid necessary for the formation of lamellar structure simultaneously, thereby reducing the moisture loss of the epidermis and improving the fat mass. These niacin amides are essential to our bodies and are also included in foods such as green vegetables and cereals. The need for niacinamide for healthy skin has been recognized since the early 20th century. When vitamin B3 is lacking in the diet, pellagra, a serious skin lesion, has appeared, and niacinamide has been known as a vitamin to prevent it.
In addition, the mask pack composition of the present invention may further comprise a skin cosmetic ingredient as an active ingredient for use as a cosmetic composition.
The skin cosmetic ingredient may be a material having a function of skin elasticity, moisturizing, whitening, antioxidation, wrinkle improvement, anti-aging etc. which are conventionally used in the production of a cosmetic composition. Examples thereof include niacinamide, adenosine, sodium hyaluronate Histidine, threonine, serine, glutamic acid, proline, glycine, valine, glyceryl ligninolate, glyceryl arachidonate, natural extract and the like can be used as a kind of nate, ubiquinone, alanine and amino acid.
The natural extract may be extracted from mushroom, guava leaf, rose flower, green tea, golden root, bokbunja, white papule (roots of gherkin), lotus flower, bark bark (rootbark of mulberry). In addition, the mask pack composition of the present invention may further contain a moisturizing agent, a thickening agent, a surfactant, an emulsifying stabilizer, a preservative, an essential amino acid, a fragrance, and the like as a constituent component that is conventionally used for maintaining basic physical properties and quality for use as a cosmetic composition .
Examples of the moisturizing agent include butyleneglycol, fructan, and glycerin.
The thickener may be xanthan gum, hydroxyethyl methacrylate / sodium acryloyldimethyltaurate copolymer, or the like.
The surfactant acts as an emulsifier or solubilizer, and is also used for adjusting viscosity of the mask pack composition or improving viscosity stability. The surfactant to be used may be any of a cationic surfactant, a positive surfactant and a nonionic surfactant.
The preservative may be selected from the group consisting of, for example, 1,2-hexanediol and noble metals such as silver, gold and platinum.
The silver nanoparticles have antibacterial and germicidal functions and are effective for inflammatory skin and have been used as a substitute for preservatives for a long time. Therefore, they are suitable as parabens free (paraben) natural preservatives.
The gold nanoparticles have anti-wrinkle, freckle removal, anti-cancer and moisturizing effects due to blood circulation promotion and skin activation action.
The platinum nanoparticle maintains skin elasticity and acts as a skin activating agent to catch skin troubles, and has antioxidant effect to prevent aging. Particularly, in case of platinum, when it comes into contact with the skin, it exhibits a strong catalytic function to the skin, thereby activating the alternating action of the positive and negative electrons of the human body to activate the metabolism and purifying the blood, ultimately bringing about an antibacterial effect and anti- It is possible to make it possible.
Example
The mask pack is prepared by a conventional method from the following components.
Components are melted by heating to 50 DEG C with stirring while blending the components of phase A using a suitable mixer.
Separately, the C phase components are blended with a suitable mixer and heated with mixing to dissolve the C phase components.
The components of the B phase are mixed with hydroxyethyl methacrylate / sodium acryloyldimethyltaurate copolymer while the xanthan gum is stirred. The mixture is evenly dispersed and wetted without tangling. Inserting purified water thereafter will not tangle and shorten the manufacturing time.
Extract of D phase, extract of mackerel, extract of guava, rose flower, green tea extract, golden root, extract of bokbunja, white bark extract, lotus bark extract, and mulberry bark extract are blended in a mixer and mixed with 1,2hexanediol .
In the present invention, the average particle size of silver, gold, and platinum nanoparticles is made to several nanometers, and noble metal nanoparticles are formed on the surface of the niacinamide powder by physical vacuum vapor deposition to form silver / niacinamide, gold / / Niacinamide was prepared.
The physical vacuum deposition process is performed in a vacuum deposition apparatus having a vacuum deposition chamber and an evaporation source as shown in FIG.
1 is a schematic view of a vacuum deposition apparatus used for forming nano-sized noble metal particles on the surface of a niacinamide powder according to the present invention.
The vacuum deposition apparatus shown in FIG. 1 includes a
The niacinamide powder to be used in the present invention is introduced into the stirring
The shape of the stirring
A
As shown in FIG. 1, the
Next, the production of the skin-care mask pack composition according to the present invention will be described with reference to FIG.
2 is a process diagram for manufacturing a skin beauty mask pack containing noble metal nanoparticles according to the present invention.
The skin-beauty mask pack according to the present invention is a skin-beauty mask pack containing noble metal nanoparticles. In the composition to be applied to the pack, first, niacinamide powder is put into a
Further, in order to perform the vacuum deposition process, the inside of the
The working pressure of the
In step S10, the niacinamide powder injected into the stirring
In the step S30, the stirring
Next, the noble metal is generated as nano-sized evaporation particles by using the
Thereafter, the evaporated particles are deposited on the niacinamide powder (S50).
The deposition of the evaporation particles on the niacinamide powder in the step S50 is performed by depositing the noble metal particles on the niacinamide powder to form nuclei and then forming the nano-sized noble metal particles by further deposition of the noble metal particles A step of forming nano-sized noble metal particles by depositing noble metal particles on a new niacin amide powder phase in which niacinamide powder is stirred, rotated and mixed, or in a niacinamide powder phase in which noble metal particles are not deposited, or in a niacinamide powder phase where noble metal particles are not deposited .
Preferably, in step S50, the evaporated particles are deposited on the niacinamide powder to a thickness of 1 to 10 mu m per minute per minute.
The size of the noble metal particles formed on the niacinamide powder is preferably 1 to 100 nm.
Next, as described above, the mask pack composition produced according to the present invention is injected into a tencel sheet made of an eco-friendly material (S60), cut into a shape of a face contour (S70), and the mask pack is completed.
The mask pack composition of the present invention may contain components other than the above-mentioned components, such as an oily component, a polyhydric alcohol, a sugar, a preservative, a stabilizer, a pH adjuster, a vitamin, an antioxidant, an ultraviolet absorber, And may further contain any one of additives.
As described above, the skin elasticity and wrinkle improvement test were performed using the mask pack to which gold / niacinamide manufactured according to the present invention was applied and the mask pack to which only niacinamide was applied as a comparative example.
Twenty women aged 20 to 60 years and 20 men aged 20 to 60 years living in Seoul were divided into two groups, one for the mask pack according to the present invention and the other for four weeks once a week for the comparative example The survey was conducted. The questionnaire was designed to record normal, excellent, and excellent results on the effects of skin elasticity and wrinkle improvement before and after use of the mask pack. The results are shown in Table 1 below.
As can be seen from the above table, in the case of the mask pack to which the gold / niacinamide according to the present invention was applied, the effect of skin elasticity and wrinkle improvement was remarkably improved over the mask pack made of only niacinamide, .
Although the present invention has been described in detail with reference to the above embodiments, it is needless to say that the present invention is not limited to the above-described embodiments, and various modifications may be made without departing from the spirit of the present invention.
By using the skin-care mask pack composition containing noble metal nanoparticles according to the present invention and the manufacturing method thereof, the effect of skin elasticity and wrinkle improvement can be greatly improved.
100: Vacuum deposition chamber
110: stirring tank
120: stirring blade
130: Rotary motor
140: Shutter
150: evaporation source
160: Vacuum exhaust system
170: Inert gas supply part
Claims (6)
(a) introducing niacinamide powder into a stirring vessel in a vacuum deposition chamber,
(b) evacuating the vacuum deposition chamber using a vacuum pump to perform a vacuum deposition process,
(c) stirring the niacinamide powder injected into the stirring tank in the step (a) with a stirring blade,
(d) generating noble metal as nano-sized evaporation particles using an evaporation source provided in the vacuum deposition chamber, and
(e) depositing the evaporation particles on the niacinamide powder. < RTI ID = 0.0 > 8. < / RTI >
Wherein the step (c) is stirred at a rate of 0.1 to 400 rpm by the stirring blade.
Wherein the step (b) is performed at a working pressure of 5 x 10 -4 to 5 x 10 -3 torr.
The step (d) may be performed by a thermal evaporation method, an E-beam evaporation method, a DC sputtering method, a cathodic arc sputtering method, a DC magnetron sputtering method, an RF sputtering method Characterized by being performed by any one of RF sputtering, ion beam sputtering, Molecular Beam Epitaxy, arc discharge process, and laser ablation. A method for manufacturing a skin cosmetic mask pack composition.
The evaporation of the evaporation particles is performed in a size of 1 to 100 nm,
Wherein the noble metal is any one of silver, gold, and platinum.
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| KR1020150089029A KR20170000171A (en) | 2015-06-23 | 2015-06-23 | Composition for mask pack comprising precious metal nanoparticles and manufacturing the same |
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| KR1020150089029A KR20170000171A (en) | 2015-06-23 | 2015-06-23 | Composition for mask pack comprising precious metal nanoparticles and manufacturing the same |
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Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20190094116A (en) * | 2018-02-02 | 2019-08-12 | 고석근 | Manufacturing process of nono-particles using flowable substrates and manufacturing device therefor |
| KR20210034292A (en) * | 2019-09-20 | 2021-03-30 | 플람 주식회사 | A portable apparatus for treating the mask pack with plasma |
| KR102255431B1 (en) * | 2021-03-23 | 2021-05-24 | 주식회사 성진프린텍 | Microcurrent mask pack including platinum nano |
| KR102310736B1 (en) * | 2021-05-03 | 2021-10-08 | (주)쥬넥스 | Manufacturing method of gold nano particles |
| KR102360781B1 (en) * | 2021-09-30 | 2022-02-14 | (주)쥬넥스 | Hydrocolloid Patch For Alleviating Skin Inflammation |
| KR102445954B1 (en) * | 2021-09-30 | 2022-09-22 | 주식회사 에이유랩스 | Manufacturing Method of Composition For Wrinkle Reduction Comprising Niacinamide Deposited With Gold Nanoparticle |
| KR102445952B1 (en) * | 2021-09-30 | 2022-09-22 | 주식회사 에이유랩스 | Manufacturing Method of Antioxidant Composition Comprising Niacinamide Deposited With Gold Nanoparticle |
| KR102445951B1 (en) * | 2021-09-30 | 2022-09-22 | 주식회사 에이유랩스 | Manufacturing Method of Emulsion Composition Comprising Niacinamide Deposited With Gold Nanoparticle |
| KR102445953B1 (en) * | 2021-09-30 | 2022-09-22 | 주식회사 에이유랩스 | Manufacturing Method of Composition For Wrinkle Reduction Comprising Niacinamide Deposited With Gold Nanoparticle |
| KR102445955B1 (en) * | 2021-09-30 | 2022-09-22 | 주식회사 에이유랩스 | Manufacturing Method of Composition For Skin Regeneration Comprising Niacinamide Deposited With Gold Nanoparticle |
| WO2023200235A1 (en) * | 2022-04-14 | 2023-10-19 | 주식회사 에이유랩스 | Method for preparing niacinamide powder containing gold particles |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| KR20190094116A (en) * | 2018-02-02 | 2019-08-12 | 고석근 | Manufacturing process of nono-particles using flowable substrates and manufacturing device therefor |
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| KR102310736B1 (en) * | 2021-05-03 | 2021-10-08 | (주)쥬넥스 | Manufacturing method of gold nano particles |
| EP4134187A4 (en) * | 2021-05-03 | 2024-05-15 | Jeunex Co., Ltd. | Gold nanoparticle preparation method |
| JP2023528199A (en) * | 2021-05-03 | 2023-07-04 | チュネックス カンパニー リミテッド | Method for producing gold nanoparticles |
| US20230182206A1 (en) * | 2021-05-03 | 2023-06-15 | Jeunex Co., Ltd. | Gold nanoparticle manufacturing method |
| CN115568283A (en) * | 2021-05-03 | 2023-01-03 | 株式会社乔奈斯 | Method for manufacturing gold nanoparticles |
| KR102360781B1 (en) * | 2021-09-30 | 2022-02-14 | (주)쥬넥스 | Hydrocolloid Patch For Alleviating Skin Inflammation |
| KR102445955B1 (en) * | 2021-09-30 | 2022-09-22 | 주식회사 에이유랩스 | Manufacturing Method of Composition For Skin Regeneration Comprising Niacinamide Deposited With Gold Nanoparticle |
| KR102445953B1 (en) * | 2021-09-30 | 2022-09-22 | 주식회사 에이유랩스 | Manufacturing Method of Composition For Wrinkle Reduction Comprising Niacinamide Deposited With Gold Nanoparticle |
| KR102445951B1 (en) * | 2021-09-30 | 2022-09-22 | 주식회사 에이유랩스 | Manufacturing Method of Emulsion Composition Comprising Niacinamide Deposited With Gold Nanoparticle |
| KR102445952B1 (en) * | 2021-09-30 | 2022-09-22 | 주식회사 에이유랩스 | Manufacturing Method of Antioxidant Composition Comprising Niacinamide Deposited With Gold Nanoparticle |
| KR102445954B1 (en) * | 2021-09-30 | 2022-09-22 | 주식회사 에이유랩스 | Manufacturing Method of Composition For Wrinkle Reduction Comprising Niacinamide Deposited With Gold Nanoparticle |
| WO2023200235A1 (en) * | 2022-04-14 | 2023-10-19 | 주식회사 에이유랩스 | Method for preparing niacinamide powder containing gold particles |
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