KR20160136982A

KR20160136982A - Composition for Hair growth promotion and Hair loss prevention and Manufacturing Method thereof

Info

Publication number: KR20160136982A
Application number: KR1020150071415A
Authority: KR
Inventors: 이건목; 김영철
Original assignee: 이건목; 김영철
Priority date: 2015-05-22
Filing date: 2015-05-22
Publication date: 2016-11-30
Also published as: KR101752232B1

Abstract

The present invention relates to a composition for preventing hair loss and promoting hair growth and a method for preparing the same, wherein the composition for preventing hair loss and promoting hair growth comprises 1 part by weight of a red ginseng concentrate having a solid content of 40 to 60% 10 to 20 parts by weight of Sasao, 10 to 20 parts by weight of Ganoderma lucidum, 10 to 20 parts by weight of Ganoderma lucidum, 5 to 15 parts by weight of dried ginger, 5 to 10 parts by weight of Ganoderma lucidum, 5 to 10 parts by weight of licorice and 1 to 5 parts by weight of licorice 4 to 5 parts by weight of a concentrated concentrate of the first group of natural medicines having a solid content of 40 to 60% 15 to 30 parts by weight of persimmon, 15 to 30 parts by weight of persimmon, 15 to 20 parts by weight of persimmon, 5 to 10 parts by weight of a lateral leaf, 5 to 10 parts by weight of a ginkgo leaf, and 5 to 10 parts by weight of a bottle, And 2 to 5 parts by weight of a second group of natural agent concentrates. Thus, hair loss prevention and hair growth promoting effect are improved.

Description

TECHNICAL FIELD The present invention relates to a composition for hair loss prevention and hair growth promotion,

The present invention relates to a composition for preventing hair loss and promoting hair growth, and more particularly, to a composition for preventing hair loss and promoting hair growth, which is used for preventing hair from dropping off abnormally abnormally or promoting hair regeneration will be.

Hair has important functions such as protecting the epithelial tissue from small abrasions and ultraviolet rays, transmitting external stimuli, and controlling body temperature. In particular, scalp hair accounts for about 20% of the human hair. It is not only protects the tofu from impact by buffering the tofu along with the physiological function of the hair, but also protects the individual personality by sex, age and position, Image, and so on.

The hair repeats the growth, regrowth, and pauses. In the normal scalp, 90-95% is in the growth phase, less than 1% is in the regenerator, 5 ~ 10% is in the resting period, more than 100 hairs are folded daily, The hair follicles enter the growth again.

Alopecia is a condition in which abnormal hair is not removed or regenerated through such a growth cycle.

Hair loss has been known to be an aging phenomenon, but it is known that a variety of factors such as genetic factors, stress, and eating habits may act.

Hair loss not only loses the physiological function of hair to a person but also affects the emotional and mental effects of reduced self-esteem, mental suffering, shame, and social insufficiency, and acts as a serious factor that deteriorates sociality. Thus, Have been used.

Minoxidil has been widely used as a transdermal application agent and Propecia has been widely used as a prophylactic or therapeutic agent for hair loss. However, due to the chemical components contained in these medicines, itching, erythema, peeling of the epidermis, It has a problem that it is not suitable for long-term use because it causes serious side effects such as disorder.

In order to solve the problems of the above-mentioned minoxidil or propecia, hair growth drugs using a natural drug extract (herbal medicine extract) have been used.

Conventional hair growth agents using natural pharmaceutical extracts are disclosed in Patent Publication No. 10-2009-0051586 (Katsushiro, Kyoji, Songhwa, Kyoemaku, Kiyomi, and Kiyomi), Patent Publication No. 10-2005-0014473 (Baekjeong, Daesan, ), Patent Registration No. 10-1445553 (Licorice, Gugija, Hassuo, Chukta-ri, use of red ginseng and ginko leaves, date of registration September 23, 2014).

Hereinafter, the hair growth inhibitor disclosed in Patent Registration No. 10-1445553 (hereinafter referred to as "conventional hair loss prevention and hair growth promoting composition") will be described.

The conventional composition for preventing hair loss and hair growth includes 2 to 5 parts by weight of licorice, 2 to 5 parts by weight of ginger, 4 to 10 parts by weight of sewage, 2 to 5 parts by weight of fowl, 2 to 5 parts by weight of red ginseng, And 0.1 to 10.0% of herbal extract, and a composite composition of biotin, zinc pyritic acid, nicotinic acid amide and dexpanthenol.

Herbal medicine extracts are obtained by alcohol extraction or hot water extraction.

However, according to the composition for preventing hair loss and hair growth, antioxidative action of Cynanchum silfordii Hemsley, anti-inflammatory and antibacterial effect of Glycyrrhiza glabra, anti-inflammatory effect of Trichosanthes Kirilowii L., The effect of redness of Gugija (the effect of darkening hair), the resurrection effect of red ginseng monocytes (promoting the growth of hair and hair by revitalizing the hair cells whose functions are deteriorated), and the antioxidative and antimicrobial effects of Ginkgo biloba And promotes hair growth. However, it does not have enough hair growth enhancement and blood flow promotion, scalp stimulation action, suppression of sebum secretion, resurrection of monocyte, nutrient supply and anti-inflammatory action necessary for preventing hair loss or promoting hair growth, The effect is limited.

Accordingly, an object of the present invention is to provide a composition for preventing hair loss and for promoting hair growth with improved hair loss prevention and hair growth promoting effect, and a method for producing the same.

According to the present invention, the above-mentioned object is achieved by a process for producing a red ginseng concentrate, comprising: 1 part by weight of a red ginseng concentrate having a solid content of 40 to 60%

10 to 20 parts by weight of Sasao, 10 to 20 parts by weight of Ganoderma lucidum, 10 to 20 parts by weight of Ganoderma lucidum, 5 to 15 parts by weight of dried ginger, 5 to 10 parts by weight of Ganoderma lucidum, 5 to 10 parts by weight of licorice and 1 to 5 parts by weight of licorice 4 to 5 parts by weight of a concentrated concentrate of the first group of natural medicines having a solid content of 40 to 60% 15 to 30 parts by weight of persimmon, 15 to 30 parts by weight of persimmon, 15 to 20 parts by weight of persimmon, 5 to 10 parts by weight of a lateral leaf, 5 to 10 parts by weight of a ginkgo leaf, and 5 to 10 parts by weight of a bottle, And 2 to 5 parts by weight of a concentrate of the second group of natural medicines.

20 to 30 parts by weight of grape leaves, 20 to 30 parts by weight of guava leaves, 20 to 30 parts by weight of upper leaves and 20 to 30 parts by weight of loquat leaves are contained in an amount of 40 to 60% And 1 to 3 parts by weight of the third group natural pharmaceutical concentrate.

The above object of the present invention is also achieved by a method for preparing a red ginseng concentrate, which comprises the steps of extracting red ginseng and concentrating red ginseng extract to prepare a red ginseng concentrate having a solid content of 40 to 60% 10-20 parts by weight of garlic, 10-20 parts by weight of ginseng root, 10-20 parts by weight of ginseng, 5-15 parts by weight of dried ginseng, 5-10 parts by weight of ginseng, 5-10 parts by weight of licorice, 1-5 parts by weight of licorice A first group of natural medicines, a first group of natural medicines, a first group of natural medicines, a first group of natural medicines, and a first group of natural medicines are concentrated to obtain a first group of natural medicinal concentrates having a solid content of 40 to 60% A step of preparing a natural agent concentrate; 15 to 30 parts by weight of Hansikucho, 15 to 30 parts by weight of Rhus herbaceousum, 15 to 20 parts by weight of Rhus herbaceousum, 5 to 10 parts by weight of papaya leaf, 5 to 10 parts by weight of Gingko leaf, and 5 to 10 parts by weight of bottle grass A second group of natural medicines concentrate preparation process for producing a second group of natural medicines concentrate having a solid content of 40 to 60% through a mixing process, an extraction process of the second group of natural medicines mixture and a concentration process of the second group of natural medicament extracts; 1 part by weight of the red ginseng concentrate prepared in the step of preparing the red ginseng concentrate and 4 to 5 parts by weight of the concentrated concentrate of the first group of natural medicaments prepared in the step of preparing the concentrate of the first group natural medicines, And 2 to 5 parts by weight of the concentrate of the second group of natural medicines prepared.

And further comprising a step of preparing a plum concentrate to produce a plum concentrate having a solid content of 40 to 60% through an extraction process of plum and a concentrate process of plum extract so as to increase the effective ingredient of the ginseng saponin and the incense of plum; The red ginseng concentrate is prepared by adding 0.5 to 1 part by weight of the plum concentrate prepared in the step of preparing the plum concentrate to 100 parts by weight of the red ginseng extract, aging the mixture at 7 to 8 ° C for 12 to 24 hours, It is preferable to conduct the step of irradiating the red ginseng extract with an ultrasonic wave at an ultrasonic frequency of 30 to 40 KHz at 50 ° C to 60 ° C for 20 to 30 minutes before the concentration process of the red ginseng extract.

Therefore, according to the present invention, it is possible to provide a method for the treatment and / or prevention of diseases caused by red ginseng concentrate, first group natural medicinal concentrate (Hashuo, Youngsil gyu, Gosam, And grass blades) are blended to prepare a composition for preventing hair loss and promoting hair growth, the hair loss prevention and hair growth promoting effect are improved.

FIG. 1 is a flow chart showing a method for preparing a composition for preventing hair loss and promoting hair growth according to an embodiment of the present invention,
FIG. 2 is a photograph showing the hair condition of a subject before use of the hair loss prevention and hair growth promoting composition according to the embodiment of the present invention,
FIG. 3 is a photograph showing a hair condition of a subject using a composition for preventing hair loss and promoting hair growth according to an embodiment of the present invention for 3 weeks,
FIG. 4 is a photograph showing a hair condition of a subject using the composition for preventing hair loss and promoting hair growth according to an embodiment of the present invention for 5 weeks. FIG.

Hereinafter, the present invention will be described in detail with reference to the accompanying drawings.

The general properties and pharmacological effects of the natural medicines used in the present invention are as follows.

Plum (plum)

Plum (Prunus mume) is a fruit of plum tree. It is a fruit of plum tree, and various organic acids such as succinic acid, citric acid, malic acid and tartaric acid as well as sitosterol and mineral It is an alkaline food with high content. It is known to have effects such as recovery of liver function, promotion of digestion, improvement of diabetes, anticancer effect and antioxidant effect.

Red ginseng

Home-grown ginseng is steamed or steamed by other methods, and it is dried and cooked. Immune enhancement, cardiovascular control and anticancer effects have been reported.

And it is known that red ginseng restores the strength, strengthens the lungs, improves the spleen, and comforts the heart.

Hashuo

Houttuynia cordata is known to enhance liver function, to reduce fatigue, to enrich the skin, to promote the kidneys, and to contribute to hair loss prevention and wool.

In addition to the oxymethylanthraquinone derivatives chrysophanol and chrysophanol anthrone, emodin, emodinmonometalester and physcion in the root, , Lecithin, tetrahydroxystilbene and glucoside, and the like.

Young - Sil Root

Rosa multiflora roots reduce heat, regenerate moisture, remove wind, and promote blood circulation.

And Psyllium muscle contains condensation tannins (procyanidin B3 and catechin) which are highly antioxidant.

Gosam (苦蔘)

Gosam is a cleansing agent that activates beneficial bacteria of the human body and eliminates germs.

And the gosam extract inhibits 5a reductase (5a-reductase), which is good for wool.

Gunjihwang (干地黃)

Dried Persimmon is a dried herb of Rehmanniae glutinosa and contains Catalpol, Acubin, Mannitol, Glucose, Maninotriose, Vitamin A and others.

In addition, the dried persimmon juice reduces the lipid peroxidation in the serum and increases the activity of superoxide dismutase (SOD), an enzyme that plays a role in protecting cells against toxicity by converting excess oxygen ions, which are harmful to the human body, into oxygen and hydrogen peroxide And also antioxidant and anti-aging function.

Angelica (当归)

Angelica shows blood, improves circulation and blood flow, stimulates intestinal peristalsis, smoothly discharges gas in the body and helps to absorb nutrients.

Kangwon

When the hair is wrapped around the water of the cnidium rhizoma, the scalp is cleaned with shine on the hair, and it is effective for the scalp health such as promoting the hair growth.

And it has the effect of increasing the blood circulation by activating blood circulation and decreasing the blood pressure by helping the flow of energy.

Licorice

Licorice neutralizes toxicity and has effects such as antimicrobial action, antioxidant, skin soothing, anti-inflammatory action, wound treatment and metabolism of skin function.

And licorice is known to inhibit 5a reductase (5a-reductase), which is the cause of hair loss, and to have a good effect on wool.

Hansikcho

It contains saponin, protein, tannin, vitamin A and various kinds of terpene compounds.

And it is used as a baldness remedy because it makes the whitened hair black and grows the beard well.

Horseshoe

It is a natural antibiotic with strong antioxidant activity, which inhibits the growth of the fungus and is effective in preventing inflammation hair loss.

It is effective for the improvement of skin troubles such as acne and rash caused by skin because it is excellent in anti-inflammatory action, and it is also good for atopic dermatitis.

Quercitrin, which is abundant in herbs, keeps the capillaries healthy and clean, which facilitates metabolism without bruising easily.

In addition, Hwasungcho is excellent in detoxification, so it helps to detoxify heavy metals and poison caused by bacterial infection. It also helps to strengthen the body's immune system and to prevent the cancer or inflammation that may occur as a flavonoid component, And the like.

Guruscho (九節草 / 九折草)

It is effective to prevent headache and hair loss, and it is effective to prevent hair from becoming whitened, and it is known that it has effect on the dryness, the biceps, the tongue, the blood circulation, the appetite promotion, the paralysis and the neuralgia.

In addition, the choline component contained in the vernacellus is an important basic unit of acetylcholine, a chemical substance involved in memory formation in the brain, and is known to play an important role in forming a cell membrane in each body tissue .

Lateral leaf

Hyphaeae have myricetin and hinokitiol components that play an important role in the growth of the hairs.

And since the leaves are so hot, they eat a lot of hot, hot and fatty foods, and treat hair loss caused by overeating to darken hair and make hair grow.

Ginkgo leaf

Ginkgo leaf has a flavonoid component, which is a type of polyphenols that have strong antioxidant activity. It inhibits the action of reactive oxygen species (ROS) and contributes to cardiovascular disease, anti-aging, and cerebral vascular symptoms. .

And Ginkgo biloba extract has the effect of improving blood circulation and elasticity of blood vessel walls, contributing to nutrient delivery to the hair follicles.

Bottle grass

Bottle grass leaves include asiaticoside, madecasosside, asiatic acid and madecassic acid, which act to control and promote the collagen synthesis of the human body.

And Botulinum vulgaris strengthen blood vessels to promote blood circulation and is also found to help improve memory.

Grape leaves

The grape leaves contain a large amount of polyphenol compounds that prevent aging by removing active oxygen generated during cellular metabolism.

Mulberry

Mulberry leaves contain a lot of polyphenols that prevent the aging process by removing the active oxygen that arises from the metabolic process of the cell and the routine component that strengthens the capillary blood vessels.

And mulberry leaves make the blood flow better, strengthen the blood vessels, stabilize the blood pressure and lower the blood pressure continuously for a long time.

Guava leaf

Guadaba ( Psidium guajava Linn.) Leaves contain antioxidants that inhibit the formation of lipid peroxidation, which prevents aging, and polyphenols, which prevent aging by removing active oxygen generated during cellular metabolism .

Loquat leaf (loquat)

Leaf of Leek tree, that is, Leek leaf, is an amygdalin (vitamin B17) component that acts to promote blood purification, blood circulation, immunity enhancement and metabolism, analgesic action, , A saponin component that promotes organic acids and fatty acid metabolism for fatigue recovery, and a tannin component that inhibits the generation of lipid peroxidation that causes aging and prevents aging.

Table 1 shows the parts of the natural medicines constituting the composition for preventing hair loss and promoting hair growth according to the present invention.

Natural medicine Use part Natural medicine Use part Natural medicine Use part
Dry Roots, stem roots and stem blends
Sewage Roots, stems or roots and stem blends
licorice Roots, stem roots and stem blends Red ginseng Root Youngsil Ro Root Sophora Leaves, stem Grape leaves leaf GoSam Root Necklace stem Guava leaf leaf plum Fruit Pyeongbyeop leaf The top leaf Angelica Root Ginkgo leaf leaf Loquat leaf leaf Celestial Stem, root Bottle grass leaf Hansikcho stem

The meaning of the numerical threshold value according to the present invention is as follows.

If the solids content of either the red ginseng concentrate, the first group natural agent concentrate, the second group natural agent concentrate or the third group natural agent concentrate is less than 40%, it is difficult to obtain the desired effect. If the solid content exceeds 60% It gets harder.

In the process of aging the red ginseng extract by adding the concentrate of the plum gum, if the aging time is less than 12 hours, the aging is not performed properly. If the aging time is more than 24 hours, the yield is lowered.

When the ultrasound irradiation temperature is lower than 50 캜 in the step of irradiating the aged ginseng extract with the ultrasound, it is difficult to obtain the desired effect. When the ultrasound irradiation temperature is higher than 60 캜, the high-pressure effect due to the joint effect of ultrasonic waves causes excessive destruction of the active ingredient If the ultrasound frequency (energy) is lower than 30 KHz or the ultrasonic irradiation time is less than 20 minutes, the yield is lowered. If the ultrasonic frequency is higher than 40 KHz or the ultrasonic irradiation time is more than 30 minutes, And the pharmacological effect is reduced.

A method for producing a composition for preventing hair loss and promoting hair growth according to an embodiment of the present invention will be described with reference to FIG.

FIG. 1 is a flowchart illustrating a method of manufacturing a composition for preventing hair loss and promoting hair growth according to an embodiment of the present invention.

Production Example 1 (Preparation of a plum concentrate)

First, remove the seeds using a seperator to remove the foreign matter and moisture from the surface.

Next, crush the plum finely.

Next, using a hydraulic juicer, produce plums and juices from the plum pulp.

Next, concentrate the plum and juice. Here, the concentration of the plum and juice is carried out using a vacuum low-temperature concentrator to obtain a plum concentrate having a solid content of 50%.

Production Example 2 (Preparation of red ginseng concentrate)

First, the dried red ginseng is finely pulverized into powder by using a grinder or the like.

Next, the red ginseng powder is subjected to an extraction process.

Here, the extraction process of red ginseng powder was carried out by using 10 times of a mixed solvent of 70% ethanol and alkaline water (30% of alkaline water + 70% of ethanol) based on the weight of red ginseng powder at 80 kg / This is done by hot water extraction method which is heated for a time.

The separation of the red ginseng extraction process from the natural medicament described below is performed in order to differentiate extraction conditions in order to enhance the extraction efficiency without destroying the active ingredient such as saponin of red ginseng.

Next, based on 100 parts by weight of the red ginseng extract, 1 part by weight of the plum concentrate was added and aged at 8 DEG C for 15 hours. By thus aging the red ginseng in the state in which the ginseng concentrate is added, the fragrance of the ginseng and the active ingredient of red ginseng saponin can be increased.

Next, the red ginseng extract which has been subjected to the aging process is irradiated at 60 ° C at an ultrasonic frequency of 40 KHz for 20 minutes.

Next, the extract of red ginseng which has undergone ultrasonic irradiation process is concentrated. Here, the concentration of the red ginseng extract is performed by filtration using a 200-mesh filter apparatus, and then a red ginseng concentrate having a solid content of 50% is obtained using a vacuum low-temperature concentrator.

Preparation Example 3 (Production of the concentrate of the first group natural medicines)

First, prepare dassoo, ginseng, ginseng, ginseng, ginseng, ginseng, and licorice (group 1 natural medicines) with foreign substances and moisture removed.

Next, the first group of natural medicines are weighed so that the ratio of 200 g of Hasegos, 200 g of Gosil, 200 g of gosam, 150 g of dried ginseng, 100 g of Angelica gigas, 100 g of licorice and 50 g of licorice are obtained.

Next, the first group of natural medicines are pulverized to a size of 120 mesh using a pulverizer or the like.

Next, the extraction process is performed on the first group of natural pharmaceutical powder mixtures.

Here, the extraction process of the first group of natural drug powder mixture is performed by extracting 15 times of alkaline water based on the weight of the first group of natural drug powder mixture as an extraction solvent, heating it at 80 占 폚 for 7 hours under a pressure of 2.0 kg / .

Next, the first group natural drug extract is concentrated. Here, the concentration of the first group of natural drug extracts is carried out by filtration using a 200-mesh filtration apparatus, followed by obtaining a concentrate of the first group of natural medicines having a solid content of 50% by using a vacuum low-temperature concentrator.

Production Example 4 (Production of second group natural pharmaceutical concentrate)

First of all, we prepare Hanshikoshi, Hwaseongcho, Kwangsikcho, Hwasobyeol, Ginkgo biloba, and Bottle grass leaf (2nd group natural medicine) which are removed from foreign matter and moisture.

Next, the second group of natural medicines are weighed so as to have a ratio of 250g, 250g, 250g, 250g, 100g, 100g, 100g.

The second group of natural drugs, then weighed, is boiled for 1 hour at 100 ° C.

Next, the second group natural medicines that have been subjected to the steaming process are dried.

Next, the second group of natural medicines that have undergone the drying process using a grinder or the like is pulverized and pulverized to a size of 120 mesh.

Next, the powder mixture of the second group of natural medicines is subjected to an extraction process.

Here, in the extraction process of the second group of natural pharmaceutical powder mixture, 15 times of alkaline water based on the weight of the mixture of the second group of natural pharmaceutical powders is extracted with hot water extraction which is heated at 90 占 폚 for 5 hours under a pressure of 2.0 kg / .

Next, the extract of the second group of natural medicines is concentrated. Here, the concentration process of the second group of natural drug extracts is carried out by using a 200-mesh filter apparatus to obtain a second group of natural agent concentrates having a solid content of 50% by using a vacuum low-temperature concentrator.

Production Example 5 (Production of third group natural pharmaceutical concentrate)

First, prepare grape leaves, guava leaves, top leaves and loquat leaves with foreign matter and moisture removed.

Next, the third group of natural medicines is weighed so as to have a ratio of 25 parts by weight of grape leaves, 25 parts by weight of guava leaves, 25 parts by weight of upper leaves and 25 parts by weight of loquat leaves.

Next, the third group of natural drugs weighed is boiled for 30 minutes at 100 < 0 > C.

Next, the third group natural medicines that have been subjected to the steaming process are dried.

Next, the third group of natural medicines that have undergone the drying process using a pulverizer or the like is pulverized and pulverized to a size of 120 mesh.

Next, the powder mixture of the third group of natural medicines is subjected to an extraction process.

Here, in the extraction process of the third group of natural pharmaceutical powder mixture, 20 times of alkaline water based on the weight of the mixture of the third group of natural pharmaceutical powders is extracted with hot water extraction which is heated at 90 占 폚 for 3 hours under a pressure of 2.0 kg / .

Next, the extract of the third group of natural medicines is concentrated. Here, the concentration process of the third group natural drug extract is performed by using a 200-mesh filter apparatus to obtain a concentrate of the third group of natural medicines having a solid content of 50% by using a vacuum low-temperature concentrator.

Production Example 6 (mixing of concentrated liquid)

First, 1 part by weight of the red ginseng concentrate obtained in Preparation Example 2, 5 parts by weight of the first group natural drug concentrate obtained in Preparation Example 3, 3 parts by weight of the second group natural drug concentrate obtained in Preparation Example 4, And 3 parts by weight of the natural drug concentrate.

Next, the compound concentrate is subjected to a filtration step (to filter out residue components) and a sterilization step.

Next, the combined concentrate obtained through the filtration step and the sterilization step is placed in a stirrer and stirred.

In the embodiment described above, hot water extraction is used as an extraction method, but ethanol extraction, ultrasonic extraction, and the like can be used.

In the above-described embodiment, the first group of natural medicines are mixed and powdered, but the first group of natural medicines can be separately pulverized (the powdery process is applied to the sake) The powdery process is performed on the root muscle of the root).

Likewise, the second group natural medicines and the third group natural medicines can be individually subjected to the pulverization process.

The composition for preventing hair loss and hair growth of the present invention can be used by transdermal administration such as direct application or spreading on the scalp and can be applied to hair tonic, hair lotion, hair cream, shampoo, rinse, cream, gel, patch, spray, And the like.

Formulation Example 1 (Hair tonic)

A hair tonic having the ingredients as shown in Table 2 was prepared by adding an excipient, a stabilizer, a preservative, a buffer, and the like to the hair loss prevention and hair growth promoting composition of the present invention.

ingredient weight% Composition for preventing hair loss and promoting hair growth according to one embodiment of the present invention 12.0 Vitamin B5 (Panthenol), B7 (Biotin), Nicotinamide 2.0 Tcopheryl Acetate 1.0 Scalp penetration agent Dimethyl sulfoxide (DMSO), Triton-x 7.0 Spices lilac Suitable amount Moisturizer 1,3-butylene glycol, glycerin 5.0 Hydrogenated Castor Oil 3.0 Solvent Alkaline and SD Alcohol 40 to 100%

As shown in Formulation Example 1 (hair tonic), there is no need to add a preservative because it contains natural herbicide, ginkgo leaf, licorice and the like which are natural preservatives.

Formulation Example 2 (Shampoo)

A surfactant, a foam stabilizer, a moisturizer, a preservative, and the like were added to the hair loss prevention and hair growth promoting composition of the present invention to prepare a shampoo having the components as shown in Table 3.

ingredient weight% Composition for preventing hair loss and promoting hair growth according to one embodiment of the present invention 12.0 Sodium Laural Sulfate (SLS) 25.0 Sodium laureth sulfate 15.0 Propylene glycol 3.0 Lauramide MEA 4.0 Roseberry oil 3.0 Glucamate 1.0 Alkaline water to 100

In order to confirm the hair loss prevention effect and the hair growth promoting effect of the hair loss prevention and hair growth promoting composition of the present invention, clinical tests were conducted using both formulation example 1 (hair tonic) and formulation example 2 (shampoo) simultaneously.

(Hair tonic) and formulation 2 (shampoo) were administered to a male subject with 15 hair loss symptoms (mean age 47 years, except those who were taking topical or oral pharmaceuticals that could affect hair growth) ).

Formulation Example 2 (shampoo) and Formulation Example 1 (hair tonic) were simultaneously used for 2 months in the morning and evening (twice / day), and the method of using each composition was as follows.

First, dissolve in lukewarm water, soak Formulation Example 2 (shampoo) on the hair, massage it appropriately, rinse in water after 3 ~ 5 minutes, and dry.

Next, dissolve Formulation Example 1 (hair tonic) at about 0.5 to 0.75 ml at the hair loss site and massage the scalp for 10 to 15 seconds.

The subjects were visually observed for weekly scalp and hair condition with no abstinence or recommendation for alcohol consumption or smoking, and the results were as shown in Table 4.

Period of use By rating Number of people 2 weeks The itching of the scalp calms down and hair loss stops 13 people 3 weeks One to two centimeters of fuzzy hair resurfaced in the hair loss part. 12 people 7 weeks Black as the resurrected hair grows 10 people 2 months The thickness of black hair increases 9 people

And FIG. 2 is a photograph of a hair condition of a subject before using the hair loss prevention and hair growth promoting composition according to the embodiment of the present invention. FIG. 3 is a photograph showing the hair loss prevention and hair growth promoting composition according to the embodiment of the present invention FIG. 4 is a photograph showing a hair condition of a subject using the composition for preventing hair loss and promoting hair growth according to an embodiment of the present invention for 5 weeks. FIG.

More than 80% of the subjects were able to calm the itchiness of the scalp and stop the progression of hair loss after 2 weeks of use. The hair follicle began to grow on the scalp after 3 weeks of use and showed rapid hair follicle growth.

More than 60% of the subjects had dark and firm hair as the hair revived after 7 weeks of use and increased the thickness of black hair within 2 months of use.

Although it is the naked eye, it has been found through the present invention that the hair follicle growth, the density of the high hair, and the shape of the hair are changed into a straight, long and thick shape.

The same effects as in the above test examples are as follows: (1) vasodilatation and blood flow promoting effect by extracts of Hwasoo, Angelica gigas Nakai, Ginkgo biloba, and Botulinum vulgaris; (vasodilating effect and blood flow promoting effect of peripheral blood vessels in order to facilitate nutrient supply to papillomas and blanket); (Stimulation of the scalp by expanding the blood vessels and improving blood circulation), ③ inhibiting the secretion of sebum by the extracts of Sophora edulis and Sophora edulis (which causes the generation of peroxides and dandruff ④ Reduced cell renewal effect by red ginseng, papaya leaf, perilla leaf and nonpeak leaf extract (promoting hair growth and hair growth by reviving degraded hair cells) , ⑤ nutrient supply by guava leaves and licorice extract (nutrients to monocytes whose function has been impaired by circulatory disturbance of erythrocyte vascular itamin, and amino acids), ⑥ anti-inflammatory action by the extract of grape leaves, hansilikcho, gosam, and grape leaf extract (suppressing the inflammation of the scalp caused by dandruff or external stimulation and keeping it healthy) .

Then, 0.5 to 1 part by weight of the plum concentrate is added to 100 parts by weight of the red ginseng extract before the concentration step, and the red ginseng extract is aged at 7 to 8 ° C for 12 to 24 hours. And the ultrasonic wave is irradiated at an ultrasonic frequency of 30 to 40 KHz for 20 to 30 minutes to increase the fragrance of the plum and the active ingredient of red ginseng saponin.

Claims

1 part by weight of a red ginseng concentrate having a solid content of 40 to 60%;
10 to 20 parts by weight of Sasao, 10 to 20 parts by weight of Ganoderma lucidum, 10 to 20 parts by weight of Ganoderma lucidum, 5 to 15 parts by weight of dried ginger, 5 to 10 parts by weight of Ganoderma lucidum, 5 to 10 parts by weight of licorice and 1 to 5 parts by weight of licorice 4 to 5 parts by weight of a concentrated concentrate of the first group of natural medicines having a solid content of 40 to 60%
15 to 30 parts by weight of persimmon, 15 to 30 parts by weight of persimmon, 15 to 20 parts by weight of persimmon, 5 to 10 parts by weight of a lateral leaf, 5 to 10 parts by weight of a ginkgo leaf, and 5 to 10 parts by weight of a bottle, And 2 to 5 parts by weight of a concentrated concentrate of the second group of natural medicines.

The method according to claim 1,
1 to 3 parts by weight of a concentrate of a third group natural agent having a solid content of 40 to 60% obtained from 20 to 30 parts by weight of grape leaves, 20 to 30 parts by weight of guava leaves, 20 to 30 parts by weight of upper leaves and 20 to 30 parts by weight of loquat leaves The composition for preventing hair loss and promoting hair growth according to claim 1,

A red ginseng concentrate preparation step of preparing a red ginseng concentrate having a solid content of 40 to 60% through an extraction process of red ginseng and a concentration process of red ginseng extract;
10-20 parts by weight of garlic, 10-20 parts by weight of ginseng root, 10-20 parts by weight of ginseng, 5-15 parts by weight of dried ginseng, 5-10 parts by weight of ginseng, 5-10 parts by weight of licorice, 1-5 parts by weight of licorice A first group of natural medicines, a first group of natural medicines, a first group of natural medicines, a first group of natural medicines, and a first group of natural medicines are concentrated to obtain a first group of natural medicinal concentrates having a solid content of 40 to 60% A step of preparing a natural agent concentrate;
15 to 30 parts by weight of Hansikucho, 15 to 30 parts by weight of Rhus herbaceousum, 15 to 20 parts by weight of Rhus herbaceousum, 5 to 10 parts by weight of papaya leaf, 5 to 10 parts by weight of Gingko leaf, and 5 to 10 parts by weight of bottle grass A second group of natural medicines concentrate preparation process for producing a second group of natural medicines concentrate having a solid content of 40 to 60% through a mixing process, an extraction process of the second group of natural medicines mixture and a concentration process of the second group of natural medicament extracts;
1 part by weight of the red ginseng concentrate prepared in the step of preparing the red ginseng concentrate and 4 to 5 parts by weight of the concentrated concentrate of the first group of natural medicaments prepared in the step of preparing the concentrate of the first group natural medicines, And 2 to 5 parts by weight of the concentrate of the second group of natural medicines prepared.

The method of claim 3,
20 to 30 parts by weight of grape leaves, 20 to 30 parts by weight of guava leaves, 20 to 30 parts by weight of upper leaves, 20 to 30 parts by weight of loquat leaf (third group natural medicines), extraction process of third group natural medicines mixture And a third group of natural medicament concentrates through a concentration process of the third group natural medicament extract to produce a third group natural medicament concentrate having a solid content of 40 to 60%;
Wherein the concentrate is mixed with 1 to 3 parts by weight of the concentrated concentrate of the third group of natural medicines.

The method according to claim 3 or 4,
Further comprising a step of producing a plum concentrate by preparing a plum concentrate having a solid content of 40 to 60% through an extraction process of plum and a concentrating process of plum extract;
The red ginseng concentrate is prepared by adding 0.5 to 1 part by weight of the plum concentrate prepared in the step of preparing the plum concentrate to 100 parts by weight of the red ginseng extract, aging the mixture at 7 to 8 ° C for 12 to 24 hours, A method for preparing a composition for preventing hair loss and promoting hair growth, characterized in that the step of irradiating the red ginseng extract with ultrasonic waves at an ultrasonic frequency of 30 to 40 KHz at 50 ° C to 60 ° C for 20 to 30 minutes is performed before the concentration step of the red ginseng extract .