KR20110046394A - X-선 마커 입자 및 mr 마커를 갖는 의료 기구 - Google Patents
X-선 마커 입자 및 mr 마커를 갖는 의료 기구 Download PDFInfo
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- KR20110046394A KR20110046394A KR1020107028882A KR20107028882A KR20110046394A KR 20110046394 A KR20110046394 A KR 20110046394A KR 1020107028882 A KR1020107028882 A KR 1020107028882A KR 20107028882 A KR20107028882 A KR 20107028882A KR 20110046394 A KR20110046394 A KR 20110046394A
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- G—PHYSICS
- G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
- G03B—APPARATUS OR ARRANGEMENTS FOR TAKING PHOTOGRAPHS OR FOR PROJECTING OR VIEWING THEM; APPARATUS OR ARRANGEMENTS EMPLOYING ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ACCESSORIES THEREFOR
- G03B42/00—Obtaining records using waves other than optical waves; Visualisation of such records by using optical means
- G03B42/02—Obtaining records using waves other than optical waves; Visualisation of such records by using optical means using X-rays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2420/00—Materials or methods for coatings medical devices
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Heart & Thoracic Surgery (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Vascular Medicine (AREA)
- Surgery (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Dermatology (AREA)
- Pulmonology (AREA)
- Biophysics (AREA)
- Anesthesiology (AREA)
- General Physics & Mathematics (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Materials For Medical Uses (AREA)
- Apparatus For Radiation Diagnosis (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102008024976.9 | 2008-05-23 | ||
| DE102008024976A DE102008024976A1 (de) | 2008-05-23 | 2008-05-23 | Medizinisches Instrument |
| PCT/EP2009/003685 WO2009141165A2 (de) | 2008-05-23 | 2009-05-25 | Medizinisches instrument |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20110046394A true KR20110046394A (ko) | 2011-05-04 |
Family
ID=41151770
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020107028882A Ceased KR20110046394A (ko) | 2008-05-23 | 2009-05-25 | X-선 마커 입자 및 mr 마커를 갖는 의료 기구 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20110166439A1 (https=) |
| EP (2) | EP3117843A1 (https=) |
| JP (2) | JP5734847B2 (https=) |
| KR (1) | KR20110046394A (https=) |
| CN (1) | CN102036695B (https=) |
| CA (1) | CA2724826C (https=) |
| DE (1) | DE102008024976A1 (https=) |
| WO (1) | WO2009141165A2 (https=) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20160017185A (ko) | 2014-07-31 | 2016-02-16 | 주식회사 시브이바이오 | 고시각성 혈관용 스텐트 |
| KR20160090699A (ko) | 2015-01-22 | 2016-08-01 | 주식회사 바이오알파 | 생체 흡수용 방사선 불투과성 마커 조성물 및 이를 포함하는 수술용 물품 |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2450067A1 (en) * | 2010-10-18 | 2012-05-09 | MaRVis Technologies GmbH | Medical device |
| EP2484388A1 (en) | 2011-02-05 | 2012-08-08 | MaRVis Technologies GmbH | Implantable or insertable MRI-detectable medical device having a coating comprising paramagnetic ions and a process for preparing it |
| DE102011081445A1 (de) | 2011-08-23 | 2013-02-28 | Epflex Feinwerktechnik Gmbh | Medizinischer Führungsdraht und Herstellungsverfahren |
| DE102011113816A1 (de) * | 2011-09-21 | 2013-03-21 | Marvis Technologies Gmbh | Medizinische Vorrichtung zum Einbringen in den menschlichen oder tierischen Körper |
| DE102011118719A1 (de) | 2011-11-16 | 2013-05-16 | Brabender Gmbh & Co.Kg | Vorrichtung zum Extrudieren eines medizinischen Instruments, das in einen menschlichen oder tierischen Körper einführbar ist |
| JP6032729B2 (ja) * | 2012-05-08 | 2016-11-30 | 国立研究開発法人理化学研究所 | イメージングマーカーおよびその利用 |
| EP2692365A1 (en) | 2012-08-03 | 2014-02-05 | MaRVis Medical GmbH | Implantable or insertable MRI-detectable medical device having a coating comprising paramagnetic ions and a process for preparing it |
| DE102012214785A1 (de) | 2012-08-20 | 2014-02-20 | Epflex Feinwerktechnik Gmbh | Medizinischer Führungsdraht mit MR-Marker |
| DE102012222356B4 (de) | 2012-12-05 | 2017-03-16 | Epflex Feinwerktechnik Gmbh | Medizinisches Steinfangkorbinstrument |
| DE102014005994A1 (de) * | 2014-04-23 | 2015-10-29 | Marvis Medical Gmbh | Stabförmiger Körper und medizinisches lnstrument |
| DE102014005901A1 (de) | 2014-04-25 | 2015-10-29 | Marvis Medical Gmbh | Vorrichtung zum Extrudieren eines strukturierten Extrudats |
| DE102015114488A1 (de) | 2015-08-31 | 2017-03-02 | Marvis Medical Gmbh | Vorrichtung zum Extrudieren eines strukturierten Extrudats |
| WO2019109063A2 (en) | 2017-12-03 | 2019-06-06 | Paul Ram H Jr | Mri compatible interventional wireguide |
| DE102018203102B3 (de) | 2018-03-01 | 2019-05-16 | Epflex Feinwerktechnik Gmbh | Führungsdraht für medizinische MR-Anwendungen |
| DE102021111091A1 (de) * | 2021-04-29 | 2022-11-03 | Marvis Interventional Gmbh | Magnetresonanztomographie sicheres (MR-sicheres) Steuerseil |
| WO2023079288A1 (en) * | 2021-11-03 | 2023-05-11 | Endomagnetics Ltd. | Improvements in or relating to implantable ferromagnetic markers |
| CN119280620B (zh) * | 2024-12-10 | 2025-03-28 | 万漉医疗科技(江苏)有限公司 | 一种用于治疗手术的血管导丝 |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4257421A (en) * | 1979-01-10 | 1981-03-24 | Health Development Corporation | Gastro-intestinal tube guide and stiffener |
| EP0247156B1 (en) | 1985-11-18 | 1993-06-23 | Access Pharmaceuticals Inc. | Polychelating agents for image and spectral enhancement (and spectral shift) |
| US5154179A (en) | 1987-07-02 | 1992-10-13 | Medical Magnetics, Inc. | Device construction and method facilitating magnetic resonance imaging of foreign objects in a body |
| US5251640A (en) * | 1992-03-31 | 1993-10-12 | Cook, Incorporated | Composite wire guide shaft |
| ATE195258T1 (de) * | 1993-04-14 | 2000-08-15 | Pharmacyclics Inc | Medizinische vorrichtungen und materialien mit erhöhter sichtbarkeit bei magnetischer bildgebung |
| US5744958A (en) | 1995-11-07 | 1998-04-28 | Iti Medical Technologies, Inc. | Instrument having ultra-thin conductive coating and method for magnetic resonance imaging of such instrument |
| US5705014A (en) * | 1996-03-22 | 1998-01-06 | General Electric Company | Carbon fiber magnetic resonance compatible instruments |
| US6458088B1 (en) | 1997-03-27 | 2002-10-01 | Cordis Corporation | Glass core guidewire compatible with magnetic resonance |
| JPH10290839A (ja) * | 1997-04-21 | 1998-11-04 | Terumo Corp | ガイドワイヤ |
| US6174330B1 (en) * | 1997-08-01 | 2001-01-16 | Schneider (Usa) Inc | Bioabsorbable marker having radiopaque constituents |
| US6361759B1 (en) | 1998-05-26 | 2002-03-26 | Wisconsin Alumni Research Foundation | MR signal-emitting coatings |
| WO2001095794A1 (en) * | 2000-06-12 | 2001-12-20 | Cordis Corporation | Vascular guidewire for magnetic resonance and/or fluoroscopy |
| DE10107750A1 (de) | 2000-06-23 | 2003-11-06 | Mri Devices Daum Gmbh | Kernspintauglicher Führungsdraht |
| DE10040381C1 (de) | 2000-08-11 | 2002-06-06 | Schering Ag | Perfluoralkylhaltige Komplexe mit Zuckerresten, Verfahren zu deren Herstellung und ihre Verwendung |
| CN1203904C (zh) | 2000-09-11 | 2005-06-01 | 联合碳化化学及塑料技术公司 | 具有磁共振成像衬比度的亲水、润滑医疗器械 |
| DE10057038A1 (de) | 2000-11-17 | 2002-05-29 | Rehau Ag & Co | Medizinische Arbeitsmittel |
| US6574497B1 (en) * | 2000-12-22 | 2003-06-03 | Advanced Cardiovascular Systems, Inc. | MRI medical device markers utilizing fluorine-19 |
| US20030208142A1 (en) * | 2001-06-12 | 2003-11-06 | Boudewijn Alexander C | Vascular guidewire for magnetic resonance and /or fluoroscopy |
| US6585755B2 (en) * | 2001-06-29 | 2003-07-01 | Advanced Cardiovascular | Polymeric stent suitable for imaging by MRI and fluoroscopy |
| US6911017B2 (en) | 2001-09-19 | 2005-06-28 | Advanced Cardiovascular Systems, Inc. | MRI visible catheter balloon |
| US20040143180A1 (en) * | 2001-11-27 | 2004-07-22 | Sheng-Ping Zhong | Medical devices visible under magnetic resonance imaging |
| US20030100829A1 (en) * | 2001-11-27 | 2003-05-29 | Sheng-Ping Zhong | Medical devices with magnetic resonance visibility enhancing material |
| US7758520B2 (en) * | 2003-05-27 | 2010-07-20 | Boston Scientific Scimed, Inc. | Medical device having segmented construction |
| US20050255317A1 (en) * | 2003-09-22 | 2005-11-17 | Advanced Cardiovascular Systems, Inc. | Polymeric marker with high radiopacity for use in medical devices |
| US8067073B2 (en) * | 2004-03-25 | 2011-11-29 | Boston Scientific Scimed, Inc. | Thermoplastic medical device |
| DE102004028367A1 (de) | 2004-06-11 | 2005-12-29 | Biotronik Vi Patent Ag | Katheter-Führungsdraht insbesondere für kardio-vaskuläre Eingriffe |
| DE102005030472A1 (de) | 2005-06-28 | 2007-01-04 | Joachim-Georg Pfeffer | Stabförmiger Körper |
| EP1818054A1 (en) | 2006-02-10 | 2007-08-15 | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts | Use of a gadolinium chelate for labeling cells |
| CN101007189A (zh) * | 2007-01-12 | 2007-08-01 | 李艳芳 | 一种含药生物降解显影微球型血管栓塞材料 |
-
2008
- 2008-05-23 DE DE102008024976A patent/DE102008024976A1/de not_active Withdrawn
-
2009
- 2009-05-25 CA CA2724826A patent/CA2724826C/en active Active
- 2009-05-25 US US12/993,428 patent/US20110166439A1/en not_active Abandoned
- 2009-05-25 CN CN200980118695.0A patent/CN102036695B/zh not_active Expired - Fee Related
- 2009-05-25 KR KR1020107028882A patent/KR20110046394A/ko not_active Ceased
- 2009-05-25 WO PCT/EP2009/003685 patent/WO2009141165A2/de not_active Ceased
- 2009-05-25 JP JP2011509901A patent/JP5734847B2/ja not_active Expired - Fee Related
- 2009-05-25 EP EP16020095.2A patent/EP3117843A1/de not_active Withdrawn
- 2009-05-25 EP EP09749655.8A patent/EP2315607B1/de not_active Not-in-force
-
2015
- 2015-04-15 JP JP2015083158A patent/JP6281041B2/ja not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20160017185A (ko) | 2014-07-31 | 2016-02-16 | 주식회사 시브이바이오 | 고시각성 혈관용 스텐트 |
| KR20160090699A (ko) | 2015-01-22 | 2016-08-01 | 주식회사 바이오알파 | 생체 흡수용 방사선 불투과성 마커 조성물 및 이를 포함하는 수술용 물품 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2009141165A3 (de) | 2010-10-21 |
| EP3117843A1 (de) | 2017-01-18 |
| JP2015163211A (ja) | 2015-09-10 |
| JP6281041B2 (ja) | 2018-02-21 |
| CA2724826C (en) | 2016-04-12 |
| CA2724826A1 (en) | 2009-11-26 |
| DE102008024976A1 (de) | 2009-12-17 |
| JP2011520538A (ja) | 2011-07-21 |
| EP2315607B1 (de) | 2016-05-04 |
| US20110166439A1 (en) | 2011-07-07 |
| CN102036695A (zh) | 2011-04-27 |
| CN102036695B (zh) | 2016-03-23 |
| JP5734847B2 (ja) | 2015-06-17 |
| WO2009141165A2 (de) | 2009-11-26 |
| EP2315607A2 (de) | 2011-05-04 |
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