KR20100102389A - Valuable anti-wrinkle cosmetics composition contaning natural extract - Google Patents

Valuable anti-wrinkle cosmetics composition contaning natural extract Download PDF

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KR20100102389A
KR20100102389A KR1020090020737A KR20090020737A KR20100102389A KR 20100102389 A KR20100102389 A KR 20100102389A KR 1020090020737 A KR1020090020737 A KR 1020090020737A KR 20090020737 A KR20090020737 A KR 20090020737A KR 20100102389 A KR20100102389 A KR 20100102389A
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extract
natural extract
weight
wrinkle
natural
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KR101208404B1 (en
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빈중국
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나빈생활과학 주식회사
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/02Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
    • A61K35/08Mineral waters; Sea water
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/02Algae
    • A61K36/03Phaeophycota or phaeophyta (brown algae), e.g. Fucus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/33Cactaceae (Cactus family), e.g. pricklypear or Cereus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/965Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of inanimate origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations

Abstract

PURPOSE: A functional cosmetic composition for improving anti-wrinkle is provided to ensure collagen biosynthesis and to prevent toxicity and irritation to human body. CONSTITUTION: A functional cosmetic composition for improving anti-wrinkle contains 0.5-0.6 weight parts of tackifier, 0.2-0.4 weight parts of preservative, 0.04-0.1 weight parts of skin conditioning agent, 0.005-0.02 weight parts of sea water, and 0.01-0.02 weight parts of natural extract based on 100 weight parts of solvent. The tackifier is hydroxyethylcellulose. The preservative is propyl paraben, butyl paraben, methyl paraben, phenoxyethanol, or salicylic acid. The skin conditioning agent is adenosine, sodium hyluronate, acetyl hexapeptide-8 or human oligopeptide-1. The natural extract is opuntia ficus-indica extract, Fucus Vesiculosus Extract or mixture thereof.

Description

천연추출물 함유 기능성 주름개선용 조성물{Valuable anti-wrinkle cosmetics composition contaning natural extract}Functional anti-wrinkle composition containing natural extracts {Valuable anti-wrinkle cosmetics composition contaning natural extract}

본 발명은 주름개선 효과가 우수한 천연추출물을 함유한 기능성 주름 개선용 조성물에 관한 것이다. The present invention relates to a functional wrinkle improvement composition containing a natural extract excellent in wrinkle improvement.

일반 적으로, 피부 주름은 피부의 수분 함유량, 콜라겐 함유량 및 외부 환경에 대한 면역 작용 능력 등 여러 가지 요소들에 의해 생성되는 것으로 알려져 있다. 이중 주름의 형성에 가장 큰 영향을 미치는 것은 콜라겐의 생성량이다.In general, skin wrinkles are known to be produced by a number of factors, including the skin's moisture content, collagen content and its ability to act on the environment. The greatest influence on the formation of double wrinkles is the amount of collagen produced.

콜라겐은 피부의 섬유아세포에서 생성되는 주요 기질 단백질로서 세포외 간질에 존재하고 생체 단백질 총중량의 30%를 차지하며 나선형 구조를 하고 있다. 주된 기능으로는 피부의 기계적 견고성, 결합조직의 저항력과 조직의 결합력, 세포접Collagen is a major matrix protein produced in the fibroblasts of the skin and is present in extracellular epilepsy and accounts for 30% of the total weight of biological proteins and has a spiral structure. Its main functions include mechanical firmness of the skin, resistance of connective tissue and tissue adhesion, and cell contact.

착의 지탱 등의 기능을 통해 피부에 탄력을 부여하는 주요 성분으로 알려져 있다. 자연 노화에 따른 세포활성의 감소와 같은 내적 요인에 의해 콜라겐 함량이 감소될 뿐만 아니라, 여러 가지 유해 환경에 의한 스트레스 증가 및 태양 광선에 의한 활성 산소 종의 증가와 같은 외적 요인에 의하여 콜라겐 생합성이 감소되고, 콜라겐 분해가 증가되는 문제점이 있다. 이러한 문제점을 극복해서 피부주름을 개선하려는 노력이 꾸준히 시도되고 있다.It is known as a major ingredient that gives elasticity to skin through functions such as support of wear. Not only does collagen content decrease due to internal factors such as decreased cellular activity due to natural aging, but also collagen biosynthesis decreases due to external factors such as increased stress caused by various harmful environments and increased free radical species caused by sunlight. There is a problem that collagen decomposition is increased. Overcoming these problems, efforts to improve skin wrinkles have been steadily attempted.

콜라겐 합성 촉진물질로서 기존에 레티노산(retinoic acid), TGF-beta, 동물태반 유래의 단백질 (JP8-231370), 베툴린산(betulinic acid) (JP8-208424), 클로렐라 추출물(JP40523), 율피추출물 (KR-10-1997-0058952) 등이 알려져 있다. 그러나, 레티노산은 매우 불안정한 물질로서 빛(자외선), 수분, 열, 공기(산소)에 민감하여 쉽게 화학적인 변화를 일으키는 문제점이 있고, 뿐만 아니라 피부에 적용시 자극, 발적 등의 피부 트러블을 유발한다고 보고되어 있다. 따라서, 생체에서의 안전성, 안정성이 높고 콜라겐 합성율이 높은 새로운 콜라겐 합성 촉진제의 개발이 절실히 요구되고 있다.Retinoic acid, TGF-beta, protein from animal placenta (JP8-231370), betulinic acid (JP8-208424), chlorella extract (JP40523), ulpi extract ( KR-10-1997-0058952) and the like are known. However, retinoic acid is a very unstable substance, which is sensitive to light (ultraviolet rays), moisture, heat, and air (oxygen), and easily causes chemical changes, as well as causing skin problems such as irritation and redness when applied to the skin. Reported. Therefore, there is an urgent need for the development of new collagen synthesis promoters having high safety and stability in vivo and high collagen synthesis rate.

따라서, 본 발명은 상기한 문제점을 해결하기 위해 안출한 것으로서, 본 발명에 따라 새로이 밝혀진 천연추출물을 포함하는 기능성 주름 개선용 조성물을 제공하는 것을 그 해결과제로 한다.Therefore, the present invention has been made to solve the above problems, and to provide a composition for improving functional wrinkles comprising a newly extracted natural extract according to the present invention as its problem.

본 발명자들은 천연물을 스크리닝한 결과, 선인장추출물과 갈조류 추출물이 콜라겐 생합성을 촉진시키며, 인체 피부 주름개선 효과가 뛰어나고, 안전성이 우수해 주름개선용 조성물의 유효성분이 될 수 있음을 확인함으로써 발명을 완성하였다.The present inventors screened natural products, and completed the invention by confirming that the cactus extract and the brown algae extract promote collagen biosynthesis, have an excellent effect on the improvement of human skin wrinkles, and have excellent safety and can be effective ingredients of the composition for improving wrinkles. .

상기한 과제를 해결한 본 발명의 천연추출물 함유 기능성 주름개선용 조성물은 용제 100 중량부에 대하여 점증제 0.5 ~ 0.6중량부, 방부제 0.2 ~ 0.4 중량부, 스킨컨디셔닝제 0.04 ~ 0.1중량부, 씨워터(See water) 0.01 ~ 0.05 중량부 및 천연추출물 0.01 ~ 0.02 중량부를 혼합하여 되는 것을 특징으로 한다. The natural extract-containing functional wrinkle improvement composition of the present invention solved the above problems is 0.5 to 0.6 parts by weight of thickener, 0.2 to 0.4 parts by weight of preservative, 0.04 to 0.1 parts by weight of skin conditioner, sea water based on 100 parts by weight of solvent (See water) It is characterized by mixing 0.01 to 0.05 parts by weight and 0.01 to 0.02 parts by weight of the natural extract.

또한, 본 발명의 천연추출물 함유 기능성 주름개선용 조성물은 상기 점증제로 하이드록시에틸셀룰로스를 사용하는 것을 특징으로 한다.In addition, the natural extract-containing functional wrinkle improvement composition of the present invention is characterized by using hydroxyethyl cellulose as the thickener.

또한, 본 발명의 천연추출물 함유 기능성 주름개선용 조성물은 상기 방부제로 프로필 파라벤(Propyl Paraben), 부틸 파라벤(Buthyl Paraban), 메틸 파라벤(Methyl Paraben), 페녹시에탄올(Phenoxyethanol) 또는 살리실릭 산(salicylic acid)으로 이루어진 군에서 선택된 1종 또는 2종 이상의 것을 사용하는 것을 특징으로 한다. In addition, the natural extract-containing functional wrinkle improvement composition of the present invention is a propyl paraben (Propyl Paraben), butyl paraben (Buthyl Paraban), methyl paraben (Methyl Paraben), phenoxyethanol (Phenoxyethanol) or salicylic acid (salicylic) acid) is selected from the group consisting of one or two or more.

또한, 본 발명의 천연추출물 함유 기능성 주름개선용 조성물은 상기 스킨컨디셔닝제는 아데노신(Adenosine), 히아루론산나트륨(Sidium Hyaluronate), 아세틸 헥사펩타이드-8(Acetyl Hexapeptide-8), 휴먼올리고펩타이드-1(Human Oligopeptide-1)으로 이루어진 군에서 선택된 1종 또는 2종 이상의 혼합물인 것을 특징으로 한다.In addition, the natural extract containing a functional wrinkle improvement composition of the present invention, the skin conditioning agent Adenosine (Adenosine), sodium hyaluronate, acetyl hexapeptide-8 (Acetyl Hexapeptide-8), human oligopeptide-1 (Human Oligopeptide-1) is characterized in that one or a mixture of two or more selected from the group consisting of.

또한, 본 발명의 천연추출물 함유 기능성 주름개선용 조성물은 상기 천연추출물은 선인장 추출물(opuntia ficus-indica Extract), 갈조류 추출물(Fucus Vesiculosus Extract) 또는 이들의 혼합물인 것을 특징으로 한다. In addition, the natural extract-containing functional wrinkle improvement composition of the present invention is characterized in that the natural extract is a cactus extract (opuntia ficus-indica Extract), brown algae extract (Fucus Vesiculosus Extract) or a mixture thereof.

본 발명에 따르는 천연추출물 함유 기능성 주름개선용 조성물은 레티놀과 유사한 콜라겐생합성 효과를 가짐으로써 주름 개선효과가 있을 뿐 아니라, 천연추출물을 함유함으로써 인체에 어떠한 독성이나 자극이 발생하지 않아 인체사용에 안전한 효과를 가지게 된다. Functional extract for wrinkle-containing functional extracts according to the present invention has a collagen biosynthesis effect similar to retinol not only has a wrinkle improving effect, but also contains a natural extract does not cause any toxicity or irritation to the human body, which is safe for human use. Will have

이하, 본 발명을 보다 상세히 설명하면 다음과 같다. Hereinafter, the present invention will be described in more detail.

본 발명의 양태에 따르면, 본 발명은 용제에 점증제, 방부제, 스킨컨디셔닝 제, 씨워터(Sea water) 및 천연추출물을 일정량 혼합하여 이루어진다.According to an aspect of the present invention, the present invention is made by mixing a predetermined amount of a thickener, preservatives, skin conditioning agent, sea water and natural extract in a solvent.

본 발명에 따른 주름개선 조성물은 용제 100 중량부에 대하여 점증제 0.5 ~ 0.6중량부, 방부제 0.2 ~ 0.4 중량부, 스킨컨디셔닝제 0.04 ~ 0.1중량부, 씨워터(See water) 0.01 ~ 0.05 중량부 및 천연추출물 0.01 ~ 0.02 중량부를 혼합하여 된다. The wrinkle improvement composition according to the present invention is 0.5 to 0.6 parts by weight of thickener, 0.2 to 0.4 parts by weight of preservative, 0.04 to 0.1 parts by weight of skin conditioner, 0.01 to 0.05 parts by weight of sea water and 0.01 to 0.02 parts by weight of natural extracts may be mixed.

상기 점증제는 크게 한정하는 것은 아니나, 본 발명에 따르면 하이드록시에틸셀룰로스(Hydroxyethylcellulose)를 사용하는 것이 바람직하다. The thickener is not particularly limited, it is preferable to use hydroxyethyl cellulose (Hydroxyethylcellulose) according to the present invention.

상기 방부제로는 프로필 파라벤(Propyl Paraben), 부틸 파라벤(Buthyl Paraban), 메틸 파라벤(Methyl Paraben), 페녹시에탄올(Phenoxyethanol) 또는 살리실릭 산(salicylic acid)으로 이루어진 군에서 선택된 1종 또는 2종 이상의 것을 사용하며, 바람직하게는 페녹시에탄올을 사용하는 것이 좋다. 더 좋게는 상기 페녹시에탄올과 상기 나열된 방부제를 혼용하여 사용하는 것이 좋으며, 그 혼용비율은 크게 한정하지 않으며, 그 혼용된 방부제의 량이 본 발명에 따르는 방부제의 혼합량을 초과하여 사용하여서는 안된다.The preservative may be selected from the group consisting of propyl paraben, butyl paraben, methyl paraben, methyl paraben, phenoxyethanol, or salicylic acid. It is preferable to use phenoxy ethanol. More preferably, the phenoxyethanol and the above-mentioned preservatives are mixed and used, and the mixing ratio is not particularly limited, and the amount of the mixed preservatives should not exceed the mixing amount of the preservatives according to the present invention.

상기 스킨컨디셔닝제는 아데노신(Adenosine), 히아루론산나트륨(Sidium Hyaluronate), 아세틸 헥사펩타이드-8(Acetyl Hexapeptide-8), 휴먼올리고펩타이드-1(Human Oligopeptide-1)으로 이루어진 군에서 선택된 1종 또는 2종 이상의 혼합물을 사용하며, 바람직하게는 단독으로 사용하는 것보다는 2종 이상을 혼용하여 사용하는 것이 좋다.The skin conditioning agent is one or two selected from the group consisting of adenosine (Adenosine), sodium hyaluronate, acetyl hexapeptide-8, human oligopeptide-1 The above mixture is used, and preferably two or more kinds are used in combination rather than being used alone.

상기 천연추출물은 선인장 추출물(opuntia ficus-indica Extract), 갈조류 추출물(Fucus Vesiculosus Extract) 또는 이들의 혼합물을 사용하는 것이 좋으며, 바람직하게는 상기 두 추출물을 혼용하여 사용하는 것이 좋다. As the natural extract, it is preferable to use cactus extract (opuntia ficus-indica Extract), brown algae extract (Fucus Vesiculosus Extract) or a mixture thereof, and preferably use the two extracts in combination.

본 발명에 사용되는 씨워터는 해수라고도 하며, 해수의 특성은 순수의 특성과 거의 같다고 보아도 무방. 다만, 순수와 같이 4℃에서 밀도가 최대가 되지 않고, 빙점(약 -2℃)이 최대밀도가 된다. 또한, 다량의 무기물을 함유하고 있어 피부영양소 공급에 최적의 조건을 가지고 있다. 본 발명에서는 희석제의 용도로 사용되어진다.Seawater used in the present invention is also called sea water, the characteristics of sea water is almost the same as that of pure water. However, like pure water, the density does not become the maximum at 4 ° C, and the freezing point (about -2 ° C) becomes the maximum density. In addition, it contains a large amount of minerals and has the optimum conditions for supplying skin nutrients. In the present invention, it is used as a diluent.

본 발명에 사용되는 갈조류는 갈조식물문(褐藻植物門 Phaeophyta)에 속하는 식물로 1,500여 종(種)이 있다. 대륙의 해안을 따라 찬 바닷물에 흔하고 민물에 사는 종은 드물다. 색깔은 갈색색소(푸코산틴)와 녹색색소(클로로필)의 비율에 따라 암갈색에서 황록색까지 다양하다. 가스가 차 있는 주머니[氣泡囊]가 있어 엽상체(葉狀體)의 광합성을 하는 부분이 물표면에 뜨거나 수면 근처에 있게 된다. 갈조류는 모양과 크기가 다양해 엑토카르푸스속(─屬 Ectocarpus) 식물처럼 섬유 모양의 작은 착생식물(着生植物)도 있고, 크기가 1~100m 이상인 다시마속(Laminaria), 마크로키스티스속(Macrocystis), 네로키스티스속(Nerocystis)의 켈프(kelp)라 부르는 종들도 있다. 또한 록위드(rockweed)라고 하는 일부 갈조류는 푸쿠스속(Fucus)이나 아스코필룸속(Ascophyllum) 식물들처럼 온대지방의 바닷가 바위에 붙어 살거나, 모자반속(Sargassum) 식물들처럼 물 위에 떠서 살기도 한다. 갈조류는 무성생식과 유성생식으로 번식하는데, 운동성이 있는 유주자(遊走子)와 배우자는 크기가 서로 다른 편모(鞭毛) 2개를 가지고 있다. 한때 요오드와 탄산칼륨의 주원료로 쓰였으며 지금은 빵과 아이스크림을 만드는 공장에서 점성도를 증가시키기 위해 사용하는 콜로이드상 겔인 알긴의 주원료이다. 어떤 종은 비료로도 쓰이고, 동양에서는 여러 종을 콤부(kombu)라고 하는 야채로 먹는다. 다시마목(─目 Laminariales)의 갈조류는 흔히 켈프라고 부르고 있다. 본 발명에서는 다시마목의 갈조류를 사용하였다.Brown algae used in the present invention is a plant belonging to the brown algae plant (褐藻 植物 門 Phaeophyta), there are about 1,500 species. Common in cold seawater along the coast of the continent, rarely live in freshwater species. The color varies from dark brown to yellow green depending on the ratio of brown (fucoxanthin) to green (chlorophyll). There is a gas-filled bag, so that the photosynthetic part of the frond floats on the surface of the water or near the surface of the water. Brown algae are diverse in shape and size, and have small fibrous plant-like plants like the Ectocarpus plant. Laminaria and Macrocystis are 1-100 m or more in size. There are also species called Kelp of the Nerocystis. Some brown algae, also called rockweed, live on temperate beach rocks like the Fucus or Ascophyllum plants, or float on the water like Sargassum plants. . Brown algae reproduce by asexual reproduction and sexual reproduction, and the motility yogi (遊走 子) and spouses have two different sized flagella. It was once used as the main ingredient for iodine and potassium carbonate, and is now the main ingredient for algin, a colloidal gel used to increase viscosity in bread and ice cream making factories. Some species are used as fertilizers, and in the Orient, several species are eaten as vegetables called kombu. Brown algae of kelp Laminariales are commonly called kelp. In the present invention, seaweed brown algae was used.

본 발의 조성물에 포함되는 천연추출물은 각각의 식물을 물, 유기용매, 또는 이의 혼합용매를 사용하여 추출할 수 있으며, 통상적으로 식물추출물을 얻기위한 영수추출방법을 사용하여 추출된 추출물을 사용하여도 무방하다. 예를 들어, 열수추출의 경우 본 발명에 사용되는 천연물, 즉, 선인장과 갈조류를 물에 가하여 70℃이상, 바람직하게는 80℃ 이상, 보다 바람직하게는 90 ℃이상의 온도에서 2시간 이상 바람직하게는 3시간 이상 가열하고 가열된 혼합물을 여과하여 제조할 수 있다. 이 추출액은 건조하여 사용하거나 추출 상태 그대로 사용할 수 있다. 유기용매를 사용하여 추출하는 경우에는 에탄올, 메탄올 등의 알콜류를 사용하여 실온에서 또는 가온하여 유기 용매로 추출할 수 있다. Natural extracts contained in the composition of the present invention can be extracted each plant using water, an organic solvent, or a mixed solvent thereof, even using an extract extracted using a method of extracting the water to obtain plant extracts in general. It's okay. For example, in the case of hot water extraction, natural products used in the present invention, that is, cactus and brown algae are added to water at 70 ° C. or higher, preferably 80 ° C. or higher, and more preferably 90 ° C. or higher. It may be prepared by heating at least 3 hours and filtering the heated mixture. This extract can be dried or used as it is. When extracting using an organic solvent, alcohols such as ethanol and methanol can be used to extract the organic solvent at room temperature or by heating.

이하, 본 발명의 바람직한 실시예를 들어 보다 상세히 설명하기로 한다. 단, 하기의 실시예로 본 발명을 한정하는 것은 아니다. Hereinafter, a preferred embodiment of the present invention will be described in more detail. However, the present invention is not limited to the following examples.

[실시예 1 내지 2][Examples 1 and 2]

하기의 표 1의 조성으로 이루어지며, 정제수가 채워진 유상탱크에 A상을 투입하여 교반하면서 75℃가온하여 용해한다(조건; Paddele: 3,500rpm, Homo Mixer:2,500 rpm, Time: 5min). 다음, 상기 A상이 용해된 유상탱크에 B상을 투입하 고 70℃로 가온용해(조건; Paddele: 2,500rpm, Homo Mixer:2,500 rpm, Time: 5min)한 후, 45℃로 냉각한다. 상기 A상과 B상의 혼합물에 C상을 넣고 40℃온도에서 용해(조건:Paddele: 2,500rpm, Homo Mixer:2,500 rpm, Time: 10min)한다. 상기 C상이 혼합된 혼합물에 D상을 넣고 천천히 용해(조건:Paddele: 2,000rpm, Homo Mixer:2,500 rpm, Time: 10min)한다. 상기 D상이 혼합된 혼합물에 E상과 F상을 순차적으로 첨가하고 용해(조건:Paddele: 2,500rpm, Time: 10min)하고, 30℃까지 냉각시킨 다음 용해를 멈추고, 여과한 다음 혼합물을 용기에 넣어 겔상으로 제조하였다. It is made up of the composition shown in Table 1, the A phase is added to the oil tank filled with purified water and dissolved by heating to 75 ℃ while stirring (conditions: Paddele: 3,500rpm, Homo Mixer: 2,500rpm, Time: 5min). Next, phase B is added to the oil tank in which phase A is dissolved, and then heated and dissolved at 70 ° C. (conditions; Paddele: 2,500 rpm, Homo Mixer: 2,500 rpm, Time: 5 min), and then cooled to 45 ° C. Phase C is added to the mixture of phase A and phase B and dissolved at 40 ° C. (conditions: Padele: 2,500 rpm, Homo Mixer: 2500 rpm, Time: 10 min). Phase D is added to the mixture of phase C and dissolved slowly (conditions: Padele: 2,000 rpm, Homo Mixer: 2500 rpm, Time: 10 min). Add phase E and phase F sequentially to the mixture of phase D and dissolve (condition: Paddle: 2,500 rpm, Time: 10min), cool to 30 ° C, stop dissolution, filter, and then put the mixture into a container. Prepared in gel form.

Prize 원료명Raw material name 혼합비(단위:중량부)Mixing ratio (unit: parts by weight) 실시예1Example 1 실시예2Example 2 정제수Purified water 100100 100100 AA 하이드록시에틸셀룰로오스Hydroxyethyl cellulose 0.550.55 0.550.55 BB 페녹시에탄올Phenoxyethanol 0.300.30 0.300.30 CC 아데노신Adenosine 0.040.04 0.040.04 히아루론산나트륨Sodium hyaluronate 0.010.01 0.010.01 아세틸 헥사펩타이드-8Acetyl Hexapeptide-8 0.010.01 0.010.01 휴먼 올리고펩타이드-1Human Oligopeptide-1 0.010.01 0.0150.015 DD 씨워터(Sea Water)Sea Water 0.010.01 0.0150.015 EE 선인장추출물Cactus Extract 0.010.01 0.0150.015 FF 갈조류추출물Brown algae extract 0.010.01 0.0150.015

[비교예 1 및 2][Comparative Examples 1 and 2]

상기 표1의 E상과 F상을 제외한 나머지 상을 순차적으로 혼합하여 실시예 1 및 2와 동일한 방법으로 겔상을 제조하였다. The gel phase was prepared in the same manner as in Examples 1 and 2 by sequentially mixing the remaining phases except for the E phase and the F phase of Table 1.

<실험예1: 피부탄력 측정>Experimental Example 1 Measurement of Skin Elasticity

상기 실시예1 및 2에서 제조한 겔상을 피부탄력의 측정을 위하여 온도 24 내지 25℃, 습도 38%정도를 일정하게 유지되는 25 ~ 40세의 건강한 여성 80명을 대상으로 각각 20명씩 군을 나누어 1군에는 상기 실시예1 및 2의 겔을 피검자의 얼굴에 각각 1일 1회씩 3개월 동안 사용하게 하였고, 2군에는 각각 1일 2회, 3군에는 각각 1일 3회 사용하게 하였고, 나머지 20명에게는 비교예 1 및 2에서 제조한 겔상을 각각 1일 3회 사용하게 한 후, Cutometer SEM 474를 이용하여 피부탄력을 측정하였으며, 판정기준은 피부탄력이 없는 경우를 0 많은 경우를 5로 하여 상대적인 값을 비교하였다. 시험결과는 하기 표 2에 나타내었다. 각각의 결과값은 평균값을 나타내었다. The gel phases prepared in Examples 1 and 2 were divided into groups of 80 healthy women of 25 to 40 years of age, which were constantly maintained at a temperature of 24 to 25 ° C. and a humidity of 38% for the measurement of skin elasticity. In the first group, the gels of Examples 1 and 2 were used once a day for 3 months on the face of the subject, and the second group was used twice a day, and the third group was used three times a day, respectively. Twenty subjects were allowed to use the gel phases prepared in Comparative Examples 1 and 2 three times a day, and skin elasticity was measured by using a cutometer SEM 474. Relative values were compared. The test results are shown in Table 2 below. Each result represents an average value.

시험항목Test Items 실시예1Example 1 실시예2Example 2 비교예1Comparative Example 1 비교예2Comparative Example 2 1군Group 1 2군Group 2 3군Group 3 1군Group 1 2군Group 2 3군Group 3 피부탄력도Skin elasticity 2.82.8 3.13.1 3.53.5 3.03.0 3.43.4 3.33.3 1.21.2 1.41.4

상기 표 2의 결과, 본 발명에 따른 천연추출물을 함유한 겔상이 그렇지 아니한 것에 비해 주름개선효과가 훨씬 우수한 것을 알 수 있었다.As a result of Table 2, it was found that the gel phase containing the natural extract according to the present invention has a much better wrinkle improvement effect than it did not.

<실험예2: 사용성 평가>Experimental Example 2: Usability Evaluation

상기 실시예에서 제조한 주름개선용 겔상을 20대-40세까지의 화장을 한 여성 20명의 패널에 대하여 사용중의 피부느낌, 피부자극성, 끈적임, 사용후의 사용감 등에 대하여 조사하였다.The skin feeling, skin irritation, stickiness, and feeling after use of the wrinkle-improving gel phase prepared in the above Example were examined for a panel of 20 women with makeup from 20 to 40 years old.

평가기준은 매우 우수(5점),우수(4점), 보통(3점),나쁨(2점), 매우나쁨(1점)으로 하였으며, 피부자극은 없을 수 록 5점, 심할수록 1점으로 하여 평가하였으며, 끈적임은 적을수록 5점, 심할수록 1점으로 하여 평가하여 이를 하기 수학식 1에 의해 결과를 산출하였다. 그 결과를 표 3에 나타내었다.The evaluation criteria were very good (5 points), excellent (4 points), normal (3 points), bad (2 points), very bad (1 point). It was evaluated as, the less stickiness was evaluated as 5 points, the more severe 1 point to calculate the result by the following equation (1). The results are shown in Table 3.

(수학식1)(Equation 1)

Figure 112009014765556-PAT00001
Figure 112009014765556-PAT00001

평가항목Evaluation item 실시예1Example 1 실시예2Example 2 비교예1Comparative Example 1 비교예2Comparative Example 2 피부느낌Skin feeling 3.953.95 4.04.0 2.952.95 2.952.95 피부자극성Skin irritation 4.24.2 4.14.1 2.752.75 2.82.8 끈적임Sticky 4.054.05 4.354.35 2.72.7 3.03.0 사용감Feeling 4.24.2 4.054.05 2.752.75 2.952.95

위 표 3의 결과, 본 발명에 의해 제조되는 천연추출물을 함유하는 겔상이 천연추출물을 사용하지 않은 것에 비해 사용감이 우수함을 알 수 있었다.As a result of Table 3, it was found that the gel phase containing the natural extract prepared by the present invention has a superior feeling of use compared to the natural extract.

Claims (5)

주름 개선용 기능성 화장품 조성물에 있어서, In the functional cosmetic composition for improving wrinkles, 용제 100 중량부에 대하여 점증제 0.5 ~ 0.6중량부, 방부제 0.2 ~ 0.4 중량부, 스킨컨디셔닝제 0.04 ~ 0.1중량부, 씨워터(See water) 0.005 ~ 0.02 중량부 및 천연추출물 0.01 ~ 0.02 중량부를 혼합하여 되는 것을 특징으로 하는 천연추출물 함유 기능성 주름개선용 조성물.0.5 to 0.6 parts by weight of thickener, 0.2 to 0.4 parts by weight of preservative, 0.04 to 0.1 parts by weight of skin conditioner, 0.005 to 0.02 parts by weight of water and 0.01 to 0.02 parts by weight of natural extract Functional extract for wrinkle-containing composition characterized in that the natural extract. 제 1 항에 있어서, The method of claim 1, 상기 점증제는 하이드록시에틸셀룰로스인 것을 특징으로 하는 천연추출물 함유 기능성 주름개선용 조성물.The thickener is hydroxyethyl cellulose, characterized in that the natural extract containing functional wrinkle improvement composition. 제 1 항에 있어서, The method of claim 1, 상기 방부제는 프로필 파라벤(Propyl Paraben), 부틸 파라벤(Buthyl Paraban), 메틸 파라벤(Methyl Paraben), 페녹시에탄올(Phenoxyethanol) 또는 살리실릭 산(salicylic acid)으로 이루어진 군에서 선택된 1종 또는 2종 이상인 것을 특징으로 하는 천연추출물 함유 기능성 주름개선용 조성물.The preservative is one or two or more selected from the group consisting of propyl paraben, butyl paraben, methyl paraben, methyl paraben, phenoxyethanol, or salicylic acid. Functional extract for wrinkle-containing composition comprising a natural extract. 제 1 항에 있어서, The method of claim 1, 상기 스킨컨디셔닝제는 아데노신, 히아루론산나트륨(Sidium Hyaluronate), 아세틸 헥사펩타이드-8(Acetyl Hexapeptide-8), 휴먼올리고펩타이드-1(Human Oligopeptide-1)으로 이루어진 군에서 선택된 1종 또는 2종 이상의 혼합물인 것을 특징으로 하는 천연추출물 함유 기능성 주름개선용 조성물.The skin conditioning agent is one or a mixture of two or more selected from the group consisting of adenosine, sodium hyaluronate, acetyl hexapeptide-8, and human oligopeptide-1. Natural extract-containing functional wrinkle improvement composition, characterized in that. 제 1 항에 있어서, The method of claim 1, 상기 천연추출물은 선인장 추출물(opuntia ficus-indica Extract), 갈조류 추출물(Fucus Vesiculosus Extract) 또는 이들의 혼합물인 것을 특징으로 하는 천연추출물 함유 기능성 주름개선용 조성물.The natural extract is a cactus extract (opuntia ficus-indica Extract), brown algae extract (Fucus Vesiculosus Extract) or a mixture for the functional extract containing a natural extract, characterized in that a mixture thereof.
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KR101239393B1 (en) * 2011-12-16 2013-03-05 바이허브 주식회사 Cosmetic composition for anti-wrinkle containing natural extract
KR101321854B1 (en) * 2013-07-30 2013-10-28 주식회사 더마랩 Cosmetic composition containing fucus vesiculosus extract and prunella vulgaris extract for improving skin wrinkle and elasticity
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