KR20000018909A - Wrinkle prevention cosmetic composition containing paecilomyces japonica extract - Google Patents

Wrinkle prevention cosmetic composition containing paecilomyces japonica extract Download PDF

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KR20000018909A
KR20000018909A KR1019980036749A KR19980036749A KR20000018909A KR 20000018909 A KR20000018909 A KR 20000018909A KR 1019980036749 A KR1019980036749 A KR 1019980036749A KR 19980036749 A KR19980036749 A KR 19980036749A KR 20000018909 A KR20000018909 A KR 20000018909A
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cosmetic composition
paecilomyces japonica
wrinkle
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skin
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김재진
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김철진
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9728—Fungi, e.g. yeasts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations

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Abstract

PURPOSE: A cosmetic composition is provided which has unexceptional effect in preventing wrinkle with containing extracts of Paecilomyces japonica. CONSTITUTION: In composition, 0.1-20% Paecilomyces japonica in an amount of the entire composition by weight is included. Unlike the existed makes up which cause frequent skin disease, this composition utilizes the strengthening component of immune function inside Paecilomyces japonica to facilitate cell and humoral immunity in case of injecting Paecilomyces japonica extract into the human body. Therefore, immune function is remarkably supplemented to have a high resistant to various tumors and virus infection.

Description

눈꽃동충하초(Ｐａｅｃｉｌｏｍｙｃｅｓ ｊａｐｏｎｉｃａ) 추출물을 함유하는 주름 방지용 화장료 조성물Anti-wrinkle cosmetic composition containing snow cordyceps sinensis (Ｐａｅｃｉｌｏｍｙｃｅｓ ｊａｐｏｎｉｃａ) extract

본 발명은 주름 방지용 화장료 조성물에 관한 것으로, 보다 상세하게는 눈꽃동충하초(Paecilomyces japonica)의 추출물을 함유함으로써 주름의 방지 효과를 갖는 화장료 조성물에 관한 것이다.The present invention relates to a cosmetic composition for preventing wrinkles, and more particularly to a cosmetic composition having an anti-wrinkle effect by containing an extract of Paecilomyces japonica.

고령화 인구가 증가되는 요즈음, 나이를 먹음에 따라 나타나는 여러가지 피부의 고민과 그 대책에 대한 관심은 점차 높아지고 있다. 이러한 관심사중의 하나는, 말할것도 없이 주름이다. 주름에 대하여 지금까지는 화장품의 역할로서 주로 예방측면을 생각해왔다. 그러나, 최근 아크네용 의약품에 의한 주름 개선 효과가 보고된 이래 치료적 성격을 갖는 보다 효과가 높은 항주름 화장품의 개발에 관심이 모아지고 있다.Nowadays, as the aging population increases, interest in various skin concerns and countermeasures that appear with age is increasing. One of these concerns is, of course, wrinkles. As far as wrinkles are concerned, the role of cosmetics has been mainly considered in terms of prevention. However, since the anti-wrinkle effect has recently been reported by the drug for Akne has been attracting attention to the development of more effective anti-wrinkle cosmetics having a therapeutic character.

지금까지 알려진 항주름제는 건조한 피부를 촉촉하게 하여 건조한 피부에 부수되는 각화의 이상이 정상으로 회복되어 주름을 개선시켜 주는 보습제 형태, 콜라겐 생합성을 증가시켜 피부의 탄력을 증진시켜 피부의 주름을 개선시키는 물질, 항산화 효과를 갖는 물질 및 경피수분증발을 억제시키는 물질들이다. 항주름 효과를 갖는 보습제로서 주로 사용되고 있는 것으로는 히아루론산 또는 소듐콘드로이틴 설페이트를 들 수 있고, 또 의약품에 많이 사용되고 있는 레티노이드산도 항주름 효과가 우수한 것으로 알려져 있다. 그러나, 레티노이드산은 사용시에 피부가 붉어지고, 비늘이 생기며, 자외선에 의한 민감성 반응을 나타내는 부작용 등이 보고되어 있고 6개월이상 계속 사용하여야만 효과가 나타나는 문제점이 있다. 또한, 항주름 효과면에서 레티노이드산과 유사한 효과를 나타내는 알파히드록시애씨드가 항주름제로 공지되어 있으나, 주름방지 또는 개선의 효과를 가지기 위해서는 다량(1.0∼10%)사용하여야 하고, 따라서, 가려움, 홍반, 피부이상 각질현상 등의 피부자극이라는 부작용을 수반하게 되어 화장품이 추구하는 제품의 안전성 측면을 만족시킬 수 없어 화장품으로서의 가치를 떨어뜨릴 수 밖에 없는 문제점이 있다.The anti-wrinkle agent known to moisturize dry skin to restore the normalization of keratin accompanying dry skin to normal, improves wrinkles and improves wrinkles by increasing collagen biosynthesis to improve skin elasticity And substances that inhibit antioxidants and those that inhibit transdermal moisture evaporation. Examples of the moisturizing agent having an anti-wrinkle effect include hyaluronic acid or sodium chondroitin sulfate. Retinoid acid, which is widely used in medicines, is also known to have excellent anti-wrinkle effect. However, retinoid acid has a problem that redness, scales, and side effects indicating a sensitive reaction caused by ultraviolet light have been reported when used, and the effect should be continued for 6 months or longer. In addition, alpha hydroxy acid, which has a similar effect to retinoid acid in terms of anti-wrinkle effect, is known as an anti-wrinkle agent, but in order to have an effect of preventing or improving wrinkles, a large amount (1.0 to 10%) should be used, and therefore, itching and erythema It is accompanied by side effects such as skin irritation such as skin abnormalities keratin phenomenon can not satisfy the safety aspect of the product pursued by cosmetics, there is a problem that can not only deteriorate the value as cosmetics.

이에, 본 발명자들은 보다 피부에의 자극이 없고 효과적인 항주름 작용을 나타내는 화장료를 제공하고자 예의연구한 결과, 항암효과 또는 활성산소에 의해 일어나는 심장질환이나 뇌질환치료 효과가 있는 물질로 공지된 눈꽃동충하초(Paecilomyces japonica)의 추출물을 함유하므로써 상기 목적을 달성할 수 있음을 발견하고 본 발명을 완성하기에 이르렀다.Accordingly, the present inventors have studied diligently to provide a cosmetic that exhibits an effective anti-wrinkle effect without irritation to the skin, and as a result, the snowfly is known as a substance having a therapeutic effect on heart disease or brain disease caused by an anticancer effect or active oxygen. It was found that the above object can be achieved by containing an extract of Paecilomyces japonica, and thus, the present invention has been completed.

따라서, 본 발명의 목적은 주름 방지용 화장료 조성물을 제공하는 것이다.Accordingly, it is an object of the present invention to provide a cosmetic composition for preventing wrinkles.

상기한 목적을 달성하기 위하여, 본 발명의 주름 방지용 화장료 조성물은 눈꽃동충하초(Paecilomyces japonica) 추출물을 조성물 총 중량에 대하여 0.1∼20.0중량%의 양으로 함유함을 특징으로 한다.In order to achieve the above object, the anti-wrinkle cosmetic composition of the present invention is characterized by containing an extract of Paecilomyces japonica in an amount of 0.1 to 20.0% by weight based on the total weight of the composition.

상기한 본 발명의 목적, 그외의 목적, 특징 및 장점은 하기 발명의 상세한 설명으로부터 당업자에게 명백하게 드러날 것이다.The above and other objects, features and advantages of the present invention will become apparent to those skilled in the art from the following detailed description.

이하, 본 발명을 보다 상세하게 설명한다.Hereinafter, the present invention will be described in more detail.

동충하초는 사상균의 일종인 동충하초균이 곤충에 감염되어 나온 일종의 약용버섯으로서 중국, 네팔, 일본, 남아메리카, 대한민국 등에 자생하는 것으로 알려져 있다. 동충하초의 감염경로는 주로 분생포자가 비산하여 곤충표피에 부착함으로써 이루어지는 경피 감염에 의존하고 있으며, 포자가 표피에 부착된 후 적당한 온도·습도 등의 조건을 만나게 되면 발아하여 곤충의 표피를 뚫고 들어가 체내에서 균사상태로 발육증식하다가, 곤충이 죽은 후에는 체내의 균사가 기주곤충의 표피위에 자실체를 형성하게 된다. 자실체는 병부와 선단의 결실부로 구성된 1.5∼10㎝ 크기의 사상, 곤봉상, 원통상 등의 모양을 형성하며 색상은 백색, 흑색, 적색, 갈색 등 여러 가지로서 동충하초 종별로 다양하다.Cordyceps sinensis is a kind of medicinal mushroom from which fungus Cordyceps sinus is infected with insects and is known to grow native to China, Nepal, Japan, South America and Korea. The path of infection of cordyceps relies mainly on transdermal infection caused by conidia scattering and attaching to the insect epidermis.When spores adhere to the epidermis and meet conditions such as temperature and humidity, they germinate and penetrate the epidermis of the insect. In the mycelial growth of the larvae, after the death of the insect mycelium will form fruiting bodies on the epidermis of host insects. Fruiting body forms a shape of 1.5 ~ 10cm sized filamentous, club-shaped, cylindrical, etc., consisting of a diseased part and a distal end, and various colors such as white, black, red, and brown.

상기에서와 같은 생리 생태적인 특성을 가진 동충하초는 여러 가지 질병에 대한 약리적 효능 때문에 오늘날 많은 관심과 연구의 대상이 되고 있다.Cordyceps sinensis, which has the same physiological and ecological characteristics as above, has been the subject of much interest and research today because of its pharmacological effects on various diseases.

그 예로써, 중국에서는 예로부터 동충하초가 불로장생의 비약으로 널리 알려져 있을 뿐만 아니라 폐를 보호하고 신장을 튼튼하게 하는 등의 효능을 내는 귀중한 약재로 선호되어 왔고, 중국의 고의서인 "증류본초"에는 용충초, 아향봉충초 등 여러 종의 동충하초가 종별로 다양하게 광범위한 질병에 효능을 내는 것으로 기록되어 있다. 또한, 일본의 경우 1801년 "본초서"에 동충하초에 대한 기록이 전해지고 있는 바, 당시 폐병이나 늑막염의 특효약으로 판매되기도 하였다. 그리고, 중국, 일본 등의 최근 연구결과에 의하면 동충하초에는 면역 기능을 강화시키는 성분이 함유되어 있어 동충하초 추출물을 인체에 투여할 경우 세포면역과 체액면역을 촉진시킴으로써 면역기능을 현저히 보강시켜 각종 종양과 바이러스 감염에 대한 저항력을 높이는 등의 효과가 있는 것으로 나타났다.For example, in China, Cordyceps sinensis has long been widely known as a elixir of firemen and has been favored as a valuable medicine for protecting the lungs and strengthening the kidneys. Cordyceps sinensis such as Choongcho and Azibongbongchocho have been reported to be effective in a wide range of diseases by species. In addition, in Japan, records of Cordyceps sinensis were reported in 1801, "Bonchoseo", which was sold as a special medicine for lung disease and pleurisy at that time. In addition, according to recent studies in China and Japan, Cordyceps sinensis contains components that enhance immune function. When Cordyceps sinensis extract is administered to the human body, it significantly enhances immune function by promoting cellular immunity and humoral immunity. It has been shown to increase the resistance to infection.

이런 여러 가지 효능을 나타내는 동충하초는 세계적으로 300여종이 분포하고 있고 많은 수의 종이 서로 상이한 효능을 나타내는 것으로 알려지고 있어 천연의약품의 원료로 많은 기대를 모으고 있다. 예를 들면, 불로장생 및 강정강장의 비약으로 사용되어온 코디셉스속(Cordyceps sp.) 동충하초는 기관지확장, 진정, 항균, 평활근억제 등의 약리작용을 갖고 있으며(한약규격집 주해), 항암효과(일약약품, 한국특허공고 제 93-2831호)와 면역활성용 식품원료(곤도 등, USP 5603937; 린칭양, USP 5582828), 이러한 효능을 활용한 음료(조선무약, 한국특허 공개 제 97-68912호)등의 특허가 소개되었다.Cordyceps sinensis, which exhibits these various effects, is distributed around the world, and a large number of species are known to show different effects from each other. For example, Cordyceps sp. Cordyceps, which has been used as a drug for bully and gangjeonggang, has pharmacological effects such as bronchodilation, sedation, antibacterial and smooth muscle suppression (Huyang Drug Commentary), anticancer effect , Korean Patent Publication No. 93-2831) and foodstuffs for immune activation (Kondo et al., USP 5603937; Linqing Yang, USP 5582828), beverages utilizing these effects (Chosun Pharmaceuticals, Korean Patent Publication No. 97-68912), etc. Patents have been introduced.

그러나, 본원 발명에서 사용된 동충하초는 눈꽃동충하초(Paecilomyces japonica)로서, 이 동충하초는 종래 폴리갈락토사민의 항암효과(Ishitani et al., J. Paarmacobiodyn., 11, 58, 1988; Higeta Shoyu, 일본공개특허 05-320203호), 사이토핀(saintopin, 교와하꼬, 국제특허공개 제 94012458호), 파르네실 트랜스퍼라제(farnesyl transferase) 효소의 억제제로 쿠라소인(kurasoin; 기타사토, 일본공개특허 08-239339호) 등 주로 항암효과를 갖음이 공지되어 있고, 활성산소에 의해 일어나는 심장질환이나 뇌질환 치료제로 히드록시알콕시벤조퓨란 유도체(후지사와제약, 유럽특허공개 제 398142호)가 페실로마이세스속 균주 F-1818826의 발효물로부터 추출된 것이라는 것이 공지되어 있다.However, the Cordyceps sinensis used in the present invention is Paecilomyces japonica, which is an anticancer effect of the conventional polygalactosamine (Ishitani et al., J. Paarmacobiodyn., 11, 58, 1988; Higeta Shoyu, published in Japan). Patent 05-320203), cytokin (saintopin, Kyowahako, International Patent Publication No. 94012458), kurasoin (Kurasoin; Kitasato, Japan Patent Publication 08-239339) as an inhibitor of farnesyl transferase enzyme Hydroxyalkoxybenzofuran derivatives (Fujisawa Pharmaceutical, European Patent Publication No. 398142) are used for treating heart disease or brain disease caused by active oxygen. It is known that it is extracted from the fermentation of -1818826.

그러나, 본원 발명에서 목적하는 항주름 효과에 대해서는 개시되어 있는 바가 없다.However, the anti-wrinkle effect desired in the present invention is not disclosed.

본 발명에서 사용된 눈꽃동충하초는 농촌진흥청 잠사곤충연구소에서 눈꽃동충하초균주를 누에에 감염시켜 대량생산하는 방법[대한민국특허공개 제 1998-23907호(1998. 07. 06)]을 개발하여 전국 농촌에 보급, 생산하고 있는 것이다.Snowflower Cordyceps used in the present invention developed a method for mass production by infecting Snowflower Cordyceps strains with silkworms at the Provincial Insect Research Institute of Rural Development Administration [Korea Patent Publication No. 1998-23907 (1998. 07. 06)] To produce.

눈꽃동충하초 추출물은 눈꽃동충하초 약 25g에 1,3-부탄디올 25g, 에탄올 10g 및 증류수 40g을 혼합하고, 실온에서 2일간 교반한 다음, 여과하여 제조한다.Snow Cordyceps sinensis extract is prepared by mixing 25 g of 1,3-butanediol, 10 g of ethanol and 40 g of distilled water in about 25 g of Snow Cordyceps sinensis, stirring at room temperature for 2 days, and then filtering.

본 발명의 주름방지 화장료 조성물은 상기 눈꽃동충하초 추출물을 조성물 총 중량에 대하여 0.1∼20.0중량%의 양으로 함유한다.The anti-wrinkle cosmetic composition of the present invention contains the snow Cordyceps sinensis extract in an amount of 0.1 to 20.0% by weight based on the total weight of the composition.

본 발명의 주름 방지용 화장료 조성물은 그 제형에 있어서 특별히 한정되는 바가 없으며, 예를 들면, 스킨, 로션, 영양크림, 마사지 크림, 에센스, 아이크림, 아이에센스 등의 화장료로 제형화될 수 있다.The anti-wrinkle cosmetic composition of the present invention is not particularly limited in the formulation, for example, may be formulated into a cosmetic such as skin, lotion, nutrition cream, massage cream, essence, eye cream, eye essence.

또한, 각 제형의 주름 방지용 화장료 조성물에 있어서, 상기한 눈꽃동충하초 추출물 이외의 성분들은 기타 화장료의 제형 또는 사용목적 등에 따라 당업자가 어려움없이 적의 선정하여 배합할 수 있다.In addition, in the cosmetic composition for anti-wrinkle of each formulation, components other than the above-mentioned snow Cordyceps sinensis extract can be selected and blended by those skilled in the art without difficulty according to the formulation or purpose of use of other cosmetics.

이하, 본 발명의 실시예를 들어 본 발명의 구성 및 그 효과에 대하여 보다 구체적으로 설명한다.EMBODIMENT OF THE INVENTION Hereinafter, the structure of this invention and its effect are demonstrated in more detail, based on the Example of this invention.

실시예 1 및 비교예 1; 에센스Example 1 and Comparative Example 1; essence

성분ingredient 실시예 1Example 1 비교예 1Comparative Example 1 1) 글리세린1) Glycerin 22.022.0 22.022.0 2) 소듐히아루로네이트2) sodium hyaluronate 3.03.0 3.03.0 3) 알란토인3) allantoin 0.10.1 0.10.1 4) 에틸렌디아민테트라초산나트륨4) Sodium Ethylenediaminetetraacetate 0.010.01 0.010.01 5) 폴리에틸렌글리콜 15005) polyethylene glycol 1500 2.02.0 2.02.0 6) α-세라미드6) α-ceramide 0.50.5 0.50.5 7) 판테놀7) Panthenol 0.10.1 0.10.1 8) 눈꽃동충하초 추출물8) Snow Cordyceps Sinensis Extract 10.010.0 -- 9) 카르복시비닐폴리머9) Carboxyvinyl Polymer 0.150.15 0.150.15 10) 이미다졸리디닐우레아10) imidazolidinylurea 0.20.2 0.20.2 11) 에탄올11) ethanol 6.06.0 6.06.0 12) 파라옥시안식향산메틸12) methyl paraoxybenzoate 0.10.1 0.10.1 13) 폴리에칠렌경화피마자유13) Polyester Cured Castor Oil 0.10.1 0.10.1 14) 향료14) spices 0.10.1 0.10.1 15) 트리에탄올아민15) Triethanolamine 0.150.15 0.150.15 16) 정제수16) purified water to 100to 100 to 100to 100

[제조방법][Manufacturing method]

1. 원료 16)에 원료 9)를 분산시킨 후, 여기에 원료 1∼8을 혼합하여 수상으로 하였다.1. After dispersing the raw material 9) into the raw material 16), the raw materials 1 to 8 were mixed therein to obtain an aqueous phase.

2. 상기 수상에 원료 10)을 넣고, 혼합하였다.2. The raw material 10) was put into the said water phase, and it mixed.

3. 원료 11)에 원료 12∼14를 용해시킨 것을 알코올상으로 하였다.3. What melt | dissolved raw materials 12-14 in the raw material 11) was made into alcohol.

4. 상기 알코올상을 수상에 교반하면서 서서히 가하고, 여기에 원료 15)를 혼합하였다.4. The alcohol phase was gradually added to the water phase with stirring, and raw material 15) was mixed therein.

〈시험예 1〉<Test Example 1>

본 발명에 따른 화장료 조성물의 각종 효과를 알아보기 위하여, 실시예 1 및 비교예 1의 에센스를 시료로 이용하여 피부에 사용하고 각종 효과를 평가하였다.In order to examine the various effects of the cosmetic composition according to the present invention, the essences of Example 1 and Comparative Example 1 were used as a sample and used on the skin to evaluate various effects.

<평가방법><Evaluation Method>

25∼40세 연령의 여성 100명을 대상으로 안면 좌부에는 실시예 1을, 우부에는 비교예 1을 2주간 아침 및 저녁으로 깨끗하게 세안한 얼굴에 사용하게 한 후, 주름방지에 있어서 현저한 효과가 있는 경우 5점으로, 전혀 효과 없는 경우를 0점으로 하여 6단계로 평가하게 하고 평균을 내었다. 한편 피부자극은 얼굴에 홍반, 가려움, 비늘이 형성되는 지의 여부에 대하여 전혀 자극이 없는 경우 0점으로, 자극이 심한 경우를 5점으로 하여 각 6단계로 평가하게 하였다.100 women aged 25 to 40 years of age were treated with Example 1 on the left side of the face and Comparative Example 1 on the right side for two weeks in the morning and evening. Case 5 was evaluated, and the case of no effect at 0 was evaluated in 6 stages and averaged. On the other hand, skin irritation was evaluated in each of six stages, with 0 points for no irritation and 5 points for severe irritation for erythema, itching, and scales on the face.

시료명Sample name 비교예 1Comparative Example 1 실시예 1Example 1 항주름 효과Anti-wrinkle effect 1.21.2 4.74.7 피부자극 효과Skin irritation effect 0.00.0 0.00.0

이상의 실험결과에서 알 수 있듯이, 본 발명에서와 같이 눈꽃동충하초 추출물을 함유하는 화장료 조성물은 그의 주름방지효과 및 피부 안전성면에서 아주 우수하다.As can be seen from the above experimental results, as in the present invention, the cosmetic composition containing the Snow Cordyceps sinensis extract is very excellent in its anti-wrinkle effect and skin safety.

〈시험예 2〉 피부주름 개선효과<Test Example 2> Skin wrinkle improvement

35∼45세의 안면주름이 있는 시험대상자 30명에 대하여, 상기 실시예 1과 비교예 1의 에센스에 대하여 피부주름 개선효과를 비교평가하게 하였다.Thirty-five subjects with facial wrinkles aged 35 to 45 years were compared and evaluated for improving skin wrinkles with respect to the essences of Example 1 and Comparative Example 1.

피검자의 안면 좌부에는 실시예 1을, 우부에는 비교예 1을 3개월간 사용하도록 하였다. 에센스사용 이전의 안면 양쪽부의 피부상태를 측정해 놓은 후 에센스사용 3개월 후 동일부위를 재측정하여 피부주름의 변화를 측정하였다. 피부측정은 24℃ 온도, 상대습도 40%의 항온항습실에서 하였으며, 눈꼬리부위의 주름을 레플리카(replica)로 떠서 비시오메타 시스템(Visiometer system; C+K사)으로 피부주름을 측정하였다. 피부주름의 변화량은 하기 수학식 1에 따라 계산하였다.Example 1 was used for the face left part of the subject, and Comparative Example 1 was used for the right part for 3 months. After measuring the skin condition on both sides of the face before essence use, three months after essence use, the same area was remeasured to measure changes in skin wrinkles. Skin measurement was performed in a constant temperature and humidity room with a temperature of 24 ° C. and a relative humidity of 40%. The wrinkles at the tail of the eyes were replicated, and skin wrinkles were measured using a Visiometer system (C + K). The amount of change in skin wrinkles was calculated according to Equation 1 below.

(상기 식에서, Tdi; D90에서의 측정부위 값이며, Tdo; D0에서의 측정부위 값이다)Where Tdi is the measured value at D 90 and Tdo is the measured value at D 0 .

상기 식에 따라 계산한 결과, 비교예 1을 사용한 부위의 피부주름은 7±5%(평균±표준편차)의 감소치를 나타낸 반면, 실시예 1을 사용한 부위의 피부주름은24±10%의 감소치를 보여 우수한 피부주름 개선효과를 나타내었다.As a result of calculation according to the above formula, the skin wrinkle at the site using Comparative Example 1 showed a decrease of 7 ± 5% (mean ± standard deviation), whereas the skin wrinkle at the site using Example 1 was reduced to 24 ± 10%. To improve skin wrinkles.

이하, 상기한 시험예들의 결과를 근거로 하여, 눈꽃동충하초 추출물을 함유함으로써 피부 주름 방지 효과를 제공할 수 있는 여러 제형의 화장료를 조성하여 제시한다. 그러나 본 발명의 조성물이 하기의 제형예에 한정되는 것은 아니다.Hereinafter, on the basis of the results of the above test examples, by presenting a cosmetic composition of the various formulations that can provide a skin wrinkle prevention effect by containing a snow Cordyceps sinensis extract. However, the composition of the present invention is not limited to the following formulation example.

실시예 2. 스킨Example 2. Skin

성분ingredient 중량%weight% 눈꽃동충하초 추출물Snow Cordyceps Sinensis Extract 3.03.0 부틸렌글리콜Butylene glycol 3.03.0 글리세린glycerin 2.02.0 알란토인Allantoin 0.10.1 소듐히아루로네이트Sodium hyaluronate 1.01.0 에틸렌디아민테트라초산디나트륨Ethylenediaminetetraacetate acetate 0.010.01 α-세라미드α-ceramide 0.10.1 폴리에틸렌글리콜 1500Polyethylene Glycol 1500 2.02.0 에탄올ethanol 6.06.0 파라옥시안식향산메틸Methyl paraoxybenzoate 0.010.01 폴리옥시에틸렌경화피마자유Polyoxyethylene Cured Castor Oil 0.10.1 향료Spices 0.10.1 정제수Purified water to 100to 100

실시예 3. 크림Example 3. Cream

성분ingredient 중량%weight% 눈꽃동충하초 추출물Snow Cordyceps Sinensis Extract 5.05.0 세토스테아릴알코올Cetostearyl alcohol 2.02.0 스테아린산Stearic acid 1.71.7 자기유화형모노스테아린산글리세린Self-emulsifying monoglycerate glycerin 1.51.5 친유형모노스테아린산글리세린Lipophilic Monostearic Acid Glycerin 1.51.5 마이크로크리스탈린납Microcrystalline Lead 0.80.8 밀납Beeswax 0.80.8 세스퀴올레인산소르비탄Sesquioleate sorbitan 0.50.5 폴리옥시에틸렌소르비탄모노스테아레이트Polyoxyethylene sorbitan monostearate 1.21.2 파라옥시안식향산메틸Methyl paraoxybenzoate 0.20.2 파라옥시안식향산프로필Paraoxybenzoic acid propyl 0.10.1 디메치콘Dimethicone 0.20.2 세틸옥타노에이트Cetyloctanoate 2.02.0 트리(카프릴, 카프릴산)글리세린Tri (capryl, caprylic acid) glycerin 3.03.0 스쿠알란Squalane 2.02.0 유동파라핀Liquid paraffin 5.05.0 트리에탄올아민Triethanolamine 0.10.1 부틸렌글리콜Butylene glycol 4.04.0 글리세린glycerin 4.04.0 알란토인Allantoin 0.10.1 에틸렌디아민테트라초산디나트륨Ethylenediaminetetraacetate acetate 0.010.01 소듐히아루로네이트Sodium hyaluronate 2.02.0 α-세라미드α-ceramide 0.50.5 향료Spices 0.10.1 이미졸리디닐우레아Imidolidinylurea 0.20.2 정제수Purified water to 100to 100

실시예 4. 로션Example 4 Lotion

성분ingredient 중량%weight% 눈꽃동충하초 추출물Snow Cordyceps Sinensis Extract 3.03.0 세토스테아릴알코올Cetostearyl alcohol 2.52.5 스테아린산Stearic acid 1.71.7 마이크로크리스탈린납Microcrystalline Lead 0.80.8 밀납Beeswax 0.50.5 자기유화형모노스테아린산글리세린Self-emulsifying monoglycerate glycerin 1.21.2 친유형모노스테아린산글리세린Lipophilic Monostearic Acid Glycerin 0.80.8 세스퀴올레인산소르비탄Sesquioleate sorbitan 0.50.5 폴리옥시에틸렌소르비탄모노스테아레이트Polyoxyethylene sorbitan monostearate 1.21.2 파라옥시안식향산메칠Paraoxybenzoic Acid Methyl 0.20.2 파라옥시안식향산프로필Paraoxybenzoic acid propyl 0.10.1 디메치콘Dimethicone 0.20.2 세틸옥타노에이트Cetyloctanoate 1.01.0 스쿠알란Squalane 2.02.0 트리(카프릴, 카프릴산)글리세린Tri (capryl, caprylic acid) glycerin 3.03.0 유동파라핀Liquid paraffin 5.05.0 트리에탄올아민Triethanolamine 0.20.2 부틸렌글리콜Butylene glycol 3.03.0 글리세린glycerin 5.05.0 에틸렌디아민테트라초산디나트륨Ethylenediaminetetraacetate acetate 0.010.01 알란토인Allantoin 0.10.1 소듐히아루노네이트Sodium hyalonate 1.01.0 α-세라미드α-ceramide 0.50.5 카르복시비닐폴리머Carboxy Vinyl Polymer 0.130.13 향료Spices 0.10.1 이미졸리디닐우레아Imidolidinylurea 0.20.2 정제수Purified water to 100to 100

이상에서 설명한 바와 같이, 눈꽃동충하초(Paecilomyces japonica)의 추출물을 함유시킴으로써 주름방지에 우수한 화장료 조성물을 제공할 수 있다.As described above, by containing the extract of Paecilomyces japonica can provide a cosmetic composition excellent in the prevention of wrinkles.

Claims (1)

주름 방지용 화장료 조성물에 있어서, 눈꽃동충하초(Paecilomyces japonica)를 1,3-부탄디올, 에탄올 및 증류수와 혼합한 후, 실온에서 2일간 교반하고 여과하여 제조한 눈꽃동충하초의 추출물을 조성물 총 중량에 대하여 0.1∼20.0중량%의 양으로 함유함을 특징으로 하는 주름 방지용 화장료 조성물.In the cosmetic composition for preventing wrinkles, Paecilomyces japonica is mixed with 1,3-butanediol, ethanol and distilled water, and then stirred for 2 days at room temperature and filtered to extract an extract of Snow Cordyceps sinensis against the total weight of the composition. A cosmetic composition for preventing wrinkles, comprising in an amount of 20.0% by weight.
KR1019980036749A 1998-09-07 1998-09-07 Anti-wrinkle cosmetic composition containing PAECILOMYCES JAPONICA extract KR100340185B1 (en)

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