KR102759903B1 - 클로로프로카인의 국소 제형 및 이의 사용 방법 - Google Patents

클로로프로카인의 국소 제형 및 이의 사용 방법 Download PDF

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Publication number
KR102759903B1
KR102759903B1 KR1020207004474A KR20207004474A KR102759903B1 KR 102759903 B1 KR102759903 B1 KR 102759903B1 KR 1020207004474 A KR1020207004474 A KR 1020207004474A KR 20207004474 A KR20207004474 A KR 20207004474A KR 102759903 B1 KR102759903 B1 KR 102759903B1
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KR
South Korea
Prior art keywords
formulation
chloroprocaine
hydroxyethyl cellulose
amount
hydrochloric acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
KR1020207004474A
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English (en)
Korean (ko)
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KR20200053476A (ko
Inventor
아우구스토 미티디에리
엘리사베타 도나티
클라라 비안치
Original Assignee
신테티카 에스에이
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Publication date
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Publication of KR20200053476A publication Critical patent/KR20200053476A/ko
Application granted granted Critical
Publication of KR102759903B1 publication Critical patent/KR102759903B1/ko
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A61K31/245—Amino benzoic acid types, e.g. procaine, novocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Anesthesiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Ophthalmology & Optometry (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020207004474A 2017-09-15 2018-09-14 클로로프로카인의 국소 제형 및 이의 사용 방법 Active KR102759903B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762559220P 2017-09-15 2017-09-15
US62/559,220 2017-09-15
PCT/IB2018/057073 WO2019053657A1 (en) 2017-09-15 2018-09-14 TOPICAL FORMULATIONS OF CHLOROPROCAINE

Publications (2)

Publication Number Publication Date
KR20200053476A KR20200053476A (ko) 2020-05-18
KR102759903B1 true KR102759903B1 (ko) 2025-01-23

Family

ID=63713967

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020207004474A Active KR102759903B1 (ko) 2017-09-15 2018-09-14 클로로프로카인의 국소 제형 및 이의 사용 방법

Country Status (22)

Country Link
US (3) US10792271B2 (https=)
EP (1) EP3681473A1 (https=)
JP (1) JP2020533321A (https=)
KR (1) KR102759903B1 (https=)
CN (1) CN111163756B (https=)
AU (1) AU2018332212B2 (https=)
CA (1) CA3070336C (https=)
CL (1) CL2020000665A1 (https=)
CO (1) CO2020002985A2 (https=)
CR (1) CR20200133A (https=)
CU (1) CU20200019A7 (https=)
EA (1) EA202090735A1 (https=)
EC (1) ECSP20022313A (https=)
IL (1) IL273213B2 (https=)
JO (1) JOP20200010A1 (https=)
MA (1) MA50241A (https=)
MX (1) MX2020002898A (https=)
PE (1) PE20201281A1 (https=)
PH (1) PH12020550029A1 (https=)
SG (1) SG11202000992RA (https=)
WO (1) WO2019053657A1 (https=)
ZA (1) ZA202000601B (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW202139993A (zh) * 2020-03-16 2021-11-01 瑞士商辛鐵堤卡公司 具有經改良之功能性的眼用氯普魯卡因(chloroprocaine)凝膠

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR930000050B1 (ko) * 1990-08-29 1993-01-06 브리스톨-마이어즈 스퀴브 컴페니 항균제 겔 배합물
US6218428B1 (en) * 2000-04-28 2001-04-17 Emil Chynn Ophthalmic composition
JP2004123634A (ja) * 2002-10-03 2004-04-22 Lion Corp 眼科用組成物
WO2004058329A2 (en) * 2002-12-20 2004-07-15 The Board Of Trustees Of The Leland Stanford Junior University Ester combination local anesthetic
US20050137177A1 (en) 2003-12-18 2005-06-23 Shafer Steven L. Ester combination local anesthetic
EA200701131A1 (ru) * 2004-11-24 2007-12-28 Алгоркс Фармасьютикалз, Инк. Гелеобразная препаративная форма капсаициноида и способы её применения
ITMI20051633A1 (it) 2005-09-06 2007-03-07 Sint Sa Nuovo uso di una composizione comprendente cloroprocaina hcl nuova composizione comprendente cloroprocaina hcl e metodo per la sua fabbricazione
ITMI20122120A1 (it) * 2012-12-12 2014-06-13 Sint Sa Composizione farmaceutica a base di cloroprocaina per la somministrazione intratecale ripetuta
CN103405576B (zh) * 2013-08-23 2016-03-30 何学忠 一种治疗由焊接强光辐射引起的眼部疾病的滴眼液

Also Published As

Publication number Publication date
EP3681473A1 (en) 2020-07-22
JP2020533321A (ja) 2020-11-19
IL273213B2 (en) 2025-06-01
IL273213B1 (en) 2025-02-01
KR20200053476A (ko) 2020-05-18
AU2018332212A1 (en) 2020-02-27
MX2020002898A (es) 2020-11-06
CA3070336C (en) 2022-08-23
CU20200019A7 (es) 2020-11-30
WO2019053657A1 (en) 2019-03-21
IL273213A (en) 2020-04-30
AU2018332212B2 (en) 2023-03-16
US11969403B2 (en) 2024-04-30
EA202090735A1 (ru) 2020-06-22
US20190083446A1 (en) 2019-03-21
US10792271B2 (en) 2020-10-06
BR112020003095A2 (pt) 2020-08-25
CL2020000665A1 (es) 2020-09-21
SG11202000992RA (en) 2020-03-30
JOP20200010A1 (ar) 2020-01-22
CA3070336A1 (en) 2019-03-21
CN111163756A (zh) 2020-05-15
ZA202000601B (en) 2021-02-24
PH12020550029A1 (en) 2021-02-08
CO2020002985A2 (es) 2020-05-29
ECSP20022313A (es) 2020-07-31
CN111163756B (zh) 2022-04-15
US20200390738A1 (en) 2020-12-17
US20240216323A1 (en) 2024-07-04
MA50241A (fr) 2020-07-22
CR20200133A (es) 2020-05-09
PE20201281A1 (es) 2020-11-24

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