KR102615005B1 - 수불용성 또는 난수용성 약물의 수성 용해도를 개선시키기 위한 방법 - Google Patents

수불용성 또는 난수용성 약물의 수성 용해도를 개선시키기 위한 방법 Download PDF

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KR102615005B1
KR102615005B1 KR1020187004268A KR20187004268A KR102615005B1 KR 102615005 B1 KR102615005 B1 KR 102615005B1 KR 1020187004268 A KR1020187004268 A KR 1020187004268A KR 20187004268 A KR20187004268 A KR 20187004268A KR 102615005 B1 KR102615005 B1 KR 102615005B1
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water
concentration
dexpanthenol
aqueous solvent
dissolved
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KR20180054569A (ko
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안드레아스 그라쏘어
에바 프리슐-그라쏘어
안젤리카 보덴타이흐
마르티나 모로쿠티-쿠르츠
사비네 나코비치
코르넬리아 카인츠
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마리노메드 바이오테크 아게
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    • A61K9/08—Solutions
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
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    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
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    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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KR1020187004268A 2015-07-16 2016-07-15 수불용성 또는 난수용성 약물의 수성 용해도를 개선시키기 위한 방법 Active KR102615005B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201514801578A 2015-07-16 2015-07-16
US14/801,578 2015-07-16
PCT/EP2016/066999 WO2017009480A1 (en) 2015-07-16 2016-07-15 Method for improving aqueous solubility of water-insoluble or slightly water-soluble drugs

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KR20180054569A KR20180054569A (ko) 2018-05-24
KR102615005B1 true KR102615005B1 (ko) 2023-12-18

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EP (1) EP3324933B1 (https=)
JP (1) JP6836825B2 (https=)
KR (1) KR102615005B1 (https=)
CN (1) CN107847440B (https=)
AU (1) AU2016293125B2 (https=)
CA (1) CA2992376C (https=)
CL (1) CL2018000032A1 (https=)
CO (1) CO2018001460A2 (https=)
CY (1) CY1124322T1 (https=)
DK (1) DK3324933T3 (https=)
EA (1) EA036233B1 (https=)
ES (1) ES2844581T3 (https=)
HR (1) HRP20210333T1 (https=)
HU (1) HUE053116T2 (https=)
IL (1) IL256882B (https=)
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MA (1) MA42472B1 (https=)
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NZ (1) NZ738592A (https=)
PH (1) PH12018500042A1 (https=)
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CN108143713A (zh) * 2018-01-04 2018-06-12 南方医科大学南方医院 一种增加羟喜树碱溶解度的方法
US12377046B1 (en) 2019-04-24 2025-08-05 Wellomics LLC Delivery system matrices
CN110074385B (zh) * 2019-05-21 2022-05-31 绥化市蓝源生物工程有限公司 一种生物碱溶解纳他霉素的生物溶剂及其应用
KR20220022829A (ko) * 2020-08-19 2022-02-28 주식회사 모든바이오 글리시리진 및 수용성 약물을 포함하는 나노 입자, 이를 포함하는 약제학적 조성물 및 이들의 제조 방법
CN114588118B (zh) * 2022-01-25 2023-05-23 武汉爱民制药股份有限公司 一种注射用七叶皂苷钠复方制剂
KR102922176B1 (ko) * 2022-07-08 2026-02-04 한국생산기술연구원 소수성 약물 전달을 위한 금-히알루론산 나노입자의 제조방법
EP4431082A1 (en) * 2023-03-13 2024-09-18 Marinomed Biotech AG Aqueous composition comprising budesonide
EP4516289A1 (en) 2023-08-30 2025-03-05 SPH Sine Pharmaceutical Laboratories Co., Ltd Antiviral nasal spray comprising favipiravir
CN117562911B (zh) * 2023-12-07 2024-06-04 海南医学院 化合物tigloside在制备治疗和/或预防骨关节炎药物中的用途
WO2025133675A1 (en) * 2023-12-20 2025-06-26 Melikoglu, Ahmet Method for producing nasal formulation comprising aescin and rutin
EP4696300A1 (en) 2024-08-14 2026-02-18 Marinomed Biotech AG Aqueous composition comprising fluticasone
KR102907892B1 (ko) * 2025-01-09 2026-01-12 주식회사 한바이오 가용성을 높인 피레스로이드계의 보건용 스프레이 살충제 제조방법

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IL256882B (en) 2021-12-01
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DK3324933T3 (da) 2021-01-18
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IL256882A (en) 2018-03-29
EP3324933A1 (en) 2018-05-30
MY196065A (en) 2023-03-13
CY1124322T1 (el) 2022-07-22
PH12018500042A1 (en) 2018-07-09
ES2844581T3 (es) 2021-07-22
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ZA201708594B (en) 2019-06-26
EA036233B1 (ru) 2020-10-16
CA2992376A1 (en) 2017-01-19
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EP3324933B1 (en) 2020-12-16
JP2019501861A (ja) 2019-01-24
CL2018000032A1 (es) 2018-11-16
WO2017009480A1 (en) 2017-01-19
EA201890194A1 (ru) 2018-10-31
CN107847440A (zh) 2018-03-27
CO2018001460A2 (es) 2018-05-10
SA518390688B1 (ar) 2022-03-13
SI3324933T1 (sl) 2021-04-30
MX2018000286A (es) 2018-02-19
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CA2992376C (en) 2023-06-20
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AU2016293125A1 (en) 2018-01-18
RS61561B1 (sr) 2021-04-29
CN107847440B (zh) 2021-06-25
KR20180054569A (ko) 2018-05-24
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