KR102063271B1 - Ultrasound treatment apparatus and driving method thereof - Google Patents

Abstract

One embodiment of the present invention, the respiratory sensor unit for generating a respiratory detection signal by detecting one respiratory cycle of the subject; An information processor extracting a synchronization signal corresponding to any one time period of the one breathing cycle by using the breathing detection signal; A magnetic resonance image generating unit including a hollow to which a magnetic field for capturing magnetic resonance images is applied and generating a magnetic resonance image of a region of interest of the object according to the synchronization signal; An ultrasound probe generating an ultrasound probe for radiating ultrasound to the ROI of the object, the ultrasound image generator being disposed on one side of the MRI generator to generate an ultrasound image of the ROI; And an ultrasonic treatment unit disposed at one side of the magnetic resonance image generating unit and configured to irradiate focused ultrasound to the region of interest using the ultrasonic image and the magnetic resonance image. .

Description

Ultrasound treatment apparatus and driving method thereof

Embodiments of the present invention relate to an ultrasound therapy apparatus and a driving method thereof, and more particularly, to an ultrasound therapy apparatus and a driving method thereof capable of accurately tracking a tumor.

High-Intensity focused ultrasound (HIFU) treatment is a non-invasive and non-traumatic approach. This applies especially to patients with tumors. Compared with conventional surgical treatment or chemotherapy, HIFU treatment gives less trauma to the patient and its application is increasing rapidly. These signs include liver cancer, bone sarcoma, breast cancer, pancreas cancer, kidney cancer, soft tissue tumors and pelvic tumors. It includes.

Most HIFU treatments use ultrasound imaging devices to position the subject tumor in the region of interest and monitor the treatment. The ultrasound imaging apparatus is a device for transmitting ultrasound toward an object to be diagnosed and forming and displaying an image of the object from the reflected ultrasound, and is expressed as a B-mode (brightness-mode) using a reflection coefficient of human tissue.

On the other hand, some HIFU treatments use magnetic resonance imaging (MRI) for this purpose, which visualizes the image by obtaining information from the degree of magnetic relaxation between tissues. MRI is a diagnostic technique that uses a magnetic field to create a picture of the structures inside the body. MRI generates images based on how hydrogen atoms in the human body react with magnetic fields and electromagnetic waves. Based on the above principles, MRI is used to detect soft tissue tumors in the body, such as the brain, spinal cord, heart, eye, liver, pancreas, kidney, breast and prostate, and to examine diseases. However, MRI is the only imaging method that can measure the temperature of the cautery range, but there is a problem of being vulnerable to virtual injury due to long-term exercise or intestinal air.

(Patent Document 1) KR10-2004-0058269A (2004.07.03)

In order to solve this problem, embodiments of the present invention to generate a magnetic resonance image by using a signal synchronized to the respiratory cycle, to provide an ultrasound therapy apparatus and a method of driving the accurate location tracking of tumors in the moving organs do.

One embodiment of the present invention, the respiratory sensor unit for generating a respiratory detection signal by detecting one respiratory cycle of the subject; An information processor extracting a synchronization signal corresponding to any one time period of the one breathing cycle by using the breathing detection signal; A magnetic resonance image generating unit including a hollow to which a magnetic field for capturing magnetic resonance images is applied and generating a magnetic resonance image of a region of interest of the object according to the synchronization signal; An ultrasound probe generating an ultrasound probe for radiating ultrasound to the ROI of the object, the ultrasound image generator being disposed on one side of the MRI generator to generate an ultrasound image of the ROI; And an ultrasonic treatment unit disposed at one side of the magnetic resonance image generating unit and configured to irradiate focused ultrasound to the region of interest using the ultrasonic image and the magnetic resonance image. .

In one embodiment of the present invention, the time period may be included in the exhalation period of the one breathing cycle.

In one embodiment of the present invention, the time period may include a first time point to stop breathing in the respiratory cycle.

In an embodiment of the present invention, the information processing unit extracts a second time point at which a value calculated by differentiating the respiration detection signal becomes a preset threshold value, and the time period is the first time point and the second time point. It may be a section between.

In one embodiment of the present invention, the input means for generating an input signal in response to the external periodic input may further include a.

In an embodiment of the present disclosure, when the third time point of the input signal is included in the time period, the information processing unit may correspond to the third time point.

In one embodiment of the present invention, the ultrasound image generating unit and the ultrasound treatment unit may be integrally formed.

In one embodiment of the present invention, the center of the ultrasound treatment unit may coincide with the center of the ultrasound probe.

In one embodiment of the present invention, a moving table which can be moved into the hollow of the magnetic resonance image generating unit; may further include.

In one embodiment of the present invention, the ultrasound image generator and the ultrasound treatment unit may be disposed on the moving table.

In one embodiment of the present invention, one side is connected to the moving table, it may further include a fixing means for fixing the ultrasound image generating unit and the ultrasound treatment unit disposed on the upper portion of the object.

In one embodiment of the present invention, the magnetic resonance image and the display unit for displaying the ultrasound image to the outside; may further include a.

One embodiment of the present invention, by detecting the respiratory cycle of the subject by the breathing sensor to generate a breathing detection signal; Extracting, by an information processing unit, a synchronization signal corresponding to any one time period of the one breathing cycle using the breathing detection signal; Generating a magnetic resonance image of the ROI of the object according to the synchronization signal by the magnetic resonance image generator; Generating an ultrasound image of the ROI by an ultrasound image generator which includes an ultrasound probe for irradiating ultrasound of the ROI to the ROI of the object and is disposed on one side of the MRI generator; And irradiating focused ultrasound to the region of interest using the ultrasound image and the magnetic resonance image by an ultrasound treatment unit disposed at one side of the magnetic resonance image generating unit. Step and generating the magnetic resonance image is performed at the same time, provides a driving method of the ultrasound therapy apparatus.

In one embodiment of the present invention, the time period may be included in the exhalation period of the one breathing cycle.

In one embodiment of the present invention, the time period may include a first time point to stop breathing in the respiratory cycle.

In an embodiment of the present disclosure, the extracting of the synchronization signal may include: extracting, by the information processor, a second time point at which a value calculated by differentiating the respiration detection signal becomes a preset threshold; Includes, the time period may be a section between the first time point and the second time point.

In an embodiment of the present disclosure, the method may further include generating, by the input means, a periodic input signal in response to an external periodic input.

In an embodiment of the present disclosure, the extracting of the synchronization signal may further include: corresponding to the third time point when the third time point at which the input signal is input is included in the time period. can do.

In an embodiment of the present disclosure, the display unit may further include displaying the ultrasound image and the magnetic resonance image to the outside.

An embodiment of the present invention provides a computer program stored in a medium for executing the method of any one of claims 13 to 19 using a computer.

Other aspects, features, and advantages other than those described above will become apparent from the following drawings, claims, and detailed description of the invention.

Ultrasonic therapy apparatus and a driving method thereof according to embodiments of the present invention by taking a magnetic resonance image in accordance with the synchronization signal corresponding to the time when the breathing stops through the breathing sensor unit and the information processing unit, the ultrasound image and the magnetic resonance image in real time It can be provided, through which the accurate location tracking and temperature measurement of the region of interest is possible to enable a stable ultrasound treatment.

1 is a perspective view schematically showing an ultrasound therapy apparatus according to an embodiment of the present invention.
FIG. 2 is a cross-sectional view taken along the line II-II 'of FIG. 1.
3 is a block diagram of the ultrasound therapy apparatus of FIG. 1.
4 is a cross-sectional view schematically showing an ultrasound image generator and an ultrasound therapy unit of the ultrasound therapy apparatus according to an embodiment of the present invention.
Figure 5 (a) is a graph showing one breathing cycle of the breathing sensor unit shown in Figure 1, Figure 5 (b) is a time point when the magnetic resonance image is generated by the magnetic resonance image generating unit shown in FIG. It is a schematic graph.
6 is a diagram illustrating an example of an ultrasound image and a magnetic resonance image.
7 is a cross-sectional view schematically showing an ultrasound therapy apparatus according to another embodiment of the present invention.
8 is a flowchart schematically showing a method of driving an ultrasound therapy apparatus according to an embodiment of the present invention.

As the invention allows for various changes and numerous embodiments, particular embodiments will be illustrated in the drawings and described in detail in the written description. Effects and features of the present invention, and methods of achieving them will be apparent with reference to the embodiments described below in detail together with the drawings. However, the present invention is not limited to the embodiments disclosed below but may be implemented in various forms.

Hereinafter, exemplary embodiments of the present invention will be described in detail with reference to the accompanying drawings, and the same or corresponding components will be denoted by the same reference numerals, and redundant description thereof will be omitted. .

In the following embodiments, the terms first, second, etc. are used for the purpose of distinguishing one component from other components rather than a restrictive meaning.

In the following examples, the singular forms "a", "an" and "the" include plural forms unless the context clearly indicates otherwise.

In the following examples, the terms including or having have meant that there is a feature or component described in the specification and does not preclude the possibility of adding one or more other features or components.

In the following embodiments, when a part such as a film, a region, a component, or the like is on or on another part, not only is it directly above the other part, but also another film, a region, a component, etc. is interposed therebetween. It also includes cases where there is.

In the drawings, components may be exaggerated or reduced in size for convenience of description. For example, the size and thickness of each component shown in the drawings are arbitrarily shown for convenience of description, and thus the present invention is not necessarily limited to the illustrated.

In the case where an embodiment may be implemented differently, a specific process order may be performed differently from the described order. For example, two processes described in succession may be performed substantially simultaneously or in the reverse order of the described order.

In the following embodiments, when a film, a region, a component, or the like is connected, not only the film, the region, and the components are directly connected, but also other films, regions, and components are interposed between the film, the region, and the components. And indirectly connected. For example, in the present specification, when the film, the region, the component, and the like are electrically connected, not only the film, the region, the component, and the like are directly electrically connected, but other films, the region, the component, etc. are interposed therebetween. This includes indirect electrical connections.

1 is a perspective view schematically showing an ultrasound therapy apparatus 10 according to an embodiment of the present invention, Figure 2 is a cross-sectional view taken along the line II-II 'of FIG. 3 is a block diagram of the ultrasound therapy apparatus 10 of FIG. 1.

1 to 3, the ultrasound therapy apparatus 10 according to an embodiment of the present invention includes a magnetic resonance image generator 110, an ultrasound image generator 131, an ultrasound therapy unit 135, and a breathing sensor. The unit 120 and the information processing unit 150 is included. In addition, the ultrasound treatment apparatus 10 may further include a moving table 180, an input unit 190, and a display unit 160. Here, the display 160 may display the magnetic resonance image and the ultrasound image to the outside.

The magnetic resonance image generating unit 110 may include a hollow A to which a magnetic field for magnetic resonance imaging (MRI) is applied. The hollow A may have a cylindrical shape with an empty internal space. The magnetic resonance image generating unit 110 includes a gantry (gantry) surrounding the hollow (A), the static magnetic field coil 115 and the gradient coil (arranged to surround the hollow (A) inside the gantry (gantry)) 113). The static field coil 115 forms a static field in the hollow A, and the gradient coil 113 applies a gradient to the static field to generate a gradient filed. In addition, although not shown, the magnetic resonance image generating unit 110 may further include an RF coil (not shown) for applying an RF pulse to the object to excite the atomic nucleus and receive an echo signal from the atomic nucleus.

4 is a cross-sectional view schematically showing the ultrasound image generating unit 131 and the ultrasound treatment unit 135 of the ultrasound treatment apparatus 10 according to an embodiment of the present invention.

Referring to FIG. 4, the ultrasound image generator 131 includes an ultrasound probe that irradiates an ultrasound image for imaging to a region of interest g of the object P, and is adjacent to the magnetic resonance image generator 110. Can be arranged. Here, the object P may be a living body of a human or an animal, or an in vivo tissue such as blood vessels, bones, muscles, etc., but is not limited thereto, and the internal structure may be imaged by the ultrasound image generating unit 131. It may be the object (P). The ultrasound probe may include at least one transducer, and may transmit an ultrasound signal to the object P, and receive echo ultrasound reflected from the object P using the at least one transducer. The ultrasound image generator 131 may generate an ultrasound image by using echo ultrasound.

The ultrasound treatment unit 135 may be disposed on one side of the magnetic resonance image generating unit 110 and irradiate focused ultrasound to the region of interest g using the ultrasound image and the magnetic resonance image. The ultrasound treatment unit 135 may include a hollow frame and a plurality of ultrasonic elements disposed on the inner surface of the hollow frame. The hollow frame has a concave hemispherical or flat shape, a plurality of ultrasonic elements are located on the inner surface of the hemispherical or flat hollow frame, the ultrasonic element can irradiate focused ultrasound to the region of interest (g). By plural ultrasonic elements positioned on the inner surface of the hemispherical hollow frame, the therapeutic ultrasonic waves can be concentrated on the region of interest g.

The ultrasound image generator 131 and the ultrasound treatment unit 135 may be integrally formed as shown in FIG. 4. In this case, the integrated ultrasound image generator 131 and the ultrasound treatment unit 135 will be defined as the ultrasound unit 130. In an embodiment, the center of the ultrasound treatment unit 135 may coincide with the center of the ultrasound probe 131. However, the present invention is not limited thereto, and as another embodiment, the center of the ultrasound treatment unit 135 may be different from the center of the ultrasound probe 131.

Meanwhile, the ultrasound treatment apparatus 10 may arrange the magnetic resonance image generating unit 110 and the ultrasonic unit 130 adjacent to each other, and simultaneously perform the ultrasound treatment together with the imaging of the ultrasound image and the magnetic resonance image. In this case, the ultrasound unit 130, in particular the ultrasound treatment unit 135 may be made of a material (MR compatible) compatible with the magnetic resonance image generating unit 110. Specifically, the ultrasound unit 130 may be made of a nonmagnetic material. For example, the ultrasound unit 130 may be made of a material such as reinforced plastic or austenitic cast iron, except for parts that should be electrical or magnetic materials such as connection wirings of ultrasonic elements or driving circuits. In addition, the ultrasound treatment unit 135 may be compatible with the magnetic resonance image generating unit 110 by using a hydraulic motor instead of an electric motor. However, the present invention is not limited thereto, and may be applied to the ultrasound unit 130 as long as the material or configuration is compatible with the magnetic resonance image generating unit 110.

1 to 4, the ultrasound therapy apparatus 10 may further include a moving table 180 that may move into the hollow A of the magnetic resonance image generator 110. The ultrasound unit 130 including the unit 131 and the ultrasound treatment unit 135 may be disposed on the moving table 180. As an example, the ultrasound unit 130 may be disposed inside the movement table 180 to face the top surface of the movement table 180. In this case, the ultrasound treatment unit 135 and the ultrasound image generator 131 may irradiate ultrasound toward the region of interest g of the object P positioned on the upper surface of the movement table 180. In addition, the moving table 180 may include a treatment table 181 on which the object P is placed, and a guide table 183 for guiding the treatment table 181 to enter or exit into the hollow A. FIG. In this case, the ultrasound treatment unit 135 and the ultrasound image generator 131 may be disposed on the treatment table 181.

Although not illustrated, the ultrasound unit 130 may further include a receiving unit (not shown) surrounding the ultrasound treatment unit 135. The accommodating part (not shown) may accommodate the coupling liquid for preventing the internal reflection of the ultrasonic part 130 by the reflection coefficient difference. The coupling liquid may include a material capable of achieving acoustic coupling, and in one embodiment, may be water. However, the present invention is not limited thereto, and as another embodiment, the coupling liquid may be oil (fat).

The breathing sensor unit 120 may generate a breathing detection signal by detecting one breathing cycle of the object P. The breathing sensor unit 120 may be attached to one region of the object P to detect one breathing cycle.

The information processor 150 may extract a synchronization signal corresponding to any one time period of one breathing cycle by using the breathing detection signal generated from the breathing sensor 120. The magnetic resonance image generator 110 may generate a magnetic resonance image of the region of interest g according to the extracted synchronization signal.

5 (a) is a graph showing one respiratory cycle of the respiratory sensor unit 120 shown in FIG. 1, Figure 5 (b) is a magnetic resonance image generating unit 110 shown in FIG. It is a graph schematically showing the time point when the resonance image (M) is generated. 6 is a view showing an example of the ultrasound image (U) and the magnetic resonance image (M).

Referring to Figures 5 (a) and (b), the graph shows the respiratory volume over time. The section in which the respiratory rate increases is an inspiration section A, and the section in which the respiratory volume decreases becomes an exhalation section B. The magnetic resonance image generating unit 110 may photograph when the region of interest g does not move. In other words, the magnetic resonance image generating unit 110 may take a magnetic resonance image (M) when the breathing stops.

When the breathing stops using the breathing detection signal provided from the breathing sensor unit 120, that is, the information processing unit 150 generates a synchronization signal corresponding to any one time period of the one breathing cycle, the magnetic resonance image It may be provided to the generation unit 110. The time period may be included in the expiration period (B) of one breathing cycle. Exhalation section (B) is longer than the inhalation section (A) is a breathing stop longer, the magnetic resonance image generation unit 110 can stably photograph the magnetic resonance image (M) in the exhalation section (B). However, the present invention is not limited to this.

The time period may include a first time point at which breathing stops during the breathing cycle. Referring to FIG. 5, a time point at which breathing stops during one respiration cycle is a first-first time point Ta in the inspiration period A and a first-second time point Tb in the exhalation period B. However, when the time period is included in the expiration period (B), the first time point may correspond to the 1-2 time point (Tb).

On the other hand, the information processor 150 may extract a second time point Tr at which a value calculated by differentiating the respiration detection signal becomes a preset threshold. In detail, the information processor 150 may calculate a slope for each time point by differentiating a respiration detection signal representing a respiration volume over time. In this case, when the slope is 0, it may be determined as the time when the breathing stops. However, since it may not be possible to completely differentiate the retardation of the respiratory detection signal in a periodic respiration cycle, a threshold value close to zero may be set in advance and stored in the information processing unit 150. The information processing unit 150 may extract a second time point Tr when the value calculated by differentiating the respiration detection signal becomes the threshold value, and then define a section between the first time point and the second time point as a time period. . Accordingly, the magnetic resonance image generating unit 110 may generate and generate the magnetic resonance image M between the first time point Tb and the second time point Tr during one breathing cycle. In this case, the ultrasound image generator 131 may continuously generate an ultrasound image of the region of interest g, and the magnetic resonance image M may intermittently generate the magnetic resonance image M of the region of interest g. . However, since the generation process is performed at the same time, the ultrasound therapy apparatus 10 according to an embodiment of the present invention may provide an ultrasound image U and a magnetic resonance image M in real time, and through the region of interest ( g) accurate position tracking and temperature measurement are possible, so that stable ultrasound treatment is possible.

As another embodiment, the ultrasound therapy apparatus 10 may further include an input unit 190 (refer to FIG. 3) for generating an input signal in response to an external periodic input. The input means 190 may include a button that the object P can press at the time when the breathing stops. The information processor 150 according to an embodiment determines a time period including a time point at which breathing stops using the breathing detection signal generated from the breathing sensor unit 120. However, in order to minimize the measurement error of the respiratory sensor unit 120, the ultrasound treatment apparatus 10 of another embodiment may further include an input means 190 to extract the exact respiratory stop time input from the object (P). have.

In this case, the ultrasound treatment apparatus 10 may further include a guide means (not shown) for recognizing and inputting an accurate respiration stop time through the respiration education of the object (P). For example, the guide means may be a lighting that can be visually recognized by the object P or a speaker that can be audibly recognized. The object (P) is able to press the button at the point where the breathing stops exactly through the breathing training using the guide means. The information processor 150 may determine whether the third time point at which the input signal is generated is included in the time period, and, when included, may correspond to the third time point. In other words, the information processor 150 may generate a synchronization signal to capture the magnetic resonance image M at the third time point at which the breathing stops.

7 is a schematic cross-sectional view of an ultrasound therapy apparatus 20 according to another exemplary embodiment, and FIG. 8 is a schematic cross-sectional view of an ultrasound therapy apparatus 30 according to another embodiment. Other embodiments of the present invention and the other embodiments are the same as the ultrasound treatment apparatus according to an embodiment except for the arrangement position of the ultrasound unit, duplicate description will be omitted.

Referring to FIG. 7, the ultrasound treatment apparatus 20 according to another embodiment may further include fixing means 237 for fixing the ultrasound image generator (not shown) and the ultrasound treatment unit 235. The fixing means 237 may be fixed so that one side is connected to the moving table 180 and the ultrasound image generator and the ultrasound treatment unit 235 are disposed on the object P. In this case, the region of interest g may be a tumor of an organ located in the abdomen, such as the liver and the kidney.

8 is a flow chart schematically showing a method of driving the ultrasound therapy apparatus 10 according to an embodiment of the present invention.

Referring to FIG. 8, the ultrasound image generator 131 includes an ultrasound probe for irradiating an ultrasound image for imaging to a region of interest g of the object P, and continuously performs an ultrasound image of the region of interest g during treatment. To generate (S1).

On the other hand, the breathing sensor 120 detects one breathing cycle of the object (P) generates a breathing detection signal (S2). Thereafter, the information processing unit 150 extracts a synchronization signal corresponding to any one time period of one breathing cycle using the breathing detection signal (S3), and the magnetic resonance image generating unit 110 generates a region of interest according to the synchronization signal ( Generate a magnetic resonance image of g) (S4).

In detail, the information processor 150 may extract a first time point at which breathing stops and a second time point at which a value calculated by differentiating the respiration detection signal becomes a preset threshold value among the respiration detection signals. The time section is a section between the first time point and the second time point. The information processing unit 150 provides a synchronization signal corresponding to the time period to the magnetic resonance image generation unit 110, and the magnetic resonance image generation unit 110 intermittently generates the magnetic resonance image at a time corresponding to the time period during the respiration cycle. Shoot and create. Here, since a detailed method of generating the synchronization signal by the information processing unit 150 has been described above, overlapping description will be omitted.

Generating the magnetic resonance image (S4) is performed simultaneously with generating the ultrasound image (S1), the continuous ultrasound image and the intermittent magnetic resonance image is provided to the ultrasound treatment unit 135. Thereafter, the ultrasound treatment unit 135 irradiates the focused ultrasound to the region of interest g using the magnetic resonance image and the ultrasound image (S5).

As described above, the ultrasound treatment apparatus and its driving method according to the embodiments of the present invention by taking a magnetic resonance image (M) in accordance with the synchronization signal corresponding to the point of stopping the breathing through the breathing sensor unit and the information processing unit, Ultrasonic image (U) and magnetic resonance image (M) can be provided in real time, and through this, accurate position tracking and temperature measurement of the region of interest (g) is possible and thus stable ultrasound treatment is possible.

Embodiments according to the present invention described above may be implemented in the form of a computer program that can be executed through various components on a computer, such a computer program may be recorded on a computer readable medium. At this time, the media may be magnetic media such as hard disks, floppy disks and magnetic tape, optical recording media such as CD-ROMs and DVDs, magneto-optical media such as floptical disks, and ROMs. Hardware devices specifically configured to store and execute program instructions, such as memory, RAM, flash memory, and the like. Furthermore, the medium may be implemented, for example, in the form of software or an application.

On the other hand, the computer program is specifically designed and configured for the present invention, but may be known and available to those skilled in the computer software field. Examples of computer programs may include not only machine code generated by a compiler, but also high-level language code executable by a computer using an interpreter or the like.

Particular implementations described in the present invention are examples and do not limit the scope of the present invention in any way. For brevity of description, descriptions of conventional electronic configurations, control systems, software, and other functional aspects of the systems may be omitted. In addition, the connection or connection members of the lines between the components shown in the drawings are illustrative of the functional connection and / or physical or circuit connections as an example, in the actual device replaceable or additional various functional connections, physical It may be represented as a connection, or circuit connections. In addition, unless specifically mentioned, such as "essential", "important" may not be a necessary component for the application of the present invention.

Therefore, the spirit of the present invention should not be limited to the above-described embodiments, and the scope of the spirit of the present invention is defined not only in the claims below, but also in the ranges equivalent to or equivalent to those of the claims. Will belong to.

10: ultrasound therapy device
110: magnetic resonance image generating unit
120: breathing sensor
131: ultrasonic image generating unit
135: ultrasonic treatment unit
150: information processing unit
160: display unit
180: moving table
190: input means

Claims (20)

A breathing sensor unit configured to detect one breathing cycle of the object and generate a breathing detection signal;
An information processor extracting a synchronization signal corresponding to any one time period of the one breathing cycle by using the breathing detection signal;
A magnetic resonance image generating unit including a hollow to which a magnetic field for capturing magnetic resonance images is applied and generating a magnetic resonance image of a region of interest of the object according to the synchronization signal;
An ultrasound probe generating an ultrasound probe for radiating ultrasound to the ROI of the object, the ultrasound image generator being disposed on one side of the MRI generator to generate an ultrasound image of the ROI; And
And an ultrasonic treatment unit disposed at one side of the magnetic resonance image generating unit and irradiating focused ultrasound to the region of interest using the ultrasonic image and the magnetic resonance image. The method of claim 1,
The time period is included in the exhalation period of the one respiratory cycle, ultrasound treatment apparatus. The method of claim 1,
The time period includes an ultrasonic treatment device, the first time the breathing stops during the breathing cycle. The method of claim 3,
The information processor extracts a second time point at which a value calculated by differentiating the respiration detection signal becomes a preset threshold value,
The time interval is an interval between the first time point and the second time, the ultrasound treatment apparatus. The method of claim 4, wherein
And an input means for generating an input signal in response to an external periodic input. The method of claim 5,
And the information processing unit corresponds to the third time point when the third time point of the input signal is included in the time period. The method of claim 1,
The ultrasound image generating unit and the ultrasound treatment unit is integrally formed, the ultrasound treatment apparatus. The method of claim 1,
The center of the ultrasonic treatment unit (center) coincides with the center of the ultrasonic probe, the ultrasonic treatment apparatus. The method of claim 1,
And a moving table capable of moving into the hollow of the magnetic resonance image generating unit. The method of claim 9,
The ultrasound image generating unit and the ultrasound treatment unit is disposed on the moving table, ultrasound treatment apparatus. The method of claim 9,
One side is connected to the moving table, and further comprising a fixing means for fixing the ultrasound image generating unit and the ultrasound treatment unit disposed on the upper portion of the object. The method of claim 1,
And a display unit configured to display the magnetic resonance image and the ultrasound image to the outside. Generating, by the breathing sensor unit, a breathing detection signal by sensing one breathing cycle of the object;
Extracting, by an information processing unit, a synchronization signal corresponding to any one time period of the one breathing cycle using the breathing detection signal;
Generating a magnetic resonance image of the ROI of the object according to the synchronization signal by the magnetic resonance image generator;
Generating an ultrasound image of the ROI by an ultrasound image generator which includes an ultrasound probe for irradiating the ultrasound of imaging to the ROI of the object and is disposed on one side of the MRI generator; And
Irradiating focused ultrasound to the region of interest using the ultrasound image and the magnetic resonance image by an ultrasonic treatment unit disposed at one side of the magnetic resonance image generating unit;
The generating of the ultrasound image and the generating of the magnetic resonance image are simultaneously performed. The method of claim 13,
The time period is included in the exhalation period of the one breathing cycle, the driving method of the ultrasonic treatment device. The method of claim 13,
The time period includes a first point of time when the breathing stops in the breathing cycle, the driving method of the ultrasonic treatment device. The method of claim 15,
Extracting the synchronization signal,
And extracting, by the information processor, a second time point at which a value calculated by differentiating the respiration detection signal becomes a preset threshold value.
The time period is a section between the first time and the second time, the driving method of the ultrasound treatment apparatus. The method of claim 16,
And generating, by the input means, a periodic input signal in response to an external periodic input. The method of claim 17,
Extracting the synchronization signal,
And when the third time point at which the input signal is input is included within the time period, corresponding the synchronization signal to the third time point. The method of claim 13,
And displaying, by a display unit, the ultrasound image and the magnetic resonance image to the outside. A computer program stored in a recording medium for executing the method of any one of claims 13 to 19 using a computer.

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