KR101974752B1 - Cream for treatment of pressure sore and method for manufacturing the same - Google Patents

Cream for treatment of pressure sore and method for manufacturing the same Download PDF

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Publication number
KR101974752B1
KR101974752B1 KR1020170185058A KR20170185058A KR101974752B1 KR 101974752 B1 KR101974752 B1 KR 101974752B1 KR 1020170185058 A KR1020170185058 A KR 1020170185058A KR 20170185058 A KR20170185058 A KR 20170185058A KR 101974752 B1 KR101974752 B1 KR 101974752B1
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natural
cream
ingredients
vegetable oil
hyaluronic acid
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KR1020170185058A
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Korean (ko)
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황혜미
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황혜미
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/708Rheum (rhubarb)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Abstract

The present invention discloses a cream for treating bedsores and a method of making the same. Cream for the treatment of bedsores of the present invention, natural ingredients and essential oils and moisturizers extracted from Hyunsam, white paper, Angelica, broiler, red peony, rhubarb and raw sulfur, but the natural material is 50% by weight, the essential oil is 5% % And the moisturizer is 45% by weight.

Description

CREAM FOR TREATMENT OF PRESSURE SORE AND METHOD FOR MANUFACTURING THE SAME}

The present invention relates to creams for the treatment of bedsores and a method for producing the same, and more particularly, to a bedsore treatment cream for treating bedsores with an active ingredient derived from natural materials and a method for producing the same.

In general, when a constant or repeated pressure is applied to a specific part of the human body, the ulcers caused by tissue death due to poor blood circulation mainly due to the protrusion on the bones are called bedsores. The common cause of these symptoms is compression, which is more appropriately called compression ulcers.

Such pressure sores are common in patients lying for long periods of time. Bed sores itself may not be a major problem, but the most serious complication of bed sores is pulmonary pneumonia, which spreads to the bed sores and spreads throughout the system, and mortality rates of 60% occur when bedsores cause pneumonia. It is becoming.

Thus, various attempts have been made to treat bedsores early to prevent progression to pulmonary disease.

Prior art document 1 relates to a composition for treating bedsores and burns. The composition for treating bedsores and burns of prior art document 1 is characterized by containing silicon dioxide, aluminum oxide, iron oxide, titanium dioxide, calcium oxide, magnesium oxide, sodium oxide, potassium oxide and the like. This prior art document 1 provides a bedside treatment agent with few side effects, but because it contains a major chemical component, such a therapeutic agent can cause side effects in patients sensitive to these chemical components.

Prior art document 2 is a technique related to the composition for wound coating made of a natural extract. Prior art document 2 relates to a composition for wound coating having a low skin irritation, and can be applied to minor burns, bedsores and lower extremities. However, it has been pointed out that the effect is insignificant in the case of a slight pressure sore.

Prior Art Document 1: Korean Patent No. 10-1530574 (June 22, 2015 announcement) Prior Art Document 2: Korean Patent Registration No. 10-1809182 (announced Dec 08, 2017)

The present invention devised to solve the above problems is an object of the present invention to provide a bedsore treatment cream excellent in treating pressure sores with less skin irritation using a composition derived from natural materials.

Cream for treating bedsores according to an embodiment of the present invention in order to achieve the above object includes natural ingredients and essential oils and moisturizers extracted from Hyunsam, white paper, Angelica, broiler, red peony, rhubarb and raw jihwang, the natural material is 50% by weight, the essential oil is 5% by weight and the moisturizer is 45% by weight.

In this case, the natural material is impregnated with vegetable oil in the same proportion of Hyunsam, white paper, Angelica, broiler, red peony, rhubarb and raw sulfur in the same ratio for a predetermined time, and then heating the resultant to remove the vegetable oil to a predetermined temperature Extracted result.

Meanwhile, the essential oil is composed of Frankincence, Lavender, Tea Tree, or a combination thereof.

On the other hand, the moisturizing agent is composed of hyaluronic acid (hyaluronic acid) and EGF (epidermal growth factor).

Method for producing a bedsore treatment cream according to another embodiment of the present invention, the step of roasting natural ingredients consisting of Hyunsam, white paper, Angelica, broiler, red peony, rhubarb and raw jihwang in a pan (S101), roasted natural ingredients vegetable oil Impregnating (S102), removing the vegetable oil from the natural material (S103), bridging the natural material (S104) to remove a specific ingredient from the natural material, Frankin sense (depending on the result) Adding an essential oil consisting of Frankincence, Lavender, tea tree, or a combination thereof (S105); And adding hyaluronic acid and EGF (epidermal growth factor) after adding the essential oil (S106).

According to various embodiments of the present invention, using a composition derived from a natural material exhibits an excellent effect in treating pressure sores with less skin irritation.

1 is a flow chart illustrating a method of manufacturing a pressure sore treatment cream according to an embodiment of the present invention;
Figure 2a, 2b is a view comparing before and after applying the bedsore treatment cream according to an embodiment of the present invention.

Other objects, features and advantages of the present invention will become apparent from the following detailed description of embodiments with reference to the accompanying drawings.

Referring to a preferred embodiment of the bedsore treatment cream according to the present invention. However, the present invention is not limited to the embodiments disclosed below, but may be implemented in various forms, and only the present embodiments are intended to complete the disclosure of the present invention and to those skilled in the art to fully understand the scope of the invention. It is provided to inform you. Therefore, the exemplary embodiments described herein are only exemplary embodiments of the present invention, and do not represent all of the technical ideas of the present invention, and various equivalents and modifications that may substitute them at the time of the present application may be included. It should be understood that there may be.

The main components of the bedsore treatment cream of the present invention include components derived from natural materials, essential oils and moisturizing components. Hereinafter, a natural material component is demonstrated.

1. Ingredients of natural ingredients

Cream for treating bedsores according to an embodiment of the present invention includes a natural material. Natural ingredients include brown ginseng, white paper, donkeys, broilers, red peony, rhubarb and raw turmeric.

Hyunsam is a perennial plant of the family Hyunsam. The scientific name is Scrophularia buergeriana. Hyunsam is a major, modern, and ear jewel. Also called a horse. Hyunsam grows in mountainous area and its roots are thick and 80 ~ 150cm high. The cross section of Hyunsam is rectangular and has no branches. The leaves of Hyunsam are opposite each other, long ovate, pointed at the end, sawtooth at the edge, and petiole is short. Hyunsam is an antipyretic and is used for sore throat, boil and lymphitis.

White paper is a medicinal herb made from dried roots of the Angelica dahurica Bentham et Hooker or its variants. White paper is a pharmacological action, antibacterial action, animal soft vascular movement center, respiratory center, excitatory function of the vagus nerve and spinal cord, coronary blood flow increase effect, baekjeon wind (白 殿 風)病: Chronic skin disease, an effect of multiple layers of white scales on the surface of the skin due to erythema and papules.

Angelica refers to the dried roots of Angelica gigas Nakai in Korea and Angelica sinensis (Oliv.) Diels in China. In Japan, the roots of the morphotype and Angelica acutiloba (Siebold. & Zucc.) Kitag.

Angelica is the main blood production (補血 作用) to produce blood when the lack of blood. Donkeys made from the roots of Chinese donkeys and Koreans donkeys have an excellent blood donating effect, but donkeys made from the roots of true donkeys have better blood circulation than the blood donating action. It is known to be strong. Angelica pharmacologically promotes blood flow in the coronary arteries and stimulates red blood cell production.

Broilers are the bark of the cassia (Cinnamomum cassia Presl) intact or slightly removed from the bark. Broilers may be of different origin and quality in different regions. In particular, Vietnamese produce broilers up to 5 grades. Also, since broiler chickens have different harvesting ages and processing methods, commodity standards are relatively different in terms of length, relation, plate, heart, and chain. many.

Broilers suppress the central nervous system, so it has calming, analgesic and antipyretic effects. Cinnamon oil has a scent of dry stomach, which stimulates the release of saliva and gastric fluid by gently stimulating the stomach, helping digestion and suppressing ulcers. It is known to promote blood flow in the heart and coronary arteries, to increase anti-radioactivity and leukocyte count, and to inhibit skin fungi.

A peony is the root of a peony (Paeonia lactiflora Pallas) or other related plant (peony and Paeoniaceae). Along with donkey, Sukji Hwang belongs to the blood donation and treatment of dysmenorrhea, dysmenorrhea, dizziness, headache, etc. In addition, it is known to be effective in symptoms such as chest pain, digestive disorders caused by hepatic non-fluoride (화 不 和).

Rhubarb is a herb made from perennial rhubarb roots with Rhizome. Rhubarb is known to cause diarrhea, which is said to cause diarrhea, eliminating poison and heat in the body. Rhubarb cleans the intestines, promotes metabolism, and treats recessive constipation and bloated genus. It is also effective for headache, congestion, sore throat, constipation, nosebleeds, bleeding, and boils. It is also used for diuresis and edema. Its pharmacological action is known to promote colon movement, fever, lowering body temperature, promoting bile secretion, reducing blood clotting time, antibacterial, diuretic, and liver function.

Raw grasses are the family of the live grapes, Rehmannia glutinosa Libosch. var. purpurea is the root of Makino. Rehmanniapan (心 經), nerves (腎 經), cirrhosis (肝 經), small intestine (小腸 經) acts. Diurnal heat lowers the blood fever (血 熱), removes the essence and removes the blood. It is known in the pharmacological experiments that blood clot promoting action, cardiac action, diuretic action, hypoglycemic action, blood pressure raising action and the like. It is fever, chest tight, and thirsty, blood fever (血 熱) due to bleeding, ban (發 斑), bruises are effective.

2. Essential  Ingredients of oil

Franklinsense (Boswellia carteri) is an oil widely used since ancient Greece, Egypt and Roman times. The Egyptians are known to help relieve stress enough to believe that young people bathe in Frankins.

Frankin Sense is dried by hardening milky mucus extracted from frankincense tree trunks and obtained by steam distillation. Frankinces is characterized by a mild scent that seems to mix lemon and honey. Frankin Sense relieves symptoms such as asthma, bronchitis, cough, helps with cystitis, genital infections, nephritis, regenerates aging skin, relieves wrinkles and dry skin, and balances oily skin with astringent action It helps to hold and is known to be useful for wounds and inflamed areas.

Lavender (Lavendula angustifolia) is a plant native to the Mediterranean. Lavender is 30 ~ 60cm high and grows up to 90cm if it grows well in the garden. White hairs all over, stems are dull squares, clustered, and many branches are divided at the bottom. Leaves are rounded or opposite, lanceolate, 4cm long, 4-6mm wide. Petioles are absent and leaves have fine hairs.

It is cultivated for harvesting scented oil from lavender flowers and plants, and it is also planted for ornamental purposes. Lavender balm is used as an ingredient in perfumes and cosmetics, as a fragrance in cooking, and also used to treat headaches and nerves. Lavandula officnalis or Lavandula angustifolia species are mainly used for aromatherapy.

Lavender is also the most widely used oil in aromatherapy and can be applied directly to the skin. Relax and release the feelings of anger to calm you down. It is known to be effective for recovering from fatigue, calming, feelings of heart, dryness, gusts, disinfection and killing, and is effective for antiviral and antidepressant.

The tea tree (Melaleuca alternifolia) is native to Australia and grows in New South Wales and grows to about 6m in height. The tea tree grows in swamps and is known to grow well even when cutting stems. Tea tree is a kind of herb that refreshes air.

Tea tree is also effective in activating the immune system to fight infectious diseases. It activates leukocytes, has antibacterial and antifungal effects, and is also known to be effective against influenza, herpes, catarrh and gingivitis.

3. Ingredients of Moisturizer

Hyaluronic acid is one of complex polysaccharides composed of amino acids and uronic acids, and is a high molecular compound composed of N-acetylglucosamine and glucuronic acid. Hyaluronic acid is present in the vitreous body of the eye and the umbilical cord, etc., and is known to play a role in preventing the invasion of bacteria and infiltration of poisons.

Hyaluronic acid is known as a major mucopolysaccharide together with chondroitin sulfate and the like. N-acetylglucosamine and glucuronic acid are high molecular weight compounds of which the molecular weight is 200,000 to 400,000, which are alternately linked in a chain form. Hyaluronic acid is viscous and important for preventing the invasion of bacteria and invasion of poisons. It is similar to plant pectin and is hydrolyzed by hyaluronidase.

EGF (epidermal growth factor) is an epidermal growth factor. EGF is one of the peptides that promotes the proliferation of epithelial cells, and is used for skin transplantation and wound healing.

4. Composition of Cream for Bed Sore Treatment

main ingredient ratio main function Natural materials 50 wt% Relieve inflammation, increase blood flow, increase blood flow, skin fungal action, Essential oils 5 wt% Inflammation relief, antiseptic, antifungal effect Moisturizer 45 wt% Prevent bacteria invasion, promote upper body recovery

Referring to Table 1 above, the bedsore treatment cream includes natural ingredients, essential oils and moisturizers. That is, 50% by weight of natural materials, 5% by weight of essential oils and 45% by weight of the moisturizer.

Natural ingredients are impregnated with ginseng, white paper, donkey, broiler, red peony, rhubarb and raw sulfur in the same proportions for a predetermined time. For example, 40 g of wild ginseng, white paper, donkey, broiler, red peony, rhubarb and raw turmeric are roasted in a fry pan of Dalgun for at least 15 minutes and then impregnated with 1.2 kg of vegetable oil for 3 days (72 hours). Remove the vegetable oil from the ingredients impregnated with the vegetable oil and steam it in a low heat. The steaming process can be ironed out using a weak bath. Temperature setting can be set to high temperature, medium temperature, low temperature, the high temperature is heated to about 100 ℃, the medium temperature is heated to about 90 ℃, low temperature is heated to 80 ~ 85 ℃. The heating time can be variously changed to 24 hours, 48 hours, 72 hours and the like. The result of the bridge is used as a natural material.

Add essential oils to the natural ingredients. Essential oils consist of Frankincence, Lavender, tea tree, or a combination thereof.

Add the moisturizer component to the oiled result. The moisturizer component consists of hyaluronic acid and epidermal growth factor (EGF).

5. Manufacturing method of cream for bedsores

1 is a flow chart illustrating a method of manufacturing a cream for bedsore treatment according to an embodiment of the present invention. Referring to Figure 1, the step of roasting the natural ingredients in a heated pan (S101), the step of impregnating the roasted natural ingredients in vegetable oil (S102), removing the vegetable oil from the natural material (S103), removing a specific component Bridging the natural material (S104), adding essential oils to the run result (S105), and adding a moisturizer after adding the essential oils (S106).

In the step of roasting the natural material (S101), the strong ingredient of the natural material is removed by heating, and only the effective ingredient is left. For example, when heated, Hyunsam is an effective ingredient for bacteriostatic action, White is an ingredient that is effective for eliminating Changyang poisoning, Angelica is an ingredient that is effective for removing blood from blood, Broiler is an antiseptic ingredient, Red peony is an ingredient for pain relief and sterilization effect, Silver is an effective ingredient for antimicrobial efficacy, raw turmeric leaves active ingredients to relieve inflammation.

In the step of impregnating the roasted natural ingredients in vegetable oil (S102), when the natural ingredients are immersed in oil and immersed for a certain time (preferably 72 hours or more), the strong ingredients are reduced and the weakness is doubled.

In the step of removing the vegetable oil (S103), the process of filtering the vegetable oil from the resulting mixture of natural materials and vegetable oil using a strainer. Removing vegetable oils and adding essential oils will make the essential oils more effective.

In step (S104) of removing the specific ingredients, the specific temperature (low temperature (80-85 ° C), medium temperature (88 ° C-92 ° C), high temperature (92 ° C or higher), specific time (24 hours, 48 hours) It is a process of enriching the ingredients of each ingredient by squeezing natural ingredients at 72 hours (double hours). The ripening process is a process of bridging at low and medium temperatures for about 24 hours. It is the process of bridging at low and medium temperatures for hours.

In step (S105) of adding the essential oil to the resultant, inflammation relief, sterilization And essential oils for exerting an antifungal effect.

In the step (S106) of adding the moisturizer after adding the essential oil, the moisturizer is added to increase the moisturizing effect and to exert an effect of preventing skin soothing and drying.

Figure 2a, 2b is a view comparing before and after applying the bedsore treatment cream according to an embodiment of the present invention. As shown in FIG. 2A, it may be seen that pressure sores (dark areas) are distributed in the hip area of the patient. According to the result of observing the affected part of the cup after applying the cream for treating bedsores according to an embodiment of the present invention to the affected area three times a month, as shown in FIG. 2B, the bed sore is completely cured on the skin of the patient. You can check it.

Although the technical spirit of the present invention described above has been described in detail in a preferred embodiment, it should be noted that the above embodiment is for the purpose of description and not of limitation. In addition, those skilled in the art will understand that various embodiments are possible within the scope of the technical idea of the present invention. Therefore, the true technical protection scope of the present invention will be defined by the technical spirit of the appended claims.

Claims (5)

  1. In the bedsore treatment cream,
    Fry the natural ingredients consisting of brown ginseng, white paper, donkey, broiler, red peony, rhubarb, and raw sulfur in a pan, impregnate the roasted natural ingredients with vegetable oil for a predetermined time, remove the vegetable oil, and then remove specific ingredients. In order to obtain a result obtained by heating to a predetermined temperature in a certain time condition;
    Essential oils composed of Frankincence, Lavender, tea tree, or a combination thereof added to the resultant; And
    It includes; a moisturizing agent consisting of hyaluronic acid (hyaluronic acid) and EGF (epidermal growth factor) added after the essential oil is added to the resultant,
    The resulting product is 50% by weight, 5% by weight of the essential oil and 45% by weight of the moisturizing cream for the treatment of bedsores.
  2. delete
  3. delete
  4. delete
  5. In the process for the preparation of cream for bedsore treatment
    Roasting a natural material consisting of Hyunsam, white paper, Angelica, broiler, red peony, rhubarb, and raw sulfur in a pan (S101);
    Impregnating the roasted natural ingredients in vegetable oil (S102);
    Removing vegetable oil from the natural material (S103);
    Decoupling the natural material at a specific temperature and a specific time condition to remove a specific component from the natural material (S104);
    Adding essential oils composed of Frankincence, Lavender, tea tree, or a combination thereof to the resulted product (S105); And
    After the addition of the essential oil hyaluronic acid (hyaluronic acid) and EGF (epidermal growth factor) adding step (S106) comprising a cream for treating bedsores.
KR1020170185058A 2017-12-31 2017-12-31 Cream for treatment of pressure sore and method for manufacturing the same KR101974752B1 (en)

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20000052146A (en) * 1999-01-30 2000-08-16 이혜영 Cosmetics Composition with Tea Tree Oil
KR20140024879A (en) * 2011-04-26 2014-03-03 이노파막스, 인크. A composition of entacopone
KR101530574B1 (en) 2015-01-21 2015-06-22 서충은 Composition for treatment of bedsore and burn
KR101614659B1 (en) * 2015-10-12 2016-04-21 이충식 Manufacturing method for functional cosmetics
KR101809182B1 (en) 2016-08-09 2017-12-14 (주)화인메디 Composition for wound dressing with natural extract

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20000052146A (en) * 1999-01-30 2000-08-16 이혜영 Cosmetics Composition with Tea Tree Oil
KR20140024879A (en) * 2011-04-26 2014-03-03 이노파막스, 인크. A composition of entacopone
KR101530574B1 (en) 2015-01-21 2015-06-22 서충은 Composition for treatment of bedsore and burn
KR101614659B1 (en) * 2015-10-12 2016-04-21 이충식 Manufacturing method for functional cosmetics
KR101809182B1 (en) 2016-08-09 2017-12-14 (주)화인메디 Composition for wound dressing with natural extract

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
태을고B. 한국전통지식재산포탈-처방. 2007.12.06.* *

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