KR101917606B1 - Anti-aging cosmetic composition containing unriped citron-derived oil - Google Patents

Abstract

An anti-aging cosmetic composition based on the antimicrobial effect of ingredients derived from immature and phosphorous citron oil is disclosed. The present invention provides an anti-aging cosmetic composition derived from blueberry oil which can exert excellent effects in terms of application to anti-aging cosmetic composition based on excellent antibacterial effect by utilizing blue citrus oil extracted from immature and phosphorous citron extract can do.

Description

ANTI-AGING COSMETIC COMPOSITION CONTAINING UNRIPED CITRON-DERIVED OIL "

The present invention relates to an anti-aging cosmetic composition derived from a natural product, and more particularly to an anti-aging cosmetic composition containing a component derived from a blue-violet oil.

Skin is the primary barrier of the human body. It protects the internal organs of the body from external stimuli such as temperature and humidity changes, ultraviolet rays, and pollutants, and plays an important role in keeping the body homeostatic such as body temperature control. Such skin also becomes aged gradually with age as the other organs of the human body, and as a result, skin elasticity loss, keratinization, wrinkle formation, skin atrophy and the like appear. The causes of skin aging can be classified into internal factors such as gene mutation and tissue change, and external factors such as ultraviolet rays and humidity (Masamitsu Ichihashi, Fragrance Journal, Vol. 32, No. 5, 30). Particularly, the aging phenomenon caused by ultraviolet rays is called photoaging. In this photoaging phenomenon, active oxygen radicals are generated inside the cells by ultraviolet rays, and the active oxygen is converted into collagen, elastin, etc., which are elastic fibers of the dermal layer through an inflammatory reaction- (Fisher GJ et al., Nature, Vol. 379, 335-339) by decreasing the elasticity of the dermis layer, thereby promoting skin wrinkles (MMP-1, MMP-3, MMP- .

Therefore, efforts have been made to develop physiologically active substances to prevent skin aging and maintain healthy and elastic skin. For example, in 1995, trans-retinoic acid was approved by the US FDA as a treatment for photoaging skin, and since retinol, which has fewer side effects, began to be used in cosmetic ingredients in the mid and late 1990s, Cosmetics began to be released. Since then, female hormone-like substances and antioxidants extracted from various plants have been introduced into cosmetics as anti-aging cosmetic ingredients.

However, most of these cosmetic raw materials have various problems such as insufficient effect or induce skin side effects such as irritation and trouble. Accordingly, researches on raw materials having an anti-aging effect without causing side effects of skin have been actively conducted.

On the other hand, yuzu (citrus junos) is a fruit of Citrus junos, which is shaped like a ball with a diameter of 4 ~ 7cm. The color is light yellow and the skin is uneven. It has a good fragrance, a soft flesh but strong acidity. Origin is the upstream of Yangtze River in China. Kinds of blue, yellow, and real. It is produced in Korea, China, and Japan, and the Korean products are the most fragrant and the skin is thick. The main production areas in Korea are Goheung, Wando, Jangheung, Jindo, Gyeongsangnam-do, Geoje, Namhae and Tongyeong.

This citrus contains 3 times more vitamin C than lemon, and it is good for cold and skin beauty. It is also rich in organic acid, so it is effective in preventing aging and fatigue. In addition, vitamin B, saccharide and protein are more than other citrus fruits. Which is known to block cerebrovascular disorders and wind.

However, there is no known anti-aging cosmetic composition based on the antimicrobial effect of the components derived from the citron extract, especially blueberry oil, of the immature and exuding greenish appearance of citron fruit.

Accordingly, the present invention provides an anti-aging cosmetic composition based on the antimicrobial effect of the ingredients derived from immature and phosphorous citron oil.

The present invention also provides a method for producing blueberry oil for an anti-aging cosmetic composition in which extraction efficiency of the component derived from blueberry oil is maximized.

In order to solve the above-mentioned technical problems, the present invention provides an anti-aging cosmetic composition comprising as an active ingredient an immature, citron citron oil.

The present invention also provides an anti-aging cosmetic composition characterized in that the above-described sulfur blue oil is contained in an amount of 0.01 to 20% by weight based on the total weight of the composition.

According to another aspect of the present invention, there is provided a method for preparing a steam extractor, comprising the steps of: Subjecting the extractor to depressurization to automatically classify the raw material into heat steam and pressure; Discharging the mixed steam when the temperature of the extractor is 90 to 110 ° C; Depressurizing the extractor to raise the pressure to recover the oil-containing hydrogol residue when the temperature is between 100 and 120 ° C and the pressure is between 1.2 and 1.8 atmospheres; Introducing the residue into a separator to separate the oil; And storing the separated oil in a freezer for 12 hours to 3 days to collect unfrozen oil. The present invention also provides a method for manufacturing blueberry oil for an anti-aging cosmetic composition.

The present invention provides an anti-aging cosmetic composition derived from blueberry oil which can exert excellent effects in terms of application to anti-aging cosmetic composition based on excellent antibacterial effect by utilizing blue citrus oil extracted from immature and phosphorous citron extract can do.

Also, it is possible to provide a method for producing blueberry citrus oil for an anti-aging cosmetic composition in an optimum process which can maximize anti-aging effect through antibacterial effect as a method for producing blue citrus oil using a steam extractor.

BRIEF DESCRIPTION OF THE DRAWINGS FIG. 1 is a graph showing the results of MIC measurement of blueberry oil in the experimental examples of the present invention,
2 is a graph showing MIC measurement results of citron oil (steam distillation type) in the experimental example of the present invention,
3 is a graph showing the results of MIC measurement of citron oil (milking formula) in the experimental examples of the present invention,
4 is a graph showing the MIC measurement results of citrus seed oil in the experimental examples of the present invention.

Hereinafter, preferred embodiments of the present invention will be described in detail with reference to the accompanying drawings. DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS Hereinafter, the present invention will be described in detail with reference to the accompanying drawings.

The inventors of the present invention have made intensive studies on the application of the cosmetic composition to cosmetic compositions of the present invention. As a result, surprisingly, it has been found that cosmetic composition for antiaging agent based on excellent antimicrobial effect due to active ingredient of blueberry oil prepared through a specific process using steam extractor And the present invention has been achieved.

Accordingly, the present invention discloses a cosmetic composition for anti-aging comprising an immature and phosphorous citrus oil as an active ingredient.

In the present invention, it was confirmed that the composition according to the present invention has an excellent anti-aging activity because the growth inhibition concentration (MIC) for E. coli in the antimicrobial activity test of the blueberry oil oil is dramatically inhibited as a result of the microbial growth inhibition. The chelating agent used in the present invention was found to be greenish in appearance as an immature part of citron, and it was confirmed that the oil obtained by a specific method had an excellent anti-aging activity as compared with citron having apparent yellow color which is mature fruit.

In the present invention, the production of sulfur blue oil can be carried out by using a steam extractor. In this case, after the addition of the sulfur content of the citron extract, a series of steps such as preheating, depressurization, steam discharge, hydrosol residue recovery, oil separation, It is the most effective way to realize the anti-aging effect through antimicrobial activity when the surfactant is employed as a raw material.

That is, in the production of blueberry oil according to the present invention, the step of putting the blueberry fruit material into the steam extractor and sucking the steam to preheat; Subjecting the extractor to depressurization to automatically classify the raw material into heat steam and pressure; Discharging the mixed steam when the temperature of the extractor is 90 to 110 ° C; Depressurizing the extractor to raise the pressure to recover the oil-containing hydrogol residue when the temperature is between 100 and 120 ° C and the pressure is between 1.2 and 1.8 atmospheres; Introducing the residue into a separator to separate the oil; And storing the separated oil in a freezer for 12 hours to 3 days to collect unfrozen oil.

The anti-aging cosmetic composition may contain from 0.01 to 20% by weight, preferably from 0.1 to 10% by weight, more preferably from 0.5 to 5% by weight of the blue-purple citrus oil produced by the above-described method as an effective ingredient. If the content of the sulfuric acid oil is less than 0.01% by weight, the effect of improving the anti-aging property by the sulfuric acid oil may not be satisfactory, and if it exceeds 20% by weight, the increase of the effect may not be significant.

In addition, the anti-aging cosmetic composition may contain components commonly used in cosmetic compositions in addition to the above-described sulfur blue oil, and may include conventional additives such as stabilizers, solubilizers, vitamins, pigments and flavoring agents, and carriers.

The anti-aging cosmetic composition according to the present invention may be prepared in any formulations conventionally produced in the art and may be in the form of solutions, suspensions, emulsions, pastes, gels, creams, lotions, powders, soaps, , Oil, powder foundation, emulsion foundation, wax foundation, spray, and the like, but is not limited thereto. More specifically, the present invention relates to a cosmetic composition for cosmetics, such as softening longevity, convergent lotion, nutritional lotion, eye cream, serum, nutritional cream, massage cream, cleansing cream, cleansing lotion, cleansing foam, cleansing water, powder, essence, , Rinse, and the like.

When the formulation is a paste, cream or gel, an animal oil, a vegetable oil, a wax, a paraffin, a starch, a tracer, a cellulose derivative, polyethylene glycol, silicon, bentonite, silica, talc or zinc oxide may be used as a carrier component .

When the formulation is a powder or a spray, lactose, talc, silica, aluminum hydroxide, calcium silicate or polyamide powder may be used as a carrier component. In the case of a spray, in particular, chlorofluorohydrocarbons, propane / Butane, dimethyl ether, and the like.

When the formulation is a solution or an emulsion, a solvent, a solubilizing agent or an emulsifying agent is used as a carrier component, and examples thereof include water, ethanol, isopropanol, ethyl carbonate, ethyl acetate, benzyl alcohol, benzyl benzoate, propylene glycol, 3-butyl glycol oil, glycerol aliphatic ester, polyethylene glycol or fatty acid esters of sorbitan can be used.

When the formulation is a suspension, the carrier component may be a liquid diluent such as water, ethanol, propylene glycol, a suspension such as ethoxylated isostearyl alcohol, polyoxyethylene sorbitol ester, polyoxyethylene sorbitan ester, Cellulose, aluminum metahydroxide, bentonite, agar, trachant and the like may be used.

In addition, when the formulation is an interface-active agent-containing cleansing, the carrier component may include aliphatic alcohol sulfate, aliphatic alcohol ether sulfate, sulfosuccinic acid monoester, isethionate, imidazolinium derivative, methyltaurate, sarcosinate, fatty acid amide ether Alkylamido betaine, aliphatic alcohol, fatty acid glyceride, fatty acid diethanolamide, vegetable oil, lanolin derivative, ethoxylated glycerol fatty acid ester, and the like can be used.

Hereinafter, the present invention will be described in more detail with reference to Examples, Comparative Examples and Experimental Examples.

Example : Blue Citrus Oil Extract

Cheongju (harvested green fruits from Gohung, Jeonnam in the middle of September to October) and purchased from Yeonghung-based farming corporation in Goheung. Cut raw materials into 4 ~ 8 equal parts and put the raw materials into the extractor tank The steam extractor was operated for about 3 hours and 30 minutes to prepare an oil extract. The specific extraction method is as follows.

250kg of the cut raw material is put into the extractor tank, steam steam which is refined by the operation of the steam boiler is sucked into the extraction tank, and it is preheated for about 1 hour. At this time, decompression is applied to automatically sort the raw material into heat steam and pressure. When the temperature of the extraction tank reaches about 100 ° C, the steam discharge valve is opened to discharge the primary mixed steam to the outside for about 3 minutes to purify the steam in the extractor, and then the pressure is raised by applying the reduced pressure again, When the pressure is 1.5 kgf, open the steam extraction valve and the cooling water valve to start the oil separation operation. The oil separation process is performed for about 2 hours and 30 minutes. When the oil and the hydrazole are separated from the fractionation tank, about 200 kg of the hydrazole is obtained about 3 times, and the hydrazole residue containing the final oil is received through the separator Separate the hydrosol and oil. In order to obtain pure oil from the separated oil layer, firstly separated oil is kept in the freezer for one day and only unfrozen oil is collected.

Comparative Example  1: Yuzu oil extract

Citron oil was prepared in the same manner as in Example, except that citron fruit, apparently yellow, was used as a raw material in the examples.

Comparative Example  2: Milking formula  How to make citron oil by the method

Citron oil was prepared using the raw material used in Comparative Example 1 using a general milking machine.

Comparative Example  3: Milking formula  Method of manufacturing yuzu seed oil

In Comparative Example 2, yuzu seed oil was prepared in the same manner as in Comparative Example 2, except that citron was used instead of citron.

Experimental Example : Evaluation of antibacterial effect

In order to evaluate the antibacterial effect of the oil thus prepared, Escherichia coli coli (MIC) of microbial growth inhibition of DH5α. For this, each oil was mixed with the medium at the ratio of 10 wt%, 20 wt%, 30 wt%, 40 wt% and 50 wt%, and the O. D ₆₀₀ at 0 h and 24 h was checked to inhibit the growth of microorganisms The concentration (MIC) was confirmed. The results of MIC measurement of citron oil, citron oil (steam distillation type), citron oil (milking type) and citron seed oil are shown in FIGS. 1 to 4, respectively.

Referring to FIG. 1, in the case of blueberry oil prepared through a specific process using a steam extractor according to the present invention, when 10% by weight of blueberry oil was added, microorganisms were grown as much as the control E. coli, , 30, 40 and 50% by weight of blue-citrate oil was added, microorganisms were hardly grown. From these results, it can be confirmed that the blue-purple citrus oil produced according to the method of the present invention has an antibacterial effect that inhibits microbial growth when added in an amount of 10 wt% or more. For example, when the blueberry oil according to the present invention is applied to an emulsified formulation, it is preferable that at least 10% by weight (maximum 100% by weight) is used based on 100% by weight of the emulsion formulation in the cosmetic composition.

Next, referring to FIG. 2, the microorganism grew well on a medium supplemented with 10, 20, 30, 40 and 50% by weight citron oil by a control medium not containing citron oil as a result of MIC measurement Respectively. In the case of common citron oil, it is considered that the results of this experiment are obtained because it contains substances which promote the growth of microorganisms rather than the antibacterial effect.

Next, referring to FIG. 3, it was confirmed from the MIC measurement that citron oil obtained by the milking method showed that the microorganism grew better on the medium supplemented with citron oil than the control medium without the citron oil, Oil and so on.

Next, referring to FIG. 4, it was confirmed that microorganisms were grown well on the medium containing citron seed oil as a result of MIC measurement and also on the same reason as that of the citron oil.

As described above, when 10 to 50% by weight of citron oil (steam distillation type and milking type) and yuzu seed oil were added up to 10% by weight or more, microorganisms were grown. However, when 10% by weight or more of sulfur blue oil produced by steam distillation was added It was confirmed that the growth of microorganisms was inhibited. From this result, it is confirmed that the antibacterial substance which inhibits the growth of microorganisms is contained in the microcrystalline oil, so that the microorganism has antibacterial effect.

Hereinafter, an application example of the anti-aging cosmetic composition derived from blueberry oil according to the present invention will be described, but the present invention is not limited thereto.

Manufacturing example  1: Production of softened longevity

The softening oil having the composition shown in the following Table 1, including the above-prepared blue citron oil, was prepared according to the general method for producing lotion water.

Production Example 2: Production of nutritional cream

Nutritive creams comprising the above-prepared blue citron oil and having the composition shown in Table 2 below were prepared according to the general nutrition cream preparation method.

Production Example 3: Production of Nourishing Lotion

Nutritional lotion comprising the above-prepared spermatogonium oil and having the composition shown in the following Table 3 was prepared according to the general lotion preparation method.

Production Example 4: Production of Essence

Essences comprising the above-prepared blue syrup oil and having the composition shown in Table 4 below were prepared according to a general essence production method.

The preferred embodiments of the present invention have been described in detail with reference to the drawings. It will be understood by those of ordinary skill in the art that various changes in form and details may be made therein without departing from the spirit and scope of the present invention as defined by the appended claims.

Accordingly, the scope of the present invention is defined by the appended claims rather than the foregoing detailed description, and all changes or modifications derived from the meaning, range, and equivalence of the claims are included in the scope of the present invention Should be interpreted.

Claims (3)

delete delete Adding pre-fermented and fermented citrus raw material to a steam extractor and inhaling steam to preheat;
Subjecting the extractor to depressurization to automatically classify the raw material into heat steam and pressure;
Discharging the mixed steam when the temperature of the extractor is 90 to 110 ° C;
Depressurizing the extractor to raise the pressure to recover the oil-containing hydrogol residue when the temperature is between 100 and 120 ° C and the pressure is between 1.2 and 1.8 atmospheres;
Introducing the residue into a separator to separate the oil; And
Storing the separated oil in a freezer for 12 hours to 3 days to collect unfrozen oil;
Lt; / RTI >
Wherein the sulfur blue oil is contained in an amount of 0.1 to 10% by weight based on the total weight of the cosmetic composition.

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