KR101751585B1 - 데옥시콜린산 및 그의 염들의 제형물들 - Google Patents

데옥시콜린산 및 그의 염들의 제형물들 Download PDF

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Publication number
KR101751585B1
KR101751585B1 KR1020147006855A KR20147006855A KR101751585B1 KR 101751585 B1 KR101751585 B1 KR 101751585B1 KR 1020147006855 A KR1020147006855 A KR 1020147006855A KR 20147006855 A KR20147006855 A KR 20147006855A KR 101751585 B1 KR101751585 B1 KR 101751585B1
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South Korea
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deoxycholic acid
precipitation
salt
solution
sodium
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English (en)
Korean (ko)
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KR20150000448A (ko
Inventor
로버트 에밀 호지
제프리 더글라스 웹스터
로버트 엠. 모리어티
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키쎄라 바이오파마슈티컬즈 인코포레이티드
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Application filed by 키쎄라 바이오파마슈티컬즈 인코포레이티드 filed Critical 키쎄라 바이오파마슈티컬즈 인코포레이티드
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
KR1020147006855A 2011-08-23 2011-08-23 데옥시콜린산 및 그의 염들의 제형물들 Expired - Fee Related KR101751585B1 (ko)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2011/048806 WO2013028177A1 (en) 2011-08-23 2011-08-23 Formulations of deoxycholic acid and salts thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1020177016779A Division KR101919269B1 (ko) 2011-08-23 2011-08-23 데옥시콜린산 및 그의 염들의 제형물들

Publications (2)

Publication Number Publication Date
KR20150000448A KR20150000448A (ko) 2015-01-02
KR101751585B1 true KR101751585B1 (ko) 2017-06-27

Family

ID=45569726

Family Applications (5)

Application Number Title Priority Date Filing Date
KR1020177016779A Expired - Fee Related KR101919269B1 (ko) 2011-08-23 2011-08-23 데옥시콜린산 및 그의 염들의 제형물들
KR1020187032491A Expired - Fee Related KR102034606B1 (ko) 2011-08-23 2011-08-23 데옥시콜린산 및 그의 염들의 제형물들
KR1020147006855A Expired - Fee Related KR101751585B1 (ko) 2011-08-23 2011-08-23 데옥시콜린산 및 그의 염들의 제형물들
KR1020197030233A Active KR102073536B1 (ko) 2011-08-23 2011-08-23 데옥시콜린산 및 그의 염들의 제형물들
KR1020207002722A Ceased KR20200013103A (ko) 2011-08-23 2011-08-23 데옥시콜린산 및 그의 염들의 제형물들

Family Applications Before (2)

Application Number Title Priority Date Filing Date
KR1020177016779A Expired - Fee Related KR101919269B1 (ko) 2011-08-23 2011-08-23 데옥시콜린산 및 그의 염들의 제형물들
KR1020187032491A Expired - Fee Related KR102034606B1 (ko) 2011-08-23 2011-08-23 데옥시콜린산 및 그의 염들의 제형물들

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Application Number Title Priority Date Filing Date
KR1020197030233A Active KR102073536B1 (ko) 2011-08-23 2011-08-23 데옥시콜린산 및 그의 염들의 제형물들
KR1020207002722A Ceased KR20200013103A (ko) 2011-08-23 2011-08-23 데옥시콜린산 및 그의 염들의 제형물들

Country Status (18)

Country Link
JP (1) JP5919597B2 (enrdf_load_stackoverflow)
KR (5) KR101919269B1 (enrdf_load_stackoverflow)
CN (3) CN103826608A (enrdf_load_stackoverflow)
AU (3) AU2011375432B2 (enrdf_load_stackoverflow)
BR (1) BR112014000547B1 (enrdf_load_stackoverflow)
CA (1) CA2842177C (enrdf_load_stackoverflow)
CR (1) CR20140053A (enrdf_load_stackoverflow)
EA (1) EA029305B1 (enrdf_load_stackoverflow)
IL (1) IL230547A (enrdf_load_stackoverflow)
IN (1) IN2014CN02188A (enrdf_load_stackoverflow)
MX (1) MX350390B (enrdf_load_stackoverflow)
MY (1) MY184277A (enrdf_load_stackoverflow)
NZ (1) NZ620040A (enrdf_load_stackoverflow)
PH (2) PH12014500240A1 (enrdf_load_stackoverflow)
SG (1) SG2014013205A (enrdf_load_stackoverflow)
UA (1) UA113522C2 (enrdf_load_stackoverflow)
WO (1) WO2013028177A1 (enrdf_load_stackoverflow)
ZA (1) ZA201401027B (enrdf_load_stackoverflow)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102111346B1 (ko) 2019-08-20 2020-05-22 아영창 침전으로부터 안정한 소듐디옥시콜레이트를 포함하는 수용액상 조성물
KR20200068511A (ko) 2018-12-05 2020-06-15 송미희 지방 분해용 조성물 및 이를 포함하는 주사제 조성물
WO2020162685A1 (ko) 2019-02-08 2020-08-13 (주)제테마 국소 주사용 조성물
KR20220026068A (ko) 2020-08-25 2022-03-04 강명범 지방 분해용 주사제 조성물

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8101593B2 (en) 2009-03-03 2012-01-24 Kythera Biopharmaceuticals, Inc. Formulations of deoxycholic acid and salts thereof
CA2827643C (en) 2011-02-18 2019-05-07 Kythera Biopharmaceuticals, Inc. Treatment of submental fat
WO2017079700A1 (en) * 2015-11-04 2017-05-11 Kythera Biopharmaceuticals, Inc. Treatments of accumulated fat with deoxycholic acid and salts thereof
US20180078621A1 (en) * 2016-09-22 2018-03-22 Kyoung Lack Lee Composition for hypotonic lipolysis and manufacturing method thereof
KR101841193B1 (ko) * 2016-09-22 2018-03-22 이경락 저장성 지방 분해 조성물 및 그의 제조 방법
BR112020019192A2 (pt) * 2018-04-16 2021-01-05 Penmix Ltd. Composição farmacêutica que compreende ácido deoxicólico
CN116617160A (zh) * 2023-07-25 2023-08-22 山东则正医药技术有限公司 水性混悬液及制备方法、冻干粉及应用、脂肪消减注射剂
CN118005707A (zh) * 2024-01-18 2024-05-10 山东省食品药品检验研究院 一种脱氧胆酸钠晶型a及其制备方法和应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6417179B1 (en) 1998-10-13 2002-07-09 Craig G. Burkhart Ear wax solution

Family Cites Families (11)

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FR2754709B1 (fr) 1996-10-23 1999-03-05 Sanofi Sa Composition cosmetique contenant un antagoniste des recepteurs du neuropeptide gamma et alpha 2 antagonistes susceptibles d'etre incorpores dans une telle composition
WO2000004875A2 (en) * 1998-07-24 2000-02-03 Seo Hong Yoo Preparation of aqueous clear solution dosage forms with bile acids
US20050048126A1 (en) * 2000-12-22 2005-03-03 Barrett Rabinow Formulation to render an antimicrobial drug potent against organisms normally considered to be resistant to the drug
DE10361067A1 (de) * 2003-12-22 2005-07-14 Aventis Pharma Deutschland Gmbh Medikamentöse Lipolyse von Fettansammlungen
US20060127468A1 (en) * 2004-05-19 2006-06-15 Kolodney Michael S Methods and related compositions for reduction of fat and skin tightening
US7622130B2 (en) 2004-05-19 2009-11-24 Los Angeles Biomedical Research Institute at Harbor UCLA-Medical Center Methods and compositions for the non-surgical removal of fat
US7754230B2 (en) 2004-05-19 2010-07-13 The Regents Of The University Of California Methods and related compositions for reduction of fat
EP2356997A1 (en) 2005-06-06 2011-08-17 Georgetown University Compositions and methods for lipo modeling
TW201011755A (en) 2008-09-10 2010-03-16 Skymedi Corp Flash memory system and its data recovery method
JP5420946B2 (ja) * 2009-03-23 2014-02-19 富士フイルム株式会社 胆汁酸を含むミノキシジル水性組成物
EP2645099A1 (en) 2012-03-30 2013-10-02 Phares Pharmaceutical Research N.V. Biorelevant compositions

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6417179B1 (en) 1998-10-13 2002-07-09 Craig G. Burkhart Ear wax solution

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
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Dermatologic Surgery, 2009, 35, 792-803.

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20200068511A (ko) 2018-12-05 2020-06-15 송미희 지방 분해용 조성물 및 이를 포함하는 주사제 조성물
WO2020162685A1 (ko) 2019-02-08 2020-08-13 (주)제테마 국소 주사용 조성물
KR102111346B1 (ko) 2019-08-20 2020-05-22 아영창 침전으로부터 안정한 소듐디옥시콜레이트를 포함하는 수용액상 조성물
KR20220026068A (ko) 2020-08-25 2022-03-04 강명범 지방 분해용 주사제 조성물

Also Published As

Publication number Publication date
NZ620040A (en) 2016-06-24
SG2014013205A (en) 2014-05-29
KR20200013103A (ko) 2020-02-05
AU2011375432B2 (en) 2016-02-04
JP2014524467A (ja) 2014-09-22
PH12016501175A1 (en) 2017-12-11
KR101919269B1 (ko) 2018-11-15
AU2016202661B2 (en) 2018-02-22
KR20190119677A (ko) 2019-10-22
KR102034606B1 (ko) 2019-10-22
KR20170075016A (ko) 2017-06-30
CN103826608A (zh) 2014-05-28
EA029305B1 (ru) 2018-03-30
EA201490175A1 (ru) 2014-06-30
IL230547A0 (en) 2014-03-31
IN2014CN02188A (enrdf_load_stackoverflow) 2015-05-29
CA2842177C (en) 2016-07-19
KR20150000448A (ko) 2015-01-02
IL230547A (en) 2017-02-28
MY184277A (en) 2021-03-30
BR112014000547B1 (pt) 2021-11-09
UA113522C2 (xx) 2017-02-10
CR20140053A (es) 2014-06-12
MX350390B (es) 2017-09-06
CA2842177A1 (en) 2013-02-28
BR112014000547A2 (pt) 2017-02-14
CN108743522A (zh) 2018-11-06
KR20180123734A (ko) 2018-11-19
AU2018202807B2 (en) 2020-01-16
AU2011375432A1 (en) 2014-02-06
AU2016202661A1 (en) 2016-05-19
CN108619089A (zh) 2018-10-09
JP5919597B2 (ja) 2016-05-18
WO2013028177A1 (en) 2013-02-28
ZA201401027B (en) 2017-09-27
AU2018202807A1 (en) 2018-05-10
KR102073536B1 (ko) 2020-02-04
PH12014500240A1 (en) 2022-11-23
MX2014001495A (es) 2014-04-25
PH12016501175B1 (en) 2017-12-11

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