KR101660575B1 - 약한 분배성 크로마토그래피법 - Google Patents

약한 분배성 크로마토그래피법 Download PDF

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Publication number
KR101660575B1
KR101660575B1 KR1020137028820A KR20137028820A KR101660575B1 KR 101660575 B1 KR101660575 B1 KR 101660575B1 KR 1020137028820 A KR1020137028820 A KR 1020137028820A KR 20137028820 A KR20137028820 A KR 20137028820A KR 101660575 B1 KR101660575 B1 KR 101660575B1
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South Korea
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product
medium
protein
column
concentration
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Expired - Lifetime
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KR1020137028820A
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Korean (ko)
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KR20130128020A (ko
Inventor
폴 브라운
존 코프만
란가나단 고다바르티
팀 이스크라
브라이언 디 켈리
수레쉬 부눔
슈준 선
티아닝 위
제임스 에드워드 부스
메리 베스 스위저
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와이어쓰 엘엘씨
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/30—Partition chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/20—Partition-, reverse-phase or hydrophobic interaction chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/32—Bonded phase chromatography
    • B01D15/325—Reversed phase
    • B01D15/327—Reversed phase with hydrophobic interaction
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
    • B01D15/361—Ion-exchange
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
    • B01D15/3804—Affinity chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
    • B01D15/3804—Affinity chromatography
    • B01D15/3828—Ligand exchange chromatography, e.g. complexation, chelation or metal interaction chromatography

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
KR1020137028820A 2005-03-11 2006-03-10 약한 분배성 크로마토그래피법 Expired - Lifetime KR101660575B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US66043705P 2005-03-11 2005-03-11
US60/660,437 2005-03-11
PCT/US2006/008919 WO2006099308A2 (en) 2005-03-11 2006-03-10 A method of weak partitioning chromatography

Related Parent Applications (1)

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KR20077020848A Division KR101482791B1 (ko) 2005-03-11 2006-03-10 약한 분배성 크로마토그래피법

Publications (2)

Publication Number Publication Date
KR20130128020A KR20130128020A (ko) 2013-11-25
KR101660575B1 true KR101660575B1 (ko) 2016-09-27

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KR1020137028820A Expired - Lifetime KR101660575B1 (ko) 2005-03-11 2006-03-10 약한 분배성 크로마토그래피법
KR20077020848A Expired - Lifetime KR101482791B1 (ko) 2005-03-11 2006-03-10 약한 분배성 크로마토그래피법

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Country Status (21)

Country Link
US (3) US8067182B2 (https=)
EP (1) EP1869065B1 (https=)
JP (1) JP5199063B2 (https=)
KR (2) KR101660575B1 (https=)
CN (2) CN104610422A (https=)
AU (1) AU2006223180B2 (https=)
BR (1) BRPI0608584B8 (https=)
CA (1) CA2601062C (https=)
CR (1) CR9377A (https=)
DK (1) DK1869065T3 (https=)
ES (1) ES2797480T3 (https=)
HK (1) HK1210476A1 (https=)
HU (1) HUE049797T2 (https=)
IL (1) IL185687A (https=)
MX (1) MX2007011129A (https=)
NO (1) NO20074443L (https=)
PL (1) PL1869065T3 (https=)
PT (1) PT1869065T (https=)
RU (1) RU2457214C2 (https=)
SI (1) SI1869065T1 (https=)
WO (1) WO2006099308A2 (https=)

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SI1869065T1 (sl) 2020-08-31
WO2006099308A2 (en) 2006-09-21
KR20070121667A (ko) 2007-12-27
MX2007011129A (es) 2007-11-06
PT1869065T (pt) 2020-06-18
DK1869065T3 (da) 2020-06-08
BRPI0608584B1 (pt) 2018-02-06
NO20074443L (no) 2007-09-27
US20070054390A1 (en) 2007-03-08
EP1869065A2 (en) 2007-12-26
KR20130128020A (ko) 2013-11-25
US20070060741A1 (en) 2007-03-15
US9144755B2 (en) 2015-09-29
EP1869065B1 (en) 2020-05-06
AU2006223180A1 (en) 2006-09-21
JP5199063B2 (ja) 2013-05-15
IL185687A0 (en) 2008-01-06
HUE049797T2 (hu) 2020-10-28
RU2457214C2 (ru) 2012-07-27
ES2797480T3 (es) 2020-12-02
US20120138537A1 (en) 2012-06-07
WO2006099308A3 (en) 2007-10-25
CR9377A (es) 2008-02-21
CA2601062A1 (en) 2006-09-21
JP2008533473A (ja) 2008-08-21
IL185687A (en) 2015-05-31
CN104610422A (zh) 2015-05-13
CA2601062C (en) 2016-08-02
BRPI0608584A2 (pt) 2010-01-19
KR101482791B1 (ko) 2015-01-21
PL1869065T3 (pl) 2020-09-21
CN101175765A (zh) 2008-05-07
RU2007132851A (ru) 2009-04-20
BRPI0608584B8 (pt) 2021-05-25
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US8067182B2 (en) 2011-11-29
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