KR101537775B1 - template plate for One stop routine quality assurance and routine quality assurance method thereby - Google Patents

template plate for One stop routine quality assurance and routine quality assurance method thereby Download PDF

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KR101537775B1
KR101537775B1 KR1020140078210A KR20140078210A KR101537775B1 KR 101537775 B1 KR101537775 B1 KR 101537775B1 KR 1020140078210 A KR1020140078210 A KR 1020140078210A KR 20140078210 A KR20140078210 A KR 20140078210A KR 101537775 B1 KR101537775 B1 KR 101537775B1
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South Korea
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template
radiation
linear accelerator
epid
plate
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KR1020140078210A
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Korean (ko)
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임상욱
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고신대학교 산학협력단
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1048Monitoring, verifying, controlling systems and methods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1048Monitoring, verifying, controlling systems and methods
    • A61N5/1049Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1048Monitoring, verifying, controlling systems and methods
    • A61N5/1064Monitoring, verifying, controlling systems and methods for adjusting radiation treatment in response to monitoring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1048Monitoring, verifying, controlling systems and methods
    • A61N5/1075Monitoring, verifying, controlling systems and methods for testing, calibrating, or quality assurance of the radiation treatment apparatus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1077Beam delivery systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1048Monitoring, verifying, controlling systems and methods
    • A61N5/1075Monitoring, verifying, controlling systems and methods for testing, calibrating, or quality assurance of the radiation treatment apparatus
    • A61N2005/1076Monitoring, verifying, controlling systems and methods for testing, calibrating, or quality assurance of the radiation treatment apparatus using a dummy object placed in the radiation field, e.g. phantom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/10X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N2005/1085X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy characterised by the type of particles applied to the patient
    • A61N2005/1089Electrons

Abstract

The present invention relates to a method of controlling the accuracy of a linear accelerator using a template plate and a quality control template plate for the level management of a linear accelerator, which is located above the radiation irradiation path of the linear accelerator and the electronic portal imaging device (EPID) And a L-shaped radiopaque conductor is formed at a distance of 1 cm to 3 cm from the center of the template. The template plate for the accuracy management of the linear accelerator and the accuracy management of the linear accelerator using the template plate The method is a technical point. Accordingly, the present invention is advantageous in that it can be provided with a template plate in the middle of a radiation source and EPID, so that it is possible to build a daily precision management system that can increase the degree of agreement in comparison measurement between the EPID measurement result and the reference film.

Description

[0001] The present invention relates to a method for managing a linear accelerator using a template plate and a precision template plate,
The present invention relates to a method for managing the accuracy of a linear accelerator using a template plate and an accuracy management template plate for managing the accuracy of a linear accelerator, and a template plate for managing accuracy between a radiation source and an EPID, The present invention relates to a method for managing the accuracy of a linear accelerator using a template plate and a quality control template plate.
Radiation therapy uses radiation to treat disease, and a device called a LINAC Accelerator can be used. The linear accelerator accelerates electrons to emit high-energy radiation, and is capable of irradiating radiation according to the shape of a malignant or benign tumor located inside the human body. It is capable of various energy and high dose rate, .
In order to apply the linear accelerator to a patient, it is necessary to refer to the dose of radiation required for treating the patient's disease, the irradiation site of the radiation, and the time required for irradiation. If excessive radiation is projected onto the patient's body, normal cells of the patient may be destroyed, which may lead to deterioration of the patient's health.
Therefore, it is necessary to perform accurate dose verification before using a linear accelerator. It is necessary to check beforehand the operation precision such as whether the linear accelerator operates properly, the amount of the dose is controlled properly, and the radiation of the correct therapeutic dose is outputted, It is necessary to verify the dose as accurately as possible.
Therefore, before using the linear accelerator, it is necessary to manage the linear accelerator properly, control the radiation dose normally, and output the radiation of the correct treatment dose. This is called quality assurance (QA).
The American Medical Physics Association (AAPM) recommends periodic QA items, which are divided into two categories: dosimetry QA to measure radiation dose and mechanical QA to check for clearance and malfunction of mechanical motion.
Typical mechanical QA items include light / radiation field congruence, gantry / collimator angle indicators, a wedge position, a tray position, an applicator position, Applicator position, Field size indicators, Cross-hair centering, Treatment couch position indicators, Latching of wedge, Block tray ), Jaw symmetry, and Field light intensity.
Of course, a radiation check can also be performed. However, in the present invention, the light / radiation field congruence field size indicators and the jaw symmetry of the above items can be effectively QA .
Generally, a metal object such as a lead wire or a blade is accurately placed on a rectangular corner of a film, and the radiation is irradiated to compare the radiation pattern of the object with the object to determine whether the radiation irradiated by the rectangle and the rectangle It was a way to confirm. However, this method has a problem that it is difficult to manage various degrees of linear accelerators.
In addition, when the metallic object is placed outside the field, there is a problem that the image is not displayed on the film when the actual expected field is smaller than the position where the metallic object is placed.
Further, when the radiation dose profile is observed with an image, there is no reference line or reference point in the image, and the entire image is simply compared with the reference image.
In addition, there is no consideration of the symmetry of the beam, the flatness, the field size, the inconsistency of the center between the light field and the radiation field, and the precise quality control is not performed.
The present invention relates to a method for managing the accuracy of a linear accelerator using a template plate and an accuracy management template plate for managing accuracy of a linear accelerator capable of easily carrying out accurate accuracy management of a linear accelerator provided with a template plate on the EPID of a linear accelerator For the purpose of providing.
According to an aspect of the present invention, there is provided a lithographic projection apparatus comprising a linear accelerator and an electron portal imaging device (EPID) The present invention also provides a template plate for quality control of a linear accelerator wherein a radiopaque conductor is formed.
It is preferable that a grid and a cross line are formed in the template, and the radiopaque conductor is not formed in the central region of the template.
Preferably, the template is formed of an acrylic material, and the radiopaque conductor is formed of lead.
Further, it is preferable that a plastic phantom is further formed on the template.
In the meantime, the present invention provides a method for controlling a radiation dose, comprising the steps of: (1) placing a template plate for accuracy management comprising a template having a radiation irradiation path of a linear accelerator and an L-shaped radiopaque conductor on an EPID And a second step of comparing the dose profile of the film as a reference with a portal image obtained from the EPID including the image of the radiopaque conductor after the irradiation and analyzing it by a computer. The method for controlling the accuracy of a linear accelerator using a template control template is another technical point.
Preferably, the radiopaque conductor is not formed in a central region of the template, and the template plate is positioned to coincide with the center of the light field.
Further, in order to match the center of the light plate with the template plate, it is preferable that the center of the light field is aligned with the grid and the cross line on the template plate.
The accuracy management method of the linear accelerator using the accuracy management template plate may be a method of managing the degree of accuracy of the linear accelerator based on the field size error, the beam symmetry, the flatness, the correspondence between the light field and the radiation field, the collimator rotation check and the couch rotation couch rotation check.
The collimator rotation check and the couch rotation check may be performed by irradiating a radiation image at a predetermined angular interval to a portal image obtained from an EPID including an image of the radiopaque conductor, It is preferable to confirm whether or not the angles of the virtual crucifixes coincide with each other at predetermined angular intervals.
The present invention has an effect that a daily life degree management system capable of increasing the degree of agreement in comparison measurement between the EPID measurement result and the reference film can be constructed by providing a template plate in between the radiation source and the EPID.
Further, in order to obtain an accurate radiation dose, the present invention places a template plate for quality control of an acrylic template type on top of an EPID, and irradiates almost all the geometric information about the beam from the portal image after irradiation. So that it is possible to perform the quality control with one-stop without having to perform a separate setup again.
Therefore, the present invention facilitates the accuracy management of the linear accelerator, and the operation of the linear accelerator can be precisely implemented, thereby maximizing the therapeutic effect by irradiating the treatment area of the patient with an accurate dose.
1 is a schematic diagram of a template plate for quality control of a linear accelerator according to the present invention;
FIG. 2 is a schematic view showing a configuration in which a template plate for leveling the linear accelerator is disposed on the EPID according to the present invention. FIG.
3 is a diagram illustrating an image analysis process according to a quality control method of a linear accelerator according to the present invention;
FIG. 4 shows a comparison of the use of the EPID used quality management image and the film according to the present invention (right: film measurement, left: EPID measurement).
FIG. 5 is a view showing a radiation field change by the daily precision management method according to the present invention ((a) 6 MV photon beam, (b) 15 MV photon beam).
FIG. 6 is a diagram showing a symmetry error of a beam according to the daily accuracy management method according to the present invention ((a) 6 MV photon beam, (b) 15 MV photon beam).
FIG. 7 is a diagram showing the flatness of a beam according to the daily accuracy management method according to the present invention ((a) 6 MV photon beam, (b) 15 MV photon beam).
FIG. 8 is a diagram showing a congruence error between a light and a radiation according to the daily accuracy management method according to the present invention ((a) 6MV photon beam, (b) 15MV photon beam).
The present invention provides a day-to-day quality management system, wherein when measuring radiation with EPID, a template plate is provided in the middle of the radiation source and the EPID, and the template plate is L- And to establish a daily quality management system capable of enhancing the degree of agreement in comparison measurement between the EPID measurement result and the reference film.
The present invention proposes a routine quality assurance (QA) method for a linear accelerator (linac) based on a computer by devising a template plate for the quality control of a linear accelerator, It uses dosimetric properties of amorphous silicon electronic portal imaging device (EPID).
The template plate for quality control according to the present invention is formed into a rectangular shape with an acrylic material and is formed into a plate-like panel shape to form an acrylic template. The acrylic template is positioned above the EPID and the radiation path of the linear accelerator.
An L-shaped radiopaque conductor is further formed at a distance of 1 cm to 3 cm, preferably 2 cm, from the center of the acrylic template, so that an L-shaped pattern appears in the EPID portal image, Be a standard for quality control of geometric shapes.
That is, after the irradiation of radiation, the degree of the management is performed by comparing the dose profile of the film as a reference with the portal image obtained from the EPID including the image of the radiopaque conductor, .
Further, in order to improve image quality, it is preferable that a plate-shaped phantom of a plastic material is further formed on the template.
This method can confirm the symmetry of the photon beam from the linear accelerator, the flatness, the field size, and the correspondence between the light field and the radiation field at the same time.
Therefore, in order to obtain an accurate radiation dose, the present invention places a template plate for quality control of an acrylic template type on top of an EPID, and irradiates almost all the geometric information about the beam from the portal image after irradiation. It is possible to carry out the quality control with one-stop without having to perform a separate setup again.
In an embodiment of the present invention, an EPID measurement was compared with an EPID measurement measured in the present invention from ion ion chamber and film measurement devices to verify a quality assurance (QA) method, and the EPID measurement coincided with the film measurement.
The beam moduli of 6MV and 15MV energy were obtained for one month by the method according to the present invention and the QA tool using the EPID significantly reduced the time compared to the film test for the daily QA evaluation, .
Hereinafter, the present invention will be described in detail with reference to the accompanying drawings.
Generally, it is assumed that a light field and a radiation field coincide with each other in the radiation treatment using the quality management system according to the present invention. For this purpose, a ready-pack film is used for precision control test to match the light field and the radiation field, and a radiation field edge is used for the film cover Or display a radiopaque mark on the film, or make a pinhole through the cover and the film. In addition, the scale on the film is necessary to demonstrate a match between the light field and the radiation field for the QA processor.
On the other hand, EPID is becoming popular as a device for measuring the penetration dose and confirming online treatment. QA therapy using EPID in static or dynamic fields has been a subject of much research.
In the present invention, the dosimetric properties using the EPID reflect the geometry of the beam. The geometry of the beam for the measurement of the dose includes field size, beam symmetry, flatness, light field and radiation field Coincidence, collimator rotation, and couch rotation check.
The quality management system according to the present invention consists of an acrylic template and a program for analyzing DICOM images obtained from EPID. The acrylic template has a square of 25 x 25 cm and a thickness of 2 mm and is made of an acrylic plate into which a radiopaque L-shaped conductor is inserted.
The L-shaped leads are visible on x-ray films but are not generally visible, and the grid and crosshairs are depicted in an acrylic template. The acrylic template is suitably made to be placed on top of the EPID at a source-detector distance (SSD) of 100 cm.
The actual pixel pitch of the EPID used in one embodiment of the present invention was 0.784 mm and the effective pixel pitch was 0.749 mm when the template was placed on a 100 cm SSD.
On the other hand, the radiopaque conductors of the acrylic template are formed at a distance of 2 cm from the center line of the acrylic template, as shown in Fig. 1, in order to avoid interference with the profile scan.
Thus, for a portal image, the radiopaque wire acts as a landmark, and the program looks for the center of the light field in the EPID image or film image, or determines the edge of the light field.
Further, in the portal image, the edge of the radiation field is determined at 50% of the maximum pixel value, and the center of the radiation field is determined from this. The agreement between the light field and the radiation field is determined when the discrepancy between the center of the radiation field and the center of the light field is measured.
Program for the measurement method is to give assistance to be easily measured edge and the light field center of the radiation field at various SSD field with customer specification, the maximum size of 25x25cm 2 (radiation field from a 2x2cm 2, so 40x40cm 2, template Can be measured to a rectangular field size of 40 x 40 cm 2 .
The match between the light field and the radiation field is determined by comparing the distance between the edge of the radiation field and the edge of the light field, as described above.
EPID (PortalVision aS500; Varian Medical Systems, Palo Alto, Calif.) Used in one embodiment of the present invention has a resolution of 512 x 384 pixels and a pixel pitch of 0.78 x 0.78 mm (Fig. 2).
The Daily QA program was developed using the template plate for the quality control. The quality control items were designed considering field size error, beam symmetry, flatness, correspondence of light field and radiation field, collimator rotation check, couch rotation check (so-called star check) This can be evaluated simultaneously by analysis of the EPID image.
Here, the collimator rotation check and the couch rotation check (star check) are performed by irradiating a radiation image at a predetermined angular interval to a portal obtained from an EPID including an image of the radiopaque conductor, It is confirmed whether or not the angles of the virtual crucifixes coincide with each other at predetermined angular intervals based on the portal image.
Such a star check can calculate angles based on the L shape, for example, when the 45 degree angle is irradiated, the angle of the imaginary central cross drawn at 45 degree intervals You can check if they match.
Therefore, it is necessary to evaluate about the light / radiation field congruence field size indicators and Jaw symmetry as well as the star check among the machanical QA items required by the American Medical Physics Association (AAPM) It is easy to manage. Further, rotation check of the couch is also sufficiently possible if the template plate according to the present invention is placed on the couch. Therefore, most of the mechanical QA items recommended by the AAPM can be easily and accurately performed with one-stop.
On the other hand, the template plate is designed to coincide with the center of the light field, moving the center of the light field to a proper position by aligning the center of the light field with the grid and crosshatch on the template plate. The radiopaque conductor is not visible, but the cross-hair on the template plate is visible.
Then, the image transmitted from the EPID after irradiation is converted into the DICOM format (format) in the local computer. FIG. 3 shows an image processing process in a program according to an embodiment of the present invention.
First, the program uses the Roberts edge detection algorithm to locate the radiopaque conductor and determine the center of the light field. This determines the center field of the light field, which is transmitted as an L-shaped landmark. The landmarks are 2 cm from the center in the horizontal and vertical directions. This is because the distance to the center of the light in the conductor is constant and the center calculation of the lighter can be determined. 3C shows the width of the light field along the directions of X L and Y L of X L and Y L, respectively. X L and Y L have already been determined during setup.
Secondly, the present invention finds the edge of the radiation field from a DICOM image using an edge detection algorithm that measures the size of the radiation field. The center of radiation can be determined from half the size of its radiation field. This program allows you to compare the center position of the light field with the radiation field and their respective field sizes.
In order to confirm the reliability of the daily QA system developed in the present invention, the EPID measurement was compared with the measurement of the film (X-Omat V2; Kodak, New York, NY)
In order to test the QA system developed in the present invention, QA was performed daily for one month.
To obtain consistency of field size, field symmetry, field flatness, light field, and radiation field, photon beams with square fields of 6 MV and 15 MV were irradiated daily on template plates for one month. Portal images in the form of DICOM were analyzed by the aforementioned program.
As a result, the agreement between the EPID and the film measuring apparatus was less than 1% (Fig. 4). The precision of each item for the QA tool is shown in Table 1. This is sufficient to prove the beam of radiation for daily QA. For accuracy, use EPID with high resolution such as aS1000.
The change in the radiation field size of photon beams of 6 MV and 15 MV per day is shown in FIG. The width of the field with an area of 20 x 20 cm was measured daily except for the seventh and eighth days.
The daily variations of beam symmetry and flatness data for one month are shown in FIGS. 6 and 7, respectively. Figure 8 shows the day-to-day variation of agreement between the light field and the radiation field. There is an error of 3 mm on the 14th day, which seems to be due to the discrepancy between the center of the light field and the crosshairs in the template.
As described above, the template plate and the accuracy management method using the template plate for the accuracy management of the linear accelerator according to the present invention can analyze the beam symmetry, the flatness, the agreement between the light field and the radiation field, and the size of the portion through which the radiation is transmitted.
Also, the rotation error and SSD error of the field can be determined because the radiation-opaque conductor in the light field is used as an indirect landmark.
The time required to set up this image acquisition of photon energy is less than 10 minutes, and the image analysis time is less than 1 minute. The quality management time is drastically reduced.
The radiopaque conductors of the template plate for the quality control according to the present invention were not used in all ranges of edges or corners. That is, the L-shaped radiopaque conductor is suitable for use as a landmark because the distance of the conductor from the center is known accurately and the distance is fixed.
This lead is formed slightly shifted from the center and does not interfere with scanning to measure symmetry along the reticle. The advantage of using an L-shaped wire is that it can be used in any size rectangle.

Claims (12)

  1. Located on top of the radiation irradiation path of the linear accelerator and the electronic portal imaging device (EPID)
    Shaped template,
    Characterized in that an L-shaped radiopaque conductor is formed at a distance of 1 cm to 3 cm from the center of the template.
  2. The method according to claim 1,
    And a template plate for quality control of the linear accelerator.
  3. 3. The apparatus of claim 2, wherein the radiation-
    And the template is not formed in the central region of the template.
  4. 4. The method according to claim 3,
    Characterized in that the template plate is formed of an acrylic material.
  5. 5. The apparatus of claim 4, wherein the radiation-
    Wherein the template plate is formed of lead.
  6. The template plate according to claim 1, wherein a plate-shaped phantom is formed on the template.
  7. A first step of positioning a template plate for accuracy management, which comprises a template having a radiation irradiation path of a linear accelerator and an L-shaped radiopaque conductor on an EPID (electronic portal imaging device);
    And a second step of comparing the dose profile of a film to be a reference with a portal image obtained from an EPID including an image of the radiopaque conductor after irradiation with radiation, A method for managing the accuracy of a linear accelerator using a template control template.
  8. 8. The method of claim 7, wherein the radiopaque conductors are not formed in the central region of the template.
  9. 8. The method according to claim 7,
    And the position of the center of gravity of the linear accelerator is matched with the center of the light field.
  10. 10. The method of claim 9, wherein to match the center of the template plate with the light field,
    A method for managing the accuracy of a linear accelerator using a precision template plate characterized by centering a light field on a grid and a crosshatch on a template plate.
  11. 11. The method according to any one of claims 7 to 10,
    The quality control template includes a field size error, a beam symmetry, a flatness, a correspondence between a light field and a radiation field, a collimator rotation check, and a couch rotation check. A method of quality control of linear accelerators.
  12. 12. The method of claim 11, wherein the collimator rotation check and the couch rotation check are performed by:
    After irradiation at predetermined angular intervals, it is confirmed whether or not the angles of the imaginary central crosses based on the portal image obtained from the EPID including the images of the radiopaque conductors photographed respectively coincide with each other at predetermined angular intervals Wherein the accuracy of the accuracy of the linear accelerator using the quality control template plate is evaluated.
KR1020140078210A 2014-06-25 2014-06-25 template plate for One stop routine quality assurance and routine quality assurance method thereby KR101537775B1 (en)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6810108B2 (en) * 2001-11-02 2004-10-26 Siemens Medical Solutions Usa, Inc. System and method for positioning an electronic portal imaging device
KR20090081883A (en) * 2008-01-25 2009-07-29 가톨릭대학교 산학협력단 Phantom for quality assurance for image base radiation treatment device
US20130129255A1 (en) * 2010-07-14 2013-05-23 Tohoku University Signal-processing device and computer-readable recording medium with signal-processing program recorded thereon
KR20130059668A (en) * 2011-11-29 2013-06-07 서울대학교산학협력단 Multidimensional phantom for quality assurance of intensity modulated radiation therapy and stereotactic body radiation therapy

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6810108B2 (en) * 2001-11-02 2004-10-26 Siemens Medical Solutions Usa, Inc. System and method for positioning an electronic portal imaging device
KR20090081883A (en) * 2008-01-25 2009-07-29 가톨릭대학교 산학협력단 Phantom for quality assurance for image base radiation treatment device
US20130129255A1 (en) * 2010-07-14 2013-05-23 Tohoku University Signal-processing device and computer-readable recording medium with signal-processing program recorded thereon
KR20130059668A (en) * 2011-11-29 2013-06-07 서울대학교산학협력단 Multidimensional phantom for quality assurance of intensity modulated radiation therapy and stereotactic body radiation therapy

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