KR101411333B1 - Microfluidic Channel Having Heat Generating Member and Airborne Fine Particles Monitoring Apparatus Having the Same - Google Patents

Abstract

Disclosed are a microfluidic channel including a heat generating member and a fine particle monitoring apparatus including the same. The microfluidic channel is a microfluidic channel of a structure in which fine particles can flow through an inner part of the channel, wherein the width (W1) of the channel (212) is 300-700 micrometers, and the height (H) of the channel (212) is 50-300 micrometers; the channel (212) includes at least one curve change point or the bending point (213); and at least one heat generating member (224) is mounted on an abutment of the bending point (213) and the curve change point.

Description

TECHNICAL FIELD [0001] The present invention relates to a microfluidic channel including a heat generating member and a microfluidic channel monitoring apparatus having the microfluidic channel.

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a microfluidic channel including a heat generating member and a microparticle monitoring apparatus having the microfluidic channel. And a fine particle monitoring device having the fine flow channel.

Recently, as interest in indoor / outdoor air environment has increased, there is a growing need for atmospheric environment measurement and analysis system, and related technologies are also developing.

FIG. 1 is a perspective view and a partially enlarged view of a microfluidic system chip according to the prior art.

Referring to FIG. 1, a microfluidic system of a microchip unit is applied to a miniaturized system of an atmospheric environment measurement and analysis system. However, as shown in FIG. 1, the microfluidic system has the problem that particles adhere to the wall surface of the microchannel, and the sediment 14 is generated, resulting in a wall loss phenomenon.

The wall surface loss of the microfluidic channel causes problems such as clogging of the channel, which leads to a decrease in particle sorting and measurement efficiency, and a reduction in the reliability of the system in prolonged use.

In a miniaturized atmospheric environment measurement and analysis system, various methods have been utilized to solve the wall loss phenomenon in which particles adhere to channel walls of a microfluidic system.

Specifically, in order to remove particles adhering to the microfluidic channel, conventionally, an air jet or high frequency is used.

However, the above-mentioned particle removing method has a problem that can cause various physical damage such as wear and breakage of the microfluidic channel and microchip.

Japanese Patent Application Laid-Open No. 10-2011-0046475 (published May 04, 2011)

An object of the present invention is to provide a microfluidic channel in which particles adhere to an inner wall surface of a microfluidic channel to prevent a wall loss phenomenon in advance.

Still another object of the present invention is to provide a fine particle monitoring device having a fine flow channel having a structure capable of preventing the inner wall surface loss of a microfluidic channel in advance, thereby remarkably improving measurement accuracy and lifetime of the device will be.

To achieve these and other advantages and in accordance with the purpose of the present invention, as embodied and broadly described herein,

A microfluidic channel having a structure in which fine particles can flow through a channel,

The width of the channel is 300 to 700 탆,

The height of the channel is 50 to 300 탆,

Wherein the channel comprises at least one inflection point or bending point,

At least one heat generating member may be mounted in the vicinity of the inflection point and the bending point.

In addition,

And may be located in a circle centered on the inflection point or the bending point and having a width of the channel as a radius.

Also, the heat generating member may be heated to a temperature of 30 to 200 ° C, and the heat generating member may be a thermo-electronic module, a copper resistance wire, or a micro heater.

In this case, the thermal line width of the micro-heater may be 30 to 100 m, and more preferably, the thermal line width of the micro-heater may be 50 m.

The present invention can also provide a microparticle monitoring device comprising the microfluidic channel,

According to an aspect of the present invention, there is provided an apparatus for monitoring fine particles,

A micro virtual impactor that classifies fine particles according to the size of the particles;

A micro corona discharger for electrically charging fine particles; And

A particle collection plate for depositing fine particles and measuring the concentration of the fine particles;

. ≪ / RTI >

In this case, the micro-virtual impactor, the micro-corona discharge and the particle collection plate may be structured to communicate with each other by the micro flow channel.

In addition, the microvirtual impactor may be a structure that emits fine particles having a diameter of 190 nm or more to the outside.

In addition, the micro-virtual impactor, the micro-corona discharge and the particle collection plate may be formed on one plate-shaped plate.

In this case, a fine particle guide member including an air inlet and an air outlet may be further mounted on the plate-shaped plate.

The present invention can also provide a microparticle monitoring system comprising one or more of the microparticle monitoring devices.

As described above, the microchannel according to the present invention includes the heat generating member having a specific structure, thereby preventing particles from adhering to the inner wall of the microchannel due to the effect of particle thermophoresis, The loss phenomenon can be prevented in advance.

In addition, the apparatus for monitoring fine particles according to the present invention includes a fine flow channel having a structure capable of preventing the inner wall surface loss of the fine flow channel beforehand, thereby remarkably improving the measurement accuracy and the service life of the apparatus.

1 is a perspective view and a partially enlarged view of a microfluidic system chip according to the prior art.
Figs. 2 and 3 are schematic diagrams showing thermophoretic effects. Fig.
4 is a perspective view of a microfluidic system chip including a microfluidic channel unit according to the present invention.
5 is a perspective view showing the microfluidic channel portion shown in FIG.
6 is a sectional view taken along the line B-B 'in FIG.
7 is a perspective view showing the heat generating part shown in Fig.
8 is an enlarged view of a portion A in Fig.
9 is a schematic plan view of a microparticle monitoring apparatus according to another embodiment of the present invention.
10 is a perspective view showing a state in which the fine particle guide member is mounted on the fine particle monitoring apparatus shown in FIG.

Hereinafter, preferred embodiments of the present invention will be described in detail with reference to the accompanying drawings, but the scope of the present invention is not limited thereto. In the description of the present invention, a detailed description of known configurations will be omitted, and a detailed description of configurations that may unnecessarily obscure the gist of the present invention will be omitted.

2 and 3 are schematic views showing the thermophoretic effect.

Referring to these drawings, the thermophoretic effect is one of the kinematic characteristics of the fine particles 10, and is a phenomenon in which particles move due to a temperature gradient of a fluid in which particles are floating, .

Specifically, as shown in FIG. 2, the microparticles 10 flowing by the flow of the fluid draw a movement locus approaching the substrate 20 by a van der Waals force 21 . These fine particles 10 approach the thermophoretic effect region 40 generated by the heat generating member 30 mounted on the substrate 20. [ The microparticles 10 approaching the thermophoretic effect region 40 draw a movement trajectory 15 deviating from the substrate 20 without further approaching the surface of the substrate 20 by the thermionic force 41 .

3 is a cross-sectional schematic diagram showing the appearance of the fine particles 10 'flowing past the cylindrical member 20'.

Referring to FIG. 3, the fine particles 10 'flowing by the flow of the fluid approach the cylindrical member 20' by the inherent inertia. A heat generating member 30 'is mounted inside the cylindrical member 20', and the cylindrical member 20 'having such a structure generates a thermophoretic effect region 40'. The fine particles 10 'approaching the thermophoretic effect region 40' can not approach the surface of the cylindrical member 20 'any more due to the thermoactive force, and the movement locus 15' ').

Therefore, as shown in FIGS. 2 and 3, the fine particles 10 and 10 'are not adhered to the surface of the substrate 20 or the cylindrical member 20' by the thermophoretic effect. As a result, the thermophoretic effect can solve the problem that fine particles adhere to the microchannel wall surface in the microfluid system (not shown) to generate sediments.

The microfluidic channel and the microparticle monitoring device having the microfluidic channel according to the present invention use the thermophoretic effect, and a specific embodiment thereof will be described in detail below.

4 is a perspective view of a microfluidic system chip including a microfluidic channel unit according to an aspect of the present invention.

4, the microchannel channel assembly 200 according to the present embodiment includes a fine flow channel part 210 and a heat generating part 220. The microchannel channel assembly 200 is formed on a substrate 100, The fluid system chip 300 can be constructed.

FIG. 5 is a perspective view showing the microfluidic channel unit shown in FIG. 4. FIG. 6 is a sectional view taken along line B-B 'of FIG.

Referring to these drawings, the microfluidic channel unit 210 according to the present embodiment includes a channel 212 having a structure that includes at least one bending point 213 and fine particles (not shown) ≪ / RTI >

Specifically, the channel 212 may be formed in the substrate 211 having the upper cover 214 and the lower cover 215, and as shown in FIG. 6, a predetermined width W1 and a height H ). The width W1 and height H of the channel 212 may vary widely depending on the size of the fine particles flowing through the inside of the channel, And the height H of the channel 212 may be 50 to 300 占 퐉.

Fig. 7 is a perspective view showing the heat generating portion shown in Fig. 4, and Fig. 8 is an enlarged view of a portion A in Fig.

4, the heat generating portion 220 according to the present embodiment includes the electrodes 221 and 222, the patterned circuit 223, and the heat generating member 224, And may be formed on the substrate 100.

Specifically, the heat generating member 224 may be a thermo-electronic module, a copper resistance wire, or a micro heater.

The heat generating portion 224 may be formed on the substrate 100 and heated to a predetermined temperature capable of generating a thermophoretic effect. For example, the heat generating portion 224 may be heated to a temperature of 30 to 200 占 폚.

8, the heat generating portion 224 may be formed in the vicinity of the inflection points 2131 and 2132 of the channel 212. In addition, as shown in FIG.

The specific position of the heat generating portion 224 is not particularly limited as long as it is formed at a position adjacent to the bending points 2131 and 2132 of the channel 212 so as to generate a thermophoretic effect on the channel 212, May be located in a circle A1 centered on the first bending point 2131 of the channel 212 and having a width W1 of the channel 212 as a radius D, In order to further enhance the thermophoretic effect, heat is generated inside the circle A2 centered on the second bending point 2132 and having the width W1 of the channel 212 as the radius D A portion 224 can be further formed.

When the heat generating portion 224 is a microheater, the heat wire width W2 may be 30 to 100 占 퐉, and more preferably 50 占 퐉.

FIG. 9 is a schematic plan view of a microparticle monitoring apparatus according to another embodiment of the present invention, and FIG. 10 is a perspective view showing a microparticle guide member mounted on the microparticle monitoring apparatus shown in FIG. .

9, the apparatus for monitoring fine particles 400 according to the present embodiment includes a micro virtual impactor 410, a micro corona discharger 420, a particle collection plate 420, , 430) and may be a structure formed on one plate-like plate 401.

Specifically, the microvirtual impactor 410 can sort the fine particles according to the size of the particles 10, and can filter the fine particles having a predetermined size. 9, the microvirtual impactor 410 discharges particles having a relatively large inertia force of a particle introduced into the inlet to a central discharge portion arranged in a direction parallel to the inflow direction, Only the fine particles having a small inertial force and a predetermined size or smaller are selectively transferred to the next process, the micro corona igniter 420. For example, the microvirtual impactor 410 emits fine particles 11 having a diameter of 190 nm or more to the outside, and filters out fine particles having a diameter of 190 nm or less.

The microcorona disperser 420 serves to electrically charge the fine particles 12 and the particle collection plate 430 is formed by depositing the electrically charged fine particles 13 to form fine particles 13 It can perform the role of measuring the concentration.

In this case, the micro-virtual impactor 410, the micro-corona discharge 420, and the particle collection plate 430 may be structured to communicate with each other by the micro-flow channel 200 according to the present invention.

10, a fine particle guide member 500 including a fine particle inlet 510 and a fine particle outlet 520 may be further mounted on the plate-like plate 401. [

Particularly, the fine particle guide member 500 including the fine particle inlet 510 and the fine particle outlet 520 serves as a port for serving as an inlet and an outlet for air including fine particles. can do. Accordingly, the fine particle guide member 500 having such a structure can constitute a fine particle monitoring device by binding another pipe line to the fine particle inlet 510 and the fine particle outlet 520.

Therefore, the microchannel according to the present embodiment has a specific structure of the heat generating member, thereby preventing particles from adhering to the inner wall of the microchannel due to the effect of particle thermophoresis, It can be prevented in advance. In addition, the apparatus for monitoring fine particles according to the present invention has a fine flow channel having a structure capable of preventing the inner wall surface loss of the fine flow channel in advance, thereby remarkably improving the measurement accuracy and the life of the apparatus. .

In the foregoing detailed description of the present invention, only specific embodiments thereof have been described. It is to be understood, however, that the invention is not to be limited to the specific forms thereof, which are to be considered as being limited to the specific embodiments, but on the contrary, the intention is to cover all modifications, equivalents, and alternatives falling within the spirit and scope of the invention as defined by the appended claims. .

10, 10 ': fine particles
11: Fine particles having a diameter of 190 nm or more
12: Fine particles having a diameter of less than 190 nm
13: electrically charged fine particles
15, 15 ': movement locus 20: substrate
20 ': cylindrical member 21: van der waals force
30, 30 ': heat generating member 40, 40': thermophoretic effect region
41: heat hardening power 100: substrate
200: micro flow channel assembly
210: fine flow channel part 211: substrate
212: channel 213: bending point
2131: 1st bending point 2132: 2nd bending point
214: upper cover 215: lower cover
220: heat generating part 221, 222: electrode
223: patterned circuit 224: heat generating part
300: Microfluidic system chip 400: Microparticle monitoring device
401: substrate
410: micro virtual impactor
420: micro corona discharger < RTI ID = 0.0 >
430: Particle collection plate
500: fine particle guide member
510: fine particle inlet 520: fine particle outlet
A1: first region A2: second region

Claims (12)

A microfluidic channel having a structure in which fine particles can flow through a channel,
The width W1 of the channel 212 is 300 to 700 mu m,
The height H of the channel 212 is 50 to 300 탆,
The channel 212 includes one or more inflection points or bending points 213,
Wherein at least one heat generating member (224) is mounted in the vicinity of the inflection point and the bending point (213).
The method according to claim 1,
The heat generating member 224,
Is located within a circle (A1, A2) centered on the inflection point or bending point (2131, 2132) and having a width (W1) of the channel (212) as a radius.
The method according to claim 1,
The heat generating member 224,
Lt; RTI ID = 0.0 > 30 C < / RTI > to < RTI ID = 0.0 > 200 C. < / RTI >
The method according to claim 1,
The heat generating member 224,
Wherein the microfluidic channel is a thermo-electronic module, a copper resistance wire or a micro heater.
5. The method of claim 4,
Wherein the micro heater has a heat wire width (W2) of 30 to 100 占 퐉.
5. The method of claim 4,
Wherein the micro heater has a heat wire width (W2) of 50 占 퐉.
7. A microparticle monitoring device (400) comprising a microfluidic channel according to any one of claims 1 to 6,
A micro virtual impactor 410 for classifying the fine particles according to the size of the particles;
A micro corona discharger 420 for electrically charging fine particles; And
A particle collection plate 430 for depositing fine particles to measure the concentration of the fine particles;
Wherein the microparticle monitoring device comprises:
8. The method of claim 7,
The micro-virtual impactor 410, the micro-corona discharge 420, and the particle collection plate 430,
Wherein the microfluidic channel (200) is in communication with the microfluidic channel (200).
8. The method of claim 7,
Wherein the microvirtual impactor (410) emits fine particles having a diameter of 190 nm or more to the outside.
8. The method of claim 7,
The micro-virtual impactor 410, the micro-corona discharge 420, and the particle collection plate 430,
Is formed on one plate-like plate (401).
11. The method of claim 10,
Wherein a fine particle guide member (500) including a fine particle inlet (510) and a fine particle outlet (520) is further mounted on the plate-like plate (401).
10. A microparticle monitoring system, comprising at least one microparticle monitoring device according to claim 7.

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