KR101194261B1 - Cleansing composition for hair loss and promotion of hair growth without hypertension - Google Patents

Abstract

The present invention relates to a cleaning composition for preventing hair loss and promoting hair growth without increasing blood pressure, and more specifically, 7 to 13 parts by weight of earth, 6.0 to 7.5 parts by weight, hawthorn 6.0 to 7.0 parts by weight, 6.8 to 7.8 The composition of the present invention comprising parts by weight, peony 4.7-6.7 parts by weight, 3.5-5.5 parts by weight of neck and 3.5-5.0 parts by weight of neck reduces the risk of blood pressure increase that can be caused by the composition for preventing hair loss and promoting hair. When washing with the cleaning composition of the present invention, since the effect of promoting hair growth and preventing hair loss is exhibited, it can be usefully used as a cleaning composition for preventing hair loss and promoting hair growth without increasing blood pressure.

Description

Cleansing composition for hair loss and promotion of hair growth without hypertension}

The present invention relates to a cleaning composition for preventing hair loss without increasing blood pressure and promoting hair growth.

Hair loss has long been recognized as a common disease in middle-aged and older men. However, in modern society, not only men and middle-aged men but also women and even adolescents are suffering from hair loss. The explosive growth of the hair loss population regardless of age or gender is not only an individual problem, but also a social problem caused by the loss of self-confidence.

Human hair is derived from hair follicles present in the scalp. Because hair follicles originally form in the prenatal period and are no longer produced after birth, the number of hair follicles remains constant throughout adolescence and into adulthood, then gradually decreases from old age. There are about 100,000 to 150,000 human hairs, and each hair repeats its growth and extinction through a unique cycle of anagen stage, catagen stage, and telogen stage. This hair cycle is repeated over three to six years, and is known to be influenced by various factors such as season, disease, and stress in addition to genetic factors. However, even normal hair loses about 50 to 100 hairs a day on average, and in general, alopecia has less hair in the growing phase during the aforementioned hair cycle, while more hair in the degenerative or resting period results in abnormal hair loss. It refers to the increase.

In general, hair loss is caused by complex factors such as stress, environment, and genetic factors. Internally, the excretory organs, kidney and bladder, are deteriorated, and the sensation of circulation in the body rises due to incompatibility of hydration in the body. It causes the skin to swell, finally the elasticity to the hair roots, the tissue metabolism of the hair roots metabolism of the hair follicles and the contractile force of the hair root cells is reduced to cause hair loss.

Currently, many hair loss preventing agents or hair removal agents for preventing hair loss and promoting hair are commercially available, but there are still few drugs or technologies that can satisfy a therapeutic effect. The only drug approved by the US Food and Drug Administration (FDA) as a hair drug was minoxidil, which commercialized hair growth, a type of side effect that was originally developed as a treatment for hypertension and was the first to be recognized by the US federal government for the first time in the world. Medicine for baldness and alopecia. Another drug currently used is Propecia, which is based on hormonal theory of hair loss, and male hormones are converted to the metabolite dihydrotestosterone (DHT) under the action of 5-alpha-reductase. The substance is known to shrink and destroy hair follicles. The propecia inhibits DHT production by blocking 5-alpha-reductase, thereby slowing down the progression of masculine hair loss, and the effect of the drug is not in hair growth but in further prevention of hair loss.

In addition, examples of substances known to be effective in preventing hair and hair loss include cyclosporin derivatives (Korean Patent No. 10-0439467, Korean Patent No. 10-0695611), N-heterocyclic carboxylic acid and carbamate (Korean Patent No. 10). -2001-0052502), quinazolinone derivatives (Republic of Korea Patent Publication 10-1999-0023754), crysin 7-O-crotonate (Republic of Korea Patent Publication 10-2001-0009474) and 1,2-disubstituted benzenecarboxamide Compounds such as derivatives (Korean Patent Laid-Open Publication No. 10-1999-0037394) have been reported, and as a natural product with less side effects, Samsam extract (Korean Laid-open Patent Publication 10-2005-0102346), apricot seed oil (Korean Laid-Open Patent Publication 10-2004-) 0092755), Seokgok extract (Republic of Korea Patent Publication 10-2006-0008662), Baekduong Extract (Republic of Korea Patent Publication 10-2005-0102345), Indigo Extract (Republic of Korea Patent Publication 10-2005-0077310) and the situation mushroom extract (Republic of Korea registered special 10-0348155) has been reported, including a bar. The effects of these substances are insignificant, and long-term treatment is required to expect the effects, and hair loss progresses again when stopped. Therefore, in many cases lifelong use and side effects that can occur with prolonged use can also increase patient suffering. In addition, it is known that almost all anti-hair loss detergents on the market can cause an increase in blood pressure when statistical data are obtained by statistically obtaining blood pressure data of people using the anti-hair loss detergent currently in circulation.

In order to supplement and reinforce these problems, astringents and high-dose medicines and nature-friendly plant grains have been used in various ways. Typical examples include irises, oil, platinum, pomegranate, ume, baekhyeop, lump, samchiol, baekduong, schizandra, cornus, quince, gilt, quince, etc. It is used to develop commercial products.

Hair loss prevention plants have their own characteristics and functions, and shrink and make tissue cells surrounding hair roots appear to prevent and treat hair loss. In addition, aromatic medicinal plants, such as cloves, thyme, fennel, peppermint, fennel, sandalwood, quiche, benzoin, frankincense and other plant flavors, are used according to the preference of detergent users. Peppermint flavor is cold, and most of them are warm. In general, it has the property of penetrating blood penetrating blood, causing blood fever phenomenon and hematological hyperactivity, resulting in loss of strong blood circulation control. Shrinkage, aromatic plants, on the contrary, the action to strengthen the blood circulation is reversed, causing the physiological disharmony causing the nape of the neck and blood pressure rise.

Accordingly, the present inventors have solved the problem of blood pressure increase that may occur when using the composition for preventing hair loss or hair, and have studied to develop a composition that is effective in preventing hair loss or promoting hair. Approaches to oriental medical herbal medicines to stiffen the hair follicle cells firmly, medicinal composition of the cyanide component, a converging agent that reduces hair loss, and prevents blood pressure rise and lowers blood fever. The present invention has been completed by confirming the effect of inhibiting blood pressure rise and preventing hair loss or promoting hair of a cleaning agent including a composition including earth, bokbokyeong, hawthorn, natural powder, peony, peony, and neck.

It is an object of the present invention to provide a cleaning composition for preventing hair loss without increasing blood pressure and promoting hair growth.

It is an object of the present invention to provide a cleaning composition for improving hair loss and hair growth without increasing blood pressure.

In addition, another object of the present invention to provide a cleaning composition for preventing hair loss or promoting hair growth.

The composition of the present invention reduces the risk of blood pressure increase that can be caused by the hair loss prevention and hair promotion composition, and when washed with a cleaning agent containing the composition, shows the effect of promoting hair growth and preventing hair loss, thus increasing the blood pressure. It can be usefully used as a cleaning composition for preventing hair loss, and for promoting hair growth without.

1 is a graph showing the number of hair loss according to the number of hair washes after using the cleaning agent according to the present invention.
Figure 2 is a graph showing the number of hair loss according to the hair cleaner treatment time once a day after using the cleaning agent according to the present invention.
3 is a graph showing the hair effect of the cleaning agent according to the present invention.
Figure 4 is a graph showing the effect of inhibiting blood pressure increase after using the cleaning agent according to the present invention:
4A is a graph showing the change in systolic blood pressure after using the cleaning agent according to the present invention; And
4B is a graph showing changes in diastolic blood pressure after using the cleaning agent according to the present invention.

Hereinafter, the present invention will be described in detail.

The present invention provides a cleaning composition for improving hair loss and hair growth without increasing blood pressure.

The cleaning composition for improving hair loss and hair growth without increasing blood pressure according to the present invention preferably includes earth, bokbokyeong, hawthorn, cheonhwa, peony, bark, and neck and extract, more specifically 7 ~ 13 parts by weight of earth More preferably, 6.0 to 7.5 parts by weight, hawthorn 6.0 to 7.0 parts by weight, 6.8 to 7.8 parts by weight of cheonhwa, 4.7 to 6.7 parts by weight of peony, 3.5 to 5.5 parts by weight, and 3.5 to 5.0 parts by weight of neck and neck. . The composition has an effect of preventing the hair loss action that the hair root, which is a symptom of hair loss, escapes from the scalp.

In addition, it is preferable to further include any one from the group consisting of 15 to 19 parts by weight Jeonho, 7.5 to 11.5 parts by weight of confectionery, 6.8 to 7.8 parts by weight of Guangjihwang, 3.5 to 5.5 parts by weight of the lieutenant line, and 1.8 to 3.8 parts by weight of lettuce. It is not limited to this. The composition has an effect of preventing blood loss, which may occur when the hair growth promoting agent is used by removing the blood fever of the scalp.

In addition, glycerin 1.5-3.5 parts by weight, honey 1.5-3.5 parts by weight, potassium carbonate 2-4 parts by weight, sodium sulfate 1-3 parts by weight, calcium carbonate 1-3 parts by weight, magnesium carbonate 1-2 parts by weight, iron oxide 0.1- It is preferable to further include any one from the group consisting of 0.3 parts by weight, and 0.1 to 0.3 parts by weight of boric acid, but is not limited thereto. The composition has the effect of enhancing the affinity that the extract contained in the composition according to the present invention can act more effectively on the hair.

The amount of the raw material is preferably added to the composition ratio to maximize the physiological activity of the raw material combination by applying a similar method used in the field of oriental medicine after confirming the content to effectively increase the physiological activity for each raw material, but is not limited thereto. Do not.

As an extraction solvent of the extract contained in the cleaning composition for improving hair loss and hair growth without increasing blood pressure according to the present invention, it is preferable to use a solvent selected from water, a lower alcohol of C ₁ to C ₄ , or a mixed solvent thereof. Lower alcohol is preferably used ethanol or methanol, but is not limited thereto. The amount of the extraction solvent is preferably extracted by adding 2 to 15 times, preferably 5 to 10 times the amount of the earth, bokbokyeong, hawthorn, cheonhwa, peony, bark skin, and neck and weight. The extraction method may be an extraction method such as heat extraction, reflux cooling extraction, ultrasonic extraction, but is not limited thereto. Extraction temperature is preferably 30 ℃ to 100 ℃ but is not limited thereto. In addition, the extraction time is preferably 1 hour to 10 hours, but is not limited thereto. In addition, the number of extraction is preferably 1 to 5 times, and more preferably repeated extraction 2 to 3 times, but is not limited thereto. In addition, the drying is preferably reduced pressure drying, vacuum drying, boiling drying, spray drying or freeze drying, but is not limited thereto.

In a specific embodiment of the present invention, in order to measure the hair loss prevention effect of the cleaning agent comprising the composition extracted in <Examples 1, 2 and 3>, the number of hair loss according to the number of hair washes is counted, The number of hair loss decreases as the duration of using the cleaning agent containing the <Examples 1, 2 and 3> of the present invention is longer than the number of hairs when using the cleaning agent does not contain the extract of Example> I could confirm it. In addition, this tendency was higher the effect of the prevention of hair loss the more the number of times to wash a day (see Fig. 1 and Table 1). In addition, in order to measure the effect of the prevention of hair loss according to the change in the use time of the cleaning agent, the number of hair loss after using the cleaning agent containing the extract of <Examples 1, 2 and 3> of the present invention for 2 to 10 minutes As a result of counting, as the time to use the cleaning agent increased from 2 minutes to 10 minutes, the number of hair loss was reduced, this result was confirmed that the longer the use of the cleaning agent is more effective (Fig. 2 and Table 2 Reference).

In addition, in a specific embodiment of the present invention, in order to measure the hair promoting effect of the cleaning agent comprising the extracts of <Examples 1, 2 and 3> of the present invention, after using the cleaning agent, the observed hair was observed. It was observed that the longer the duration of using the increase the effect of the hair (see Fig. 3 and Table 3).

In addition, in order to measure the blood pressure increase prevention effect of the cleaning agent containing the extracts of Examples 1, 2 and 3 of the present invention in a specific embodiment of the present invention, the change in blood pressure was measured. An increase in blood pressure was observed when the control detergent containing no extracts of Examples 1, 2 and 3 of the present invention was used, but when using a detergent containing extracts of Examples 1, 2 and 3 of the present invention, No rise was observed (see Figure 4, Table 4 and Table 5).

Therefore, the earth 7-13 parts by weight of the present invention, 6.0-7.5 parts by weight, bokbok 6.0-7.0 parts by weight, 6.8-7.8 parts by weight of hwahwa, 4.7-6.7 parts by weight of peony, 3.5-5.5 parts by weight of bark skin, and A cleaning agent containing neck and 3.5 to 5.0 parts by weight can be usefully used as a cleaning composition for improving hair loss and hair growth without increasing blood pressure.

The compositions of the present invention can be formulated in a variety of forms, including soaps, shampoos, rinses.

Detergent included in the cleaning composition for improving hair loss and hair growth without increasing blood pressure according to the present invention is preferably used raw materials included in a conventional shampoo or rinse composition, surfactant, oil, humectant, thickening / formulation stabilizer, pH More preferably, but not limited to, a modifier, a dispersion stabilizer, a sunscreen, a fragrance or a preservative. The amount of the extract according to the present invention contained in the detergent is preferably 1 to 10 parts by weight, more preferably 2 to 5 parts by weight based on 100 parts by weight of the total composition.

The cleaning composition for improving hair loss and hair growth without increasing blood pressure according to the present invention includes 26.4 parts by weight of purified water, 0.2 parts by weight of thickener, 0.5 parts by weight of metal ion sequestrant, 0.5 parts by weight of pH adjuster, 30.0 parts by weight of anionic surfactant, and amphoteric properties. A general shampoo base that prevents and protects hair from damage, including 10.0 parts by weight of surfactant, 5.0 parts by weight of nonionic surfactant, 2.0 parts by weight of scalp nutrient, 1.5 parts by weight of disinfectant, 2.8 parts by weight of moisturizer, and 0.35 parts of flavoring agent. It is preferable to include 3 parts by weight of the extract according to the invention. Here, purified water is more pure water made by filtering a constant (tap water) by chemical and physical methods.

The thickener is used to form a gel type at room temperature, it is preferable that 0.1 parts by weight of polyquaternium-10 and 0.1 parts by weight of sodium chloride (NaCl) are added. In addition, calcium and magnesium mixed in hard water are used to make bubbles smoothly without the formation of sticky scum, which is produced by chemical reactions with soap components. An ion blocker (Sequestering Agent) is added. Here, it is preferable that 0.05 weight part of sodium ethylene diamine tetraacetate is added as a metal ion blocking agent.

On the other hand, it is preferable to adjust the pH of the whole composition to pH 5.5-6.0 by adding 0.05 weight part of citric acid (citric acid) as a pH adjuster. It is preferred that 0.35 parts by weight of perfume is added as a flavoring agent of the shampoo composition.

Meanwhile, 45.0 parts by weight of the surfactant includes an anionic surfactant, an amphoteric surfactant, and a nonionic surfactant. Here, Anionic Surfactant is 30.0 parts by weight of Ammonium Laureth Sulfate, Amphoteric Surfactant is an ingredient extracted from coconut, has excellent cleaning power, gives a rich and soft foam. 10.0 parts by weight of Cocamidopropyl Betaine, a nonionic surfactant that can give a soft feeling to the skin after use, is a clear yellow liquid extracted from synthetic hair conditioner coconut oil as a foam enhancer. It is preferably added in 5.0 parts by weight of cocamide DEA.

The blood pressure increase without hair loss and hair growth improvement composition according to the present invention can be formulated as a soap.

Hair loss and hair growth improvement cleaning composition according to the present invention can be prepared by including the extract according to the present invention on a soap base, it can be prepared by including a skin moisturizer, emulsifier, water softener and the like as an additive. As the soap base material, vegetable oils such as palm oil, palm oil, soybean oil, perm oil, olive oil, palm kernels, or animal oils such as tallow, pork, sunny and fish oils can be used, and the skin moisturizing agent is glycerin, erythritol and polyethylene glycol. , Propylene glycol, butylene glycol, pentylene glycol, hexyl glycol, isopropyl myristate, silicone derivatives, aloe vera, sorbitol and the like can be used, the emulsifiers such as natural oils, wax fatty alcohols, hydrocarbons, natural plant extracts, etc. May be used, and tetrasodium idieti may be used as the water softener. The soap composition of the present invention may further include an antimicrobial agent, a dispersant, a foam inhibitor, a solvent, a scale inhibitor, a corrosion inhibitor, a perfume, a pigment, a metal ion sequestrant, an antioxidant, a preservative, and the like as an additive.

In the cleaning composition for improving hair loss and hair growth without increasing blood pressure according to the present invention, a soap base or an additive may be included in an amount generally used in the art, and the soap base is generally based on the total content of the soap composition. 99.9 parts by weight to 50 parts by weight may be added, and the additive may be added in an amount of 1 to 10 parts by weight.

In addition, the present invention provides a cleaning composition for preventing hair loss or promoting hair growth.

In a specific embodiment of the present invention, after using the cleaning agent comprising the extracts of <Examples 1, 2 and 3> of the present invention, the number of hair loss according to the use time and the number of times decreased, and also after using the cleaning agent according to the present invention, the hair Since the effect is confirmed, it can be usefully used as a cleaning composition for preventing hair loss or promoting hair growth.

Hair loss prevention or hair growth promoting cleaning composition according to the present invention preferably contains earth, bokbokyeong, hawthorn, cheonhwabun, peony, bark, and neck and extract, more specifically 7 ~ 13 parts by weight, earth More preferably, it comprises 6.0-7.5 parts by weight of Fuling, 6.0-7.0 parts by weight of hawthorn, 6.8-7.8 parts by weight of cheonhwa, 4.7-6.7 parts by weight of peony, 3.5-5.5 parts by weight of bark skin, and 3.5-5.0 parts by weight of neck. In addition, it is preferable to further include any one from the group consisting of 15 to 19 parts by weight Jeonho, 7.5 to 11.5 parts by weight of confectionery, 6.8 to 7.8 parts by weight of Guangjihwang, 3.5 to 5.5 parts by weight of the lieutenant line, and 1.8 to 3.8 parts by weight of lettuce. It is not limited to this. Further, in the cleaning composition for preventing hair loss or promoting hair growth of the present invention, glycerin 1.5 to 3.5 parts by weight, honey 1.5 to 3.5 parts by weight, potassium carbonate 2 to 4 parts by weight, sodium sulfate 1 to 3 parts by weight, calcium carbonate 1 to It is preferable to further include any one from the group consisting of 3 parts by weight, 1-2 parts by weight of magnesium carbonate, 0.1-0.3 parts by weight of iron oxide, and 0.1-0.3 parts by weight of boric acid, but is not limited thereto.

As an extraction solvent of the extract included in the hair loss preventing or hair growth promoting cleaning composition according to the present invention, it is preferable to use a solvent selected from water, a lower alcohol of C ₁ to C ₄ or a mixed solvent thereof, and a higher lower alcohol. Silver ethanol or methanol is preferably used, but is not limited thereto. The amount of the extraction solvent is preferably extracted by adding 2 to 15 times, preferably 5 to 10 times the amount of the earth, bokbokyeong, hawthorn, cheonhwa, peony, bark skin, and neck and weight. The extraction method may be an extraction method such as heat extraction, reflux cooling extraction, ultrasonic extraction, but is not limited thereto. Extraction temperature is preferably 30 ℃ to 100 ℃ but is not limited thereto. In addition, the extraction time is preferably 1 hour to 10 hours, but is not limited thereto. In addition, the number of extraction is preferably 1 to 5 times, and more preferably repeated extraction 2 to 3 times, but is not limited thereto. In addition, the drying is preferably reduced pressure drying, vacuum drying, boiling drying, spray drying or freeze drying, but is not limited thereto.

Hereinafter, the present invention will be described in detail by Examples, Experimental Examples and Preparation Examples. However, the following Examples, Experimental Examples and Preparation Examples are merely illustrative of the present invention, and the content of the present invention is not limited to the following Examples, Experimental Examples, and Preparation Examples.

< Example  1> Preparation of herbal composition 1

Jeon 15 parts by weight, earth weight 7 parts by weight, male confectionery 7.5 parts by weight, Tobokyeong 6.5 parts by weight, sunshade 6 parts by weight, hwahwa by weight 6.8 parts by weight, dried Guhwang 6.8 parts by weight, peony 4.7 parts by weight, bark skin 3.5 parts by weight, lieutenant 3.5 Parts by weight, neck and 3.5 parts by weight, epidermis 1.8 parts by weight, glycerin 1.5 to 3.5 parts by weight, honey 1.5 to 3.5 parts by weight, potassium carbonate by 2 to 4 parts by weight, sodium sulfate by 1 to 3 parts by weight, calcium carbonate by 1 to 3 parts by weight, To 1-2 parts by weight of magnesium carbonate, 0.1 to 0.3 parts by weight of iron oxide, and 0.1 to 0.3 parts by weight of boric acid, water is added four times, and then heated at 100 ° C. for 3 hours to obtain an extract, which is sterilized and dried The composition was prepared.

< Example  2> Preparation of herbal composition 2

Jeonho 17 parts by weight, earth 10 parts by weight, male confectionery 9.5 parts by weight, Tobokyeong 7 parts by weight, sunshade 8 parts by weight, hwahwa by weight 7.3 parts by weight, dry yellow 7.3 parts by weight, peony 5.7 parts by weight, neck skin 4.5 parts by weight, lieutenant 4.5 Parts by weight, neck and 4.3 parts by weight, white and white skin 2.8 parts by weight, glycerin 1.5 to 3.5 parts by weight, honey 1.5 to 3.5 parts by weight, potassium carbonate 2 to 4 parts by weight, sodium sulfate by 1 to 3 parts by weight, calcium carbonate by 1 to 3 parts by weight, To 1-2 parts by weight of magnesium carbonate, 0.1 to 0.3 parts by weight of iron oxide, and 0.1 to 0.3 parts by weight of boric acid, water is added four times, and then heated at 100 ° C. for 3 hours to obtain an extract, which is sterilized and dried The composition was prepared.

< Example  3> Preparation of herbal composition 3

Jeonho 19 parts by weight, earth 13 parts by weight, male confectionery 11.5 parts by weight, Tobokyeong 7.5 parts by weight, mountain sand 10 parts by weight, hwahwa 7.8 parts by weight, dried Guangji 7.8 parts by weight, peony 6.7 parts by weight, bark skin 5.5 parts by weight, lieutenant 5.5 Parts by weight, neck and 5.0 parts by weight, skin and skin 3.8 parts by weight, glycerin 1.5-3.5 parts by weight, honey 1.5-3.5 parts, potassium carbonate 2-4 parts, sodium sulfate 1-3 parts, calcium carbonate 1-3 parts, To 1-2 parts by weight of magnesium carbonate, 0.1 to 0.3 parts by weight of iron oxide, and 0.1 to 0.3 parts by weight of boric acid, water is added four times, and then heated at 100 ° C. for 3 hours to obtain an extract, which is sterilized and dried The composition was prepared.

< Experimental Example  1> Measure hair loss prevention effect

In order to measure the hair loss prevention effect of each extract prepared in <Example> 1, 2 and 3, respectively, 10 ~ twice a day spray for cleaning agent containing the extract of <Examples 1, 2 and 3> After 15 cc was injected into the scalp, the number of hairs to be bald was counted. As a control for this, cleaning sprays containing no extract of <Examples 1, 2 and 3> were used.

As a result, as shown in Figure 1 and Table 1, 30 adults (recruitment from the IT, BT start-up nursery center, Wonkwang University, Iksan-si, Jeonbuk-si), 40 ~ After use in adults in their 60s, 15 males and 15 females), the number of hair loss was reduced compared to the control group. As the number of washings per day increased, the hair loss prevention effect was remarkably observed as the period of using the cleaning agent increased (FIG. 1 and Table 1).

Moreover, the hair loss prevention effect of the washing | cleaning agent containing the composition of this invention was measured according to the hair-cleaning agent treatment time change. As a result of counting the number of hair loss after using the cleaning agent containing the extracts of Examples 1, 2 and 3 for 2 to 10 minutes, the number of hair loss decreased as the use time of the cleaning agent was longer from 2 to 10 minutes. In addition, this effect was observed to be more effective the longer the use of the cleaning agent (Fig. 2 and Table 2).

Depilation water according to the number of hair washes Control group &Lt; Example 1 >
extract <Example 2>
extract <Example 3>
extract 1 day later

1 time cleaning 135 88 90 89 2 washes 138 78 80 82 3 washes 125 68 67 69 2 days later

1 time cleaning 142 69 72 70 2 washes 138 58 57 61 3 washes 120 37 40 39 3 days later

1 time cleaning 134 55 58 57 2 washes 125 49 52 47 3 washes 120 34 36 35 5 days later

1 time cleaning 142 35 38 35 2 washes 130 36 39 40 3 washes 128 26 34 35

Hair loss prevention effect of each extract of <Examples 1, 2 and 3> (hair loss hair number) Control group &Lt; Example 1 >
extract <Example 2>
extract <Example 3>
extract 1 day later
Clean after 2 minutes 140 80 83 85 4 minutes later 135 60 64 60 6 minutes later 130 50 55 57 10 minutes later 120 40 45 42
2 days later

Clean after 2 minutes 140 60 68 62 4 minutes later 132 50 55 52 6 minutes later 120 60 65 63 10 minutes later 125 40 46 45
3 days later
Clean after 2 minutes 130 60 63 64 4 minutes later 120 50 52 47 6 minutes later 128 40 38 42 10 minutes later 132 30 32 35
4 days later

Clean after 2 minutes 142 30 31 34 4 minutes later 134 40 39 40 6 minutes later 135 40 38 42 10 minutes later 145 30 33 31
5 days later

Clean after 2 minutes 137 50 45 48 4 minutes later 134 40 42 46 6 minutes later 128 30 32 33 10 minutes later 136 20 25 26

< Experimental Example  2> hair promoting effect

In order to measure the hair promoting effect of each extract prepared in the <Examples 1, 2 and 3>, after spraying a spray for cleaning agent containing the extract of the example twice a day 10-15cc to the scalp, 1 Hair was observed for ˜8 months. As a control for this, cleaning sprays containing no extract of <Examples 1, 2 and 3> were used in 30 of <Experimental Example 1>.

As a result, as shown in Figure 2 and Table 3, when using the cleaning agent does not contain the <Examples 1, 2 and 3> extract of the present invention, no change in hair was observed, <Example 1, When the cleaning agents containing the extracts of 2 and 3> were used, it was observed that the hair promoting effect was observed (Fig. 2 and Table 3).

Hair promoting effect (%) of each extract of <Examples 1, 2 and 3> After 1 month 3 months later 6 months later 8 months later Control group 0 0 0 0 Example 1 Extract 0 12 22 35 Example 2 Extract 0 10 20 30 Example 3 Extract 0 11 21 34

< Experimental Example  3> Blood pressure increase prevention effect measurement

In order to solve the problem of the increase in blood pressure observed when the hair loss prevention and hair promoting cleaners were used, the blood pressure change was observed after using the extracts prepared in Examples 1, 2 and 3 of the present invention. After spraying 10-15 cc twice daily with a spray for cleaning agents each containing the extracts of <Examples 1, 2 and 3>, the blood pressure was observed. As a control for this, cleaning sprays containing no extract of <Examples 1, 2 and 3> were used.

As a result, as shown in Figure 4 and Table 4, when using the cleaning agent containing the <Example 1, 2 and 3> extract of the present invention showed a blood pressure lower than, or slightly elevated than the general systolic blood pressure, In the case of using the cleaning agent used as a control, the longer the use time of the cleaning agent, the longer the period of use, it was observed that the blood pressure gradually increased (Fig. 4 and Table 4). In addition, these results were similarly observed in the control group and the results of using the cleaning agent containing the extracts of <Example 1, 2 and 3> based on the diastolic blood pressure of 80 mm (Table 5).

Inhibitory effect on the systolic blood pressure increase of the cleaning agent containing the extracts of <Examples 1, 2 and 3> Control group &Lt; Example 1 >
extract <Example 2>
extract <Example 3>
extract 1 day later
6 minutes later 125 112 115 118 10 minutes later 130 115 117 120 2 days later
6 minutes later 129 108 112 112 10 minutes later 142 117 116 118 3 days later
6 minutes later 132 120 118 120 10 minutes later 145 125 126 128 4 days later
6 minutes later 138 118 117 118 10 minutes later 145 126 127 129 5 days later
6 minutes later 142 115 118 120 10 minutes later 146 131 130 132

Inhibitory Effect of Diastolic Blood Pressure Rise of Cleaning Agents Containing Extracts of <Examples 1, 2 and 3> Control group &Lt; Example 1 >
extract <Example 2>
extract <Example 3>
extract 1 day later
6 minutes later 83 75 74 78 10 minutes later 84 77 79 79 2 days later
6 minutes later 82 75 74 75 10 minutes later 91 78 79 76 3 days later
6 minutes later 84 78 77 79 10 minutes later 93 85 86 84 4 days later
6 minutes later 96 74 73 75 10 minutes later 98 86 85 88 5 days later
6 minutes later 97 78 77 79 10 minutes later 99 89 87 88

The preparation examples for the compositions of the present invention are given below.

< Manufacturing example  1> Preparation of Cleaning Agent

<1-1> Preparation of Shampoo

   Example 1 1.0 part by weight of extract

Silicone oil (100,000 cst) 1.5 parts by weight

Silicone gum 1.0 parts by weight

12.0 parts by weight of ammonium lauryl sulfate

Polyoxyethylene lauryl ammonium sulfate 4.0 parts by weight

Cocamide Diey 3.0 parts by weight

1.0 part by weight of glycol stearate

Lauramid Lepofilbetaine 3.0 parts by weight

Lauro Ampocarboxyglycinate 3.0 parts by weight

Color, flavor and preservatives

Amount of distilled water

<1-2> Preparation of soap

<Example 2> 3.0 parts by weight of extract

00.0 parts by weight of base

Zinc pyrithione 3.0 parts by weight

Glycerin 1.0 parts by weight

Polyethylene glycol 1.0 part by weight

1.5 parts by weight of tocopherol acetate

0.1 parts by weight of titanium oxide

Cocamidopropyl Betaine 6 parts by weight

4 parts by weight of purified water

As seen above, the earth 7-13 parts by weight of the present invention, 6.0-7.5 parts by weight, boksan 6.0-7.0 parts by weight, 6.8-7.8 parts by weight of hwahwa, 4.7-6.7 parts by weight peony, 3.5-5.5 A weight part, and a cleaning agent including a neck and 3.5 to 5.0 parts by weight can be usefully used as a cleaning composition for improving hair loss and hair growth without a blood pressure increase or a composition for promoting hair.

Claims (8)

7-13 parts by weight of earth, 6.0-7.5 parts by weight of bokbok, 6.0-7.0 parts by weight of hawthorn, 6.8-7.8 parts by weight of cheonhwa, 4.7-6.7 parts by weight of peony, 3.5-5.5 parts by weight of bark skin and 3.5-5.0 parts by weight of neck Cleaning composition for improving hair loss and hair growth without blood pressure increase containing the extract of the herbal compound comprising as an active ingredient.
According to claim 1, wherein the composition is selected from the group consisting of 15 to 19 parts by weight Jeonho, 7.5 to 11.5 parts by weight of confectionery, 6.8 to 7.8 parts by weight of Guernsey sulfur, 3.5 to 5.5 parts by weight of the lieutenant line, 1.8 to 3.8 parts by weight A composition for improving hair loss and hair growth without blood pressure, characterized in that the extract of the herbal compound further comprising any one or more herbal medicines.
According to claim 1, wherein the composition is glycerin 1.5 to 3.5 parts by weight, honey 1.5 to 3.5 parts by weight, potassium carbonate 2 to 4 parts by weight, sodium sulfate 1 to 3 parts by weight, calcium carbonate 1 to 3 parts by weight, magnesium carbonate 1 ~ 2 parts by weight, 0.1 to 0.3 parts by weight of iron oxide, and 0.1 to 0.3 parts by weight of boric acid further comprises any one or more selected from the group consisting of blood pressure increase without hair loss and hair growth cleaning composition.
According to claim 1, wherein the composition is a cleaning composition for improving hair loss and hair growth without blood pressure increase, characterized in that the formulation is made of any one selected from the group consisting of spray, cream, shampoo and soap.
7-13 parts by weight of earth, 6.0-7.5 parts by weight of bokbok, 6.0-7.0 parts by weight of hawthorn, 6.8-7.8 parts by weight of cheonhwa, 4.7-6.7 parts by weight of peony, 3.5-5.5 parts by weight of bark skin and 3.5-5.0 parts by weight of neck Hair loss prevention or hair growth promoting composition comprising an extract of the herbal compound containing as an active ingredient.
According to claim 5, wherein the composition is selected from the group consisting of 15 to 19 parts by weight of Jeonho, 7.5 to 11.5 parts by weight of confectionery, 6.8 to 7.8 parts by weight of Guernsey sulfur, 3.5 to 5.5 parts by weight of the gastric gland, and 1.8 to 3.8 parts by weight of lettuce Hair loss prevention or hair growth promoting composition, characterized in that the extract of the herbal compound comprising any one or more herbal medicines.
According to claim 5, wherein the composition is glycerin 1.5 to 3.5 parts by weight, honey 1.5 to 3.5 parts by weight, potassium carbonate 2 to 4 parts by weight, sodium sulfate 1 to 3 parts by weight, calcium carbonate 1 to 3 parts by weight, magnesium carbonate 1 to A cleaning composition for preventing hair loss or promoting hair growth, further comprising any one or more selected from the group consisting of 2 parts by weight, 0.1 to 0.3 parts by weight of iron oxide, and 0.1 to 0.3 parts by weight of boric acid.
The method of claim 5, wherein the composition is a cleaning composition for preventing hair loss or promoting hair growth, characterized in that the formulation is made of any one selected from the group consisting of spray, cream, shampoo, and soap.

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