KR101060035B1 - Herbal Compositions and Herbal Medicine Pills for Eye Fatigue and Vision Improvement - Google Patents

Herbal Compositions and Herbal Medicine Pills for Eye Fatigue and Vision Improvement Download PDF

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KR101060035B1
KR101060035B1 KR1020090111284A KR20090111284A KR101060035B1 KR 101060035 B1 KR101060035 B1 KR 101060035B1 KR 1020090111284 A KR1020090111284 A KR 1020090111284A KR 20090111284 A KR20090111284 A KR 20090111284A KR 101060035 B1 KR101060035 B1 KR 101060035B1
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herbal
eye fatigue
weight
parts
herbal composition
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KR20110054579A (en
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강홍구
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강홍구
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/80—Scrophulariaceae (Figwort family)
    • A61K36/804—Rehmannia
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8965—Asparagus, e.g. garden asparagus or asparagus fern
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction

Abstract

본 발명은 눈의 피로 완화 및 시력개선효과를 갖는 한약조성물 및 한약 환제를 제공하며 숙지황, 천문동, 지각, 감국, 솔잎, 구기자, 하모려를 포함하는 총7종의 한약재를 함유함으로써 대부분의 근시, 원시, 난시, 눈의 피로등의 증상을 우수하게 개선할 수 있다.The present invention provides a herbal composition and herbal pills having an effect of relieving eye fatigue and improving eyesight, and by containing a total of seven kinds of herbal medicines including Sukjihwang, Astronomical Cultivation, Perception, Gamkook, pine needles, Gugija and Hamori, most of myopia, It can improve symptoms such as hyperopia, astigmatism and eye fatigue.

한약조성물, 근시, 원시, 난시, 눈의 피로, 솔잎 Chinese herbal composition, myopia, hyperopia, astigmatism, eye fatigue, pine needle

Description

눈의 피로 완화 및 시력개선용 한약조성물 및 한약 환제{HERBAL MEDICINE COMPOSITE AND PILL FOR OPHTHALMIC FATIGUE RELIEF AND EYESIGHT RECOVERY}HERBAL MEDICINE COMPOSITE AND PILL FOR OPHTHALMIC FATIGUE RELIEF AND EYESIGHT RECOVERY}

본 발명은 눈의 피로 완화와 시력개선용 한약조성물 및 한약 환제에 관한 것으로 상세하게는 근시, 원시, 난시, 눈의 피로등의 증상을 우수하게 개선할 수 있는 한약조성물 및 한약 환제에 관한 것이다.The present invention relates to herbal compositions and herbal pills for relieving eye fatigue and improving eyesight, and more particularly, to herbal compositions and herbal pills that can improve symptoms such as myopia, hyperopia, astigmatism, and eye fatigue.

최근 우리나라는 산업발달과 생활수준의 향상, 각종 문화시설의 도입으로 인해 장시간 오염된 환경에 노출되고, 과도한 스트레스로 인하여 시력장애를 유발하는 질환이 증가하는 추세다.Recently, Korea has been exposed to polluted environment for a long time due to industrial development, improvement of living standards and introduction of various cultural facilities, and diseases that cause vision disorder due to excessive stress are increasing.

그럼에도 불구하고 시력개선, 눈의 피로 완화 등의 효과가 우수한 한약조성물은 거의 없는 실정이다.Nevertheless, there are few herbal compositions with excellent effects such as improvement of vision and relief of eye fatigue.

본 발명의 목적은 근시, 원시, 난시 및 눈의 피로 증상의 개선에 우수한 한약조성물 및 한약 환제를 제공하는데 있다.SUMMARY OF THE INVENTION An object of the present invention is to provide a herbal composition and a Chinese medicine pill that are excellent for improving symptoms of myopia, hyperopia, astigmatism and eye fatigue.

상기 목적을 달성하기 위하여 본 발명에 따른 눈의 피로 완화 및 시력 개선용 한약조성물은 숙지황 6 내지 8 중량부 천문동 6 내지 8 중량부 지각 3 내지 4 중량부 감국 3 내지 4 중량부 솔잎 1.5 내지 2 중량부 구기자 0.7 내지 1 중량부 하모려 0.7 내지 1 중량부를 포함하여 이루어지는 것을 특징으로 한다.In order to achieve the above object, the herbal composition for relieving eye fatigue and improving eyesight according to the present invention is 6-8 parts by weight of Sukjihwang 6-8 parts by weight Cheonmun-dong 6-8 parts by weight 3-4 parts by weight persimmon 3-4 parts by weight of pine needles 1.5-2 weight Boogija 0.7 to 1 part by weight, characterized in that it comprises 0.7 to 1 part by weight.

또한, 상기 목적을 달성하기 위하여 본 발명에 따른 한약 환제는 상기의 한약조성물을 포함하여 이루어진 것을 특징으로 한다. In addition, the Chinese herbal pill according to the present invention in order to achieve the above object is characterized in that it comprises the herbal composition.

또한, 상기 목적을 달성하기 위하여 본 발명에 따른 한약조성물은 상기의 한약조성물을 열수추출하여 제조되는 열수추출물을 유효성분으로 포함하는 것을 특징으로 한다.In addition, in order to achieve the above object, the herbal composition according to the present invention is characterized in that it comprises a hot water extract prepared by hot water extraction of the herbal composition as an active ingredient.

본 발명에 의하면, 본 발명의 한약조성물을 환제, 정제, 캡슐제, 액제, 건강식품, 건강음료등과 같은 제형으로 제조하여 복용함으로써 눈의 피로 증상, 근시, 원시, 난시 등을 개선할 수 있다.According to the present invention, it is possible to improve eye fatigue symptoms, myopia, hyperopia, astigmatism, etc. by preparing and taking the herbal compositions of the present invention in formulations such as pills, tablets, capsules, liquids, health foods, health drinks, and the like. .

본 발명에 따른 눈의 피로 증상 완화 및 시력 개선용 한약조성물을 이루는 성분들에 대하여 설명한다.It describes the components of the herbal composition for relieving fatigue symptoms and improving eyesight according to the present invention.

숙지황(Rehmanniae Radix Vaporata)은 기억 및 학습능력 증강작용, 혈당을 내리며 순환기 계통에 작용하여 강심 및 이뇨작용을 보인다. 또한 간 기능 보호작용, 향균작용, 자양강장, 혈당강하, 강심, 이뇨, 항히스타민(Antihistamin)효과가 있다.Sukji-hwang (Rehmanniae Radix Vaporata) is a memory and learning ability enhancer, lowering blood sugar and acting on the circulatory system has a strong and diuretic effect. In addition, liver function protection, antibacterial, nourishing tonic, hypoglycemic, cardiac, diuretic, antihistamine (Antihistamin) effect.

천문동(天門冬, Asparagi Radix)은 간암저해효과, 간해독작용, 가래를 삭이는 거담효과를 가지고 있다.Asparagi Radix has the effect of inhibiting liver cancer, liver detoxification, and sputum.

탱자(Poncirus trifoliata)는 운향과의 낙엽관목으로 중국 원산이며 경기도 이남에서 가꾸고 있다. 탱자는 비장과 위에 작용하는데, 탱자나무의 어린 과실을 지실이라 하고 성숙한 과실은 지각이라 하여 비슷한 효능을 지니고 있다. 특히, 지각은 정체된 기와 담, 음식물 등을 잘 통하게 하며 증초 소화기에 작용하여 기능을 원활하게 해주는 작용이 있다. 즉, 기가 정체하여 가슴과 배가 그득하고 부푼 것, 가슴이 답답하고 누르면 아픈 것, 부종, 소화불량, 변비 등을 다스리며, 근래 위하수, 자궁하수, 탈항 등에도 효과가 있는 것으로 밝혀졌다. 또한, 약리실험 결과, 자궁수축 작용, 위장운동 항진 작용, 강심 작용, 이뇨 작용 등이 있다는 보고가 있으며, 항염, 항산화, 항알러지, 항과민 작용 등도 알려져 있다.The Panja (Poncirus trifoliata) is a deciduous shrub to Yunhyang, native to China, and grown in south of Gyeonggi-do. The tanza acts on the spleen and stomach, and the fruit of the tanza is called fruit and the mature fruit is called perception. In particular, the crust through the stagnant flag and bile, food, etc. and acts to facilitate the functioning of the digestive organs has a function to facilitate the function. In other words, the stagnation of the chest and abdomen, swelling and swelling, chest tightness and pressing pain, swelling, indigestion, constipation, such as to control the gastrointestinal sewage, uterine sewage, it has been found to be effective. In addition, as a result of pharmacological experiments, there are reports that there are uterine contraction action, gastrointestinal hyperactivity action, cardiovascular action, diuretic action, and the like, anti-inflammatory, antioxidant, anti-allergic, anti-hypersensitivity and the like.

감국(Chrysanthemum indicun)은 다년생 식물로서 국내에서는 산지에서 많이 자생할 뿐만 아니라 대량으로도 재배되고 있으며, 본초강목에서는 간을 편안하게 다스리고 눈을 맑게 해주며, 열을 내리고 독기를 풀어준다고 기술하고 있다. 또한, 항균 작용과 항바이러스 작용 및 항염증 작용 등 다양한 생리학적 효과가 보고 되 어 있다.Chrysanthemum indicun is a perennial plant that is not only native to mountains but also cultivated in large quantities in Korea. The herbaceous wood describes the liver to be comfortable, to clear the eyes, to reduce heat and to release poison. In addition, various physiological effects such as antimicrobial, antiviral and anti-inflammatory effects have been reported.

솔잎은 소나무의 잎으로서 소나무(Pinus densiflora Seibold et Zuccarini)로부터 채집할 수 있다. 솔잎은 예로부터 한방 또는 인간 요법의 약용이나 건강식품으로 이용되고 있고, 동의보감에 의하면 솔잎은 위장병, 중풍, 고혈압, 신경통, 천식 등에 치료 효과가 있다고 알려져 있다. 솔잎의 이러한 약리작용은 솔잎에 함유되어 있는 정유 성분, 단백질, 비타민A, 비타민C, 비타민K, 비타민 P(루틴), 인, 철분, 효소, 탄닌, 엽록소, 고미성 물질, 플라보노이드 등의 성분에 의해 이루어진다. Pine needles can be collected from pine (Pinus densiflora Seibold et Zuccarini) as the leaves of pine. Pine needles have long been used as a medicinal or health food for herbal or human therapies. According to the consent, pine needles are known to have a therapeutic effect on gastrointestinal diseases, stroke, hypertension, neuralgia, and asthma. The pharmacological action of pine needles is based on the essential oils, proteins, vitamin A, vitamin C, vitamin K, vitamin P (routine), phosphorus, iron, enzymes, tannins, chlorophyll, high-flavor substances and flavonoids contained in pine needles. Is made by

모려(Ostreae testa)는 조개과(Ostridae)에 속하는 굴(Ostrea gigas Thunberg) 의 껍질로 주성분은 80∼95% 탄산칼슘, 인산칼슘 외 마그네슘, 알미늄, 규소 및 산화철로 이루어져 있다. 한방에서 그 귀경은 간(肝) 및 신경(腎經)으로 효능은 간의 양기를 진정시키는 작용이 있어 흉·복부의 동계(動悸) 및 그 밖에 정신불안, 불면, 조광(躁狂)등에 사용되고 있으며, 지산(止酸)작용이 있는 것으로 알려져 있다. 이것을 현대적 의미로 해석하면 단순한 제산제(除酸劑)의 기능 뿐만 아니라 스트레스로 인한 위산분비 억제작용이 있다고 할 수 있다.Ostreae testa is a shell of Ostridae oyster (Ostrea gigas Thunberg), which is composed of 80-95% calcium carbonate, calcium phosphate, magnesium, aluminum, silicon and iron oxide. In oriental medicine, the ear is the liver and nerves, and it has the effect of calming the liver's yang, and it is used for the winter of the chest and abdomen and other mental anxiety, insomnia and dimming. It is known that there is acidic action. If you interpret this in a modern sense, it can be said that not only the function of antacids (除 酸 劑) but also the suppression of gastric acid secretion due to stress.

구기자는 가지과에 속하는 낙엽관목 구기자 나무 (Lycium chinense Mill), 영하구기(Lycium barbarum L.)의 열매로서, 우리나라와 중국 각지에 분포한다. 구기자 나무는 덩굴성 관목으로 개화기는 6 내지 9월이고 결실기는 7 내지 10월이다. 한약재로서 구기자는 여름과 가을에 다 익은 열매를 따서, 꼭지를 때고 서늘한 곳에 두어 열매 껍질에 주름이 질 때까지 말린 후 다시 햇볕에 겉껍질이 딱딱해지고 열매 속이 말랑말랑해질 때까지 말려 사용한다.Goji is a fruit of the deciduous tree, Lycium chinense Mill and Lycium barbarum L., which belongs to the branch family and is distributed throughout Korea and China. The wolfberry tree is a vine shrub, flowering period from June to September and fruiting period from July to October. As a Chinese herb, goji berries pick ripe fruits in summer and autumn, place them in a cool place and dry them until they become wrinkled in the fruit peel, and then dry them until the outer skin becomes hard and soft inside.

예로부터 한약재로 사용되어 온 구기자는 간장과 신장을 보하고 피를 생겨나게 하며 눈을 맑게 해주는 등의 효과가 있다고 알려져 왔다. Goji has been used as a herbal medicine for a long time. It has been known to have effects on the liver, kidneys, blood, and eyes.

본 발명에 따른 한약조성물은 이상의 7종을 포함하여 이루어짐을 특징으로 한다.Herbal compositions according to the invention is characterized in that it comprises more than seven species.

이들 성분을 모두 한약 제조시 사용되는 통상의 건조된 약재형태의 것을 의미한다. 상기 각 성분이 상, 하한의 범위를 벗어날 경우 효과가 미약하거나 없게 된다.All of these ingredients are in the form of conventional dried medicine used in the manufacture of Chinese medicine. If each component is outside the upper and lower limits, the effect is weak or absent.

상기한 조성을 갖는 본 발명의 한약조성물을 통상의 방법에 따라 열수 추출하여 열수 추출물을 얻을 수 있으며, 이 추출물을 동결 건조하여 분말당 건조추출물을 얻을 수도 있다.The herbal composition of the present invention having the composition described above may be subjected to hot water extraction according to a conventional method to obtain a hot water extract, and the extract may be freeze-dried to obtain a dry extract per powder.

이들 추출물을 유효성분으로 포함하여 효과를 얻을 수 있다.It can be obtained by including these extracts as an active ingredient.

열수 추출은 100-250℃ 온도에서 2-3시간 동안 하는 것이 바람직하다.Hot water extraction is preferably carried out at 100-250 ° C. for 2-3 hours.

또한, 상기조성을 갖는 본 발명의 한약조성물을 통상의 방법에 따라 물, 탄소수 1 내지 5의 알코올 또는 알코올 수용액으로 이루어지는 군으로부터 선택된 1종 이상의 용매를 사용하여 추출함으로써 추출액을 얻을 수 있으며 이 추출액 또는 이를 동결건조하여 얻은 분말상 건조추출물을 사용할 수도 있다.In addition, the herbal composition of the present invention having the above composition can be extracted by using one or more solvents selected from the group consisting of water, an alcohol having 1 to 5 carbon atoms or an aqueous solution of alcohol according to a conventional method, and an extract can be obtained or the same. Powdered dry extracts obtained by lyophilization can also be used.

이러한 본 발명의 한약조성물은 상기한 성분을 포함하여 제조되는 것이라면 그 제형에 특별한 제한이 없으며, 예를 들어 환제, 정제, 캡슐제, 액제, 건강식품, 건강음료 등과 같은 제형을 가질 수 있다.The herbal composition of the present invention is not particularly limited as long as it is prepared by including the above components, and may have a formulation such as pills, tablets, capsules, liquids, health foods, health drinks, and the like.

이하, 제조예 및 실시예를 들어 본 발명을 상세히 설명하지만 본 발명이 이를 예로만 한정되는 것은 아니다.Hereinafter, the present invention will be described in detail with reference to Preparation Examples and Examples, but the present invention is not limited thereto.

[제조예 1] 한약조성물Preparation Example 1 Herbal Medicine Composition

1. 원료분말 공정1. Raw material powder process

숙지황 400g 천문동 400gSukji Hwang 400g Cheonmundong 400g

감 국 200g 지 각 200g200 g persimmon 200 g

솔 잎 100g 구기자 50gBrush Leaf 100g Wolfberry 50g

하모려 50g 을 혼합기에 넣고 분쇄하였다.50 g of hamores were put in a mixer and ground.

2. 반죽기에 분쇄된 분말 1400g과 꿀 700g 중량비율로 10분간 반죽하였다.2. The dough was kneaded for 10 minutes at a weight ratio of 1400 g of powder and 700 g of honey.

3. 절단 공정3. cutting process

다져진 반죽 혼합물을 장환기 속에 넣고 압축하여 지름 3mm의 굵기로 12-15cm길이로 절단하였다.The chopped dough mixture was put into a janghwangi, compressed and cut into 12-15 cm lengths with a thickness of 3 mm.

4. 환상제조 공정4. Circular manufacturing process

장환기에서 혼합물을 제환기에 투입하여 10분 정도 작동시켜 약 3mm의 환상으로 제조하였다.The mixture was introduced into the deaerator at the long ringer and operated for about 10 minutes to prepare a ring of about 3 mm.

5. 건조공정5. Drying process

제환기에서 제조된 환을 50℃에서 2시간 동안 건조하여 환에 포함된 수분을 완전히 제거하였다.The ring prepared in the machine was dried at 50 ° C. for 2 hours to completely remove moisture contained in the ring.

6. 포장공정6. Packing process

완성된 환을 50환 단위로 포장하고 멸균처리하였다.The completed ring was packaged in 50 ring units and sterilized.

[제조예 2] 한약조성물Preparation Example 2 Herbal Medicine Composition

정수기물 3.5가 담긴 압력식 약탕기에 제조예 1의 혼합물 1400g을 투입한 후 100-125℃ 온도에서 3시간 동안 열수 추출하여 포장기를 이용하여 120cc단위로 포장하였다.1400 g of the mixture of Preparation Example 1 was added to a pressure bath containing water purifier 3.5, followed by extracting hot water at a temperature of 100-125 ° C. for 3 hours, and packaging the pack in 120 cc units using a packaging machine.

[시험예 1][Test Example 1]

제조예 1 에서 얻어진 환제를 2009년 4월부터 10월까지 본원에 내원한 원시, 안구피로, 비문증을 호소하는 환자 21명에게 아침, 저녁 공복시에 1일 2회 2개월간 복용시켰다.The pill obtained in Production Example 1 was taken from April, October, 2009 to 21 patients with complaints of hyperopia, ocular fatigue, and insomnia for two months, twice daily, on an empty stomach.

Figure 112009070692063-pat00001
Figure 112009070692063-pat00001

[시험예 2][Test Example 2]

제조예 2 에서 얻어진 탕제를 2009년 4월부터 10월까지 본원에 내원한 난시, 근시, 안구피로를 호소하는 환자 13명에게 아침, 저녁 공복시에 1일 2회 2개월간 복용시켰다.The prosthesis obtained in Production Example 2 was administered to 13 patients with astigmatism, myopia and ocular fatigue who visited the present hospital from April to October 2009 twice a day for two months in the morning and evening on an empty stomach.

Figure 112009070692063-pat00002
Figure 112009070692063-pat00002

Claims (3)

눈의 피로 완화 및 시력개선용 한약조성물에 있어서 숙지황 6 내지 8 중량부 천문동 6 내지 8 중량부 지각 3 내지 4 중량부 감국 3 내지 4 중량부 솔잎 1.5 내지 2 중량부 구기자 0.7 내지 1 중량부 하모려 0.7 내지 1 중량부를 포함하여 이루어짐을 특징으로 하는 눈의 피로 완화 및 시력개선용 한약조성물.In Chinese herbal medicine for eye fatigue relief and vision improvement, 6 to 8 parts by weight Cheonmundong 6 to 8 parts by weight Perception 3 to 4 parts by weight Korean soup 3 to 4 parts by weight Pine needles 1.5 to 2 parts by weight Wolfberry 0.7 to 1 parts by weight Herbal composition for relieving eye fatigue and improving eyesight, characterized in that comprises 0.7 to 1 parts by weight. 청구항 1의 한약조성물을 포함하여 이루어진 것을 특징으로 하는 한약 환제.Herbal medicine pill comprising the herbal composition of claim 1. 청구항 1의 한약조성물을 열수 추출하여 제조되는 열수추출물을 유효성분으로 포함하는 눈의 피로 완화 및 시력개선용 한약조성물.Herbal composition for relieving eye fatigue and improving eyesight comprising a hot-water extract prepared by extracting the herbal composition of claim 1 as an active ingredient.
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