KR101022577B1 - 항원성이 감소한 중합체 콘쥬게이트, 이의 제조방법 및용도 - Google Patents

항원성이 감소한 중합체 콘쥬게이트, 이의 제조방법 및용도 Download PDF

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KR101022577B1
KR101022577B1 KR1020057005504A KR20057005504A KR101022577B1 KR 101022577 B1 KR101022577 B1 KR 101022577B1 KR 1020057005504 A KR1020057005504 A KR 1020057005504A KR 20057005504 A KR20057005504 A KR 20057005504A KR 101022577 B1 KR101022577 B1 KR 101022577B1
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conjugate
group
kda
polyalkylene glycol
peg
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KR20050083702A (ko
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알렉사 엘. 마르티네즈
메리 알. 셔만
마크 쥐. 피. 세이퍼
엘. 데이비드 윌리암스
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마운틴 뷰 파마슈티컬즈, 인크.
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    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/34—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from hydroxy compounds or their metallic derivatives
    • A—HUMAN NECESSITIES
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    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/646—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
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    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
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    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
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KR1020057005504A 2002-09-30 2003-09-25 항원성이 감소한 중합체 콘쥬게이트, 이의 제조방법 및용도 Expired - Fee Related KR101022577B1 (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US41442402P 2002-09-30 2002-09-30
US60/414,424 2002-09-30
US10/317,092 US20040062748A1 (en) 2002-09-30 2002-12-12 Polymer conjugates with decreased antigenicity, methods of preparation and uses thereof
US10/317,092 2002-12-12

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KR20050083702A KR20050083702A (ko) 2005-08-26
KR101022577B1 true KR101022577B1 (ko) 2011-03-16

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KR1020057005504A Expired - Fee Related KR101022577B1 (ko) 2002-09-30 2003-09-25 항원성이 감소한 중합체 콘쥬게이트, 이의 제조방법 및용도

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US (1) US20040062748A1 (https=)
EP (2) EP2535347A1 (https=)
JP (2) JP5366352B2 (https=)
KR (1) KR101022577B1 (https=)
CN (2) CN1997661B (https=)
AU (1) AU2003275176B8 (https=)
BR (1) BRPI0314831B8 (https=)
CA (2) CA2500389C (https=)
CR (1) CR7776A (https=)
DK (1) DK1572728T3 (https=)
EA (1) EA009122B1 (https=)
EC (1) ECSP055717A (https=)
ES (1) ES2504165T3 (https=)
GE (1) GEP20074016B (https=)
HR (1) HRP20050353B1 (https=)
IL (1) IL167723A (https=)
IS (1) IS2944B (https=)
MA (1) MA27521A1 (https=)
MX (1) MXPA05003394A (https=)
NO (1) NO20052089L (https=)
NZ (1) NZ539133A (https=)
PT (1) PT1572728E (https=)
RS (1) RS20050263A (https=)
TW (1) TWI362942B (https=)
WO (1) WO2004030617A2 (https=)

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