KR100915899B1 - Granules for treating teeth/implant and method of manufacturing and using same - Google Patents

Abstract

A sintering material for treating tooth and implant, a method for manufacturing the same, and a method of use are provided, in which the sintering material is adsorbed securely to the bone defect region of the tooth and restores the defect region rapidly. A manufacturing method of the sintering material for treating the tooth and implant comprises: a first step(S10) for stirring and mixing the treatment material consisting of the solid powder of one kind and dispersing medium of the third distilled water selected from the calcium phosphate based compound group with bead of ceramic powder and milling and dispersing for 1-48 hours; a second step(S20) that the organic matter additive is selectively added and becomes slurry while progressing the milling dispersion of the first step; a third step(S30) for forming the calcium phosphate group in a granule shape to dry the capsulated slurry; and a fourth stage(S40) for selectively classifying the particle size.

Description

Sintered material for tooth and implant treatment and its manufacturing method and method {granules for treating teeth / implant and method of manufacturing and using same}

The present invention relates to a sintered material for the treatment of teeth and implants, and to a method of manufacturing and using the same, more specifically, using a calcium phosphate-based compound and rapidly adsorbed to a bone defect site of a tooth using a pneumatic injector. The present invention relates to a sintered material for treating teeth and implants, and a method of manufacturing and using the same.

Generally, the sintered material for treating teeth and implants refers to powders used for teeth and implant treatment operations such as alleviation of hypersensitivity of teeth, removal of inflammation around the implant and removal of inflammatory granulation tissue around the implant.

Here, the perceptual hypersensitivity may also be referred to as dentin hypersensitivity, hypersensitivity, or syringa, and may be caused by exposing the cervical portions by exposing the gums, or may be generated after erroneous brushing or periodontal disease itself, scaling or periodontal treatment.

In addition, the cervical region may be thinly chalky (20-50 micrometers) or completely absent. In the chalky region, the dentin tubule is located very close to the tooth surface from the pulp. Hypersensitivity may occur.

Moreover, the hypersensitivity hypersensitivity is caused by the rapid movement of the liquid inside the ivory tubule by a certain stimulus (physical, chemical, thermal), which also stimulates the nerve endings of the pulp. It also occurs when the root is exposed and the dentin of the root is exposed.

In addition, the peri-implantitis refers to an inflammatory response with loss of supporting bone tissue in the surrounding tissue of the implant in which microorganisms have the same pattern as that of the tooth, and has characteristics similar to those of chronic periodontitis in adults. It is caused by the destruction caused by bacteria in surrounding tissues, and as the site around the implant collapses, a complex microbial group is formed and inflammation occurs.

In addition, the inflammatory granulation tissue around the implant is an inflammation occurring around the granulation tissue, which is a histologically rich capillary-rich new connective tissue in order to separate and remove necrotic tissue, to fill a defect due to a wound, or to exclude foreign substances. It must be removed because it is infected.

1 is a scanning electron micrograph of sodium bicarbonate granules used as a conventional sintering material for teeth and implant treatment.

As shown in Figure 1, the conventional sintered material for treating teeth and implants is a powder of sodium bicarbonate (NaHCO ₃ ).

However, the granules of sodium hydrogen carbonate are non-uniform in form of white crystal lumps or crystalline powders, so that the contact surface area between the particles increases and dissolution occurs when moisture is adsorbed, so that the particles are easily aggregated, so that the aggregated particles As a result of frequent clogging when gas passes through the pneumatic injector nozzle, the remaining surrounding tissues exhibit foreign body reactions when they are removed during calculus removal or inflammation around the implant. There was a problem that prevents the formation of new bone.

In addition, sodium bicarbonate has a problem that can not be used in patients requiring attention to salt intake because sodium is composed of the main component.

The present invention is prepared using a calcium phosphate-based compound to solve the above problems and has the function of firmly adsorbed to the bone defects of the teeth using a pneumatic sprayer to quickly repair and to remove the dental implant peripheral salts It is an object of the present invention to provide a sintered material for treating teeth and implants, and a method of manufacturing and using the same.

In order to solve the above problems, hydroxyapatite, fluorapatite, alpha-tricalcium phosphate, alpa-tricalcium phosphate, Using one selected from the group of calcium phosphate compounds including beta-tricalcium phosphate, calcium metaphosphate, brushite and monetite as solid solution, 3 Slurry prepared by performing a miller process in which organic additives are selectively added while finely dispersing for 1 hour or more and 48 hours or less using a bead of ceramic material with tea distilled water as a dispersion medium ( slurry), the pumping speed is 10 ~ 50 ml / min, the inlet temperature of the treatment space (inlet) 150 ~ 220 ℃, the outlet on the treatment space Spray drying is performed at an outlet range of 60 to 150 ° C. and a spray nozzle rotational speed (RPM) within the processing space of 5000 to 12000 rpm, wherein the inlet temperature is greater than or equal to 30 ° C. between the outlet temperature. Spherical granules obtained by drying and removing the residual moisture in the range of 50 to 150 ℃ and 1 to 24 hours, respectively, by heat treatment and sieving. It provides a sintered material for treating teeth and implants consisting of granules.

Here, the spray drying treatment is the pumping speed of the slurry is 10 ~ 50 ml / min, the inlet temperature of the treatment space (inlet) 150 ~ 220 ℃, the outlet temperature of the treatment space (outlet) 60 ~ 150 ℃, the Spray nozzle rotational speed (RPM) inside the processing space is preferably 5000 ~ 12000 rpm, drying temperature and time to remove the residual moisture in the range of 50 ~ 150 ℃ and 1 ~ 24 hours, respectively. In addition, the organic additive is composed of PVA (polyvinyl alcohol), MC (methyle cellulose), CMC (carboxy methyle cellulose), acrylic emulsion (emulsion) and wax-based emulsions based on 100% by weight of the solid solution 1 ~ 30% by weight of the binder, PEG (polyethylene glycol), glycerin (glycerin), consisting of one of DBP (dibutylphthalate) and propylene glycol (propylene glycol) of 0.1 to 50 based on 100% by weight of the binder Plasticizer in the range of weight%, polycarboxylic acid-based, naphthalenesulfonic acid formal (condensate), phosphate (phosphate), phosphate complexes and amines of one of the above It is preferably made of a dispersant in the range of 0.1 to 10% based on 100% by weight of the powder, and an antifoaming agent of silicon and non-silicone based on the range of 0.1 to 10% based on 100% by weight of the solid solution.

On the other hand, the step of filling the dental polishing machine with the sintering material for treating the teeth and implant of claim 1; And using the dental polishing machine to spray the tooth and implant treatment sintering material at the same time as pneumatic and hydraulic pressure to the treatment target tooth and the implant site.

On the other hand, in order to manufacture a sintered material for the treatment of teeth and implants used for adsorption and foreign matter removal by spraying by pneumatic and hydraulic pressure, a treatment material consisting of a dispersion of a solid solution and tertiary distilled water selected from the group of calcium phosphate compounds A first step of finely pulverizing and dispersing for 1 hour to 48 hours by stirring and mixing the beads of the ceramic powder; A second step in which the organic material additive is selectively added and slurried while the fine powder dispersion of the first step is performed; In order for the slurry prepared in the second step to be atomized and spray-dried, the pumping speed of the slurry is 10 to 50 ml / min, the inlet temperature of the processing space is 150 to 220 ° C, and the outlet temperature of the processing space. (outlet) spray drying treatment in the range of 60 ~ 150 ℃, spray nozzle rotational speed (RPM) in the processing space of 5000 ~ 12000 rpm, wherein the inlet temperature is the difference between the outlet temperature of more than 30 ℃ A third step of maintaining the drying temperature and time to remove residual moisture by spherical drying in the range of 50 to 150 ° C. and 1 to 24 hours, respectively, and sphering to dense calcium phosphate granules having an average particle diameter of 100 μm or less; And implanting the spherical granules prepared in the third step into an electric furnace, heat treating at a temperature of 700 to 1100 ° C., densifying them, and then selectively classifying the particle sizes through the sieving. Provided is a method for producing a sintered material.

First, in the sintered material for treating teeth and implants of the present invention, the granules prepared using the calcium phosphate-based compound are provided in the form of dense spherical particles through the process of pulverizing dispersion, spray drying and heat treatment. The contact area of can be minimized. In addition, its excellent fluidity prevents nozzle clogging during pneumatic spray polishing, and its high density prevents agglomeration due to moisture adsorption. This can be significantly improved.

Second, the sintered material for treating teeth and implants of the present invention can obtain dense spherical granules by spray-drying treatment by limiting the inlet temperature, the outlet temperature, the spray nozzle rotation speed, and the temperature and time of removing residual moisture to a certain range. .

Third, the sintered material for treating teeth and implants of the present invention is mixed with organic additives of a binder, a plasticizer, a dispersant and an antifoaming agent in the process of pulverizing dispersion, so that a stable slurry is prepared and has a suitable function for dental use. It provides good conditions for making granules which can have a significant improvement in yield.

Fourth, the manufacturing method according to the present invention is manufactured by dividing the tooth particle and the implant for a substantially average particle size of 35 μm and an average particle size of 60 μm, thereby reducing the perceptual hypersensitivity by varying the spray strength and surrounding the tartar, implant It can be conveniently used because it is used in parallel to remove inflammatory tissue and inflammatory granulation tissue.

Fifth, the sintered material for treating teeth and implants of the present invention is bioactive and has a dense spherical shape of a biocompatible non-toxic calcium phosphate compound, so that the injection strength is different from that of sodium hydrogen carbonate powder used only for removing foreign substances. By adjusting, there is an advantage that can be performed in parallel with the adsorption work for bone restoration and the removal of foreign substances such as dental plaque and inflammatory tissue around the implant.

Hereinafter, a sintered material for treating teeth and implants according to a preferred embodiment of the present invention will be described in detail.

Sintered material for treating teeth and implants according to a preferred embodiment of the present invention is hydroxyapatite (Ca ₁₀ (PO ₄ ) ₆ (OH) ₂ ), fluorapatite, (Ca ₁₀ (PO ₄ ) ₆ F ₂ )), alpha-tricalcium phosphate (α-Ca ₃ (PO ₄ ) ₂ ), beta-tricalcium phosphate (β-Ca ₃ (PO ₄ ) ₂ ), calcium meta Employ one selected from the group of calcium phosphate compounds, including phosphate (calcium metaphosphate, [Ca (PO ₃ ) ₂ ] n), brushite, (CaHPO 2H ₂ O)) and monnetite, CaHPO ₄ As a powder, a miller process in which organic additives are selectively added while finely dispersing for 1 to 48 hours using ceramic beads with tertiary distilled water as a dispersion medium. Slurry prepared by spraying in a high temperature dry medium Division by being processed spray drying (spray drying) consists of a spherical granule.

The granules prepared as described above are completely removed by the heat treatment, and the organic additives are regenerated into fine granules. In addition, by selectively sifting the particle size through the sieve to use the granule of the desired size.

Here, the calcium phosphate system can be directly applied to the body due to its biocompatibility and non-toxicity, in particular, it has excellent biocompatibility-inducing ability and chemically similar characteristics to hard tissues such as teeth. When adsorbed to the bone defect site of the tooth, it shows strong binding with the hard tissue.

In addition, the calcium phosphate-based compound group can be rapidly restored because the bioabsorbable calcium phosphate-based compound can act as a growth factor for supplying the mineral component of the new bone when the new bone is generated by reacting with osteoblasts. There is an advantage.

Furthermore, the apparatus for performing the miller process includes attrition miller, bead miller, and ball milling, which are pulverized media (beads). ), The solid solution in the treatment material in which the solid solution is mixed with tertiary distilled water is finely ground and dispersed in distilled water as the dispersion medium.

To this end, it is preferable to use a powder having a particle diameter of 0.1 mm or more and 10 mm or less as an alumina material or a zirconia material as the ceramic powder.

Here, if the particle diameter of the beads is less than 0.1 mm, the separation of the grinding media is not easy, and if the particle diameter of the beads exceeds 10 mm, the porosity between the grinding media becomes large, it is difficult to finely grind to the sub-micron level.

In addition, the use of the distilled water does not contain impurities in the solid solution and the suspension of the distilled water.

Moreover, the solid solution refers to the concentration of the calcium phosphate compound in the dispersion medium, where the weight percentage of the calcium phosphate compound is 100% by weight of the mixed solution of the distilled water and the calcium phosphate compound.

Here, the weight ratio of the solid solution and the dispersion medium is selectively used in consideration of the water content of the slurry for smoothly performing the spray drying is 50 to 90%. For example, if the suspension of the solid solution and the dispersion medium is 100% by weight, the solid solution has 50% by weight and the dispersion medium has 50% by weight, the solid solution has 30% by weight and the dispersion medium has 70% by weight. will be.

That is, the solid solution is atomized to a substantially submicron level by stirring the processing material with the beads through the Miller process and pulverizing the solid particles in the dispersion medium in the shearing action by rotation to disperse the dispersion medium. Particles can be obtained.

In addition, the spray drying method for performing the spray drying process is a method for producing granules, a slurry is prepared by mixing the organic material additives described later in the processing material to be pulverized and the slurry is converted into a droplet state during hot air When it is sprayed and dried using a spray dryer to prepare a granule.

That is, the spray drying method makes the treated material of the liquid consisting of a solid solution of calcium phosphate-based compound and water dispersion medium into fine droplets such as fog to increase the surface area of the treated material and blow hot air of 150 ° C or higher into the processing space to By supplying the heat required for water evaporation, it is dried in the shape of a fine spherical granule in a state containing air in an instant.

Here, when the calcium phosphate-based granules spray a slurry containing a calcium phosphate-based compound to form droplets, the droplets have a spherical shape by surface tension, and the sprayed droplets are dried by a method such as hot air drying. As a result, spherical particles are formed. At this time, the setting conditions of the spray dryer for the spray drying treatment is an important factor for determining the particle shape of the granules, which will be described later.

On the other hand, the spray drying treatment is the pumping speed of the slurry is 10 ~ 50 ml / min, the inlet temperature of the treatment space is 150 ~ 220 ℃, the outlet temperature of the treatment space is 60 ~ 150 ℃, the spray nozzle inside the treatment space Rotational speed (RPM) is 5000 ~ 12000 rpm, the drying temperature and time to remove the residual moisture is preferably made in the range of 50 ~ 150 ℃ and 1 ~ 24 hours, respectively.

Here, the spray dryer to be spray-dried is provided with a rotary atomizer (rotary atomizer) to atomize around the disk by centrifugal force when the droplet is supplied to the center of the disk to rotate at high speed.

Of course, the atomizer may also be a pressure nozzle atomizer or a two fluid atomizer.

In addition, the setting conditions of the spray dryer for the spray drying treatment described above is a spherical shape of granules having a particle diameter of 1 or more and 100 micrometers (μm) suitable as a sintering material for treating teeth and implants. To get it. More preferably, the tooth is prepared to have a particle size of 20 to 45 micrometers, and the implant is made to have a particle size of 45 to 75 micrometers, which is related to the rotational speed of the spray nozzle.

In addition, the pumping speed of the slurry is related to the particle size and moisture content of the granules by adjusting the supply amount of the slurry. Therefore, it is advantageous to produce granules having a particle diameter of the granules having a particle size of 1 micrometer or more and 100 micrometers or less in the range of 10 to 50 ml / min.

Moreover, the treatment space refers to a space where spray drying occurs, and the inlet temperature and the outlet temperature are mainly related to the water content of the granules, and also to the apparent density of the granules.

Here, it is preferable that the inlet temperature is 150 ~ 220 ℃, the outlet temperature is 60 ~ 150 ℃, when the inlet temperature exceeds 220 ℃, the slurry droplets immediately after spraying is rapidly dried to solidify the surface as the granules expand Because of the increased assembly, it is not suitable as a sintering material for treating teeth and implants. In addition, since the inlet temperature and the outlet temperature are small, the difference in moisture content of the granules increases, so it is preferable to have a difference of at least 30 ° C or more.

And, the spray nozzle rotational speed (RPM) in the treatment space is 5000 ~ 12000 rpm plays a crucial role in the spherical particles of the sintering material for treating teeth and implants.

In addition, the drying temperature and time to remove the residual moisture in the range of 50 ~ 150 ℃ and 1 ~ 24 hours, respectively, the granules have a particle size, particle size distribution suitable for the sintering material for teeth and implant treatment.

That is, it was found experimentally that the spherical particles are formed under the operating conditions of the spray dryer, and in particular, the size of the sprayed particles is determined by increasing or decreasing the rotational force due to the spray nozzle rotation speed, Granules with spherical particles were formed by spraying the slurry while rotating within the conditions.

Through this, the sintered material for treating teeth and implants of the present invention can obtain spherical granules by spray-drying treatment to limit the inlet temperature, the outlet temperature, the spray nozzle rotational speed, and the temperature and time of residual moisture removal to a certain range.

In addition, by heat-treating the granules formed after the spray drying treatment using a gas atmosphere (nitrogen or argon) electric furnace or a general electric furnace within a range where phase transition does not occur, various organic substances used in forming the granules are removed, and are manufactured in a more compact sphere. Used as a sintering material for dental and implant treatment. Classification of the granule size to suit the function is selectively classified by sifting.

In general, the sintered material for treating teeth and implants may be deficient due to scaling, periodontitis, gingival contraction, tooth shaking, etc., which forms the surface of the tooth, such that the dentin tubule of the inner dentin is exposed to the outside, causing hypersensitivity, etc. It is used to fill fine pores.

In this case, the sintered material for treating teeth and implants is manufactured in a dense spherical granular form with good fluidity in order to minimize nozzle clogging when ejected from a pneumatic injector, and is firmly adsorbed on the exposed ivory tubules to produce a calcium phosphate compound. The sintered material acts as a new bone-induced growth factor and has a function of quickly repairing a bone defect site.

Accordingly, the sintered material for treating teeth and implants of the present invention is provided with a spherical shape of granules prepared using calcium phosphate-based compounds through a process of fine grinding and spray drying, thereby improving contact area between particles compared to the conventional sintered material. Minimized. In addition, due to its excellent fluidity, nozzle clogging was minimized during pneumatic spray polishing, and its high density prevented agglomeration by moisture adsorption. This can be improved.

On the other hand, the organic additive is composed of PVA (polyvinyl alcohol), MC (methyle cellulose), CMC (carboxy methyle cellulose), acrylic emulsion (emulsion) and wax-based emulsion, but the solid solution of the calcium phosphate compound 100 weight It is composed of a binder in the range of 1 to 30% by weight based on%, polyethylene glycol (PEG), glycerin (glycerin), dibutylphthalate (DBP) and propylene glycol (propylene glycol) based on 100% by weight of the binder Plasticizer in the range of 0.1 to 50% by weight, polycarboxylic acid (poly carboxylic acid-based), naphthalenesulfonic acid (formalin) condensation system (phosphate), phosphate (phosphate), phosphate complex and amine Comprising a dispersant in the range of 0.1 to 10% based on 100% by weight of the solid solution of the calcium phosphate compound, and a silicone and non-silicone antifoaming agent in the range of 0.1 to 10% based on 100% by weight of the solid solution Yirueojim than is desirable.

Here, the above-mentioned organic substance additive is added in order to give the function required for granules manufactured from the calcium phosphate compound.

In addition, the binder determines the strength of the sintered material for treating teeth and implants to be granulated. The binder of the above-mentioned kind is effective even with a small amount, and it does not react with the beads of the ceramic powder, can be dissolved in water or a solvent, and can be added as an emulsion, and is completely contained at a relatively low temperature in an oxidizing and non-oxidizing atmosphere. Decomposition and volatilization, the ash content after decomposition and volatilization is 0, and even if slightly left, it does not contain alkali (Na, K) or heavy metals (Fe, Ni, Co, Cr) components, and the decomposition gas is toxic, strong acid, strong alkali It is not sensitive to moisture and is therefore preferred as a binder.

Here, the binder is in the range of 1 to 30% by weight based on 100% by weight of the solid solution of the calcium phosphate-based compound, when the binder is less than 1% by weight because the strength of the sintering material for treating teeth and implants is lowered It cannot function as a removal material for removing tartar and the like, and when the binder exceeds 30% by weight, the granules become too hard and the adsorption power as a bone marrow restoration decreases.

Furthermore, plasticizers of the kind described above are added to the binder with a property of causing plastic deformation with a small force, thereby lowering the glass transition temperature (Tg) of the binder and softening it to facilitate molding.

Here, the plasticizer is made in the range of 0.1 to 50% by weight based on 100% by weight of the binder, if the plasticizer is less than 0.1% by weight is not easy to mold at high temperatures, the yield is reduced, the plasticizer is 50% by weight If exceeded, the strength is lowered, so it is not suitable for bone marrow restoration.

In addition, the dispersant causes the solid solution to be pulverized so that particles having a diameter of several micrometers are dispersed to form a slurry. Dispersants of the kind described above are used to maintain the stability of the slurry. When the shaped body is calcined, the dispersant does not remain in the granules and is smoothly removed without decomposition or combustion of the dispersant.

Here, the dispersing agent is in the range of 0.1 to 10% based on 100% by weight of the solid solution of the calcium phosphate-based compound, it is difficult to obtain a homogeneous sintered material because the dispersing efficiency is lowered when the dispersing agent is less than 0.1% by weight When the dispersant exceeds 10% by weight, the stability of the slurry is lowered, so that the yield of the sintered material is lowered.

In addition, the antifoaming agent serves to prevent the foaming of the sintered material, it is preferably made of 0.1 to 10% range based on 100% by weight of the solid solution of the calcium phosphate compound.

Therefore, the sintered material for treating teeth and implants of the present invention is mixed with organic additives of a binder, a plasticizer, a dispersant, and an antifoaming agent in the process of pulverizing dispersion, so that a stable slurry is prepared and has a function suitable for dental use. The yield can be significantly improved.

2 is a scanning electron micrograph of a sintered material for treating teeth and implants according to a preferred embodiment of the present invention.

This is a sintered material for treating teeth and implants prepared using beta-tricalcium phosphate (β-Ca ₃ (PO ₄ ) ₂ ) in the calcium phosphate compound group according to an embodiment of the present invention. Microstructure. The component has at least 98% by weight of the beta-tricalcium phosphate based on the total weight, and the other contains moisture. The average particle size is 35 micrometers (20-45 micrometers) in size for use in the tooth area or 60 micrometers (45-75 micrometers) for use in tissues around the implant.

Here, it can be seen that the whole particles are uniformly distributed and formed in a spherical shape.

FIG. 3 is a scanning electron microscope (SEM) photograph showing before and after treatment of the sintered material for treating teeth and implants according to a preferred embodiment of the present invention to exposed ivory tubules of the teeth.

First, when the enamel is deficient between the gum and the dentin of the lower enamel, the dentin tube is exposed to the inner side of the chalk, and the hypersensitivity is indicated. To relieve the hypersensitivity and to restore the bone marrow, the cow for treating teeth and implants according to the present invention. Payment is used.

As shown in Figure 3, before the sintering material for treatment of teeth and implants of the present invention (before), the dentinal tubule 31 is exposed to cause the tooth hypersensitivity.

In addition, after the sintered material of the present invention (after), the dentinal tubule 31 is a white portion that is covered by the sintered material is firmly adsorbed to the dentinal tubule, indicating that the hypersensitivity is alleviated.

Here, it can be seen that the sintered material of the present invention is tightly adsorbed to the ivory tubule 31 without any gap.

Figure 4 is a scanning electron micrograph showing before and after removing the sintered material for treating teeth and implants according to a preferred embodiment of the present invention around the implant.

As shown in Figure 4, the sintered material of the present invention appears as a rough surface to the surrounding tissue with inflammation that the surface of the tissue is roughly formed before the treated tissue around the implant (before).

In addition, after the sintered material of the present invention removes the inflammatory tissue around the implant, the surface of the tissue is smoother and appears evenly distributed. Moreover, the sintered material of the present invention remains on the surface around the implant and acts as a growth factor.

Here, it can be seen that the sintered material of the present invention has an excellent effect on removing inflammation around the implant.

5 is a graph showing the results of X-ray diffraction analysis of the sintered material for treating teeth and implants and the conventional β-TCP according to Examples and Comparative Examples of the present invention.

Here, A is a diffraction pattern of the sintered material for teeth and implant treatment prepared by the manufacturing method according to the embodiment of the present invention using β-TCP, B is a conventional diffraction pattern of β-TCP. From the intensity of the diffraction peaks in the X-ray diffraction pattern, the sintered material for treating teeth and implants of the present invention is exactly in line with the international standard based on β-TCP and the impurities are not detected. Can be.

Hereinafter, a method of using the sintered material for treating teeth and implants according to a preferred embodiment of the present invention will be described in detail.

Method of using a sintered material for treating teeth and implants according to a preferred embodiment of the present invention comprises the steps of filling the dental polishing machine with a sintered material for treating teeth and implants; And simultaneously spraying the sintered material for treating the teeth and the implant with hydraulic and pneumatic pressure on the target tooth region using the dental polishing machine.

Here, the dental polishing machine is an air polisher (air polisher) is used, the sintering material for the treatment of teeth and implants is filled therein and the internal filling is injected by air pressure through a nozzle, wherein the water pressure from the water supply unit and It is a device that functions while simultaneously spraying at the nozzle end.

Therefore, the dental grinder is introduced into the tooth area to be treated by the patient, and the sintered material for dental and implant treatment is sprayed by pneumatic and hydraulic pressure to perform treatment.

Through this, by controlling the intensity of the injection, in case of teeth, it can be used to alleviate perceptual hypersensitivity or to remove calculus, gliding of the root, and in the case of implants, inflammation or inflammatory granulation tissue around the implant can be removed.

Hereinafter, a method of manufacturing a sintered material for treating teeth and implants according to a preferred embodiment of the present invention will be described in detail.

Figure 6 is a flow chart showing a method of manufacturing a sintered material for treating teeth and implants according to a preferred embodiment of the present invention.

As shown in Figure 6, the method for producing a sintered material for treating teeth and implants according to a preferred embodiment of the present invention is a ceramic powder comprising a treatment material consisting of a dispersion medium of one solid solution and tertiary distilled water selected from the group of calcium phosphate compounds A first step (S10) of pulverizing and dispersing for 1 hour or more and 48 hours or less by stirring and mixing with a bead of; A second step (S20) in which the organic material additive is selectively added and slurried while the fine powder dispersion of the first step (S10) is performed; A third step (S30) in which the slurry prepared in the second step (S20) is atomized so as to be manufactured into spherical calcium phosphate-based granules having an average particle diameter of 1 to 100 μm; And the spherical granules prepared in the third step is put into an electric furnace and heat treated at a temperature condition of 700 ~ 1100 ℃ and densified and then comprises a fourth step (S40) to selectively classify the particle size through a sieve.

Therefore, the slurry having the particles of the calcium phosphate compound in the submicron state is made into granules having spherical particles since they are atomized by the spray dryer and sprayed and hot-air-dried instantly. In addition, the granulated powder is thermally treated in a nitrogen or argon atmosphere electric furnace or a general electric furnace in a temperature range of 700 ° C. to 1100 ° C. within a range in which phase transition does not occur, thereby producing a final product.

Here, the calcium phosphate-based granules may be used within the range of the above-described conditions for the organic additives made of the above-described binder, plasticizer, dispersant, and antifoaming agent in order to prepare the strength, size, shape, etc. of the sintered material for treating teeth and implants. Will be added.

In addition, when the temperature condition of the heat treatment is less than 700 ℃ the heating temperature is insufficient to remove the organic material is not smooth, the density of the granule itself is lowered and the porosity is increased. When the temperature condition exceeds 1100 ° C, the β-TCP phase has a high probability of phase transition to HAp, and due to such phase transition, cracks may occur and porosity may increase.

Therefore, the manufacturing method according to the present invention is manufactured by dividing the tooth particles and implants with an average particle size of 35 μm and an average particle size of 60 μm substantially, thereby reducing the perceptual hypersensitivity by varying the spray strength and varying the tartar, fixture, It can be conveniently used because it is used in parallel to remove surrounding inflammatory tissue and inflammatory granulation tissue.

In addition, the sintered material for treating teeth and implants of the present invention has a dense spherical shape of calcium phosphate-based compound, and unlike the conventional sodium hydrogen carbonate powder used only for removing foreign substances, it adjusts the spraying strength for adsorption work and bone repair. There is an advantage that can be performed in parallel with the removal of foreign matter, such as dental plaque and inflammatory tissue around the implant.

As described above, the sintered material for treating teeth and implants according to the preferred embodiment of the present invention is not limited to each of the above-described embodiments, and the present invention belongs to the present invention without departing from the scope of the claims of the present invention. Modifications may be made by those skilled in the art and such modifications are within the scope of the present invention.

1 is a scanning electron micrograph of sodium bicarbonate granules used as a sintering material for conventional teeth and implant treatment.

2 is a scanning electron micrograph of a sintered material for treating teeth and implants according to a preferred embodiment of the present invention.

FIG. 3 is a scanning electron micrograph showing before and after treatment of a sintered material for treating teeth and implants according to a preferred embodiment of the present invention to exposed ivory tubules of the teeth.

Figure 4 is a scanning electron micrograph showing before and after removing the sintered material for treating teeth and implants according to a preferred embodiment of the present invention around the implant.

5 is a graph showing the results of X-ray diffraction analysis of the sintered material for treating teeth and implants and the conventional β-TCP according to Examples and Comparative Examples of the present invention.

Figure 6 is a flow chart showing a method of manufacturing a sintered material for treating teeth and implants according to a preferred embodiment of the present invention.

Claims (5)

Pneumatic and hydraulic pressure to be used for adsorption and foreign matter removal, Hydroxyapatite, fluorapatite, alpha-tricalcium phosphate, beta-tricalcium phosphate, calcium metaphosphate, brushite And one selected from the group of calcium phosphate compounds including monetite as a solid solution, Slurry prepared by performing a miller process in which organic additives are selectively added while performing fine grinding dispersion using a bead of ceramic material with tertiary distilled water as a dispersion medium for 1 to 48 hours. (slurry), Pumping speed 10 ~ 50 ml / min, inlet temperature of the treatment space (inlet) 150 ~ 220 ℃, outlet temperature (outlet) of the treatment space is 60 ~ 150 ℃, spray nozzle rotation speed (RPM) inside the treatment space ) Spray drying in the range of 5000 ~ 12000 rpm, the inlet temperature maintains the difference between the outlet temperature of more than 30 ℃, the drying temperature and time to remove residual moisture 50 ~ 150 ℃ and 1 A sintered material for treating teeth and implants comprising spherical granules having a mean particle size of 100 μm or less through heat treatment and sieving through spherical granules obtained by drying in a range of ˜24 hours. delete The method of claim 1, The organic additive PVA (polyvinyl alcohol), MC (methyle cellulose), CMC (carboxy methyle cellulose), acrylic emulsion (emulsion) and wax-based emulsion of one of the range of 1 to 30% by weight based on 100% by weight of the solid solution With binders, Plasticizer of the range of 0.1 to 50% by weight based on 100% by weight of the polyethylene glycol (PEG), glycerin (glycerin), DBP (dibutylphthalate) and propylene glycol (propylene glycol), based on 100% by weight of the binder, Polycarboxylic acid-based, naphthalenesulfonic acid (formalin) condensation system (phosphate), phosphate (phosphate), phosphate complex and amine-based one of the solid solution 100% by weight based on Sintering material for dental and implant treatment, characterized in that comprises a dispersant in the range of 0.1 to 10%, and silicone and non-silicone antifoaming agent in the range of 0.1 to 10% based on 100% by weight of the solid solution. Filling the sintered material for treating teeth and implants of claim 1 in a dental grinder; And Method for using a sintering material for dental and implant treatment comprising the step of simultaneously spraying the tooth and implant treatment sintering material to the treatment target tooth and implant portion by pneumatic and hydraulic pressure using the dental polishing machine. In order to manufacture a sintered material for the treatment of teeth and implants used for adsorption and foreign matter removal by spraying by pneumatic and hydraulic pressure, A first step of pulverizing and dispersing for 1 hour to 48 hours by stirring and mixing a treatment material comprising a solid solution selected from a calcium phosphate compound group and a dispersion medium of tertiary distilled water with beads of ceramic powder; A second step in which the organic material additive is selectively added and slurried while the fine powder dispersion of the first step is performed; In order for the slurry prepared in the second step to be atomized and spray-dried, the pumping speed of the slurry is 10 to 50 ml / min, the inlet temperature of the processing space is 150 to 220 ° C, and the outlet temperature of the processing space. (outlet) spray drying treatment in the range of 60 ~ 150 ℃, spray nozzle rotational speed (RPM) in the processing space of 5000 ~ 12000 rpm, wherein the inlet temperature is the difference between the outlet temperature of more than 30 ℃ A third step of maintaining the drying temperature and time to remove residual moisture by spherical drying in the range of 50 to 150 ° C. and 1 to 24 hours, respectively, and sphering to dense calcium phosphate granules having an average particle diameter of 100 μm or less; And Injecting the spherical granules prepared in the third step into an electric furnace for heat treatment at a temperature of 700 ~ 1100 ℃ densified and then selectively classify the particle size through a sieve for the tooth and implant treatment Method for producing sintered material.

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