KR100896326B1 - A process for preparing granules and pills of ginseng extracts containging high concentration of ginseng - Google Patents

Abstract

The present invention relates to a method for producing ginseng extract granules and pills containing a high concentration of ginseng components, while maintaining the ginsenoside component, which is an active ingredient contained in the high viscosity ginseng extract concentrate before processing, to prevent moisture absorption by long-term storage and It relates to a method for preparing ginseng granules and pills that are easy to ingest.

Ginseng Extract, Extract Granule, Ginseng Pill, Fluidized Bed Process

Description

Ginseng Extract Granules and Pills Containing High Concentration of Ginseng Ingredients {A PROCESS FOR PREPARING GRANULES AND PILLS OF GINSENG EXTRACTS CONTAINGING HIGH CONCENTRATION OF GINSENG}

1 is a schematic view of a fluidized bed process machine improved in accordance with the present invention.

Figure 2 is a photograph illustrating the preparation of ginseng extract granules and pills of various sizes that can be produced by the method of the present invention.

FIG. 3 shows granules (A) used as intermediate products in Examples 5, 6 and 7 and ginseng extract pills containing 95% or more of ginseng components according to the method of the present invention. It is a photograph showing (B).

Figure 4 is a photograph showing a pill made by the tangent spray method of Example 8 according to the method of the present invention.

Brief description of reference numbers

1 --- product container

2 --- expansion chamber

3 --- exhaust flap

The present invention relates to a method for producing ginseng extract granules and pills containing a high concentration of ginseng components, and more particularly, to dry, powder, granulate and coat the ginseng extract concentrated extract with high moisture content and very high viscosity The process is carried out continuously to finally produce ginseng extract granules and pills containing up to 99.5% of ginseng components.

Korean ginseng (Panax Ginseng) has been evaluated as Korea's best specialty product because of its excellent efficacy. In particular, red ginseng is steamed and dried by steaming raw ginseng mined from the field. Part of the sugar is liberated from the basic structure of the dicyclic triterpenoid dammarane due to heat hydrolysis. Ginsenosides of the prosapogenin type (ginsenoside) Rg3, Rg2, Rg5, Rh2, Rh4 and the like are known to produce unique components of red ginseng.

Recently, red ginseng in a form that maximizes the efficacy of ginseng is widely used in various formulations, and processing methods for increasing ginsenoside components have been introduced.

However, the 100% concentrated ginseng extract is excellent in its efficacy, but when it is actually taken or ingested, the liquid gets dirty at the entrance of the bottle, and the bottle lid does not open, making it difficult to take a certain amount each time. There is discomfort to dissolve. In order to alleviate this inconvenience, concentrate powder, granule type tea, powder capsules and pills have been introduced, but these products have a problem that the content of the concentrated ginseng extract is low, up to 45% or less. The ginseng extract concentrated to 100% has a very high viscosity and a very strong hygroscopicity of the powder, so it is impossible to prepare granules or pills having a high ginseng content using a conventional method or a device such as a recirculator or a spray drying method. Carrier) material had to be added, so the concentrated ginseng extract content contained in the final product was low.

As an example of the prior art as described above, Korean Patent Application No. 194-37571 discloses a method for preparing ginseng tea containing up to 40 to 45% of ginseng extract from 10 to 18% of general products. Inlet is spray-dried at 170-190 degreeC and outlet sms 95-110 degreeC, and exceeds 90 degreeC which is the temperature at which a ginsenoside component is destroyed. Republic of Korea Patent Application No. 2000-24006 relates to a method of manufacturing granule-type concentrated ginseng, it is difficult to obtain a granular product of a good shape in the process of long grinding process and re-crushing the dried product after plate freeze-drying, When it comes in contact with the outside air there is a problem that the mass is formed by absorbing moisture. In addition, Korean Patent Application No. 2002-06318 is a method for producing spherical microcapsules containing red ginseng or ginseng extract, and the content of pure ginseng extract contained in the final product is less than 57% and the size of spherical granules of 1000 to 1200 um in size. It is described as using 100% spray-dried extract powder (ginseng powder), but the exact method is not described.

The commercial scale production of 100% ginseng extract powder by spray drying method evaporates the moisture contained in the particles immediately after spraying, but irregularly presses on the wall as the powder passes through the cyclone and collects in the collector, and the moisture hygroscopicity is very strong. As it is absorbed and moistened again during the transfer from the collector, the product value is lost and normal handling is impossible.

Therefore, currently marketed ginseng extract pills are made by mixing ginseng extract with dried red ginseng powder, rice powder, crystalline cellulose, glutinous rice powder, green tea powder, etc. without extract as a carrier for adsorption of extract, This process is repeated to increase the ginseng content, so the process takes a long time and the ratio of the actual extract component content in the final product is also low.

On the other hand, Korean Patent Application No. 2003-87421 relates to a method for producing honey powder and honey powder food, the composition ingredients by weighing 5 to 95% by weight of the honey raw powder and 95 to 5% by weight of the predetermined additive powder To prepare. ” However, in the embodiment, only up to 30% of the honey stock solution (interpreted as a honey stock solution) was used, and a drying method also used a known method. Known methods can be used to obtain powders containing up to 40% honey, but increasing the honey content beyond that has difficulty in practical application due to the hygroscopicity of dried fructose.

In the present invention, to solve the problems described above and to produce a ginseng extract granules and pills containing a higher content of ginseng components, ginseng extract by using a fluidized bed process machine and adjusting the manufacturing conditions of ginseng extract, In addition to relieving the inconvenience caused when taken intact as well as a small amount of ginsenosides that can satisfy the daily ginsenoside components needed to prepare a ginseng extract granules and pills The present invention has been completed.

It is an object of the present invention to provide a method for producing ginseng extract granules and pills containing a high concentration of ginseng components, which is easy to control the particle size and excellent in the marketability of the obtained product.

Another object of the present invention to provide a ginseng extract granules and pills containing a high concentration of ginseng components provided by the method.

In one embodiment, the present invention provides a method for preparing ginseng extract granules and pills containing high concentration of ginseng components using a fluidized bed process machine.

In another aspect, the present invention

Injecting a seed for manufacturing pills into a product container of a fluidized bed process machine;

Spraying a ginseng extract solution on the seed to grow the ginseng extract on the seed to grow ginseng extract particles of a desired size; And

It provides a method for producing ginseng extract granules and pills comprising coating the outer surface of the particles obtained in the step with a moisture-proof material.

In the present invention, the fluidized bed process can be efficiently dried by the surface exposure while the liquid, powder and granules are fluidized by air pressure in a closed space, at the same time the fine powder is increased by spraying the binder to form spherical granules And encapsulated products can be obtained.

As shown in FIG. 1, the fluidized bed process machine is a conical product container 1, a cylindrical expansion chamber 2 in which fluidization takes place, filter shaking and an exergy flap part 3. (exhaust flap part) consists of basic components. Peripheral devices include cooling and heating devices for temperature control of inlet air, nozzles, divided into top or bottom spray depending on the nozzle position, and the batch type system is connected side by side. There is a continuous spray method and a tangent spray system equipped with a rotating disk inside a product container.

In the present invention, a modified fluidized bed process system (Fluid-bed processing system: Uni-Glatt and GPCG3.1 model of Glatt Co., Ltd. Germany) is used to modify, it is a device that can perform the drying, granulation and coating process in a continuous operation . Conventional fluidized bed process machines have a ratio of the depth of the product container 1 at the bottom to the depth of the stop expansion chamber 2 at about 1: 2. In the present invention, by increasing the depth ratio of the product container (1) and the depth of the expansion chamber (2) than the depth ratio of the conventional general fluidized bed process machine to improve the drying efficiency in the manufacture of the ginseng extract granules and pills of the present invention, powder Or sufficient flow distance and fluidization zone of the granules (FIG. 1). The ratio of the depth of the product container (1) to the depth of the expansion chamber (2) may vary depending on the size and the production volume of the manufacturing space of the granules and pills of the present invention, but preferably 1: 1.5 or more, more preferably 1 : 2 to 7, still more preferably 1: 2.5 to 4.5.

By controlling the ratio of the depth of the product container 1 to the depth of the expansion chamber 2, sufficient fluidization of the particles to be produced in order to maintain their advantages more efficiently in a state where the fluidization distance and fluidization area of the particles are sufficiently secured A suitable blower capacity can be selected for this purpose. In the case of the granules and rings produced in the present invention, the weight of one particle having a diameter of 2 mm or less is 0.0035 g, the bulk density (g / ml) is 0.85, and the size of 2 mm is 0.015 g and 0.65, respectively, and the size of 3 mm is 0.035 g and 0.62, respectively. The 4mm size ranges from 0.075g and 0.595, and the 5mm size ranges from 0.125g and 0.595 and 6mm, respectively, to 0.225g and 0.595, respectively, so the blower has a fluidization distance of at least 1M based on the 6mm sized ring. It should be possible to float, and it is preferable to use a blower having such a blowing capacity.

In the spraying method of ginseng extract, any of the spraying methods known to those skilled in the art, such as the upper, lower, or tangent spray method, can be used, but preferably, the lower spray method or tangent spray method. As an example, the lower spray method is easier to increase the size of the pill than the upper spray method, and the water removal time can be lengthened by increasing the distance and the fluidization state of the sprayed ginseng extract particles or powder and granules. High efficiency allows uniform drying, and produces uniform spherical ginseng extract pills without irregular agglomeration between particles. As another example, ginseng while slowly injecting powder into a rotating disk in a tangent spray system equipped with a rotating disk of the powder or fine granules obtained in the upper or lower spray method. Spraying the extract solution can quickly increase the size and produce a much more uniform shaped pill.

Typically, the ginseng extract concentrated extract has a water content of 33 to 35%, has a viscosity of 70 to 75 Brix, containing 67 to 65% solids, and is highly viscous, and in the dry powder state, the hygroscopicity is strong, thus, it is presented in the present invention. It is not easy to obtain a content of 99.5% as a ginseng component. To this end, it is important to control the fluidization of the granules or particles during which the spraying amount and spray rate of the extract solution, the rate of opening of the ext flap, or the increase in the particle size are in progress, and to maintain the product container temperature optimally. That is, the already produced ginsenoside component is decomposed at a contact temperature of 90 ° C. or higher, and when the temperature is increased to 95 to 100 ° C. or higher, the dried powder dissolves again and causes sticking to the base wall and the filter. In order to suppress this phenomenon, it is very important to spray a very small amount of spray, for example 3 to 5 ml per minute, to sufficiently generate the initial fine particles at the beginning of the work. Next, the spray amount is increased to 10 ml per minute to promote aggregation of the fine particles, and once the spherical granules of about 1 to 2 mm are formed, the spray amount is increased to about 15 to 25 ml / min to quickly increase the size of the granules formed again. Increase in steps. As described above, in the present invention, the particle size of the ginseng extract can be arbitrarily adjusted from the powder size to the pill having a diameter of 8 mm by controlling the spray rate of the fine particles of the ginseng extract using a fluidized bed process machine.

At this time, the temperature of the initial product container should start at 50 ° C and gradually increase to evaporate the moisture accompanying the increase in spray amount, but should be maintained below 85 ° C. The preferred optimal product container temperature ranges from 70 to 75 ° C. and the fluidization of the fine particles and granules must be smoothly maintained throughout the entire process to prevent caking between the particles. Therefore, the open flap ratio of the exhaust flap gradually increases from 5% to 80 to 95%. The air distribution plate installed at the bottom of the product container is also preferable to use as many fine holes as possible to prevent smooth fluidization and agglomeration.

Using a fluidized bed process, theoretically, even without any seed initially placed in the product container, the water in the liquid droplets of the ginseng concentrate extract sprayed like a mist into the fluidized bed stream immediately evaporates to form a fine powder that acts as a seed. In the fluidized bed airflow, the powder acts as a abrasive between the powders, thereby forming 100% ginseng extract granules. However, it is difficult to control the initial fluidization and powder formation conditions, and it is inefficient due to a large amount of time spent in the early stages, and a large amount of powder is attached to the inner wall of the process chamber, resulting in raw material loss. Therefore, the present invention finally increases the raw materials and process efficiency in the manufacturing process by preparing a pill or granule by spraying the extract solution after administering an appropriate amount of seed to the product container of the process in consideration of the desired ginseng concentrate extract content. The seed used in the present invention can be used as long as the unit weight is light and bulky fine particles. In addition, the seed of the present invention may be used by dividing two or more seeds into a main seed and a sub seed and mixing them, but are not necessarily limited thereto. Specifically, the seed of the present invention uses a variety of animal and vegetable food powders in powder form, or natural or chemically synthesized food additives. More specifically, the seed of the present invention, synthetic products such as ginseng powder, chlorella powder, hemp powder, green tea powder, unsweetened powder, cheonggukjang powder, isoflavone powder, glucosamine powder, cellulose as a main component, and various dietary fiber powders , Polydextrose, mannan, pectin, carrageenan, algin, various starches, cyclodextrin, lactose, mannan, saccharide powder such as glucose or xylose powder, various amino acid powder, vitamin powder and mineral powder These may be used alone or in combination of two or more according to the properties of the material,

In addition, the seed of the present invention by giving the characteristics of the seed to the ginseng extract granules and pills prepared using the nutrient reinforcing material, taste improving material and properties improving material described below ginseng extract granule having a specific purpose And it can manufacture as a pill. Specifically, the nutrient reinforcing material is known vitamins, minerals and amino acids, etc. Taste improvement material, such as bitter taste reduction of ginseng extract for people who chew the pill, taste ingredients, sweet ingredients, There are acidic ingredients, and other spicy pepper extracts such as Oleoresin capsicum, wasabi powder, mustard powder or raw garlic dry powder can be used to prevent drowsiness of the driver. In addition, the material for improving physical properties include sodium alginate, propylene glycol esters of alginic acid, casein, sodium caseinate, sodium chondroitin sulfate, sodium carboxymethyl cellulose or calcium powder, sodium carboxymethyl starch powder, methylcellulose, sodium polyacrylate powder, pectin, Agar, gelatin, gums (Guar gum, gum arabic, Xanthan gum, Locust bean gum, etc.), carrageenan, arabinogalactan, pullulan gum, gellan gum, processed starch (alpha-starch, ester starch, toast) Starch, etc.), sodium starch phosphate, micro-fibrillated cellulose, chitosan, cyclodextrin, charcoal seed gum, mannite (D-Mannit or D-Mannitol), silica powder, silica aluminum sodium, silicic acid Calcium, calcium stearate, talc, kaolin and the like. The material for improving the properties is preferably used when the product of ginseng extract content of more than 95% final.

In a specific embodiment of the present invention, starches such as corn starch and potato starch as main seeds; Lactose; Dietary fibers such as polydextrose, pectin and mannane; One or more mixed starch, carboxy methyl cellulose, and finely ground ginseng powder are used in combination. As a sub-seed, one or more mixtures of modified starches such as dextrin, glucose, aspartame, sugar, guar gum, agar, and carrageenan are used, and the main seed and sub seed are 1 It is preferable to mix and use in the ratio of 0.1-1.0.

The main seed has a fluidizing property, and the sub seed has a weak viscosity such that the powder does not adhere to each other while fluidized at an air temperature of 50 to 85 ° C., which is sucked into the fluidized bed process, so that the ginseng extract powder is The effect of making it easy to attach to the outer surface of the seed can help form a large amount of ginseng particles in a short time.

The total amount of the seed is determined in consideration of the ginseng extract content of the final product, which can be determined by those skilled in the art of the present invention.

Ginseng extract concentrated extract having a viscosity of about 72 Brix is very viscous, so it can be transferred to the peristaltic pump only by diluting by adding water or plant extract of 20 to 40% by weight. The plant extracts include herbal extracts, garlic extracts, onion extracts, and the like, without being limited thereto. The medicinal herb extract may use a variety of known extracts, it is possible to add the efficacy of the medicinal herbs in addition to the efficacy of ginseng extract ginseng extract produced thereby. Examples of the medicinal herb extracts include, but are not limited to, jujube extract, pomegranate extract, astragalus extract, motherwort extract, mugwort extract, organ extract, medicinal mushroom extract, and the like.

In addition, the diluted ginseng extract solution, pullulan gum (pullulan gum), microfiberized cellulose (MFC, micro-fibrillated cellulose), cyclodextrin (cyclodextrin), whey protein, soy protein, skim milk powder, Granules having a ginseng component content of 50 to 95% by adding at least one compound selected from the group consisting of a suspension or an aqueous solution of sodium caseinate, casein, alginate-sodium-alginate, etc. It can be mainly used in the manufacture of pills. An appropriate amount of water is added to an amount of 1 to 5% by weight of the concentrated ginseng extract stock solution, which is added to form a suspension or an aqueous solution. The compound is injected into the fluidized bed flow to control the viscosity in the process of evaporation, powdering, and granulation of water to increase granulation and prevent adhesion between granules, and the protein component is well combined with various sugars of the extract. Increases matrix-forming and facilitates fluidization.

In the case of preparing a pill containing 95% or more of ginseng components by the method of the present invention, in order to improve the properties of ginseng extract having a very high viscosity, microfiberized cellulose (MFC), pullulan gum, Cyclodextrin, D-Mannit, Fine Silica Powder, Sodium Silico Aluminate, Calcium Silicate, Magnesium Silicate, Calcium Stearate, etc. use.

According to the present invention, up to 90% of the ginseng component may be completed to the final product in one continuous process. If you want to manufacture ginseng extract granules or pills containing 90% or more of ginseng components, it is preferable to divide by several times. In other words, the larger the size of the powder, the larger the voids, the larger the volume, and the greater the weight per unit granule or pill, which requires more energy for smooth fluidization. To compensate for this, first, the primary granules with a content of about 90 to 95% are prepared, and then the ginseng extract required for a certain amount of primary granules is coated in a manner of layering to increase the content of ginseng components in the product. You can. The granule (A) and the finally obtained pill (B) used as an intermediate product to prepare a ginseng pill containing 95% or more of ginseng components produced by such a process are shown in FIG. 3. As shown in Figure 3 granules used as intermediate products can be produced in sizes of 1 mm or less.

In one specific embodiment, the present invention provides a method for producing ginseng extract granules and pills, including an additional step, and ginseng extract granules and pills prepared by the method.

The addition process in the above means a process that is carried out in addition to the step of containing a ginseng component at a high concentration or adjusting the particle size to produce granules or pills.

According to the present invention, flavoring agents, varnishes, or coatings may be used in the fluidization process as needed. For example, vitamin C and nutrients such as sorbitol, xylitol, sugar, sweeteners, vitamins, minerals, and amino acids can be added. These compounds can mask the bitter taste of ginseng extract and Enhance lack of nutrients.

In addition, once all of the above process is completed to obtain a granule or pill of the desired size can be coated with a moisture-proof film-forming material, hydroxy propyl methylcellulose, hydroxypropyl cellulose (Hydroxy propyl cellulose ), Ethylcellulose, methylcellulose, cellulose acetate phthalate, carnauba wax, candelilla wax, petroleum wax, beeswax, palm oil (hydrogenated fat) ) And at least one selected from the group consisting of a coating agent to complete the product by coating an amount corresponding to 0.1 to 0.5% of the final weight. The ginseng extract granules and pills coated with the coating material can not only enhance the fresh and refreshing taste but also have a safe advantage in the distribution process.

In addition, if a more diverse final product is needed, the finished product made in the above example is placed back into the seed product container, and an appropriate amount in a 1-5% solution of viscous dextrin, glucose, agar, carrageenan, hydroxypropylethylcellulose, and the like. By coating the solution containing a mixture of chlorella powder, green tea powder, gold powder, silver powder, pearl powder, etc. in a layering manner, it is possible to change the color of the product to increase the completeness of the product.

In the present invention, carnauba wax, Candelilla wax, Petroleum wax and the like can also be used as a polishing agent for coating the surface of the pills.

In another aspect, the present invention provides ginseng extract granules and pills prepared according to the above method. Ginseng extract granules and pills prepared according to the method of the present invention contains more than 90% of the ginseng components, so it is easy to control the dosage and frequency. In addition, as shown in Figure 2, since it can be prepared in a variety of sized pills from powder to about 8 mm in diameter without clumping during the manufacture of the pill has the advantage of a wide choice of pills and convenient at the time of taking.

Hereinafter, the present invention will be described in more detail with reference to Examples. The following examples are merely illustrative of the present invention, but the content of the present invention is not limited to the following examples. In the following examples, 72 Brix 6-year-old red ginseng extract extract concentrate (total saponin content: 150mg / 1g extract) of 35% moisture and 65% solid content was used as the ginseng extract concentrate. In addition, in the embodiment of the present invention, a) Representative examples of granules and pill preparations b) Examples of nutrient reinforcement c) Examples of taste improvement d) Examples using herbal extracts and e) other special examples Was carried out.

Granule  And Circulating  representation Example

Example  1: red ginseng containing 50% of red ginseng Extract  Manufacture of rings

At the bottom of the product container of the fluidized bed process machine was mounted an air diffuser plate with fine holes and 400 g of corn starch as the main seed and 95 g of dextrin as the sub seed were added. 770 g of red ginseng stock solution was weighed and dissolved by adding 250 g of warm water. The prepared product container was mounted on the fluidized bed apparatus and the initial ex flap was 10% to operate the apparatus to check the fluidization state of the seed while raising the temperature. When the product container temperature reached 50 ℃, the peristaltic pump was operated to inject diluted red ginseng extract solution. The pumping rate of the red ginseng extract solution was carried out in the initial injection rate range of 5 to 10 ml / min when the seeds are large. After checking the fluidization state from time to time, the red ginseng solution injection rate was gradually increased, and the product container temperature was maintained in the range of 70 to 80 ° C., and the granules gradually increased, and the rate of opening of the flap was also increased. After the red ginseng extract solution has been injected, spraying a solution of 5 g of hydroxypropyl cellulose in 100 ml of water can reduce the temperature of the product container to a range of 50 to 60 ° C. After spraying, the temperature of the product container was lowered to room temperature, the work was completed, and the product was collected to obtain 970 g of granules having a diameter of 1.5 to 3 mm, and the production efficiency was 97% compared to the raw materials.

Seed: 400 g of corn starch + 95 g of dextrin = 495 g

Ginseng Extract: Red ginseng extract 770 g x Solid 65% = 500.5 g

Hydroxypropylmethylcellulose: 5 g = 5 g

-------------------------------------------------- ----------------

                                           Total amount of raw materials: 1000.5 g

Red Ginseng Extract Content (%) = 500.5 g / 1000.5 g X 100 = 50.02%

Final granules produced (size 1.5 to 3 mm): 970 g

Example  2: red ginseng containing 70% of red ginseng Extract  Manufacture of rings

Polydextrose was used as the main seed and agar powder was used as the sub seed, and the conditions of the fluidized bed process machine were set as in Example 1. First, casein-sodium (sodium caseinate) was dissolved in 200 g of water, mixed with 1180 g of red ginseng extract solution, and injected with palm oil as an external coating agent after lowering the product container temperature to 35 to 40 ° C. Finally, 1070 g of product having a size of 2 to 4.5 mm were obtained.

Seed: Polydextrose 200g + Agar Powder 95g = 295 g

Ginseng Extract: Red ginseng extract 1180 g x 65% solids (= 767 g solids) +

              Casein-sodium 25 g = 792 g

Palm oil: 5 g = 5 g

-------------------------------------------------- -------------------

                                                 Total amount of raw materials: 1092 g

Red Ginseng Extract Content (%) = 767 g / 1092 g x 100 = 70.24%

Final granules produced (2 to 4.5 mm): 1070 g

Example  3: red ginseng containing 80% of red ginseng Extract  Manufacture of rings

The operating conditions of the fluidization process were the same as in the above example, and the content of the added components was used as follows. As the extract content increased, smooth fluidization was maintained. The ratio of the main seed to the sub seed was 1: 1 and the whey protein added to the extract solution was dissolved separately and mixed with the red ginseng extract solution. The final coating material was coated with ethylcellulose dissolved in ethanol and the product size was approximately 0.5 to 2.5 mm. The powder size can be increased quickly by increasing the injection amount by increasing the rotation speed of the peristaltic pump while lowering the pressure of the nozzle spraying the red ginseng extract solution.

Seed: Lactose 95g + Glucose 95g = 190 g

Ginseng Extract: Extract Stock 1260 g x Solid 65% (Solid 819 g) +

                  Whey protein 5 g = 824 g

Ethylcellulose: = 5 g

-------------------------------------------------- -------------------

                                                Total amount of raw material = 1019 g

Red Ginseng Extract Content (%) = 819 g / 1019 g X 100 = 80.37%

Final granules produced (0.5 to 2.5 mm): 1003 g

Example  4: red ginseng containing 90% of red ginseng Extract  Manufacture of rings

The operating conditions of the fluidization process were the same as in the above example, and the content of the added components was used as follows. As diluents, solutions of microfibrillated cellulose and sodium alginate, respectively, were prepared and mixed with the diluted red ginseng extract solution. The final coating material was coated with hydroxypropylmethylcellulose.

Seed: 60 g + Dextrin 25 g = 85 g

Ginseng Extract: Extract Stock 1400 g x Solid 65% (Solid 910 g) +

     5 g fine fibrous cellulose (MFC) + 5 g sodium alginate = 920 g

Hydroxypropyl methyl cellulose: = 5 g

-------------------------------------------------- ---------------------

                                                   Total amount of raw material = 1010 g

Red Ginseng Extract Content (%) = 910 g / 1010 g x 100 = 90.1%

Final granules produced (0.2 to 2 mm): 970 g

Example  5: red ginseng containing 95% of red ginseng Extract Pilled  Produce

To prepare a red ginseng extract pill containing a high content of red ginseng of 95%, an intermediate product having a ginseng extract content of 90% of 0.5 to 2 mm in diameter was prepared as in Example 4 above.

Seed: 60 g of pectin + 30 g of guar gum = 90 g

Ginseng Extract: Extract Stock 1400 g x Solid 65% (Solid 910 g) +

              Casein 5 g + pullan gum 5 g = 920 g

-------------------------------------------------- --------------------

                                                  Total amount of raw material = 1010 g

Red ginseng extract content (%) of intermediate product = 910 g / 1010 g x 100 = 90.1%

Intermediate product output (0.5 to 2mm size): 975 g

200 g of the intermediate product granules prepared as described above were added to the product container again as a secondary seed, followed by injecting the next solution while fluidizing. To a solution of 600 g of red ginseng extract stock solution, a suspension of 2.5 g of cyclotextrin and 2.5 g of isolated soy protein, respectively, was mixed and then moisture-proof coated with 5 g of bees wax.

Medium product 200 g: Pure ginseng content = 180 g

                                              Carrier material = 20 g

Secondary ginseng spray solution: Extract 600 g x 65% solids (390 g solids)

      + Cyclodextrin 2.5 g + soy protein isolate 2.5 g = 395 g

Bees wax 5g = 5 g

-------------------------------------------------- --------------------

                    The total amount of raw materials is 180 g + 20 g + 395 g + 5 g = 600 g

Red Ginseng Extract Content (%) = (180 g + 390 g) / 600 g x 100 = 95%

Final produced granules (2.5 to 5.0 mm): 585 g

Example  6: red ginseng containing 98% of red ginseng Extract Pilled  Produce

In Example 5, 200 g of the intermediate product granule of 90% pure ginseng made of primary was added to the product container as a second seed, followed by fluidization, followed by injection of the following solution. 1990 g of red ginseng extract solution was diluted, 5 g of mannite was dissolved in warm water, mixed, sprayed, and then moisture-coated with 5 g of carnauba wax to obtain a pill product.

Medium product 200 g: Pure ginseng content = 180 g

                                             Carrier material = 20 g

Secondary ginseng spray solution: Pure ginseng content 1990 g x 65% solids (1293.5 g solids)

           + 5 g of carrier material mannit = 1298.5 g

Carnauba wax 5 g = 5 g

-------------------------------------------------- ---------------------

                  The total amount of raw materials is 180 g + 20 g + 1293.5 g + 10 g = 1503.5 g

Product Red Ginseng Extract (%) = (180 g + 1293.5 g) /1503.5 g x 100 = 98%

Final granules produced (2 to 6.5 mm): 1460 g

Example  7: Red ginseng containing 99.5% of red ginseng Extract  Manufacture of rings

7-1. When using intermediate granules containing 90% red ginseng as seeds

In Example 5, 100 g of the intermediate product granule of 90.1% of red ginseng prepared as a seed was put into a product container for use as a seed, and then the following solution was injected while fluidizing.

1500 ml of hot water was added to 6125 g of ginseng extract to dissolve it. 2.5 g of fine silica powder and 2.5 g of cyclodextrin were prepared by mixing with a ginseng solution, sprayed, and then moisture-coated with 5 g of carnauba wax. The higher the content, the finer the fluid injection and the finer the pump injection volume. Finally, high concentration ginseng pills of 7 mm size were obtained.

Intermediate product: (100g) Pure Ginseng Content = 90.1 g

                                                  Carrier material = 9.9 g

Secondary ginseng spray solution: Pure ginseng content 6125 g X solid 65% (solid 3981.25 g)

  +2.5 g of fine silica powder +2.5 g of cyclodextrin

Carnauba wax = 5 g

-------------------------------------------------- ---------------------

                                              The total amount of raw materials is 4091.25 g

Red Ginseng Extract Content (%) = (90.1 g + 3981.25 g) /4191.25 X 100 = 99.51%

Final produced ring (3.5-7mm): 4010 g

7-2. When using intermediate granule with 95% red ginseng as seed

As a carrier material, 20 g of corn starch, 10 g of glucose and 10 g of finely ground red ginseng powder were put into a product container, and then fluidized while spraying red ginseng extract 1540 g + 10 g of water-soluble casein with a specially controlled fine diameter of 0.5 g. Spherical granules having a red ginseng component content of 95% to 2.5 mm were prepared. Using this as a secondary seed, 100 g was put back into the product container, and the next ginseng solution was injected while fluidizing. 5200 g of diluted ginseng extract solution, sprayed with 5 g of water-soluble casein, a suspension containing 3 g of microfibrillated cellulose (MFC) and 2 g of calcium stearate, followed by spraying Moisture-proof coating was carried out with 2.5 g of oxypropylethylcellulose (HPMC) to finally obtain a ginseng pill of about 6 mm.

Primary 95% Seed Preparation: 20 g of corn starch

                    10 g of glucose

                    10 g of fine ground ginseng powder

Ginseng Extract: 1540g (solids 1540g x 0.65 = 1001g) + Water-soluble Casein 10g

-------------------------------------------------- ---------------------

                                                   Total raw materials: 1051 g

Red ginseng extract content (%) of the product = 1001g / 1051g X 100 = 95.24% to prepare a primary seed product.

Again 100 g of primary seed product:

            Pure Ginseng 95.24 g

            4.76 g of carrier material

Ginseng solution for secondary spraying:

            5200 g of ginseng extract stock (3380 g as a solid)

            5 g of water-soluble casein

            3 g of microfibrillated cellulose (MFC)

            2 g of calcium stearate

Final coating: 2.5 g of hydroxy propyl ethyl cellulose (HPMC)

-------------------------------------------------- ---------------------

Total Raw Material Amount: 3492.5 g

Total ginseng content: 95.24 g + 3380 g = 3475.24 g

Pure Ginseng Content of Final Product: 3475.24 g / 3492.5 g X 100 = 99.51%

Final produced ring (3 to 6.5mm): 3430 g

Example  8: contains more than 95% of red ginseng by tangent spray method Pilled  Rapid size up

Ginseng extract solution prepared in advance while constantly injecting 1000 g of red ginseng content 95% fine granules of 95% red ginseng prepared in Example 7-2 into the rotating rota disk (mixed spray solution of ginseng extract stock 500 g + fine silica powder 5) When sprayed in proportion to the rate of 1000g of fine granules to be injected and finally coated with a solution of 2.5g of hydroxypropyl ethyl cellulose (HPMC) to obtain a large diameter product as shown in FIG.

1000 g of 7-2 fine granules for seed:

        Pure Ginseng 1000g X 95.24% = 952.4g

        Carrier material 47.6 g

Ginseng solution for spraying:

        Pure Ginseng Solid 500g X 65 = 325g

        5g fine silica powder

2.5 g of hydroxypropyl ethyl cellulose (HPMC)

-------------------------------------------------- ------

Total raw material amount 1332.5g

Total ginseng amount 952.4 + 325 = 1277.4 g

Pure Ginseng Content of Final Product 1277.4g / 1332.5g X 100 = 95.86%

1280 g of the final produced ring (6-8 mm) are obtained.

Nutritional fortification Example

The recommended daily intake of saponin in ginseng is usually in the range of about 210 to 420 mg. Take 4 to 6 pills once a day for 6 mm sized rings containing 90% or more of the extract prepared in Example 4 to obtain the recommended intake of saponin. Although it can satisfy, as in Example 1, the content of about 50% of the product can be given another property with the nutrient-enhanced product described below in consideration of some inconvenience to be taken at least twice a day.

Here, as in Example 1 above, other conditions were the same, and instead of corn starch and dextrin used as seeds, 495 g of the nutrient mix of about 508 g blended below was used as a seed and the size of the pill was about 6 mm.

That is, Vitamin A 30g, Vitamin D (Cholecalciferol) 7.5g, Vitamin C (Ascorbic acid) 21g, Vitamin E (dl-α-Tocopheryl Acetate) 12g, Vitamin B1 (Thiamine Mononitrate) 0.9g, Vitamin B2 (Riboflavin) 0.75g , Vitamin B6 (Pyridoxine hydrochloride) 0.75g, Vitamin B12 (Cyanocobalamin) 1mg, Calcium carbonate 9g, Folic acid 0.15g, Niacin amide 15g, Calcium pantothenate 0.9g, Biotin 5mg, Magnesium Oxide 4.5g, Zinc gluconate 0.45g, Potassium iodide 5mg0.005, Potassium citrate 1.5g, Manganase sulfate 0.2g, Sodium selenite 5mg, Lycopene powder 9g, Sorbitol 100g, Xylitol 80g, Stearic acid 60g, Calcium citrate 25g, Carrageenan 75g, Phenylalanine 55g Used.

Seed: Nutrient Mix = 495 g

Ginseng Extract: Red ginseng extract 770 g x Solid 65% = 500.5 g

Hydroxypropylmethylcellulose: 5 g = 5 g

-------------------------------------------------- ----------------

                                           Total amount of raw materials: 1000.5 g

Red Ginseng Extract Content (%) = 500.5 g / 1000.5 g X 100 = 50.02%

Final produced granule (size 6 mm or more): about 550 g was obtained.

1 g of red ginseng extract used in the present invention contains saponin content of 150 mg (building standard content is 230 mg / 1 g DM), so the recommended daily intake of saponin is in the range of about 210 mg to 420 mg, and the actual 6mm pill weight is about 0.22 Since g is taken twice a day, about 5 pills at a time (2.2g in total weight), saponin intake is 253mg per day, which satisfies the recommended amount, and it is also a product that can take enough nutrients. In addition, in the nutrient-enriched product, the content of various nutrients contained in about 10 pills of the finished product can be adjusted to be included in the final product by adding or subtracting the total amount used as the seed in consideration of the recommended daily intake standard of nutrients.

Of taste improvement Example

In general, when ginseng extract is dissolved in hot water and used, bitterness is very strong, so it is usually taken with sweeteners. However, the ring of the present invention is most ideal when swallowed directly with water, but some individuals would like to take a bite by ignoring the advantages of the present invention. Therefore, the present embodiment was carried out to give a bitter taste shielding effect in order to overcome the above problems. The flavors are divided into sweeteners, acidulants and seasonings that do not belong to these mild flavorings. Sweeteners are based on sugar, and xylose, glucose, sodium glycyrrhinate, oligosaccharides, sorbitol, and maltitol are similar in sweetness to sugar, but stevia (stevioside), aspartame, lacturose, doumatin, saccharin Back is 50 to 500 times sweeter than sugar and domatine is more than 5000 times stronger. Acidulants include citric acid, gluconate solution, lactic acid, sodium fumarate, and malic acid. Seasonings include alanine, sodium inosinate, sodium guanylate, glycine, glutamic acid, sodium succinate, theanine, calcium ribonate and the like. The purpose of the present invention is to mask the bitter taste, so that the blending ratio of the sweetener, the acidulant and the seasoning material is 40 to 80%, 20 to 40%, and 0 to 10%, respectively, in consideration of the strength of each taste component. The combined mixture was added in the range of 0.1-5% by weight of the ginseng extract stock weight. Specifically, the bitter taste of the extract could be alleviated by 80% or more when 0.5% of the taste improving mixture, which is a combination of 75% sweetener, 20% acid and 5% seasoning, was added to the measured extract stock.

Using herbal extract Example

Since ginseng extract has high viscosity and is applied by adding an appropriate amount of water, various herbal medicine extracts can be used instead of water to improve the inconvenience of packing them in bags or mask the taste of pomegranate, motherwort, wormwood, etc. Take advantage of the advantages of the invention.

In this embodiment, the jujube or pomegranate extract has a solid content of 30% or more or a slight viscosity due to sugar, so that the ginseng extract granules and ginseng extract content used in place of water in the example below 90% A pill was prepared, and the hot water extract of Astragalus, Motherwort, Mugwort, Ogapi or medicinal mushroom with almost no solids and sugars was used instead of water in the Example of ginseng extract content of 90% or more. Ginseng extract was diluted in an amount corresponding to 20-40% of the total weight of ginseng extract based on the moisture content contained in the extract, and the following manufacturing process was carried out in the same manner as in the above example. The prepared pills were confirmed to have both the characteristics of the ginseng extract and the herbal extracts prepared in the above examples.

Etc Example

The unique and beautiful appearance of the final product has a great influence on the degree of consumer's perception of product selection preferences and quality. Therefore, the following examples were carried out to increase the marketability of the final product and to expand the scope of application.

1) Gold powder, silver powder coated Pill  Produce

In the above embodiment, HPMC, Wax was applied in the final step of coating the final process, based on 500g of the weight of the ring made in the fluidized bed process, prepared by spraying 5g of gold powder mixed with 5% starch solution and sprayed Finally, the product was coated with HPMC and Wax to obtain a gold powder coated product.

2) Manufacture of rings coated with pearl powder

Pearl coated pill products are particularly suitable for women, so the seed also uses isoflavone powder to enhance the product's characteristics. The seed pectin and guar gum 90g used in the preparation of the 95% extract content of Example 5 were replaced with 90 g of isoflavone powder, and 500 g of the weight of the ring made inside the fluidized bed process at the stage before final external coating with beeswax. On the basis of this, a suspension of 5 g of pearl powder mixed in a 5% starch solution was prepared, sprayed, and finally wax-coated to finish.

3) Manufacture of rings coated with chlorella powder that emphasizes natural green color

Chlorella powder is easy to apply to the above examples because it is well soluble in water. That is, 10 to 50 g of chlorella was first dissolved in 5% starch solution or water measured before dissolving HPMC and sprayed by dissolving HPMC, based on 500g of the weight of the ring made inside the fluidized bed process in the final external coating step. As a result, a dark green ring was obtained. If you use green tea powder instead of chlorella, you can get a light greenish green ring.

4) Preparation of rings containing and coated with powders containing ingredients that stimulate taste and smell

In case of drowsiness while driving, candy has been introduced with a unique herb flavor that gives a very refreshing and cool feeling to the throat.However, in case of severe drowsiness, it is best for the driver to rest for a while. If you must drive, you have no other measures. Spicy red pepper powder, wasabi powder, mustard powder, raw garlic juice or powder is very strong irritant and accompanied by a severe squeeze, so the effect of defeating drowsiness in an instant. That is, 0.1 to 5% of the weight of the ginseng extract raw material measured by mixing at least one of fine powder of hot pepper, wasabi powder, mustard powder, oleoresin capsicum, raw garlic juice or powder 70% of the amount used in the above-mentioned embodiment by mixing with the extract is mixed with the extract to prepare an extract ring, and then the remaining 30% of the amount is mixed with the coating material in the final coating process with HPMC, etc. Used. Therefore, when viewed as a spicy ingredient of red pepper, it is preferable to adjust the content of the capsaicin ingredient content in the range of 150 ~ 350mg / ring product 100g relative to the weight of the final ginseng ring produced.

According to the method of the present invention, ginseng extract granules and pills can be prepared by a series of continuous processes using a fluidized bed process machine, so that the content of ginseng components can be controlled from high to low concentrations in comparison with conventional granules and pills. It is easy to take, has high hygroscopicity, high production efficiency, easy to mask bitter taste, and can produce products of various sizes and appearances.

Claims (11)

Injecting one or more pill preparation seeds selected from the group consisting of powdered animal and vegetable food powders, natural food additives, chemically synthesized food additives, taste enhancers, and nutrient supplement additives to a product container of a fluidized bed process machine; Spraying a ginseng extract solution on the seed to grow the ginseng extract on the seed to grow ginseng extract particles of a desired size; And The outer surface of the particles obtained in the step is hydroxy propyl methylcellulose, hydroxypropyl cellulose, ethyl cellulose, methyl cellulose, cellulose acetate phthalate, carnauba wax ( And coating with at least one moisture proof material selected from the group consisting of Carnauba wax, Candelilla wax, Petroleum wax, Beeswax, and Palm oil (Hydrogenated fat). Ginseng extract granules or a method for producing a pill. The method of claim 1, wherein the fluidized bed process machine has a ratio of the depth of the product container (1) to the depth of the expansion chamber (1) of between 1: 2 and 7. The method of claim 1 wherein the product container temperature of the fluidized bed process is maintained at 50 to 85 ° C. The method of claim 1, wherein the seed is composed of only the main seed or a mixture of the main seed and the sub seed. The method of claim 4, wherein the main seed and the sub seed are mixed in a weight ratio of 1: 0.1 to 1.0. delete The method of claim 4, wherein the main seed is from the group consisting of starch, lactose, polydextrose, pectin, met, modified starch, carboxymethylcellulose, fine ginseng powder, dextrin, glucose, aspartame, sugar, guar gum, agar and carrageenan. At least one component selected. The method of claim 4, wherein the sub seed is at least one component selected from the group consisting of starch, glucose, aspartame, sugar, guar gum, agar, and carrageenan. The method of claim 1, wherein the ginseng extract is water, plant extracts, pullulan gum, microfiberized cellulose, cyclodextrin, whey protein, soy protein isolate, skim milk powder, casein-sodium, casein, alginate-sodium, mannite, Method of using a mixture of one or more selected from the group consisting of fine silica powder, silica silica sodium, calcium silicate, magnesium silicate and calcium stearate. The method of claim 1, comprising coating at least one component selected from the group consisting of flavors, sweeteners, nutritional supplements, varnishes, colorants, and coatings prior to coating with the moisture proof material. Ginseng extract granules or pills prepared by the method according to any one of claims 1 to 5 and 7 to 10, wherein the ginseng extract granules or pills of ginseng extract content is 50 to 99.60% by weight. Ginseng extract granules or pills.

Images