KR100874221B1 - Body fluid measuring device - Google Patents

Abstract

The present invention is a device for extracting body fluid through the skin, and measuring the predetermined component of the body fluid. Body fluid component measuring apparatus of the present invention is a reagent paper; Located in the upper portion of the reagent paper, the penetrating member for penetrating the skin to extract the body fluid to the capillary phenomenon; A push member for moving the penetrating member to a forward position for extracting body fluid and to a retracted position for returning the penetrating member from which body fluid is extracted to its original position; A pestle for breaking the penetrating member such that the body fluid extracted by the penetrating member falls into the reagent paper; A detection member for detecting a component of a body fluid provided to the reagent paper; And a display member for displaying the result detected by the detection member.

Description

Body fluid component measuring device {APPARATUS FOR MEASURING OF BODILY FLUID COMPOSITION}

1 is a side cross-sectional view showing the configuration of a body fluid component measuring apparatus according to an embodiment of the present invention.

2 is a plan sectional view showing the configuration of a body fluid component measuring apparatus according to an embodiment of the present invention.

3 is a cross-sectional view showing a state in which the penetrating member is moved to the forward position by the push member in FIG.

4 is a perspective view showing a disposable kit.

5A and 5B are views illustrating a process of extracting blood from a penetrating member at a forward position and providing a extracted blood to reagent paper.

6A and 6B are views showing an example in which a disposable kit consisting of reagent paper and a penetrating member is employed.

* Explanation of symbols for the main parts of the drawings *

100: case 200: disposable kid

210: reagent paper 220: through member

300: supply member 400: push member

500: detection member 600: display member

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a bodily fluid component measuring device, and more particularly, to extract bodily fluid through skin and to measure a predetermined component of the bodily fluid.

Recently, as the number of diabetics increases, self-blood glucose measurement, which monitors the fluctuation of blood glucose level by itself, has been recommended.

This blood glucose level is measured by mounting a test strip (test paper) colored according to the amount of glucose in the blood, supplying and developing blood to the test strip, and colorizing the color. By using a blood glucose measurement device to quantify the blood sugar level.

Diabetic patients should take their own blood sugar test daily to measure their blood sugar levels and manage their disease to maintain a constant blood sugar level. In order to perform the blood glucose test, blood must be collected, and a body part such as a finger is usually wounded using a so-called lancing device. Then, by squeezing or pressing the wound of the skin to obtain blood, the necessary blood is obtained from the wound of the skin. The blood from the wound is then supplied to the test strip (reagent) of the glucose measuring device.

As described above, a lancing process for wounding skin using a lancing device, a squeezing process for squeezing blood from a skin wound, and a process for measuring blood sugar by dropping the obtained blood on a test strip of a measuring device are separately performed. Because it is carried out, operability is inferior.

In addition, there was a problem that the patient (user) must always carry the lancing device, the test strip and the blood glucose measurement device together.

In particular, in the case of an unexperienced patient in the process of collecting blood, over-pressing (pressing) the wound on the skin not only produces more blood than necessary, but also less than an appropriate amount of blood. There was a problem.

SUMMARY OF THE INVENTION An object of the present invention is to provide a bodily fluid component measuring apparatus in which a process of wounding the skin, collecting a body fluid, and measuring a component of the body fluid can be continuously performed.

It is also an object of the present invention to provide a bodily fluid component measuring apparatus capable of collecting and inspecting bodily fluids without causing excessive pain.

Another object of the present invention is to provide a bodily fluid component measuring apparatus capable of automatically extracting bodily fluid from the skin by using capillary phenomenon.

Another object of the present invention is to provide a body fluid component measuring apparatus capable of measuring a predetermined component in a body fluid accurately and reliably in a short time.

According to a feature of the present invention for achieving the above object, an apparatus for extracting and measuring a body fluid (bodily fluid) comprises a reagent paper; Located in the upper portion of the reagent paper, the penetrating member for penetrating the skin to extract the body fluid to the capillary phenomenon; And a supply member for supplying the bodily fluid extracted by the penetrating member to the reagent paper.

According to an embodiment of the present invention, the supply member includes a pestle for breaking the penetrating member such that the body fluid extracted by the penetrating member falls into the reagent paper.

According to an embodiment of the present invention, the penetrating member and the reagent paper are fixed to the reagent paper by an elastic support such that the penetrating member and the reagent paper are made of one kit.

According to an embodiment of the present invention, the penetrating member is made of a microcapillary tube of a size capable of extracting body fluid through a capillary phenomenon.

According to an embodiment of the present invention, the microcapillary tube has an inlet through which the body fluid is sucked by the capillary phenomenon, a passage through which the body fluid sucked through the inlet is received, and an outlet through which air in the passage can escape.

According to an embodiment of the present invention, the outer diameter of the microcapillary tube is 0.5mm to 0.05mm, the inner diameter is 0.4mm-0.04mm.

According to an embodiment of the present invention, the apparatus further includes a push member for moving the penetrating member so that one end of the penetrating member penetrates the skin.

According to an embodiment of the present invention, the apparatus further includes a push member for moving the penetrating member to a forward position for body fluid extraction and to a retracted position for returning the penetrating member from which the body fluid is extracted to its original position.

According to an embodiment of the present invention, the apparatus further includes a detection member for detecting the component of the body fluid provided to the reagent paper, and a display member for displaying the result detected by the detection member.

According to a feature of the present invention for achieving the above object, an apparatus for extracting and measuring a body fluid (bodily fluid) comprises a reagent paper; Located in the upper portion of the reagent paper, the penetrating member for penetrating the skin to extract the body fluid to the capillary phenomenon; A push member for moving the penetrating member to a forward position for extracting body fluid and to a retracted position for returning the penetrating member from which body fluid is extracted to its original position; A pestle for breaking the penetrating member such that the body fluid extracted by the penetrating member falls into the reagent paper; A detection member for detecting a component of a body fluid provided to the reagent paper; And a display member for displaying the result detected by the detection member.

According to an embodiment of the present invention, the penetrating member and the reagent paper are fixed to the reagent paper by an elastic support such that the penetrating member and the reagent paper are made of one kit.

According to an embodiment of the present invention, the penetrating member has a capillary tube having an inlet through which the body fluid is sucked, a passage through which the body fluid sucked through the inlet is received, and an outlet through which air in the passage can escape. Is done.

For example, embodiments of the present invention may be modified in various forms, and the scope of the present invention should not be construed as being limited by the embodiments described below. This embodiment is provided to more completely explain the present invention to those skilled in the art. Accordingly, the shape of the elements in the drawings and the like are exaggerated to emphasize a clearer description.

Hereinafter, an embodiment of the present invention will be described in more detail with reference to FIGS. 1 to 6B. In the drawings, the same reference numerals are given to components that perform the same function.

The bodily fluid component measuring apparatus of the present invention is a device that collects bodily fluid through the epidermis (skin) using capillary action and measures a predetermined component of the bodily fluid. The part (the penetrating part) in the epidermis involved in the collection of the body fluid is preferably a finger, but besides this, for example, the palm, the palm, the side of the hand, the arm, the thigh and the like can be mentioned.

In the following, the body fluid is blood, and the body fluid component measuring device (blood sugar measuring device) in the form of puncturing the epidermis of the fingertip (finger finger) will be described as a representative.

EMBODIMENT OF THE INVENTION Hereinafter, the bodily fluid component measuring apparatus of this invention is demonstrated in detail based on suitable embodiment shown to an accompanying drawing.

1 is a view showing the configuration of a body fluid component measuring apparatus according to an embodiment of the present invention. 2 is a plan sectional view showing the configuration of a body fluid component measuring apparatus according to an embodiment of the present invention. 3 is a cross-sectional view showing a state in which the penetrating member is moved to the forward position by the push member in FIG.

1 to 3, the body fluid component measuring apparatus 10 includes a case 100, a disposable kit 200, a supply member 300, a push member 400, a detection member 500, and a display. The member 600 is included.

The case 100 has a storage space 110 formed therein, and the storage space 110 is provided with a disposable kit 200, a supply member, a push member detection member, and a display member, respectively.

A circular opening 114 is formed in one side wall 112 of the case 100. One end of the penetrating member 220, which is a microcapillary tube, to be described later, protrudes through the opening 114. The ball 310 serving as the supply member 300 is installed on the upper wall 116 of the case 100, and the display member 600 is installed next to the ball 310. The display member 600 is composed of, for example, a liquid crystal display device. For example, the display member 600 may display various kinds of information such as power on / off, measured value, measurement date and time, error display, and the like.

Under the display member 600, a control member 700 composed of a microcomputer is installed. This control member 700 controls whether or not blood has been collected and controls all operations of the body fluid component measuring apparatus 10. In addition, the control member 700 has a built-in calculation unit for calculating glucose in the blood based on the signal from the detection member 500.

The detection member 500 is installed at the bottom of the case 100. The detection member 500 optically detects that the blood is supplied to the reagent paper 210 to be described later, and optically measures the glucose component in the blood supplied to the reagent paper 210. Below the 310, it is near the bottom where the reagent paper 210 is placed. The detection member 500 has a function of measuring the amount of glucose in the blood supplied to the reagent paper 210.

Referring to FIGS. 3 and 4, the disposable kit 200 includes a reagent paper 210 and a penetrating member 220 positioned on the reagent paper 210. The penetrating member 200 is adhesively fixed to the elastic support 230, and both ends of the sheet-shaped elastic support 230 are adhesively fixed to the reagent paper 210. Disposable kid 200 is installed to replace the inner space of the case 100.

The reagent paper 210 and the detection member 500 are not limited to any particular form. For example, if the detecting member 500 is an optical measuring means for detecting the color change in the reagent paper 210 as in the case of measuring glucose in the body fluid, the reagent paper 210 may include glucose oxidase, peroxydiaze, and Colorogenic agents resulting from drying may be injected. The reagent paper 210 is preferably made of a non-woven porous membrane, woven fabric, elongated sheet or material such as polyester, polyamide, polyolefin, polysulfone, cellulose, and the like. Since the reagent paper 210 is impregnated with body fluids as well as various reagents, the reagent paper 210 is preferably formed of a hydrophilic material or treated to provide hydrophilicity, and may be a single layer sheet or a multilayer sheet. .

The penetrating member 220 may extract and retain body fluid by capillary action while penetrating the epidermis of the skin. The penetrating member 220 is made of a fine capillary tube of a size capable of extracting body fluid through a capillary phenomenon. The penetrating member 220 includes an inlet 222 through which the body fluid is sucked, a passage 224 through which the body fluid sucked through the inlet 222 is received, and an outlet 226 through which air in the passage 224 can escape. Have The penetrating member 220 has an outer diameter of 0.5 mm to 0.05 mm and consists of a fine tube having an inner diameter of 0.4 mm to 0.04 mm. One end of the penetrating member 220 (portion penetrating the epidermis of the skin) is preferably formed to be sufficiently sharp and inclined so as to easily penetrate the skin. The penetrating member 220 may be one of cylindrical or rectangular tubes, but for ease of manufacture, the penetrating member 220 is preferably a cylindrical tube.

In particular, the penetrating member 220 may be made of a suitable material that can be broken by the ball 310 of the supply member 300. Typically, plastics, glass, ceramics or balls 310 may be made of a variety of other materials that may be broken by 310. The penetrating member 220 may be made of a transparent material such as glass, plastic or other similar plastic. In some embodiments, it is desirable to provide a see-through window that makes the penetrating member 220 transparent or allows a user to observe the progress of bodily fluid being sucked into the penetrating member 220.

The elastic support 230 receives the force from the push member 400 to move the penetrating member 220 to a forward position for body fluid extraction. When the user presses the push member 400, the elastic support 230 is moved in the forward direction by the push member 400, so that the through member 220 waiting at the retracted position is moved to the movement of the elastic support 230. Is moved to the forward position for body fluid extraction. The penetrating member 230 thus moved is inserted into the skin while one end protrudes through the opening 114 of the case 100. When the user releases the force applied to the push member 400, the penetrating member 220 is returned to the retracted position by the elastic restoring force of the elastic support 230.

Referring to FIGS. 2 and 3, the push member 400 is a retracted position for returning the penetrating member 220 to a forward position (see FIG. 3) and body member extracting the penetrating member 220 to its original position. (See Fig. 2). The push member 400 is installed on one side wall of the case 100 to move back and forth in the longitudinal direction of the through member 220. One end of the push member 400 is exposed to the outside of the case 100 so that the user can press, the other end is in contact with the elastic support 230.

5A and 5B, the supply member 300 is for supplying the bodily fluid extracted by the penetrating member 220 to the reagent paper 210, and the supply member 300 is provided in the case 100. A ball 310 is installed to be movable up and down at an upper portion. The ball 310 is to break the penetrating member 220 so that the body fluid contained in the passage 224 of the microcapillary tube, which is the penetrating member 220, falls into the reagent paper 210, and the ball 310 is the penetrating member 220. The sharp part 312 so that it is easily broken, and includes a spring 320 so that the user is released when the force is released.

Looking at the blood glucose test process using the body fluid composition measuring device configured as described above are as follows.

5A and 5B are views illustrating a process of extracting blood from a penetrating member at a forward position and providing a extracted blood to reagent paper.

First, the opening 114 of the case 100 is positioned on a body part such as a finger to extract blood. At this time, one side wall 112 having the opening 114 of the case 100 comes into contact with the skin. In this state, when the user applies the force to the push member 400 in the forward direction, the penetrating member 220 is moved from the retracted position to the forward position. In the forward position, the penetrating member 220 penetrates through the skin tissue, and blood is sucked into the passage 224 through the inlet 222 of the penetrating member 220 by capillary action (see FIG. 5A). After a sufficient amount of blood is received in the passage 224 of the penetrating member 220, when the user releases the force applied to the push member 400, the penetrating member 220 is formed by the elastic restoring force of the elastic support 230. It is returned to the retracted position. As described above, in the present invention, a lancing process of wounding the skin and a sampling process of squeezing blood from the wound of the skin by the user are performed continuously and in a short time.

As shown in FIG. 5B, the blood extracted by the penetrating member 220 is supplied to the reagent paper 210. In the blood supply to the reagent paper 210, when the user presses the ball 310 downward, the ball 310 breaks the penetrating member 220 and the blood in the passage 224 of the penetrating member 220. This reagent paper 210 is provided. In the present exemplary embodiment, the user manipulates the ball 310 manually, but for convenience of operation, the driving device may be added so that the ball 310 automatically breaks the penetrating member 220. When the blood is supplied to the reagent paper 210, the glucose component and the amount of blood in the blood supplied from the detection member 500 to the reagent paper 210 are optically measured. The measured result is displayed on the display member 600.

As described above, in the present invention, a lancing process for wounding the skin, a blood extraction process, and a blood glucose measurement by providing the obtained blood as a reagent paper are continuously and rapidly performed.

In the above-described embodiment, the blood is taken as a representative body fluid to be collected. However, in the present invention, the body fluid to be collected is not limited to this and may be, for example, sweat, lymphatic fluid, and sap.

In the above embodiment, glucose (blood sugar level) is represented as a component for measurement purposes, but the components for measurement in the present invention are not limited thereto, and for example, protein, cholesterol, uric acid, creatinine, alcohol, sodium, and the like. Inorganic ion etc. may be sufficient.

The apparatus for measuring bodily fluid components of the present invention may be modified in the following alternative embodiments.

6A and 6B illustrate an example in which a disposable kit 200a including only the reagent paper 210 and the penetrating member 220 is employed. 6A and 6B, the penetrating member 220 is fixed to the rear end of the penetrating member 800, and the holder 800 is connected to the push member 400. The holder 800 may be included in the disposable kit 200a, but the holder 800 may be provided as a component that is mounted in the inner space of the case 100. The holder 800 is formed with an exhaust port 810 in communication with the outlet 226 of the through member 220. The push member 400 moves the holder 800 in the forward direction, and the penetrating member 220 fitted to the holder 800 is moved to the forward position. The return of the penetrating member 220 to the retracted position is performed by the spring 420 of the push member 400.

In the disposable kit 200a illustrated in FIGS. 6A and 6B, the penetrating member 220 may be attached to the reagent paper 210 by a tape, and the reagent paper 210 may be mixed with the penetrating member 220 before and after. Can be moved. The disposable kit 200a having such a structure has an advantage of being easier to manufacture than the disposable kit 200 shown in FIG. 1.

In the above embodiment, the detection member measures the amount of the predetermined component, but in the present invention, the measuring means may measure the amount of the predetermined component, or may measure the amount and the property of the predetermined component.

Moreover, although the said embodiment uses the means which optically detects the collection | collection of blood as a detection member, it is not limited to this in this invention, In addition, you may use other means, for example, an electrical detection.

In the present invention, in the case of using a blood sampling detection means for optically detecting the collection of blood, the color intensity of the reagent paper colored by the reaction of the components and reagents in the blood as described above is optically measured and converted into measured values, It is not limited to display, For example, the electrical potential change which arises according to the quantity of the component in a sample may be measured electrically, and converted into a measured value and displayed.

In the above, the configuration and operation of the bodily fluid component measuring apparatus according to the present invention has been shown in accordance with the above description and drawings, but this is just described, for example, and various changes and modifications can be made without departing from the technical spirit of the present invention. Of course.

In the present invention, it is possible to reliably collect a sufficient amount of blood necessary for measurement in a short time, and at the same time, it is possible to accurately and reliably measure the blood glucose level (amount of a predetermined component in the blood).

In addition, the present invention is easy to perform the blood glucose measurement in a short time because the lancing process to injure the skin, the blood extraction process and the blood glucose measurement by providing the obtained blood to the reagent paper continuously and quickly can do.

In addition, the present invention can automatically extract the body fluid from the skin by using a capillary phenomenon.

In addition, the present invention, because the penetrating member is made of a small capillary tube can be collected and examined without causing excessive pain.

Claims (12)

delete In a device for extracting and measuring a bodily fluid: Reagent paper; Located in the upper portion of the reagent paper, the penetrating member for penetrating the skin to extract the body fluid to the capillary phenomenon; And A supply member for supplying the bodily fluid extracted by the penetrating member to the reagent paper; The supply member And a body for breaking the penetrating member such that the body fluid extracted by the penetrating member falls into the reagent paper. The method of claim 2, And the penetrating member is fixed to the reagent paper by an elastic support such that the penetrating member and the reagent paper are formed of one kit. The method of claim 2, The through member is Body fluid component measuring device, characterized in that consisting of a fine capillary tube sized to extract body fluid through capillary action. The method of claim 4, wherein The microcapillary And an inlet through which the body fluid is sucked by the capillary phenomenon, a passage through which the body fluid sucked through the inlet is accommodated, and an outlet through which air in the passage can escape. The method according to claim 4 or 5, The outer diameter of the fine capillary is 0.5mm ~ 0.05mm, the inner diameter of the body fluid component measuring device, characterized in that it has a 0.4mm-0.04mm. The method of claim 2, The device is And a push member for moving the penetrating member so that one end of the penetrating member penetrates the skin. The method of claim 2, The device is And a push member for moving the penetrating member to a forward position for extracting body fluid and to a retracted position for returning the penetrating member from which body fluid is extracted to its original position. The method of claim 2, The device is And a detection member for detecting a component of the bodily fluid provided to the reagent paper, and a display member for displaying the result detected by the detection member. In a device for extracting and measuring a bodily fluid: Reagent paper; Located in the upper portion of the reagent paper, the penetrating member for penetrating the skin to extract the body fluid to the capillary phenomenon; A push member for moving the penetrating member to a forward position for extracting body fluid and to a retracted position for returning the penetrating member from which body fluid is extracted to its original position; A pestle for breaking the penetrating member such that the body fluid extracted by the penetrating member falls into the reagent paper; A detection member for detecting a component of a body fluid provided to the reagent paper; And a display member for displaying the result detected by the detection member. The method of claim 10, And the penetrating member is fixed to the reagent paper by an elastic support such that the penetrating member and the reagent paper are formed of one kit. The method of claim 10, The through member is And a microcapillary tube having an inlet through which the body fluid is sucked by the capillary phenomenon, a passage through which the body fluid sucked through the inlet is accommodated, and an outlet through which air in the passage can escape.

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