KR100745046B1 - Polymer injectable detachable coil - Google Patents

Polymer injectable detachable coil Download PDF

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KR100745046B1
KR100745046B1 KR1020060072497A KR20060072497A KR100745046B1 KR 100745046 B1 KR100745046 B1 KR 100745046B1 KR 1020060072497 A KR1020060072497 A KR 1020060072497A KR 20060072497 A KR20060072497 A KR 20060072497A KR 100745046 B1 KR100745046 B1 KR 100745046B1
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coil
polymer
platinum
characterized
detachable embolic
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KR1020060072497A
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Korean (ko)
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성 권 강
성 현 김
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주식회사 에스앤지바이오텍
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12099Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
    • A61B17/12109Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel
    • A61B17/12113Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel within an aneurysm
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12131Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
    • A61B17/1214Coils or wires
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B17/12131Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
    • A61B17/12181Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device formed by fluidized, gelatinous or cellular remodelable materials, e.g. embolic liquids, foams or extracellular matrices
    • A61B17/12186Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device formed by fluidized, gelatinous or cellular remodelable materials, e.g. embolic liquids, foams or extracellular matrices liquid materials adapted to be injected
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/12Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
    • A61B17/12022Occluding by internal devices, e.g. balloons or releasable wires
    • A61B2017/1205Introduction devices
    • A61B2017/12054Details concerning the detachment of the occluding device from the introduction device
    • A61B2017/12063Details concerning the detachment of the occluding device from the introduction device electrolytically detachable

Abstract

A polymer injectable separation type embolization coil is provided to perform embolization of cerebral aneurysm even with a small number of coil by injecting liquid polymer into a hollow of the coil through a hollow of a hypo tube by connecting a separable coil with a hypo tube. A polymer injectable separation type embolization coil includes: an embolization platinum coil part(1) that a polymer coating layer(1a) is formed on the outer periphery of a platinum coil(1b) with a hollow; a coil pusher(2) that an insulation coating layer(2b) is formed on the outer periphery of a hypo tube(2a) with a hollow; a connection part(3) having a polymer injecting channel, and connecting the embolization platinum coil and coil pusher, and separating them by electrolysis; and a power supply device(4) for supplying a power for electrolyzing the connection part.

Description

폴리머 주입이 가능한 분리형 색전코일 {Polymer injectable detachable coil} The detachable embolic coils polymer injectable {Polymer injectable detachable coil}

도 1은 액상 폴리머를 주입하지 않은 상태를 나타내는 본 발명에 따른 분리형 색전코일의 단면 개략도. 1 is a schematic cross-section of detachable embolic coils in accordance with the present invention showing a state in which no injection of a liquid polymer.

도 2는 액상 폴리머를 주입한 상태를 나타내는 본 발명에 따른 분리형 색전 코일의 단면 대략도. Figure 2 is a cross-section substantially of the detachable embolic coil according to the present invention showing a state in which injection of liquid polymer.

본 발명은 뇌 동맥류 치료에 사용되는 폴리머 주입이 가능한 분리형 색전코일에 관한 것이다. The present invention relates to a detachable embolic coil is injected into the polymer used for aneurysms treatable. 뇌동맥이 비정상적으로 부풀어 생기는 뇌 동맥류는 정상적인 혈관 벽에 비해 파열의 위험이 높으며 파열이 되면 지주막하 출혈을 비롯한 심각한 뇌출혈을 일으킨다. The unusually cerebral aneurysms occur when the swollen by the high risk of rupture rupture compared to the normal vessel wall causing severe hemorrhage, including subarachnoid hemorrhage. 뇌동맥류의 치료로 개두술을 통한 동맥류 클립과 더불어 혈관을 통하여 동맥류에 접근하여 분리형 색전코일을 동맥류 내에 삽입하여 혈류에서 분리시키는 방법으로 재출혈을 방지하는 치료가 많이 시행되고 있다. With aneurysm clips through the craniotomy to treat the cerebral aneurysm access to the aneurysm through a blood vessel by inserting a detachable embolic coils within the aneurysm, and has been implemented many treatment to prevent re-bleeding in a manner to separate from the blood stream.

뇌 동맥류의 1차 치료목표는 동맥류 파열이나 재 파열에 의한 재 출혈을 방 지하는 것으로 전통적인 치료법은 개두술에 의한 동맥류의 경부 클립이다. The primary treatment goal of brain aneurysms traditional treatments to the room occupied by the hemorrhage due to aneurysm rupture or re-rupture of the aneurysm due to a neck clip craniotomy. 두개골을 열고 동맥류가 있는 혈관을 찾아 금속으로 만들어진 클립으로 동맥류의 목 부분을 잡아 혈류가 동맥류 내로 들어오지 못하도록 하는 것이다. Open the skull with a clip to find a vein in the neck of the aneurysm Metal catch of the aneurysm to prevent blood from entering into the aneurysm.

20년전 분리형 색전코일이 개발되면서 혈관내로 가는 카테터를 삽입 동맥류에 카테터의 선단을 넣어놓고 카테터를 통해 분리형 색전코일을 동맥류 내에 충분한 양을 삽입하면 동맥류는 코일에 의해 채워지고 더 이상 혈류가 동맥류 내로 들어오지 못하게 함으로써 동맥류의 재파열에 의한 재출혈을 방지하는 치료법이 가능해 졌다. It developed a detachable embolic coil 20 years ago by inserting a sufficient amount of a detachable embolic coil placed into the distal end of the catheter a thin catheter into the blood vessel to the insertion aneurysm through a catheter into the aneurysm, the aneurysm is filled by the coil come into more or more flow aneurysms let this therapy to prevent rebleeding by re-rupture of the aneurysm was possible by.

분리형 색전코일의 장점은 필요시에만 코일을 코일 푸셔로부터 분리할 수 있기 때문에 필요에 따라 삽입, 제거를 반복함으로써 동맥류의 모양에 맞추어 모동맥의 혈류장애 없이 동맥류를 색전할 수 있다는 것이다. The advantage of the detachable embolic coil is that it can be inserted into the aneurysm embolization if necessary, by repeating the removal according to the shape of the aneurysm without the blood flow disorder of the parent artery it is possible to separate from the coil pusher to the coil only when necessary.

그러나 동맥류 내에 코일을 삽입하는 치료는 그 자체로 동맥류 파열의 위험이 있으며 백금으로 만들어진 코일을 사용하여 동맥류를 완전히 채우는 것은 이론적으로 불가능하여 부피의 비율로 동맥류 부피의 50~60% 이상을 채우기 어렵다. However, the treatment of inserting a coil within the aneurysm that there is a risk of self-aneurysm rupture is using coils made of platinum to fill the aneurysm completely difficult to fill at least 50% to 60% of the aneurysm volume as a percentage of the volume theoretically impossible.

이런 이유로 코일에 의한 동맥류 치료 후에도 동맥류 내로 다시 혈류가 통하는 등 재발의 가능성이 높아 처음 치료 시에 가능한 한 많은 양의 코일을 동맥류 내에 삽입하는 것이 좋은 치료법이다. It is a good remedy for inserting this reason, a large amount of coil after aneurysm treatment by the coil increases the likelihood of a recurrence of such back flow into the aneurysm through the available during the first treatment within the aneurysm. 그러나 동맥류 내에 가능한 한 많은 양의 코일을 채우는 것은 동맥류의 파열, 과다삽입된 코일에 의한 모동맥의 폐색 등의 심각한 합병증의 위험도를 높여 치료를 어렵게 하고 있다. However, filling and a large amount of coil within the aneurysm, it can increase the risk of serious complications such as occlusion of the parent artery due to the rupture or excessive insertion of the coil makes it difficult to treat aneurysms. 이러한 현상은 특히 동맥류의 입구가 넓은 경우, 동맥류의 크기가 작은 경우 특히 문제가 되고 있다. This phenomenon has been a particular problem, especially if the entrance of the aneurysm, a large, if the size of the small aneurysms.

이러한 코일 색전술의 불완전성 때문에 최근에는 트리셀룰로오스 아세테이트(tricellulose acetate) 등과 같이 혈류와 반응하여 중합반응을 일으켜 고체화되는 액상 폴리머를 뇌동맥류 내에 주입하는 방법이 시도되고 있으나 액상의 폴리머가 흐름이 빠른 동맥 혈류를 따라 원위부 혈관으로 날아가 혈관을 폐색시키는 심각한 합병증이 있어 아직까지는 임상에서 사용하기 어렵다. Because of imperfections such coil embolization Recently tree cellulose acetate (tricellulose acetate) blood flow with the reaction method of injecting a liquid polymer that solidifies causing a polymerization reaction in the cerebral aneurysm is tried to but fast that the liquid polymer flow of arterial blood flow, such as There is a serious complication of blood vessels in the distal vascular obstruction fly along the still difficult to use in clinical away.

본 발명은 이와 같은 종래의 문제점들을 해결하기 위해서 기존의 분리형 색전코일에 폴리머 코팅을 한 후 코일의 내강으로 액상 폴리머를 주입할 수 있도록 하여 기존의 색전코일로는 기대하기 어려운 뇌동맥류의 완전색전을 할 수 있게 하고 소수의 코일로도 뇌동맥류를 완전히 색전할 수 있도록 하여 안전하고 용이하게 뇌동맥류를 치료할 수 있도록 하는 것이다. The invention this After the polymer coating in conventional detachable embolic coil in order to solve the conventional problems and to inject liquid polymer into the lumen of the coil to complete occlusion of the difficult to expect aneurysms in conventional embolization coil and it will be able to help treat aneurysms safe and easy by allowing you to complete the aneurysm embolization as a small number of coils.

본 발명은 분리형 색전코일을 하이포튜브와 연결함으로써 하이포튜브의 내강을 통해 코일의 내강으로 액상 폴리머를 주입할 수 있도록 하여 소수의 코일로도 뇌동맥류의 완전색전을 할 수 있는 폴리머 주입가능 분리형 색전코일을 제공하고자 한다. The invention detachable embolic coil to be a polymer injection to a full occlusion of Figure aneurysms with a small number of coils to inject a liquid polymer into the lumen of the coil through a lumen of the hypo-tube by connecting with the hypo-tube detachable embolic coil It intends to provide.

또한, 본 발명은 분리형 색전코일의 코일파트에 폴리머를 얇게 코팅하여 주입되는 액상폴리머의 양에 따라 늘어나고 동맥의 혈류를 따라 주입된 액상 폴리머가 날아가지 않도록 하여 안전하고 효과적인 폴리머 주입가능 분리형 색전코일을 제공하고자 한다. Further, the present invention is detachable embolic coil of the coil part to a safe and effective polymer injectable detachable embolic coil prevent the liquid polymer is flying injected along the blood flow in the artery increases with the amount of the liquid polymer is injected with a thin coating of the polymer in It intends to provide.

이와 같은 과제들을 달성하기 위한 본 발명의 폴리머 주입이 가능한 분리형 색전코일은 [ⅰ] 내강을 갖는 백금코일(1b)의 외주면에 폴리머 코팅층(1a)이 형성되어 있는 색전용 백금코일부(1), [ⅱ] 내강을 갖는 하이포 튜브(2a)의 외주면에 절연 코팅층(2b)이 형성되어 있는 코일푸셔(2), [ⅲ] 폴리머 주입용 채널을 구비하고, 상기 색전용 백금코일과 코일푸셔를 연결해 주고 있다가 전기분해에 의해 상기 색전용 백금코일과 코일푸셔를 분리시켜 주는 연결부(3) 및 [ⅳ] 상기 연결부(3)를 전기분해시키기 위한 전력을 공급하는 전력공급장치(4)로 구성됨을 특징으로 한다. The detachable embolic coils can polymer injection of the present invention for achieving the tasks of the [ⅰ] color only platinum coil with the outer circumferential surface of the polymer coating layer (1a) is formed on the platinum coil (1b) having a cavity (1), [ⅱ] isolated in the outer circumferential surface of the hypo-tube (2a) having an inner cavity the coating layer (2b) is provided with a coil pusher (2), [ⅲ] polymer injected for a channel is formed, and connect the color-only platinum coil and coil pusher a configured to have a connecting portion 3 and the [ⅳ] that was by electrolysis separating the color-only platinum coil and coil pusher to give the connecting portion 3 to the power supply device 4 for supplying the electric power for electrolysis It characterized.

이하, 첨부한 도면 등을 통하여 본 발명을 상세하게 설명한다. The detailed description of the present invention throughout the accompanying drawings and the like.

먼저, 본 발명은 도 1 및 도 2에 도시된 바와 같이 백금코일(1b)의 외주면에 폴리머 코팅층(1a)이 형성되어 있는 색전용 백금코일부(1), 하이포튜브(2a)의 외주면에 절연코팅층(2a)이 되어 있는 코일 푸셔(2), 코일과 코일 푸셔를 연결하며 전기분해에 의해 이들을 분리시키며 폴리머 주입용 채널이 있는 연결부(3), 상기 연결부(3)를 전기분해시키기 위한 전력공급장치(4)로 구성된다. First, the present invention is isolated to the outer peripheral surface of FIG. 1 and the platinum coil (1b), the hypo-tube (2a) colors only platinum coil with the polymer coating layer (1a) on the outer peripheral surface is formed (1), as shown in Figure 2 connecting the coil pusher (2), coil and coil pusher, which is a coating layer (2a) and the connecting portion isolates them by electrolysis with a channel for polymer injection (3), the power supply for the electrolysis to the connecting part (3) consists of a device (4). 그로인해 본 발명은 동맥류내에 삽입된 코일의 내강으로 액상 폴리머를 주입할 수 있어 소수의 코일로 동맥류의 완전색전을 할 수 있다. The present invention, thus producing the liquid polymer can be injected into the lumen of the coil inserted into the aneurysm can be a full occlusion of the aneurysm in a small number of coils.

도 1은 액상 폴리머를 주입하지 않은 상태를 나타내는 본 발명에 따른 분리형 색전코일의 단면개략도 이고, 도 2는 액상 폴리머를 주입한 상태를 나타내는 본 발명에 따른 분리형 색전코일의 단면 개략도이다. 1 is a cross-sectional schematic view of a detachable embolic coil according to the present invention showing a state in which no injection of liquid polymer, Figure 2 is a cross-sectional schematic view of a detachable embolic coil according to the present invention showing a state in which injection of liquid polymer.

상기의 색전용 백금코일부(1)는 액상 폴리머가 주입되는 내강을 갖고, 상기 내강내로 주입되는 액상 폴리머(1c)가 혈류를 따라 날아가지 않도록 백금코일(1b)의 외주면에 얇은 폴리머 코팅층(1a)이 형성되어 있으며, 액상 폴리머(1c)가 주입되면 백금코일에 코팅된 얇은 폴리머 막이 백금코일(1b)에서 떨어서 액상 폴리머(1c)의 양에 따라 부풀어 오른다. Color only platinum coil (1) in the liquid polymer has a lumen that is injected, the liquid polymer (1c) to be injected into the lumen of a thin polymer coating layer on the outer peripheral surface of the platinum coil (1b) prevent flying the bloodstream (1a ) this is formed, when the liquid polymer (1c) is injected into a thin film polymer coating on the platinum coil rises in accordance with the amount of bulging tteoleoseo liquid polymer (1c) on the platinum coil (1b). 또한 액상 폴리머(1c)가 백금코일 내강으로부터 균일하게 새어 나올 수 있도록 미세한 구멍이 백금코일(1b) 전장에 걸쳐 뚫려 있다. In addition, there are small holes so that the liquid polymer (1c) may appear uniformly leaking from the platinum coil lumen bored over the platinum coil (1b) total length.

다음으로, 코일 푸셔(2)는 하이포튜브(2a)로 만들어져 있어 하이포 튜브의 내강을 통하여 액상 폴리머(1c)를 주입할 수 있으며, 상기 하이포튜브(2a)의 외주면에는 절연 코팅층(2b)이 형성되어 있다. Next, the coil pusher (2) has an insulating coating layer (2b), the outer peripheral surface of the hypo-tube (2a) to, it can be injected into the liquid polymer (1c) via the lumen of the hypo-tube made of said hypo-tube (2a) is formed It is. 코일 푸셔(2)의 근위부 끝에는 표지자(5)와 주사기 등을 연결할 수 있는 허브(6)가 부착되어 있어 이를 통하여 액상 폴리머(1c)를 주입할 수 있다. Coil pusher (2) proximal end marker (5) and the syringe, such as to connect the hub (6) there is attached, which can be injected in the liquid polymer (1c) through which.

액상 폴리머로는 트리셀룰로오스 아세테이트(Tricellulose acetate) 등이 사용될 수 있다. A liquid polymer may be used, such as tree cellulose acetate (Tricellulose acetate).

다음으로, 코일과 코일 푸셔의 연결부(3)는 절연 폴리머 튜브로 만들어져 있어 백금코일 분리를 위해 인가되는 전류가 백금코일로 통하지 않도록 한다. Next, the connecting portion 3 of the coil and the coil pusher is so impervious to the platinum coil current that is applied to the separation of platinum coil are made of an insulating polymeric tube. 또한 백금코일부(1)와 하이포튜브(2a)를 단단히 연결하여 액상 폴리머 주입시 압력에 의해 분리되지 않는다. In addition, platinum nose firmly connected to a part (1) and the hypo-tube (2a) and not separated by a pressure when a liquid polymer injection. 상기 연결부(3)는 전기분해 가능한 폴리머 튜브이다. The connector part 3 is a electrolytic polymer tube possible.

본 발명은 폴리머가 코팅된 색전용 백금코일부(1)에 내강이 있는 금속 튜브인 하이포튜부(2a)로 만들어진 코일푸셔(2)를 연결함으로써 액상 폴리머를 주입할 수 있도록 하였으며, 전기분해를 통하여 코일과 푸셔 사이를 전기분해를 통해 분리 할 수 있도록 하였다. The invention was to inject liquid polymer by connecting the coil pusher (2) made of a hypo-tyubu (2a) colors only platinum polymeric coating nose metal in the cavity in the part (1) tubes, through the electrolysis between the pusher and coil it was to be separated through electrolysis.

동맥류 내에 분리형 백금코일부(1)을 삽입한 후 액상 폴리머를 하이포튜브(2a) 내강을 통해 주입하여 백금코일의 내강을 채우고 백금코일 루프 사이로 새 나오는 액상 폴리머가 도 2에 도시된 바와 같이 미리 백금코일 외주면에 코팅 있는 폴리머 주머니 내로 주입되어 동맥류 내에 삽입되어 있는 코일의 부피를 늘이고 액체인 액상 폴리머가 백금코일 사이의 공간을 완전히 채워 한 두개의 백금코일로 동맥류의 완전 색전을 얻을 수 있도록 하였다. After inserting the detachable platinum coil (1) within the aneurysm to inject liquid polymer through a hypo tube (2a) cavity fill the cavity of the platinum coil that liquid polymer out new between platinum coil loop pre-platinum, as shown in FIG. is injected into the coating polymer in the pocket coil to the outer circumferential surface was of two platinum coils, a liquid polymer extends the volume of the coil which is inserted into the aneurysm, the liquid is completely filled in the space between the platinum coil to obtain full occlusion of the aneurysm.

백금코일의 외주면에 미리 코팅되어 있는 폴리머에 의해 주입된 액상 폴리머의 움직임이 제한되며 동맥류 내에 삽입되어 있는 백금코일이 프레임 역할을 하여 주입된 액상 폴리머가 동맥혈류를 타고 원위부 동맥으로 날라가는 것을 방지할 수 있으며, 백금코일 프레임을 따라 액상폴리머가 주입됨으로써 동맥류만 선택적으로 색전할 수 있는 장점이 있다. The movement of the liquid polymer injection by a polymer which is pre-coated on the outer peripheral surface of the platinum coil limits and by the frame acts platinum coil, which is inserted into the aneurysm, the injected liquid polymer is riding on arterial blood flow to be prevented from going blown into distal arteries number, and a liquid polymer injected along the platinum coil frame being can advantageously embolization selectively only aneurysm.

또한 한 두 개의 소수의 백금코일로 뇌동맥류의 완전색전을 기대할 수 있기 때문에 많은 수의 백금코일을 삽입해야 하는 거대 동맥류나 여러 개의 코일을 삽입하기 어려운 작은 동맥류를 안전하게 색전할 수 있는 장점이 있다. There are also a large number of giant aneurysms or benefits to embolization difficult small aneurysms to insert multiple coil securely to the need to insert platinum coils because you expect to complete occlusion of the aneurysm with a two decimal platinum coils.

본 발명은 뇌동맥류의 치료에 사용되는 분리형 색전코일의 내강에 액상 폴리머를 동맥류의 크기와 모양에 맞게 주입하여 소수의 코일로 동맥류를 완전히 색전할 수 있어 뇌동맥류의 치료에 관련된 합병증의 감소와 재발을 줄일 수 있다. The present invention reduces the recurrence of complications associated with the treatment of aneurysms aneurysms there the liquid polymer can be injected to the size and shape of the aneurysm to completely embolic the aneurysm with the small number of coils in the cavity of the detachable embolic coils used for treating to be reduced.

Claims (6)

  1. [ⅰ] 내강을 갖는 백금코일(1b)의 외주면에 폴리머 코팅층(1a)이 형성되어 있는 색전용 백금코일부(1), [ⅱ] 내강을 갖는 하이포 튜브(2a)의 외주면에 절연 코팅층(2b)이 형성되어 있는 코일푸셔(2), [ⅲ] 폴리머 주입용 채널을 구비하고, 상기 색전용 백금코일과 코일푸셔를 연결해 주고 있다가 전기분해에 의해 상기 색전용 백금코일과 코일푸셔를 분리시켜 주는 연결부(3) 및 [ⅳ] 상기 연결부(3)를 전기분해시키기 위한 전력을 공급하는 전력공급장치(4)로 구성됨을 특징으로 하는 폴리머 주입이 간으한 분리형 색전코일. [Ⅰ] coating layer insulation on the outer circumferential surface of the color-only platinum coil with the outer circumferential surface of the polymer coating layer (1a) is formed on the platinum coil (1b) having a cavity (1), [ⅱ] hypo tube (2a) having an inner cavity (2b ) is a coil pusher (2) which form, [ⅲ] polymer injection and a for the channel, by the by electrolysis giving connect the color-only platinum coil and coil pusher separating the color-only platinum coil and coil pusher that the connection (3) and [ⅳ] the connection part 3, a detachable embolic coil by injecting a polymer, characterized by consisting of a power supply device 4 for supplying power for electrolyzing ganeu.
  2. 1항에 있어서, 코일퓨셔(2)의 후단부에 표지자(5)와 허브(6)가 차례로 설치되어 있는 것을 특징으로 하는 폴리머 주입이 가능한 분리형 색전코일. According to one of the preceding claims, Fuchsia coil (2) to the end marker (5) and the hub (6) is installed in order polymer injection is possible detachable embolic coil, characterized in that after the.
  3. 1항에 있어서, 백금코일(1b)에는 전장에 걸쳐 미세한 구멍이 형성되어 있는 것을 특징으로 하는 폴리머 주입이 가능한 분리형 색전코일. According to claim 1, wherein the platinum coil (1b), the fine holes is formed over the entire length polymer injection is possible detachable embolic coil, characterized in that.
  4. 1항에 있어서, 연결부(3)는 절연 폴리머 튜브인 것을 특징으로 하는 폴리머 주입이 가능한 분리형 색전코일. According to item 1, wherein the connecting portion (3) is detachable embolic coil capable of injecting the polymer, it characterized in that the insulating polymeric tube.
  5. 1항에 있어서, 백금코일(1b)의 외주면에 형성된 폴리머 코팅층(1a)은 백금코일 내강내로 액상 폴리머(1c)가 주입되면 백금코일(1b)로부터 분리되면서 주입된 액상 폴리머(1c)에 의해 주머니 모양으로 부풀어 오르는 것을 특징으로 하는 폴리머 주입이 가능한 분리형 색전코일. According to claim 1, wherein the pocket by a polymer coating layer (1a) is a platinum coil when the liquid polymer (1c) injected into the lumen of the platinum coil the liquid polymer (1c) injected as separated from the (1b) formed on the outer peripheral surface of the platinum coil (1b) detachable embolic coil is injected into the polymer, characterized in that a bulging shape as possible.
  6. 1항에 있어서, 연결부(3)는 전기분해 가능한 폴리머 튜브인 것을 특징으로 하는 폴리머 주입이 가능한 분리형 색전코일. According to item 1, wherein the connecting portion (3) is detachable embolic coil capable of injecting the polymer, it characterized in that the electrolytic polymer tube possible.
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US5702361A (en) * 1996-01-31 1997-12-30 Micro Therapeutics, Inc. Method for embolizing blood vessels
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US6923996B2 (en) * 2003-05-06 2005-08-02 Scimed Life Systems, Inc. Processes for producing polymer coatings for release of therapeutic agent

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