JPWO2023283624A5 - - Google Patents

Info

Publication number
JPWO2023283624A5
JPWO2023283624A5 JP2024500492A JP2024500492A JPWO2023283624A5 JP WO2023283624 A5 JPWO2023283624 A5 JP WO2023283624A5 JP 2024500492 A JP2024500492 A JP 2024500492A JP 2024500492 A JP2024500492 A JP 2024500492A JP WO2023283624 A5 JPWO2023283624 A5 JP WO2023283624A5
Authority
JP
Japan
Prior art keywords
seq
oligonucleotide
optionally
complex
sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024500492A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024525613A (ja
JP2024525613A5 (https=
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/073541 external-priority patent/WO2023283624A2/en
Publication of JP2024525613A publication Critical patent/JP2024525613A/ja
Publication of JPWO2023283624A5 publication Critical patent/JPWO2023283624A5/ja
Publication of JP2024525613A5 publication Critical patent/JP2024525613A5/ja
Pending legal-status Critical Current

Links

JP2024500492A 2021-07-09 2022-07-08 筋標的化複合体およびジストロフィノパチーを処置するためのその使用 Pending JP2024525613A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163220016P 2021-07-09 2021-07-09
US63/220,016 2021-07-09
US202263316466P 2022-03-04 2022-03-04
US63/316,466 2022-03-04
PCT/US2022/073541 WO2023283624A2 (en) 2021-07-09 2022-07-08 Muscle targeting complexes and uses thereof for treating dystrophinopathies

Publications (3)

Publication Number Publication Date
JP2024525613A JP2024525613A (ja) 2024-07-12
JPWO2023283624A5 true JPWO2023283624A5 (https=) 2025-07-17
JP2024525613A5 JP2024525613A5 (https=) 2025-07-17

Family

ID=84802101

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024500492A Pending JP2024525613A (ja) 2021-07-09 2022-07-08 筋標的化複合体およびジストロフィノパチーを処置するためのその使用

Country Status (9)

Country Link
US (1) US20240368296A1 (https=)
EP (1) EP4366741A4 (https=)
JP (1) JP2024525613A (https=)
KR (1) KR20240035824A (https=)
AU (1) AU2022309238A1 (https=)
CA (1) CA3226367A1 (https=)
IL (1) IL309912A (https=)
MX (1) MX2024000492A (https=)
WO (1) WO2023283624A2 (https=)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11168141B2 (en) 2018-08-02 2021-11-09 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating dystrophinopathies
US11911484B2 (en) 2018-08-02 2024-02-27 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating myotonic dystrophy
US12097263B2 (en) 2018-08-02 2024-09-24 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating myotonic dystrophy
US20220193250A1 (en) 2018-08-02 2022-06-23 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy
EP3829595A4 (en) 2018-08-02 2022-08-24 Dyne Therapeutics, Inc. MUSCLE-DIRECTED COMPLEXES AND USES THEREOF IN THE TREATMENT OF DYSTROPHINOPATHIES
US12370264B1 (en) 2018-08-02 2025-07-29 Dyne Therapeutics, Inc. Complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and method of delivering oligonucleotide to a subject
US12018087B2 (en) 2018-08-02 2024-06-25 Dyne Therapeutics, Inc. Muscle-targeting complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and methods of delivering oligonucleotide to a subject
IL309936A (en) 2021-07-09 2024-03-01 Dyne Therapeutics Inc Muscle targeting complexes and formulations for the treatment of dystrophinopathy
US11638761B2 (en) 2021-07-09 2023-05-02 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating Facioscapulohumeral muscular dystrophy
US11771776B2 (en) 2021-07-09 2023-10-03 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating dystrophinopathies
US11672872B2 (en) 2021-07-09 2023-06-13 Dyne Therapeutics, Inc. Anti-transferrin receptor antibody and uses thereof
US11969475B2 (en) 2021-07-09 2024-04-30 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy
US11633498B2 (en) 2021-07-09 2023-04-25 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating myotonic dystrophy
US20250339553A1 (en) 2022-04-15 2025-11-06 Dyne Therapeutics, Inc. Muscle targeting complexes and formulations for treating myotonic dystrophy
US20250066776A1 (en) 2023-04-27 2025-02-27 Sarepta Therapeutics, Inc. Antisense oligomers for treatment of chronic kidney disease
US20240368596A1 (en) * 2023-05-05 2024-11-07 Biomarin Pharmaceutical Inc. Dystrophin exon skipping oligonucleotides
AU2024299328A1 (en) 2023-07-21 2026-01-22 Marrow Therapeutics, Inc. Hematopoietic cell targeting conjugates and related methods
WO2025085810A2 (en) 2023-10-18 2025-04-24 Sarepta Therapeutics, Inc. Antisense oligomers for treatment of centronuclear myopathies

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008504222A (ja) * 2003-12-15 2008-02-14 アレクシオン ファーマシューティカルズ, インコーポレイテッド 新規の抗dc−sign抗体
PL2121751T3 (pl) * 2006-12-08 2017-07-31 Lexicon Pharmaceuticals, Inc. Przeciwciała monoklonalne przeciwko ANGPTL3
PE20141114A1 (es) * 2010-12-20 2014-09-15 Genentech Inc Anticuerpos anti-mesotelina e inmunoconjugados
RU2014109038A (ru) * 2011-08-23 2015-09-27 Рош Гликарт Аг Антитела к хондроитинсульфат протеогликану меланомы
JP2017513921A (ja) * 2014-03-03 2017-06-01 アーチャルジー、スジャータ ジストロフィン異常症を治療するためのキメラジストロフィン−vsv−gタンパク質
AR099625A1 (es) * 2014-03-21 2016-08-03 Lilly Co Eli Anticuerpos de il-21
HRP20230528T1 (hr) * 2016-03-22 2023-08-04 F. Hoffmann - La Roche Ag Bispecifične molekule t stanica aktivirane proteazom
US20200282074A1 (en) * 2017-09-22 2020-09-10 Avidity Biosciences, Inc. Nucleic acid-polypeptide compositions and methods of inducing exon skipping

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