JPWO2023283613A5 - - Google Patents

Info

Publication number
JPWO2023283613A5
JPWO2023283613A5 JP2024500479A JP2024500479A JPWO2023283613A5 JP WO2023283613 A5 JPWO2023283613 A5 JP WO2023283613A5 JP 2024500479 A JP2024500479 A JP 2024500479A JP 2024500479 A JP2024500479 A JP 2024500479A JP WO2023283613 A5 JPWO2023283613 A5 JP WO2023283613A5
Authority
JP
Japan
Prior art keywords
seq
oligonucleotide
complex
optionally
sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024500479A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024525611A (ja
JP2024525611A5 (https=
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/073527 external-priority patent/WO2023283613A1/en
Publication of JP2024525611A publication Critical patent/JP2024525611A/ja
Publication of JPWO2023283613A5 publication Critical patent/JPWO2023283613A5/ja
Publication of JP2024525611A5 publication Critical patent/JP2024525611A5/ja
Pending legal-status Critical Current

Links

JP2024500479A 2021-07-09 2022-07-08 筋標的化複合体およびジストロフィノパチーを処置するためのその使用 Pending JP2024525611A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163219999P 2021-07-09 2021-07-09
US63/219,999 2021-07-09
PCT/US2022/073527 WO2023283613A1 (en) 2021-07-09 2022-07-08 Muscle targeting complexes and uses thereof for treating dystrophinopathies

Publications (3)

Publication Number Publication Date
JP2024525611A JP2024525611A (ja) 2024-07-12
JPWO2023283613A5 true JPWO2023283613A5 (https=) 2025-07-16
JP2024525611A5 JP2024525611A5 (https=) 2025-07-16

Family

ID=84802088

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024500479A Pending JP2024525611A (ja) 2021-07-09 2022-07-08 筋標的化複合体およびジストロフィノパチーを処置するためのその使用

Country Status (10)

Country Link
US (1) US20240318176A1 (https=)
EP (1) EP4367147A4 (https=)
JP (1) JP2024525611A (https=)
KR (1) KR20240032945A (https=)
CN (1) CN118355035A (https=)
AU (1) AU2022307086A1 (https=)
CA (1) CA3226365A1 (https=)
IL (1) IL309937A (https=)
MX (1) MX2024000494A (https=)
WO (1) WO2023283613A1 (https=)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20220193250A1 (en) 2018-08-02 2022-06-23 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy
US12370264B1 (en) 2018-08-02 2025-07-29 Dyne Therapeutics, Inc. Complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and method of delivering oligonucleotide to a subject
EP3829595A4 (en) 2018-08-02 2022-08-24 Dyne Therapeutics, Inc. MUSCLE-DIRECTED COMPLEXES AND USES THEREOF IN THE TREATMENT OF DYSTROPHINOPATHIES
US12097263B2 (en) 2018-08-02 2024-09-24 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating myotonic dystrophy
US12018087B2 (en) 2018-08-02 2024-06-25 Dyne Therapeutics, Inc. Muscle-targeting complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and methods of delivering oligonucleotide to a subject
US11168141B2 (en) 2018-08-02 2021-11-09 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating dystrophinopathies
US11911484B2 (en) 2018-08-02 2024-02-27 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating myotonic dystrophy
IL309936A (en) 2021-07-09 2024-03-01 Dyne Therapeutics Inc Muscle targeting complexes and formulations for the treatment of dystrophinopathy
US11771776B2 (en) 2021-07-09 2023-10-03 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating dystrophinopathies
US11638761B2 (en) 2021-07-09 2023-05-02 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating Facioscapulohumeral muscular dystrophy
US11969475B2 (en) 2021-07-09 2024-04-30 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy
US11672872B2 (en) 2021-07-09 2023-06-13 Dyne Therapeutics, Inc. Anti-transferrin receptor antibody and uses thereof
US11633498B2 (en) 2021-07-09 2023-04-25 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating myotonic dystrophy
US20250339553A1 (en) 2022-04-15 2025-11-06 Dyne Therapeutics, Inc. Muscle targeting complexes and formulations for treating myotonic dystrophy
AU2024299328A1 (en) 2023-07-21 2026-01-22 Marrow Therapeutics, Inc. Hematopoietic cell targeting conjugates and related methods
WO2025160275A1 (en) 2024-01-24 2025-07-31 Arrowhead Pharmaceuticals, Inc. Anti-transferrin receptor antibodies, conjugates thereof, and uses thereof

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008504222A (ja) * 2003-12-15 2008-02-14 アレクシオン ファーマシューティカルズ, インコーポレイテッド 新規の抗dc−sign抗体
PL2121751T3 (pl) * 2006-12-08 2017-07-31 Lexicon Pharmaceuticals, Inc. Przeciwciała monoklonalne przeciwko ANGPTL3
PE20141114A1 (es) * 2010-12-20 2014-09-15 Genentech Inc Anticuerpos anti-mesotelina e inmunoconjugados
RU2014109038A (ru) * 2011-08-23 2015-09-27 Рош Гликарт Аг Антитела к хондроитинсульфат протеогликану меланомы
CN117721110A (zh) * 2011-12-28 2024-03-19 日本新药株式会社 反义核酸
AR099625A1 (es) * 2014-03-21 2016-08-03 Lilly Co Eli Anticuerpos de il-21
HRP20230528T1 (hr) * 2016-03-22 2023-08-04 F. Hoffmann - La Roche Ag Bispecifične molekule t stanica aktivirane proteazom
US20200282074A1 (en) * 2017-09-22 2020-09-10 Avidity Biosciences, Inc. Nucleic acid-polypeptide compositions and methods of inducing exon skipping
JP7576542B2 (ja) * 2018-08-02 2024-10-31 ダイン セラピューティクス,インコーポレーテッド 筋標的化複合体およびそれらの使用
EP3829595A4 (en) * 2018-08-02 2022-08-24 Dyne Therapeutics, Inc. MUSCLE-DIRECTED COMPLEXES AND USES THEREOF IN THE TREATMENT OF DYSTROPHINOPATHIES
US12497615B2 (en) * 2019-04-25 2025-12-16 Avidity Biosciences, Inc. Nucleic acid compositions and methods of multi-exon skipping
WO2021142313A1 (en) * 2020-01-10 2021-07-15 Dyne Therapeutics, Inc. Muscle-targeting complexes and uses thereof
JP7780691B2 (ja) * 2020-01-10 2025-12-05 ダイン セラピューティクス,インコーポレーテッド ジストロフィン異常症を処置するための筋標的化複合体およびそれらの使用
KR20230044242A (ko) * 2020-07-23 2023-04-03 다인 세라퓨틱스, 인크. 근육 표적화 복합체 및 디스트로핀병증을 치료하기 위한 그의 용도

Similar Documents

Publication Publication Date Title
IL309937A (en) Muscle targeting complexes and uses thereof for treating dystrophinopathies
IL309935A (en) Muscle targeting complexes and uses thereof for treating dystrophinopathies
IL309911A (en) Muscle targeting complexes and uses thereof for treating dystrophinopathies
IL309909A (en) Muscle targeting complexes and uses thereof for treating dystrophinopathies
IL309912A (en) Muscle targeting complexes and their uses for the treatment of dystrophinopathy
JPWO2023283624A5 (https=)
JPWO2023283615A5 (https=)
JPWO2023283613A5 (https=)
JPWO2023283619A5 (https=)
JPWO2023283614A5 (https=)
JPWO2021142307A5 (https=)
JPWO2022020107A5 (https=)
US20240117356A1 (en) Muscle targeting complexes and uses thereof for treating myotonic dystrophy
US20240216522A1 (en) Muscle targeting complexes and uses thereof for treating friedreich's ataxia
IL309936A (en) Muscle targeting complexes and formulations for the treatment of dystrophinopathy
CA3226301A1 (en) Muscle targeting complexes and uses thereof for treating myotonic dystrophy
JP2024540199A (ja) ジストロフィノパチーを処置するための筋標的化複合体
IL315944A (en) Muscle targeting complexes and uses thereof for treating myotonic dystrophy
IL316206A (en) Dosage of muscle targeting complexes for the treatment of myotonic dystrophy
IL311507A (en) Dosing of muscle targeting complexes for the treatment of dystrophinopathy
JP2026503873A (ja) Dmd遺伝子のエクソン45をスキップするための筋肉標的化複合体およびその使用
IL312170A (en) Muscle targeting complexes for treating facioscapulohumeral muscular dystrophy
IL316143A (en) Muscle targeting complexes and formulations for the treatment of myotonic dystrophy
JPWO2020028832A5 (https=)
JPWO2021142313A5 (https=)