JPWO2023282704A5 - - Google Patents

Info

Publication number
JPWO2023282704A5
JPWO2023282704A5 JP2024500173A JP2024500173A JPWO2023282704A5 JP WO2023282704 A5 JPWO2023282704 A5 JP WO2023282704A5 JP 2024500173 A JP2024500173 A JP 2024500173A JP 2024500173 A JP2024500173 A JP 2024500173A JP WO2023282704 A5 JPWO2023282704 A5 JP WO2023282704A5
Authority
JP
Japan
Prior art keywords
antisense strand
sense strand
strand
rnai formulation
rnai
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024500173A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024525078A (ja
JP2024525078A5 (https=
JP7853399B2 (ja
Publication date
Application filed filed Critical
Priority claimed from PCT/KR2022/009984 external-priority patent/WO2023282704A1/ko
Publication of JP2024525078A publication Critical patent/JP2024525078A/ja
Publication of JP2024525078A5 publication Critical patent/JP2024525078A5/ja
Publication of JPWO2023282704A5 publication Critical patent/JPWO2023282704A5/ja
Application granted granted Critical
Publication of JP7853399B2 publication Critical patent/JP7853399B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2024500173A 2021-07-08 2022-07-08 ＭＡＲＣ１遺伝子を標的にするＲＮＡｉ製剤及びその用途 Active JP7853399B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR10-2021-0089864 2021-07-08
KR20210089864 2021-07-08
PCT/KR2022/009984 WO2023282704A1 (ko) 2021-07-08 2022-07-08 Marc1 유전자를 표적으로 하는 rnai 제제 및 이의 용도

Publications (4)

Publication Number Publication Date
JP2024525078A JP2024525078A (ja) 2024-07-09
JP2024525078A5 JP2024525078A5 (https=) 2026-01-20
JPWO2023282704A5 true JPWO2023282704A5 (https=) 2026-01-20
JP7853399B2 JP7853399B2 (ja) 2026-04-28

Family

ID=

Similar Documents

Publication Publication Date Title
TWI870358B (zh) 用於抑制17β-HSD第13型(HSD17B13)表現之RNAi藥劑、其組合物及使用方法
JP2025011138A (ja) アンジオテンシノーゲンの発現を調節するための化合物及び方法
AU2015240761B2 (en) Compositions for modulating SOD-1 expression
US9796976B2 (en) Methods and compositions for modulating alpha-1 antitrypsin expression
JP6833705B2 (ja) Ｔｍｐｒｓｓ６発現を調節するための化合物及び方法
AU2014312196B2 (en) Modulation of prekallikrein (PKK) expression
JP6752151B2 (ja) 遺伝子サイレンシングにおいて低下したｏｆｆ−ｔａｒｇｅｔ効果を有するｕｎａオリゴマー
PT2015758E (pt) Compostos e métodos para modular a expressão da proteína apob
EA035433B1 (ru) Модуляторы фактора в комплемента
EA029137B1 (ru) Модулирование экспрессии вируса гепатита в (hbv)
CN115397436A (zh) 用于抑制PNPLA3表达的RNAi剂、其药物组合物和使用方法
JP2016523548A (ja) 成長ホルモン受容体のモジュレータ
JP5951752B2 (ja) Ｐｔｐ１ｂ発現のアンチセンス調節
JP2023506546A (ja) Ｂ型肝炎ウイルス感染症を処置するためのｓｅｐｔ９阻害剤の使用
JP5406024B2 (ja) Ｂｃｌ−ＸＬ特異的ｓｉＮＡを用いる癌治療法
JPWO2023282704A5 (https=)
CN116370491A (zh) 反义寡核苷酸剂在治疗冠状病毒相关疾病中的应用
WO2013130868A1 (en) Methods for modulating fibrinogen expression
WO2022270071A1 (ja) 肝線維化抑制のための剤及び医薬組成物
CN101076341A (zh) 酪蛋白激酶2反义疗法
JP2018512140A (ja) 治療上のｕｎａオリゴマーおよびその使用
WO2025199231A2 (en) Mucin-5b (muc5b) targeted sirna and antisense oligonucleotides and methods of use thereof
WO2024098061A2 (en) Oligonucleotide-based therapeutics targeting cyclin d2 for the treatment of heart failure
CN120210192A (zh) Hsd17b13表达抑制物及其用途
HK40120876A (en) Compounds and methods for modulating angiotensinogen expression