JPWO2023217437A5 - - Google Patents
Info
- Publication number
- JPWO2023217437A5 JPWO2023217437A5 JP2024564846A JP2024564846A JPWO2023217437A5 JP WO2023217437 A5 JPWO2023217437 A5 JP WO2023217437A5 JP 2024564846 A JP2024564846 A JP 2024564846A JP 2024564846 A JP2024564846 A JP 2024564846A JP WO2023217437 A5 JPWO2023217437 A5 JP WO2023217437A5
- Authority
- JP
- Japan
- Prior art keywords
- hnrnp
- mapt
- medicament
- inhibit
- mrna
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202263364629P | 2022-05-13 | 2022-05-13 | |
| US63/364,629 | 2022-05-13 | ||
| US202263382536P | 2022-11-07 | 2022-11-07 | |
| US63/382,536 | 2022-11-07 | ||
| PCT/EP2023/056392 WO2023217437A1 (en) | 2022-05-13 | 2023-03-13 | Method and molecules for reducing axonal tau protein accumulation through blocking of hnrnp r-mediated mapt mrna transport for treatment of alzheimer's disease |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2025517123A JP2025517123A (ja) | 2025-06-03 |
| JPWO2023217437A5 true JPWO2023217437A5 (https=) | 2025-12-09 |
| JP2025517123A5 JP2025517123A5 (https=) | 2025-12-09 |
Family
ID=85685250
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024564846A Pending JP2025517123A (ja) | 2022-05-13 | 2023-03-13 | アルツハイマー病の処置のためのHNRNP R-媒介Mapt mRNA輸送の遮断を介する軸索タウ(tau)タンパク質蓄積を減少させるための方法及び分子 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20250304958A1 (https=) |
| EP (1) | EP4522217A1 (https=) |
| JP (1) | JP2025517123A (https=) |
| AU (1) | AU2023267136A1 (https=) |
| CA (1) | CA3246379A1 (https=) |
| WO (1) | WO2023217437A1 (https=) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI772856B (zh) * | 2013-07-19 | 2022-08-01 | 美商百健Ma公司 | 用於調節τ蛋白表現之組合物 |
| AU2016215155A1 (en) * | 2015-02-04 | 2017-08-17 | F. Hoffmann-La Roche Ag | Tau antisense oligomers and uses thereof |
| AU2021238319A1 (en) * | 2020-03-18 | 2022-10-06 | University Of Massachusetts | Oligonucleotides for MAPT modulation |
-
2023
- 2023-03-13 WO PCT/EP2023/056392 patent/WO2023217437A1/en not_active Ceased
- 2023-03-13 EP EP23711444.2A patent/EP4522217A1/en active Pending
- 2023-03-13 JP JP2024564846A patent/JP2025517123A/ja active Pending
- 2023-03-13 CA CA3246379A patent/CA3246379A1/en active Pending
- 2023-03-13 US US18/865,204 patent/US20250304958A1/en active Pending
- 2023-03-13 AU AU2023267136A patent/AU2023267136A1/en active Pending
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