JPWO2023209327A5 - - Google Patents

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Publication number
JPWO2023209327A5
JPWO2023209327A5 JP2024563505A JP2024563505A JPWO2023209327A5 JP WO2023209327 A5 JPWO2023209327 A5 JP WO2023209327A5 JP 2024563505 A JP2024563505 A JP 2024563505A JP 2024563505 A JP2024563505 A JP 2024563505A JP WO2023209327 A5 JPWO2023209327 A5 JP WO2023209327A5
Authority
JP
Japan
Prior art keywords
bont
muscle
unit dose
dose
unit
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024563505A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025515346A (ja
JP2025515346A5 (https=
Publication date
Priority claimed from GBGB2206361.4A external-priority patent/GB202206361D0/en
Application filed filed Critical
Publication of JP2025515346A publication Critical patent/JP2025515346A/ja
Publication of JP2025515346A5 publication Critical patent/JP2025515346A5/ja
Publication of JPWO2023209327A5 publication Critical patent/JPWO2023209327A5/ja
Pending legal-status Critical Current

Links

JP2024563505A 2022-04-29 2023-03-23 顔面ジストニアを治療する用途のＢｏＮＴ／Ａ Pending JP2025515346A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB2206361.4A GB202206361D0 (en) 2022-04-29 2022-04-29 Treatment of a facial dystonia
GB2206361.4 2022-04-29
PCT/GB2023/050746 WO2023209327A1 (en) 2022-04-29 2023-03-23 Bont/a for use in treating a facial dystonia

Publications (3)

Publication Number Publication Date
JP2025515346A JP2025515346A (ja) 2025-05-14
JP2025515346A5 JP2025515346A5 (https=) 2026-03-30
JPWO2023209327A5 true JPWO2023209327A5 (https=) 2026-03-30

Family

ID=81943823

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024563505A Pending JP2025515346A (ja) 2022-04-29 2023-03-23 顔面ジストニアを治療する用途のＢｏＮＴ／Ａ

Country Status (9)

Country Link
US (1) US20250213662A1 (https=)
EP (1) EP4514824A1 (https=)
JP (1) JP2025515346A (https=)
KR (1) KR20250004870A (https=)
CN (1) CN119095868A (https=)
AU (1) AU2023262229A1 (https=)
CA (1) CA3245925A1 (https=)
GB (1) GB202206361D0 (https=)
WO (1) WO2023209327A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025093844A1 (en) * 2023-11-01 2025-05-08 Ipsen Biopharm Limited Use of chimeric botulinum toxin a for treating blepharospasm and hemifacial spasm

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
IL99552A0 (en) 1990-09-28 1992-08-18 Ixsys Inc Compositions containing procaryotic cells,a kit for the preparation of vectors useful for the coexpression of two or more dna sequences and methods for the use thereof
DE102004043009A1 (de) 2004-09-06 2006-03-23 Toxogen Gmbh Transportprotein zum Einbringen chemischer Verbindungen in Nervenzellen
DE102005019302A1 (de) 2005-04-26 2006-11-16 Toxogen Gmbh Carrier zum Targeting von Nervenzellen
ES2369558T3 (es) 2005-09-19 2011-12-01 Allergan, Inc. Toxinas clostridiales y toxinas clostridiales activables.
CA2758274C (en) 2009-04-14 2018-04-10 Mcw Research Foundation, Inc. Engineered botulinum neurotoxin
US8853360B2 (en) 2010-06-23 2014-10-07 Wisconsin Alumni Research Foundation Engineered botulinum neurotoxin C1 with selective substrate specificity
EP3162894B1 (en) 2011-05-19 2024-01-10 Ipsen Bioinnovation Limited Methods for the manufacture of proteolytically processed polypeptides
SG10201606666XA (en) 2012-05-30 2016-09-29 Harvard College Engineered Botulinum Neurotoxin
WO2014079495A1 (en) 2012-11-21 2014-05-30 Syntaxin Limited Methods for the manufacture of proteolytically processed polypeptides
PT3274364T (pt) 2015-03-26 2021-11-05 Harvard College Neurotoxina botulínica manipulada
GB201607901D0 (en) 2016-05-05 2016-06-22 Ipsen Biopharm Ltd Chimeric neurotoxins
EP3481852B1 (en) 2016-07-08 2022-12-07 Children's Medical Center Corporation A novel botulinum neurotoxin and its derivatives
GB202003813D0 (en) * 2020-03-16 2020-04-29 Ipsen Biopharm Ltd Treatment of upper facial lines
KR20240067100A (ko) * 2021-09-23 2024-05-16 입센 바이오팜 리미티드 대상체의 안검 근육에 이환된 장애의 치료에 사용하기 위한 변형된 bont/a

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