JPWO2023169226A5 - - Google Patents
Info
- Publication number
- JPWO2023169226A5 JPWO2023169226A5 JP2024553758A JP2024553758A JPWO2023169226A5 JP WO2023169226 A5 JPWO2023169226 A5 JP WO2023169226A5 JP 2024553758 A JP2024553758 A JP 2024553758A JP 2024553758 A JP2024553758 A JP 2024553758A JP WO2023169226 A5 JPWO2023169226 A5 JP WO2023169226A5
- Authority
- JP
- Japan
- Prior art keywords
- methyl
- optionally substituted
- piperazin
- methylcarbamoyl
- pyridin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210260944 | 2022-03-11 | ||
| CN202210260944.7 | 2022-03-11 | ||
| CN202210448803 | 2022-04-24 | ||
| CN202210448803.8 | 2022-04-24 | ||
| CN202211219599 | 2022-09-30 | ||
| CN202211219599.9 | 2022-09-30 | ||
| CN202211505904.0 | 2022-11-28 | ||
| CN202211505904 | 2022-11-28 | ||
| PCT/CN2023/077988 WO2023169226A1 (en) | 2022-03-11 | 2023-02-23 | Substituted tricyclic compounds as parp inhibitors and the use thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2025508122A JP2025508122A (ja) | 2025-03-21 |
| JPWO2023169226A5 true JPWO2023169226A5 (https=) | 2026-03-04 |
| JP2025508122A5 JP2025508122A5 (https=) | 2026-03-04 |
Family
ID=87937164
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024553758A Pending JP2025508122A (ja) | 2022-03-11 | 2023-02-23 | Ｐａｒｐ阻害剤としての置換三環式化合物およびその使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20250215013A1 (https=) |
| EP (1) | EP4490161A4 (https=) |
| JP (1) | JP2025508122A (https=) |
| KR (1) | KR20240162104A (https=) |
| CN (1) | CN119013279A (https=) |
| AU (1) | AU2023229992A1 (https=) |
| CA (1) | CA3253468A1 (https=) |
| IL (1) | IL315586A (https=) |
| MX (1) | MX2024011086A (https=) |
| TW (1) | TW202400601A (https=) |
| WO (1) | WO2023169226A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2023209820B2 (en) | 2022-01-21 | 2024-10-10 | Xinthera, Inc. | Parp1 inhibitors and uses thereof |
| KR20240161147A (ko) | 2022-03-14 | 2024-11-12 | 슬랩 파마슈티컬스 엘엘씨 | 다중 사이클릭 화합물 |
| FI4497438T3 (fi) | 2022-04-28 | 2025-10-20 | Xinthera Inc | Trisyklisiä parp1:n estäjiä ja niiden käyttötapoja |
| CN119110801A (zh) * | 2022-05-07 | 2024-12-10 | 南京明德新药研发有限公司 | 选择性抑制parp1的氟代喹喔啉酮衍生物 |
| JP2025538192A (ja) * | 2022-11-10 | 2025-11-26 | 上海海和薬物研究開発股▲ふん▼有限公司 | 縮合三環式ｐａｒｐ１阻害剤、その調製方法、および使用 |
| EP4673448A1 (en) * | 2023-03-01 | 2026-01-07 | Impact Therapeutics (Shanghai), Inc. | Substituted nitrogen-containing tricyclic compounds as parp inhibitors and the use thereof |
| CN120677162A (zh) * | 2023-06-13 | 2025-09-19 | 中国医药研究开发中心有限公司 | 含氮杂环类化合物及其医药用途 |
| TW202525808A (zh) * | 2023-09-13 | 2025-07-01 | 大陸商上海瑛派藥業有限公司 | 用作ｐａｒｐ１抑制劑的化合物、其用途及包含其之組合物 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPS137402A0 (en) * | 2002-03-26 | 2002-05-09 | Fujisawa Pharmaceutical Co., Ltd. | Novel tricyclic compounds |
| CN101528704B (zh) * | 2006-09-01 | 2014-04-09 | 生华生物科技股份有限公司 | 丝氨酸-苏氨酸蛋白激酶和parp调节剂 |
| CN101616919B (zh) * | 2006-12-28 | 2012-10-10 | 雅培制药有限公司 | 聚（adp核糖）聚合酶抑制剂 |
| KR101779137B1 (ko) * | 2009-01-23 | 2017-09-18 | 다케다 야쿠힌 고교 가부시키가이샤 | 폴리(ａｄｐ-리보스)폴리머라제(ｐａｒｐ) 억제제 |
| EP2459561A1 (en) * | 2009-07-30 | 2012-06-06 | Takeda Pharmaceutical Company Limited | Poly (adp-ribose) polymerase (parp) inhibitors |
| PH12017502228B1 (en) * | 2015-06-09 | 2022-08-03 | Onconic Therapeutics Inc | Tricyclic derivative compound, method for preparing same, and pharmaceutical composition comprising same |
| TW202309025A (zh) * | 2021-04-19 | 2023-03-01 | 美商辛瑟拉股份有限公司 | Parp1抑制劑及其用途 |
| AU2022334408A1 (en) * | 2021-08-27 | 2024-02-15 | Impact Therapeutics (Shanghai), Inc. | Substituted tricyclic compounds as parp inhibitors and use thereof |
| JP2025501762A (ja) * | 2021-12-22 | 2025-01-23 | シノベーション・セラピューティクス・インコーポレイテッド | Ｐａｒｐ１阻害剤 |
| WO2023134647A1 (zh) * | 2022-01-13 | 2023-07-20 | 优领医药科技(香港)有限公司 | 含哌嗪并环类衍生物、其药学上可接受的盐及其制备方法和应用 |
| FI4497438T3 (fi) * | 2022-04-28 | 2025-10-20 | Xinthera Inc | Trisyklisiä parp1:n estäjiä ja niiden käyttötapoja |
| CN119110801A (zh) * | 2022-05-07 | 2024-12-10 | 南京明德新药研发有限公司 | 选择性抑制parp1的氟代喹喔啉酮衍生物 |
| CN115232129B (zh) * | 2022-08-18 | 2023-12-01 | 上海闻耐医药科技有限公司 | 一种parp1选择性抑制剂及其制备方法和用途 |
| JP2025538192A (ja) * | 2022-11-10 | 2025-11-26 | 上海海和薬物研究開発股▲ふん▼有限公司 | 縮合三環式ｐａｒｐ１阻害剤、その調製方法、および使用 |
-
2023
- 2023-02-23 IL IL315586A patent/IL315586A/en unknown
- 2023-02-23 WO PCT/CN2023/077988 patent/WO2023169226A1/en not_active Ceased
- 2023-02-23 KR KR1020247033867A patent/KR20240162104A/ko active Pending
- 2023-02-23 US US18/846,265 patent/US20250215013A1/en active Pending
- 2023-02-23 EP EP23765804.2A patent/EP4490161A4/en active Pending
- 2023-02-23 CN CN202380026468.5A patent/CN119013279A/zh active Pending
- 2023-02-23 CA CA3253468A patent/CA3253468A1/en active Pending
- 2023-02-23 JP JP2024553758A patent/JP2025508122A/ja active Pending
- 2023-02-23 AU AU2023229992A patent/AU2023229992A1/en active Pending
- 2023-03-01 TW TW112107292A patent/TW202400601A/zh unknown
-
2024
- 2024-09-10 MX MX2024011086A patent/MX2024011086A/es unknown
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