JPWO2023127871A5 - - Google Patents
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- JPWO2023127871A5 JPWO2023127871A5 JP2023571048A JP2023571048A JPWO2023127871A5 JP WO2023127871 A5 JPWO2023127871 A5 JP WO2023127871A5 JP 2023571048 A JP2023571048 A JP 2023571048A JP 2023571048 A JP2023571048 A JP 2023571048A JP WO2023127871 A5 JPWO2023127871 A5 JP WO2023127871A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- protein
- strand rna
- acid mutations
- mutations corresponding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 230000035772 mutation Effects 0.000 claims 47
- 150000001413 amino acids Chemical class 0.000 claims 38
- 241001493065 dsRNA viruses Species 0.000 claims 26
- 239000013603 viral vector Substances 0.000 claims 22
- 210000004027 cell Anatomy 0.000 claims 21
- 108090000623 proteins and genes Proteins 0.000 claims 18
- 108091032973 (ribonucleotides)n+m Proteins 0.000 claims 14
- 102000040650 (ribonucleotides)n+m Human genes 0.000 claims 14
- 102000039446 nucleic acids Human genes 0.000 claims 12
- 108020004707 nucleic acids Proteins 0.000 claims 12
- 150000007523 nucleic acids Chemical class 0.000 claims 12
- 102100034574 P protein Human genes 0.000 claims 9
- 101710181008 P protein Proteins 0.000 claims 9
- 101710177166 Phosphoprotein Proteins 0.000 claims 9
- 238000000034 method Methods 0.000 claims 9
- 238000006467 substitution reaction Methods 0.000 claims 9
- 125000003275 alpha amino acid group Chemical group 0.000 claims 8
- 102000004169 proteins and genes Human genes 0.000 claims 8
- 238000012258 culturing Methods 0.000 claims 7
- 239000013598 vector Substances 0.000 claims 7
- 101001065501 Escherichia phage MS2 Lysis protein Proteins 0.000 claims 5
- 230000003612 virological effect Effects 0.000 claims 5
- 101710133291 Hemagglutinin-neuraminidase Proteins 0.000 claims 4
- 101710085938 Matrix protein Proteins 0.000 claims 4
- 101710127721 Membrane protein Proteins 0.000 claims 4
- 230000015556 catabolic process Effects 0.000 claims 4
- 238000006731 degradation reaction Methods 0.000 claims 4
- 230000001939 inductive effect Effects 0.000 claims 4
- 210000004102 animal cell Anatomy 0.000 claims 3
- 238000004519 manufacturing process Methods 0.000 claims 3
- 241000711408 Murine respirovirus Species 0.000 claims 2
- 241000700605 Viruses Species 0.000 claims 1
- 108020001507 fusion proteins Proteins 0.000 claims 1
- 102000037865 fusion proteins Human genes 0.000 claims 1
- 230000035945 sensitivity Effects 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025024072A JP2025081483A (ja) | 2021-12-27 | 2025-02-18 | 温度感受性のマイナス鎖ｒｎａウイルスまたはウイルスベクターおよびそのｒｎａゲノム |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021213114 | 2021-12-27 | ||
| PCT/JP2022/048141 WO2023127871A1 (ja) | 2021-12-27 | 2022-12-27 | 温度感受性のマイナス鎖ｒｎａウイルスまたはウイルスベクターおよびそのｒｎａゲノム |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025024072A Division JP2025081483A (ja) | 2021-12-27 | 2025-02-18 | 温度感受性のマイナス鎖ｒｎａウイルスまたはウイルスベクターおよびそのｒｎａゲノム |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPWO2023127871A1 JPWO2023127871A1 (https=) | 2023-07-06 |
| JPWO2023127871A5 true JPWO2023127871A5 (https=) | 2024-10-03 |
Family
ID=86998996
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023571048A Pending JPWO2023127871A1 (https=) | 2021-12-27 | 2022-12-27 | |
| JP2025024072A Pending JP2025081483A (ja) | 2021-12-27 | 2025-02-18 | 温度感受性のマイナス鎖ｒｎａウイルスまたはウイルスベクターおよびそのｒｎａゲノム |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025024072A Pending JP2025081483A (ja) | 2021-12-27 | 2025-02-18 | 温度感受性のマイナス鎖ｒｎａウイルスまたはウイルスベクターおよびそのｒｎａゲノム |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20250333760A1 (https=) |
| EP (1) | EP4458974A1 (https=) |
| JP (2) | JPWO2023127871A1 (https=) |
| CN (1) | CN118475700A (https=) |
| AU (1) | AU2022424476A1 (https=) |
| CA (1) | CA3243062A1 (https=) |
| WO (1) | WO2023127871A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPWO2024195811A1 (https=) * | 2023-03-22 | 2024-09-26 | ||
| WO2025033445A1 (ja) | 2023-08-07 | 2025-02-13 | 株式会社Logomix | 遺伝子をコンディショナルに不活化させる方法、およびそのための細胞 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4206154B2 (ja) | 1997-11-13 | 2009-01-07 | 大日本住友製薬株式会社 | 変異型ｌｏｘＰ配列とその応用 |
| JP4787440B2 (ja) | 1999-09-30 | 2011-10-05 | 泉 斎藤 | 変異型ｆｒｔ配列を含有してなるｄｎａ |
| JPWO2003025570A1 (ja) * | 2001-09-18 | 2004-12-24 | 株式会社ディナベック研究所 | 粒子形成能が低下した（−）鎖ｒｎａウィルスベクターの検査方法および製造方法 |
| JP4999330B2 (ja) | 2004-01-22 | 2012-08-15 | 株式会社ディナベック研究所 | サイトメガロウイルスエンハンサーおよびニワトリβ−アクチンプロモーターを含むハイブリッドプロモーターを利用したマイナス鎖ＲＮＡウイルスベクターの製造方法 |
| JPWO2005071085A1 (ja) | 2004-01-22 | 2007-09-06 | 株式会社ディナベック研究所 | ウイルスベクターの製造方法 |
| JP2006180780A (ja) * | 2004-12-27 | 2006-07-13 | National Institute Of Advanced Industrial & Technology | 持続感染型センダイウイルスベクター |
| US8173792B2 (en) | 2007-02-09 | 2012-05-08 | The Board Of Trustees Of The Leland Stanford Junior University | Method for regulating protein function in cells using synthetic small molecules |
| US8530636B2 (en) * | 2008-05-07 | 2013-09-10 | The Board Of Trustees Of The Leland Stanford Junior University | Method for regulating protein function in cells in vivo using synthetic small molecules |
| US9127256B2 (en) * | 2008-07-16 | 2015-09-08 | Dnavec Corporation | Method for production of reprogrammed cell using chromosomally unintegrated virus vector |
| CA2809515A1 (en) | 2010-08-30 | 2012-03-08 | Dnavec Corporation | Composition for inducing pluripotent stem cell, and use thereof |
| WO2017082174A1 (ja) * | 2015-11-13 | 2017-05-18 | 株式会社Ｉｄファーマ | 改良されたパラミクソウイルスベクター |
-
2022
- 2022-12-27 WO PCT/JP2022/048141 patent/WO2023127871A1/ja not_active Ceased
- 2022-12-27 JP JP2023571048A patent/JPWO2023127871A1/ja active Pending
- 2022-12-27 CN CN202280085608.1A patent/CN118475700A/zh active Pending
- 2022-12-27 US US18/724,497 patent/US20250333760A1/en active Pending
- 2022-12-27 AU AU2022424476A patent/AU2022424476A1/en active Pending
- 2022-12-27 EP EP22916094.0A patent/EP4458974A1/en active Pending
- 2022-12-27 CA CA3243062A patent/CA3243062A1/en active Pending
-
2025
- 2025-02-18 JP JP2025024072A patent/JP2025081483A/ja active Pending
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