JPWO2023120673A1 - - Google Patents

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Publication number
JPWO2023120673A1
JPWO2023120673A1 JP2023569552A JP2023569552A JPWO2023120673A1 JP WO2023120673 A1 JPWO2023120673 A1 JP WO2023120673A1 JP 2023569552 A JP2023569552 A JP 2023569552A JP 2023569552 A JP2023569552 A JP 2023569552A JP WO2023120673 A1 JPWO2023120673 A1 JP WO2023120673A1
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JP
Japan
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JP2023569552A
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Japanese (ja)
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JPWO2023120673A5 (https=
JP7452918B2 (ja
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0645—Macrophages, e.g. Kuepfer cells in the liver; Monocytes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/36—Lipids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/70—Undefined extracts
    • C12N2500/80—Undefined extracts from animals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/22—Colony stimulating factors (G-CSF, GM-CSF)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
    • C12N2501/2306—Interleukin-6 (IL-6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/25—Tumour necrosing factors [TNF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/998—Proteins not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/11—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from blood or immune system cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP2023569552A 2021-12-22 2022-12-22 マクロファージの製造方法、分化誘導剤、分化誘導キット、マクロファージの分化誘導方法、マクロファージの増殖促進剤、マクロファージの増殖促進キット、マクロファージの増殖方法及びマクロファージ Active JP7452918B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024020753A JP2024040454A (ja) 2021-12-22 2024-02-15 マクロファージの製造方法、分化誘導剤、分化誘導キット、マクロファージの培養方法、マクロファージの増殖促進剤、マクロファージの増殖促進キット、マクロファージの増殖方法及びマクロファージ

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2021208420 2021-12-22
JP2021208420 2021-12-22
PCT/JP2022/047472 WO2023120673A1 (ja) 2021-12-22 2022-12-22 マクロファージの製造方法、分化誘導剤、分化誘導キット、マクロファージの培養方法、マクロファージの増殖促進剤、マクロファージの増殖促進キット、マクロファージの増殖方法及びマクロファージ

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024020753A Division JP2024040454A (ja) 2021-12-22 2024-02-15 マクロファージの製造方法、分化誘導剤、分化誘導キット、マクロファージの培養方法、マクロファージの増殖促進剤、マクロファージの増殖促進キット、マクロファージの増殖方法及びマクロファージ

Publications (3)

Publication Number Publication Date
JPWO2023120673A1 true JPWO2023120673A1 (https=) 2023-06-29
JPWO2023120673A5 JPWO2023120673A5 (https=) 2024-01-19
JP7452918B2 JP7452918B2 (ja) 2024-03-19

Family

ID=86902764

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2023569552A Active JP7452918B2 (ja) 2021-12-22 2022-12-22 マクロファージの製造方法、分化誘導剤、分化誘導キット、マクロファージの分化誘導方法、マクロファージの増殖促進剤、マクロファージの増殖促進キット、マクロファージの増殖方法及びマクロファージ
JP2024020753A Pending JP2024040454A (ja) 2021-12-22 2024-02-15 マクロファージの製造方法、分化誘導剤、分化誘導キット、マクロファージの培養方法、マクロファージの増殖促進剤、マクロファージの増殖促進キット、マクロファージの増殖方法及びマクロファージ

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2024020753A Pending JP2024040454A (ja) 2021-12-22 2024-02-15 マクロファージの製造方法、分化誘導剤、分化誘導キット、マクロファージの培養方法、マクロファージの増殖促進剤、マクロファージの増殖促進キット、マクロファージの増殖方法及びマクロファージ

Country Status (4)

Country Link
US (1) US20250059509A1 (https=)
EP (1) EP4455275A4 (https=)
JP (2) JP7452918B2 (https=)
WO (1) WO2023120673A1 (https=)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017136014A (ja) * 2016-02-03 2017-08-10 富士ソフト株式会社 Ｍ２様マクロファージ組成物の製造方法、およびｍ２様マクロファージ組成物原料
JP2017523814A (ja) * 2014-08-08 2017-08-24 アレクトル エルエルシー 抗ｔｒｅｍ２抗体及びその使用方法
JP2018522556A (ja) * 2015-07-23 2018-08-16 コリア リサーチ インスティチュート オブ ケミカル テクノロジーＫｏｒｅａ Ｒｅｓｅａｒｃｈ Ｉｎｓｔｉｔｕｔｅ Ｏｆ Ｃｈｅｍｉｃａｌ Ｔｅｃｈｎｏｌｏｇｙ 脂肪細胞とマクロファージの三次元共培養方法
JP2021513329A (ja) * 2018-01-31 2021-05-27 アレクター リミテッド ライアビリティ カンパニー 抗ｍｓ４ａ４ａ抗体及びその使用方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015047125A (ja) 2013-09-02 2015-03-16 テルモ株式会社 マクロファージの分化誘導剤およびそれを用いるマクロファージの分化誘導方法
AU2016334051B2 (en) * 2015-10-06 2023-10-26 Alector Llc Anti-TREM2 antibodies and methods of use thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017523814A (ja) * 2014-08-08 2017-08-24 アレクトル エルエルシー 抗ｔｒｅｍ２抗体及びその使用方法
JP2018522556A (ja) * 2015-07-23 2018-08-16 コリア リサーチ インスティチュート オブ ケミカル テクノロジーＫｏｒｅａ Ｒｅｓｅａｒｃｈ Ｉｎｓｔｉｔｕｔｅ Ｏｆ Ｃｈｅｍｉｃａｌ Ｔｅｃｈｎｏｌｏｇｙ 脂肪細胞とマクロファージの三次元共培養方法
JP2017136014A (ja) * 2016-02-03 2017-08-10 富士ソフト株式会社 Ｍ２様マクロファージ組成物の製造方法、およびｍ２様マクロファージ組成物原料
JP2021513329A (ja) * 2018-01-31 2021-05-27 アレクター リミテッド ライアビリティ カンパニー 抗ｍｓ４ａ４ａ抗体及びその使用方法

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
BMC IMMUNOLOGY, JPN6023029198, May 2021 (2021-05-01), pages 22 - 30, ISSN: 0005239431 *
CELL, vol. 169, JPN6023029195, 2017, pages 1276 - 1290, ISSN: 0005239433 *
CELL, vol. 178, JPN6023029196, 2019, pages 686 - 698, ISSN: 0005239432 *
DIABETES, vol. 64, JPN6023029197, 2015, pages 117 - 127, ISSN: 0005239430 *
NATURE COMMUNICATIONS, vol. 12, no. 1, JPN6023029193, April 2021 (2021-04-01), pages 2299, ISSN: 0005239428 *
THE JOURNAL OF IMMUNOLOGY, vol. 184, JPN6023029194, 2010, pages 6522 - 6528, ISSN: 0005239429 *

Also Published As

Publication number Publication date
US20250059509A1 (en) 2025-02-20
EP4455275A4 (en) 2026-03-18
JP2024040454A (ja) 2024-03-25
EP4455275A1 (en) 2024-10-30
JP7452918B2 (ja) 2024-03-19
WO2023120673A1 (ja) 2023-06-29

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