JPWO2023102407A5 - - Google Patents

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Publication number
JPWO2023102407A5
JPWO2023102407A5 JP2024532887A JP2024532887A JPWO2023102407A5 JP WO2023102407 A5 JPWO2023102407 A5 JP WO2023102407A5 JP 2024532887 A JP2024532887 A JP 2024532887A JP 2024532887 A JP2024532887 A JP 2024532887A JP WO2023102407 A5 JPWO2023102407 A5 JP WO2023102407A5
Authority
JP
Japan
Prior art keywords
amino acid
omni
acid substitution
nuclease variant
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024532887A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024542883A (ja
JP2024542883A5 (https=
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/080627 external-priority patent/WO2023102407A2/en
Publication of JP2024542883A publication Critical patent/JP2024542883A/ja
Publication of JPWO2023102407A5 publication Critical patent/JPWO2023102407A5/ja
Publication of JP2024542883A5 publication Critical patent/JP2024542883A5/ja
Pending legal-status Critical Current

Links

JP2024532887A 2021-12-01 2022-11-30 改変された忠実度の高いomni-79ヌクレアーゼバリアント Pending JP2024542883A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163284858P 2021-12-01 2021-12-01
US63/284,858 2021-12-01
PCT/US2022/080627 WO2023102407A2 (en) 2021-12-01 2022-11-30 Engineered high activity omni-79 nuclease variants

Publications (3)

Publication Number Publication Date
JP2024542883A JP2024542883A (ja) 2024-11-18
JPWO2023102407A5 true JPWO2023102407A5 (https=) 2025-12-09
JP2024542883A5 JP2024542883A5 (https=) 2025-12-09

Family

ID=86613099

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024532887A Pending JP2024542883A (ja) 2021-12-01 2022-11-30 改変された忠実度の高いomni-79ヌクレアーゼバリアント

Country Status (9)

Country Link
US (1) US20250043260A1 (https=)
EP (1) EP4441210A4 (https=)
JP (1) JP2024542883A (https=)
KR (1) KR20240135608A (https=)
CN (1) CN118647715A (https=)
AU (1) AU2022401869A1 (https=)
CA (1) CA3239753A1 (https=)
IL (1) IL313245A (https=)
WO (1) WO2023102407A2 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12091688B2 (en) 2021-02-08 2024-09-17 Emendobio Inc. OMNI-103 CRISPR nuclease
KR20230142740A (ko) 2021-02-08 2023-10-11 에멘도바이오 인코포레이티드 Omni-103 crispr 뉴클레아제

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4400597A3 (en) * 2015-10-09 2024-10-16 Monsanto Technology LLC Novel rna-guided nucleases and uses thereof
AU2018240515B2 (en) * 2017-03-24 2024-07-25 CureVac SE Nucleic acids encoding CRISPR-associated proteins and uses thereof
WO2020223514A2 (en) * 2019-04-30 2020-11-05 Emendobio Inc. Novel omni-50 crispr nuclease
WO2022119881A1 (en) * 2020-12-01 2022-06-09 Emendobio Inc. Differential knockout of a heterozygous allele of lrrk2

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