JPWO2023091644A5 - - Google Patents

Info

Publication number
JPWO2023091644A5
JPWO2023091644A5 JP2024529302A JP2024529302A JPWO2023091644A5 JP WO2023091644 A5 JPWO2023091644 A5 JP WO2023091644A5 JP 2024529302 A JP2024529302 A JP 2024529302A JP 2024529302 A JP2024529302 A JP 2024529302A JP WO2023091644 A5 JPWO2023091644 A5 JP WO2023091644A5
Authority
JP
Japan
Prior art keywords
nucleotide
double
terminal
stranded oligonucleotide
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024529302A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024545602A5 (https=
JP2024545602A (ja
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/050371 external-priority patent/WO2023091644A2/en
Publication of JP2024545602A publication Critical patent/JP2024545602A/ja
Publication of JP2024545602A5 publication Critical patent/JP2024545602A5/ja
Publication of JPWO2023091644A5 publication Critical patent/JPWO2023091644A5/ja
Pending legal-status Critical Current

Links

JP2024529302A 2021-11-19 2022-11-18 Hsd17b13関連二本鎖オリゴヌクレオチド組成物及びそれに関連する方法 Pending JP2024545602A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202163264360P 2021-11-19 2021-11-19
US63/264,360 2021-11-19
US202263268775P 2022-03-02 2022-03-02
US63/268,775 2022-03-02
US202263377482P 2022-09-28 2022-09-28
US63/377,482 2022-09-28
PCT/US2022/050371 WO2023091644A2 (en) 2021-11-19 2022-11-18 Hsd17b13-related double stranded oligonucleotide compositions and methods relating thereto

Publications (3)

Publication Number Publication Date
JP2024545602A JP2024545602A (ja) 2024-12-10
JP2024545602A5 JP2024545602A5 (https=) 2025-11-27
JPWO2023091644A5 true JPWO2023091644A5 (https=) 2025-11-27

Family

ID=86397758

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024529302A Pending JP2024545602A (ja) 2021-11-19 2022-11-18 Hsd17b13関連二本鎖オリゴヌクレオチド組成物及びそれに関連する方法

Country Status (4)

Country Link
US (1) US20240384273A1 (https=)
EP (1) EP4433596A4 (https=)
JP (1) JP2024545602A (https=)
WO (1) WO2023091644A2 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3899024A4 (en) 2018-12-21 2023-05-31 Ionis Pharmaceuticals, Inc. Modulators of hsd17b13 expression
US20240352464A1 (en) * 2023-03-07 2024-10-24 Aligos Therapeutics, Inc. Modified Short Interfering Nucleic Acid (siNA) Molecules and Uses Thereof
CN118773194A (zh) * 2023-06-16 2024-10-15 施能康医药科技(苏州)有限公司 靶向17-β-羟基类固醇脱氢酶13的核酸及其用途
WO2025184661A1 (en) * 2024-03-01 2025-09-04 Wave Life Sciences Ltd. Double stranded oligonucleotide compositions and methods relating thereto

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2917473T3 (es) * 2014-01-16 2022-07-08 Wave Life Sciences Ltd Diseño quiral
IL314915B1 (en) * 2017-01-23 2026-02-01 Regeneron Pharma Variants of 17-beta-hydroxysteroid dehydrogenase and their uses
US11603532B2 (en) * 2017-06-02 2023-03-14 Wave Life Sciences Ltd. Oligonucleotide compositions and methods of use thereof
CA3086485A1 (en) * 2017-12-21 2019-06-27 Alnylam Pharmaceuticals, Inc. Chirally-enriched double-stranded rna agents
JP7507093B2 (ja) * 2018-03-21 2024-06-27 リジェネロン・ファーマシューティカルズ・インコーポレイテッド 17β-水酸化ステロイド脱水素酵素13型(HSD17B13)iRNA組成物およびその使用方法
MX2021003077A (es) * 2018-09-19 2021-05-27 Arrowhead Pharmaceuticals Inc Agentes de arni para inhibir la expresion de 17beta-hsd tipo 13 (hsd17b13), composiciones de dichos agentes, y metodos de uso.
EP3899024A4 (en) * 2018-12-21 2023-05-31 Ionis Pharmaceuticals, Inc. Modulators of hsd17b13 expression

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