JPWO2023089343A5 - - Google Patents
Info
- Publication number
- JPWO2023089343A5 JPWO2023089343A5 JP2024529771A JP2024529771A JPWO2023089343A5 JP WO2023089343 A5 JPWO2023089343 A5 JP WO2023089343A5 JP 2024529771 A JP2024529771 A JP 2024529771A JP 2024529771 A JP2024529771 A JP 2024529771A JP WO2023089343 A5 JPWO2023089343 A5 JP WO2023089343A5
- Authority
- JP
- Japan
- Prior art keywords
- muscle
- clostridial neurotoxin
- pain
- unit doses
- bont
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2116795.2 | 2021-11-22 | ||
| GB2116774.7 | 2021-11-22 | ||
| GBGB2116795.2A GB202116795D0 (en) | 2021-11-22 | 2021-11-22 | Treatment of visceral pain |
| GBGB2116774.7A GB202116774D0 (en) | 2021-11-22 | 2021-11-22 | Treatment of pain |
| GBGB2206359.8A GB202206359D0 (en) | 2022-04-29 | 2022-04-29 | Treatment of pain |
| GB2206359.8 | 2022-04-29 | ||
| GBPCT/GB2022/052947 | 2022-11-21 | ||
| PCT/GB2022/052947 WO2023089338A1 (en) | 2021-11-22 | 2022-11-21 | Treatment of visceral pain |
| PCT/GB2022/052957 WO2023089343A1 (en) | 2021-11-22 | 2022-11-22 | Treatment of pain |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2024540579A JP2024540579A (ja) | 2024-10-31 |
| JP2024540579A5 JP2024540579A5 (https=) | 2025-12-01 |
| JPWO2023089343A5 true JPWO2023089343A5 (https=) | 2025-12-01 |
Family
ID=84370182
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024529771A Pending JP2024540579A (ja) | 2021-11-22 | 2022-11-22 | 疼痛の治療 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US20260014237A1 (https=) |
| EP (1) | EP4436594A1 (https=) |
| JP (1) | JP2024540579A (https=) |
| KR (1) | KR20240116485A (https=) |
| AU (1) | AU2022392458A1 (https=) |
| CA (1) | CA3234608A1 (https=) |
| WO (1) | WO2023089343A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB202214229D0 (en) | 2022-09-28 | 2022-11-09 | Ipsen Biopharm Ltd | Clostridial neurotoxins comprising an activating endosomal protease cleavage site |
| GB202214232D0 (en) | 2022-09-28 | 2022-11-09 | Ispen Biopharm Ltd | Clostridial neurotoxins comprising an activating exogenous protease cleavage site |
| GB202307439D0 (en) * | 2023-05-18 | 2023-07-05 | Ipsen Biopharm Ltd | Treatment of a headache disorder with botylinum neurotoxin a |
| GB202318884D0 (en) | 2023-12-11 | 2024-01-24 | Ipsen Biopharm Ltd | Formulation |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| IL99552A0 (en) | 1990-09-28 | 1992-08-18 | Ixsys Inc | Compositions containing procaryotic cells,a kit for the preparation of vectors useful for the coexpression of two or more dna sequences and methods for the use thereof |
| DE102004043009A1 (de) | 2004-09-06 | 2006-03-23 | Toxogen Gmbh | Transportprotein zum Einbringen chemischer Verbindungen in Nervenzellen |
| DE102005019302A1 (de) | 2005-04-26 | 2006-11-16 | Toxogen Gmbh | Carrier zum Targeting von Nervenzellen |
| ES2369558T3 (es) | 2005-09-19 | 2011-12-01 | Allergan, Inc. | Toxinas clostridiales y toxinas clostridiales activables. |
| CA2758274C (en) | 2009-04-14 | 2018-04-10 | Mcw Research Foundation, Inc. | Engineered botulinum neurotoxin |
| US8853360B2 (en) | 2010-06-23 | 2014-10-07 | Wisconsin Alumni Research Foundation | Engineered botulinum neurotoxin C1 with selective substrate specificity |
| EP3162894B1 (en) | 2011-05-19 | 2024-01-10 | Ipsen Bioinnovation Limited | Methods for the manufacture of proteolytically processed polypeptides |
| SG10201606666XA (en) | 2012-05-30 | 2016-09-29 | Harvard College | Engineered Botulinum Neurotoxin |
| WO2014079495A1 (en) | 2012-11-21 | 2014-05-30 | Syntaxin Limited | Methods for the manufacture of proteolytically processed polypeptides |
| PT3274364T (pt) | 2015-03-26 | 2021-11-05 | Harvard College | Neurotoxina botulínica manipulada |
| GB201607901D0 (en) * | 2016-05-05 | 2016-06-22 | Ipsen Biopharm Ltd | Chimeric neurotoxins |
| CN109476713A (zh) * | 2016-06-08 | 2019-03-15 | 儿童医学中心公司 | 工程改造的肉毒杆菌神经毒素 |
| EP3481852B1 (en) | 2016-07-08 | 2022-12-07 | Children's Medical Center Corporation | A novel botulinum neurotoxin and its derivatives |
| UA128185C2 (uk) | 2018-01-29 | 2024-05-01 | Іпсен Біофарм Лімітед | Ботулінічний нейротоксин, який розщеплює ненейронний snare |
| GB201914034D0 (en) * | 2019-09-30 | 2019-11-13 | Ipsen Biopharm Ltd | Treatment of neurological disorders |
| BR112022018456A2 (pt) * | 2020-03-16 | 2022-11-01 | Ipsen Biopharm Ltd | Tratamento de espasticidade de membro |
| GB202104294D0 (en) * | 2021-03-26 | 2021-05-12 | Ipsen Biopharm Ltd | Clostridial neurotoxins comprising an exogenous activation loop |
| JP7659653B2 (ja) * | 2021-03-30 | 2025-04-09 | イプセン バイオファーム リミテッド | 疼痛及び炎症性障害の処置 |
| WO2022208091A1 (en) * | 2021-03-30 | 2022-10-06 | Ipsen Biopharm Limited | Treatment of pain & inflammatory disorders |
-
2022
- 2022-11-22 WO PCT/GB2022/052957 patent/WO2023089343A1/en not_active Ceased
- 2022-11-22 EP EP22817312.6A patent/EP4436594A1/en active Pending
- 2022-11-22 KR KR1020247020412A patent/KR20240116485A/ko active Pending
- 2022-11-22 JP JP2024529771A patent/JP2024540579A/ja active Pending
- 2022-11-22 CA CA3234608A patent/CA3234608A1/en active Pending
- 2022-11-22 AU AU2022392458A patent/AU2022392458A1/en active Pending
- 2022-11-22 US US18/711,074 patent/US20260014237A1/en active Pending
-
2025
- 2025-09-26 US US19/342,035 patent/US20260021170A1/en active Pending
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