JPWO2023078946A5 - - Google Patents
Info
- Publication number
- JPWO2023078946A5 JPWO2023078946A5 JP2024525401A JP2024525401A JPWO2023078946A5 JP WO2023078946 A5 JPWO2023078946 A5 JP WO2023078946A5 JP 2024525401 A JP2024525401 A JP 2024525401A JP 2024525401 A JP2024525401 A JP 2024525401A JP WO2023078946 A5 JPWO2023078946 A5 JP WO2023078946A5
- Authority
- JP
- Japan
- Prior art keywords
- compound
- lipid
- lipid nanoparticle
- mol
- concentration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP21205899.4 | 2021-11-02 | ||
| EP21205899 | 2021-11-02 | ||
| PCT/EP2022/080576 WO2023078946A1 (en) | 2021-11-02 | 2022-11-02 | Lipid nanoparticles for oligonucleotide delivery |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2024540101A JP2024540101A (ja) | 2024-10-31 |
| JPWO2023078946A5 true JPWO2023078946A5 (https=) | 2025-10-31 |
| JP2024540101A5 JP2024540101A5 (https=) | 2025-10-31 |
Family
ID=78500458
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024525401A Pending JP2024540101A (ja) | 2021-11-02 | 2022-11-02 | オリゴヌクレオチド送達のための脂質ナノ粒子 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20250073177A1 (https=) |
| EP (2) | EP4613740A3 (https=) |
| JP (1) | JP2024540101A (https=) |
| KR (1) | KR20240099375A (https=) |
| CN (1) | CN118215472A (https=) |
| AU (1) | AU2022381685A1 (https=) |
| CA (1) | CA3236638A1 (https=) |
| DK (1) | DK4426269T3 (https=) |
| ES (1) | ES3048411T3 (https=) |
| FI (1) | FI4426269T3 (https=) |
| IL (1) | IL312431B2 (https=) |
| MX (1) | MX2024005110A (https=) |
| PL (1) | PL4426269T3 (https=) |
| PT (1) | PT4426269T (https=) |
| WO (1) | WO2023078946A1 (https=) |
| ZA (1) | ZA202403337B (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN118125994A (zh) * | 2022-11-25 | 2024-06-04 | 艾斯拓康医药科技(北京)有限公司 | 可离子化脂质及其应用 |
| WO2025088152A1 (en) | 2023-10-27 | 2025-05-01 | Ziphius Nv | MODIFIED 5'UTRs |
| US12599560B2 (en) | 2023-11-02 | 2026-04-14 | Longuide Biopharma Corporation | Lipids and lipid nanoparticle formulations |
| CN117550985B (zh) * | 2023-11-08 | 2025-02-18 | 深圳厚存纳米药业有限公司 | 一种脂质化合物及其用途 |
| WO2025104023A1 (en) | 2023-11-13 | 2025-05-22 | Ziphius Nv | MODIFIED ALPHAVIRAL nsP3 |
| WO2025140594A1 (zh) * | 2023-12-29 | 2025-07-03 | 厦门赛诺邦格生物科技股份有限公司 | 一种含有多级叔胺的不对称阳离子脂质 |
| WO2026046237A1 (zh) * | 2024-08-27 | 2026-03-05 | 北京剂泰生命科技有限公司 | 肺靶向的脂质化合物 |
| CN120943786A (zh) * | 2025-07-17 | 2025-11-14 | 深圳市艾迪贝克生物技术有限公司 | 脂质化合物、其纳米颗粒及应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6451592B1 (en) | 1996-04-05 | 2002-09-17 | Chiron Corporation | Recombinant alphavirus-based vectors with reduced inhibition of cellular macromolecular synthesis |
| EP1751289B1 (en) | 2004-05-18 | 2009-01-14 | Alphavax, Inc. | Tc-83-derived alphavirus vectors, particles and methods |
| US7332322B2 (en) | 2004-09-14 | 2008-02-19 | Ilya Frolov | Venezuelan equine encephalitis virus replicons with adaptive mutations in the genome and uses thereof |
| US8691750B2 (en) * | 2011-05-17 | 2014-04-08 | Axolabs Gmbh | Lipids and compositions for intracellular delivery of biologically active compounds |
| EP2882706A1 (en) * | 2012-08-13 | 2015-06-17 | Massachusetts Institute of Technology | Amine-containing lipidoids and uses thereof |
| US12077501B2 (en) * | 2017-06-14 | 2024-09-03 | Modernatx, Inc. | Compounds and compositions for intracellular delivery of agents |
-
2022
- 2022-11-02 US US18/705,454 patent/US20250073177A1/en active Pending
- 2022-11-02 AU AU2022381685A patent/AU2022381685A1/en active Pending
- 2022-11-02 JP JP2024525401A patent/JP2024540101A/ja active Pending
- 2022-11-02 IL IL312431A patent/IL312431B2/en unknown
- 2022-11-02 DK DK22813503.4T patent/DK4426269T3/da active
- 2022-11-02 PL PL22813503.4T patent/PL4426269T3/pl unknown
- 2022-11-02 PT PT228135034T patent/PT4426269T/pt unknown
- 2022-11-02 FI FIEP22813503.4T patent/FI4426269T3/fi active
- 2022-11-02 ES ES22813503T patent/ES3048411T3/es active Active
- 2022-11-02 EP EP25189030.7A patent/EP4613740A3/en active Pending
- 2022-11-02 WO PCT/EP2022/080576 patent/WO2023078946A1/en not_active Ceased
- 2022-11-02 KR KR1020247018042A patent/KR20240099375A/ko active Pending
- 2022-11-02 CA CA3236638A patent/CA3236638A1/en active Pending
- 2022-11-02 MX MX2024005110A patent/MX2024005110A/es unknown
- 2022-11-02 EP EP22813503.4A patent/EP4426269B1/en active Active
- 2022-11-02 CN CN202280072360.5A patent/CN118215472A/zh active Pending
-
2024
- 2024-04-29 ZA ZA2024/03337A patent/ZA202403337B/en unknown
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