JPWO2023077120A5 - - Google Patents

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Publication number
JPWO2023077120A5
JPWO2023077120A5 JP2024525780A JP2024525780A JPWO2023077120A5 JP WO2023077120 A5 JPWO2023077120 A5 JP WO2023077120A5 JP 2024525780 A JP2024525780 A JP 2024525780A JP 2024525780 A JP2024525780 A JP 2024525780A JP WO2023077120 A5 JPWO2023077120 A5 JP WO2023077120A5
Authority
JP
Japan
Prior art keywords
composition
light chain
seq
antibody
heavy chain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024525780A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024540199A (ja
JP2024540199A5 (https=
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/078975 external-priority patent/WO2023077120A1/en
Publication of JP2024540199A publication Critical patent/JP2024540199A/ja
Publication of JPWO2023077120A5 publication Critical patent/JPWO2023077120A5/ja
Publication of JP2024540199A5 publication Critical patent/JP2024540199A5/ja
Pending legal-status Critical Current

Links

JP2024525780A 2021-11-01 2022-10-31 ジストロフィノパチーを処置するための筋標的化複合体 Pending JP2024540199A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163274306P 2021-11-01 2021-11-01
US63/274,306 2021-11-01
PCT/US2022/078975 WO2023077120A1 (en) 2021-11-01 2022-10-31 Muscle targeting complexes for treating dystrophinopathies

Publications (3)

Publication Number Publication Date
JP2024540199A JP2024540199A (ja) 2024-10-31
JPWO2023077120A5 true JPWO2023077120A5 (https=) 2026-01-19
JP2024540199A5 JP2024540199A5 (https=) 2026-01-19

Family

ID=86158573

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024525780A Pending JP2024540199A (ja) 2021-11-01 2022-10-31 ジストロフィノパチーを処置するための筋標的化複合体

Country Status (9)

Country Link
EP (1) EP4426356A1 (https=)
JP (1) JP2024540199A (https=)
KR (1) KR20240095330A (https=)
CN (1) CN118201640A (https=)
AU (1) AU2022377070A1 (https=)
CA (1) CA3233308A1 (https=)
IL (1) IL312142A (https=)
MX (1) MX2024005332A (https=)
WO (1) WO2023077120A1 (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11168141B2 (en) 2018-08-02 2021-11-09 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating dystrophinopathies
US11911484B2 (en) 2018-08-02 2024-02-27 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating myotonic dystrophy
EP3829595A4 (en) 2018-08-02 2022-08-24 Dyne Therapeutics, Inc. MUSCLE-DIRECTED COMPLEXES AND USES THEREOF IN THE TREATMENT OF DYSTROPHINOPATHIES
US12018087B2 (en) 2018-08-02 2024-06-25 Dyne Therapeutics, Inc. Muscle-targeting complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and methods of delivering oligonucleotide to a subject
US12370264B1 (en) 2018-08-02 2025-07-29 Dyne Therapeutics, Inc. Complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and method of delivering oligonucleotide to a subject
US20220193250A1 (en) 2018-08-02 2022-06-23 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy
US12097263B2 (en) 2018-08-02 2024-09-24 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating myotonic dystrophy
US11638761B2 (en) 2021-07-09 2023-05-02 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating Facioscapulohumeral muscular dystrophy
US11771776B2 (en) 2021-07-09 2023-10-03 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating dystrophinopathies
IL309936A (en) 2021-07-09 2024-03-01 Dyne Therapeutics Inc Muscle targeting complexes and formulations for the treatment of dystrophinopathy
US11969475B2 (en) 2021-07-09 2024-04-30 Dyne Therapeutics, Inc. Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy
US20250339553A1 (en) 2022-04-15 2025-11-06 Dyne Therapeutics, Inc. Muscle targeting complexes and formulations for treating myotonic dystrophy

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012007896A1 (en) * 2010-07-12 2012-01-19 Covx Technologies Ireland, Ltd. Multifunctional antibody conjugates
TW201341401A (zh) * 2012-01-09 2013-10-16 Covx Technologies Ireland Ltd 突變抗體及其共軛
WO2016205641A2 (en) * 2015-06-17 2016-12-22 Research Institute At Nationwide Children's Hospital Respiratory syncytial virus having cleavage-resistant g protein and related materials and methods
TWI737736B (zh) * 2016-05-24 2021-09-01 美商薩羅塔治療公司 製備磷醯二胺嗎啉代寡聚物之方法
JP7073487B2 (ja) * 2017-06-16 2022-05-23 イーライ リリー アンド カンパニー 操作された抗体化合物およびこれらの抱合体
KR20220125801A (ko) * 2020-01-10 2022-09-14 다인 세라퓨틱스, 인크. 근육 표적화 복합체 및 안면견갑상완 근육 이영양증을 치료하기 위한 그의 용도

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