JPWO2023049477A5 - - Google Patents
Info
- Publication number
- JPWO2023049477A5 JPWO2023049477A5 JP2024518725A JP2024518725A JPWO2023049477A5 JP WO2023049477 A5 JPWO2023049477 A5 JP WO2023049477A5 JP 2024518725 A JP2024518725 A JP 2024518725A JP 2024518725 A JP2024518725 A JP 2024518725A JP WO2023049477 A5 JPWO2023049477 A5 JP WO2023049477A5
- Authority
- JP
- Japan
- Prior art keywords
- oligonucleotide
- nucleic acid
- target nucleic
- composition
- target
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163248524P | 2021-09-26 | 2021-09-26 | |
| US63/248,524 | 2021-09-26 | ||
| US202263341391P | 2022-05-12 | 2022-05-12 | |
| US63/341,391 | 2022-05-12 | ||
| PCT/US2022/044767 WO2023049477A2 (en) | 2021-09-26 | 2022-09-26 | Compositions for editing mecp2 transcripts and methods thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2024536088A JP2024536088A (ja) | 2024-10-04 |
| JPWO2023049477A5 true JPWO2023049477A5 (https=) | 2025-10-06 |
| JP2024536088A5 JP2024536088A5 (https=) | 2025-10-06 |
Family
ID=85721202
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024518725A Pending JP2024536088A (ja) | 2021-09-26 | 2022-09-26 | Ｍｅｃｐ２転写物を編集するための組成物及びその方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20250135036A1 (https=) |
| EP (1) | EP4404942A2 (https=) |
| JP (1) | JP2024536088A (https=) |
| AU (1) | AU2022349529A1 (https=) |
| CA (1) | CA3232965A1 (https=) |
| WO (1) | WO2023049477A2 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG11201500239VA (en) | 2012-07-13 | 2015-03-30 | Wave Life Sciences Japan | Asymmetric auxiliary group |
| ES2917473T3 (es) | 2014-01-16 | 2022-07-08 | Wave Life Sciences Ltd | Diseño quiral |
| CN108135921B (zh) | 2015-07-22 | 2023-10-17 | 波涛生命科学有限公司 | 寡核苷酸组合物及其方法 |
| CN109562122A (zh) | 2016-06-03 | 2019-04-02 | 波涛生命科学有限公司 | 寡核苷酸、组合物及其方法 |
| MA46905A (fr) | 2016-11-23 | 2019-10-02 | Wave Life Sciences Ltd | Compositions et procédés de synthèse de phosphoramidites et d'oligonucléotides |
| US11718638B2 (en) | 2017-06-21 | 2023-08-08 | Wave Life Sciences Ltd. | Compounds, compositions and methods for synthesis |
| CN111108096A (zh) | 2017-09-18 | 2020-05-05 | 波涛生命科学有限公司 | 寡核苷酸制备技术 |
| IL277889B2 (en) | 2018-04-12 | 2025-01-01 | Wave Life Sciences Ltd | Oligonucleotide preparations and methods of using them |
| EP3790596A4 (en) | 2018-05-11 | 2022-04-06 | Wave Life Sciences Ltd. | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE |
| CN113748116A (zh) | 2019-03-20 | 2021-12-03 | 波涛生命科学有限公司 | 可用于寡核苷酸制备的技术 |
| AU2024354150A1 (en) * | 2023-09-28 | 2026-03-12 | Wave Life Sciences Ltd. | Oligonucleotide compositions and methods thereof |
| WO2026077951A1 (en) | 2024-10-07 | 2026-04-16 | Vico Therapeutics B.V. | Improved aon for rna editing |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030190626A1 (en) * | 2002-04-09 | 2003-10-09 | Vasulinga Ravikumar | Phosphorothioate monoester modified oligomers |
| WO2018213708A1 (en) * | 2017-05-18 | 2018-11-22 | The Broad Institute, Inc. | Systems, methods, and compositions for targeted nucleic acid editing |
| US20220387622A1 (en) * | 2019-05-21 | 2022-12-08 | Beam Therapeutics Inc. | Methods of editing a single nucleotide polymorphism using programmable base editor systems |
| EP4240849A4 (en) * | 2020-11-08 | 2026-04-01 | Wave Life Sciences Ltd | OLIGONUCLEOTIDE COMPOSITIONS AND ASSOCIATED PROCESSES |
-
2022
- 2022-09-26 JP JP2024518725A patent/JP2024536088A/ja active Pending
- 2022-09-26 EP EP22873722.7A patent/EP4404942A2/en active Pending
- 2022-09-26 WO PCT/US2022/044767 patent/WO2023049477A2/en not_active Ceased
- 2022-09-26 AU AU2022349529A patent/AU2022349529A1/en active Pending
- 2022-09-26 CA CA3232965A patent/CA3232965A1/en active Pending
- 2022-09-26 US US18/695,348 patent/US20250135036A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JPWO2022099159A5 (https=) | ||
| CN113994000B (zh) | 包括胞苷类似物的反义rna编辑寡核苷酸 | |
| JPWO2023049477A5 (https=) | ||
| CN113329739B (zh) | 用于治疗scn1a脑病的靶向scn2a的反义寡核苷酸 | |
| JP2023535918A (ja) | Ｒｎａ編集用のアンチセンスオリゴヌクレオチド | |
| US6221850B1 (en) | Antisense oligonucleotide compositions and methods for the modulation of JNK proteins | |
| IL302558A (en) | Oligonucleotide compositions and methods thereof | |
| JPWO2021071788A5 (https=) | ||
| US20200172564A1 (en) | Stabilized Nucleic Acids Encoding Messenger Ribonucleic Acid (mRNA) | |
| JPWO2020227691A5 (https=) | ||
| HK1255699A1 (zh) | Kras表达的调节剂 | |
| CN108410868A (zh) | Gcgr表达的反义调节 | |
| CN105121452A (zh) | 三环核苷和由其制备的寡聚化合物 | |
| CN116322707B (zh) | 用于调节scn2a的化合物和方法 | |
| KR20150004414A (ko) | Kras-관련 질환을 치료하기 위한 유기 조성물 | |
| EP3471781A1 (en) | Modulation of gys1 expression | |
| US20230235329A1 (en) | Antisense oligonucleotides (aso) for efficient and precise rna editing with endogenous adenosine deaminase acting on rna (adar) | |
| JP2025503034A (ja) | 補体因子ｂを阻害するための組成物及び方法 | |
| WO2019181946A1 (ja) | 毒性が軽減した核酸 | |
| KR20200104347A (ko) | 포스포로디티오에이트 인터뉴클레오시드 연결을 포함하는 갭머 올리고뉴클레오티드 | |
| JP2024515344A (ja) | 補体成分３の発現を阻害するための組成物及び方法 | |
| TW202020155A (zh) | 含有三硫代磷酸酯核苷間連結之寡核苷酸 | |
| US20210290653A1 (en) | Modulation of lnc05 expression | |
| WO2019044974A1 (ja) | スモールガイドアンチセンス核酸とその使用 | |
| CN115103911A (zh) | 修饰的异源核酸 |