JPWO2023002045A5 - - Google Patents
Info
- Publication number
- JPWO2023002045A5 JPWO2023002045A5 JP2024503606A JP2024503606A JPWO2023002045A5 JP WO2023002045 A5 JPWO2023002045 A5 JP WO2023002045A5 JP 2024503606 A JP2024503606 A JP 2024503606A JP 2024503606 A JP2024503606 A JP 2024503606A JP WO2023002045 A5 JPWO2023002045 A5 JP WO2023002045A5
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- pharmaceutically acceptable
- disease
- group
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP21187424.3A EP4122499A1 (en) | 2021-07-23 | 2021-07-23 | Fibroblast activation protein inhibitors and use thereof |
| EP21187424.3 | 2021-07-23 | ||
| PCT/EP2022/070693 WO2023002045A1 (en) | 2021-07-23 | 2022-07-22 | Fibroblast activation protein inhibitors and use thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2024527627A JP2024527627A (ja) | 2024-07-25 |
| JP2024527627A5 JP2024527627A5 (https=) | 2026-01-30 |
| JPWO2023002045A5 true JPWO2023002045A5 (https=) | 2026-01-30 |
Family
ID=77042830
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024503606A Pending JP2024527627A (ja) | 2021-07-23 | 2022-07-22 | 線維芽細胞活性化タンパク質阻害剤及びその使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20240335569A1 (https=) |
| EP (2) | EP4122499A1 (https=) |
| JP (1) | JP2024527627A (https=) |
| KR (1) | KR20240040092A (https=) |
| CN (1) | CN117769443A (https=) |
| AU (1) | AU2022313521A1 (https=) |
| CA (1) | CA3224514A1 (https=) |
| CL (1) | CL2024000200A1 (https=) |
| IL (1) | IL310306A (https=) |
| MX (1) | MX2024000866A (https=) |
| WO (1) | WO2023002045A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4475900A1 (en) | 2022-02-09 | 2024-12-18 | Novartis AG | Pharmaceutical compositions comprising a 225-actinium-labelled complex and a bismuth sequestering agent |
| EP4342890A1 (en) * | 2022-09-21 | 2024-03-27 | Erasmus University Rotterdam Medical Center | Platform and scaffold for fap targeting agents |
| WO2025106939A1 (en) * | 2023-11-16 | 2025-05-22 | Praxis Biotech LLC | Conjugates targeting fibroblast activation protein and uses thereof |
| CN119604492A (zh) * | 2023-12-08 | 2025-03-11 | 北京师范大学 | 一种放射性标记fapi配合物及其制备方法和应用 |
| WO2025167951A1 (zh) * | 2024-02-07 | 2025-08-14 | 苏州博锐创合医药有限公司 | 一种成纤维细胞活化蛋白抑制剂 |
| WO2025240871A1 (en) * | 2024-05-16 | 2025-11-20 | Purdue Research Foundation | Chemically stable keto-amide-based fibroblast activation protein-targeted nanoparticle-based magnetic resonance imaging agent, compositions, and methods of use |
| CN118978511A (zh) * | 2024-08-02 | 2024-11-19 | 江苏华益科技有限公司 | 一种靶向fap化合物及其制备方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4885363A (en) | 1987-04-24 | 1989-12-05 | E. R. Squibb & Sons, Inc. | 1-substituted-1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclododecane and analogs |
| US5021556A (en) | 1987-07-22 | 1991-06-04 | Neorx Corporation | Method of radiolabeling chelating compounds comprising sulfur atoms with metal radionuclides |
| US5075099A (en) | 1988-05-31 | 1991-12-24 | Neorx Corporation | Metal radionuclide chelating compounds for improved chelation kinetics |
| US5364613A (en) | 1989-04-07 | 1994-11-15 | Sieving Paul F | Polychelants containing macrocyclic chelant moieties |
| US5367080A (en) | 1990-11-08 | 1994-11-22 | Sterling Winthrop Inc. | Complexing agents and targeting radioactive immunoreagents useful in therapeutic and diagnostic imaging compositions and methods |
| US5965107A (en) | 1992-03-13 | 1999-10-12 | Diatide, Inc. | Technetium-99m labeled peptides for imaging |
| US5886142A (en) | 1997-05-20 | 1999-03-23 | Thomas Jefferson University | Radiolabeled thrombus imaging agents |
| CN103370063A (zh) | 2010-12-13 | 2013-10-23 | 免疫医疗公司 | 用于改善蛋白质、肽和其他分子的f-18标记的方法和组合物 |
| DE102014115088A1 (de) | 2014-10-16 | 2016-04-21 | Sovicell Gmbh | Bestimmung von Bindungskonstanten mittels Gleichgewichtsverlagerung |
| EA202090776A1 (ru) * | 2017-10-23 | 2020-07-27 | Дзе Джонс Хопкинс Юниверсити | Визуализирующие и радиотерапевтические агенты, нацеленные на фибробласт-активирующий белок-альфа (fapalpha) |
| SG11202007180QA (en) * | 2018-02-06 | 2020-08-28 | Univ Heidelberg | Fap inhibitor |
| DE102018126558A1 (de) * | 2018-10-24 | 2020-04-30 | Helmholtz-Zentrum Dresden - Rossendorf E.V. | Markierungsvorläufer mit Quadratsäure-Kopplung |
| CN113811529A (zh) * | 2018-12-21 | 2021-12-17 | 普拉西斯生物技术有限责任公司 | 成纤维细胞激活蛋白抑制剂 |
-
2021
- 2021-07-23 EP EP21187424.3A patent/EP4122499A1/en not_active Ceased
-
2022
- 2022-07-22 WO PCT/EP2022/070693 patent/WO2023002045A1/en not_active Ceased
- 2022-07-22 AU AU2022313521A patent/AU2022313521A1/en active Pending
- 2022-07-22 MX MX2024000866A patent/MX2024000866A/es unknown
- 2022-07-22 CN CN202280050775.2A patent/CN117769443A/zh active Pending
- 2022-07-22 IL IL310306A patent/IL310306A/en unknown
- 2022-07-22 JP JP2024503606A patent/JP2024527627A/ja active Pending
- 2022-07-22 CA CA3224514A patent/CA3224514A1/en active Pending
- 2022-07-22 EP EP22757517.2A patent/EP4373529A1/en active Pending
- 2022-07-22 KR KR1020247005694A patent/KR20240040092A/ko active Pending
- 2022-07-22 US US18/291,078 patent/US20240335569A1/en active Pending
-
2024
- 2024-01-23 CL CL2024000200A patent/CL2024000200A1/es unknown
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