JPWO2022266032A5 - - Google Patents
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- Publication number
- JPWO2022266032A5 JPWO2022266032A5 JP2023577160A JP2023577160A JPWO2022266032A5 JP WO2022266032 A5 JPWO2022266032 A5 JP WO2022266032A5 JP 2023577160 A JP2023577160 A JP 2023577160A JP 2023577160 A JP2023577160 A JP 2023577160A JP WO2022266032 A5 JPWO2022266032 A5 JP WO2022266032A5
- Authority
- JP
- Japan
- Prior art keywords
- lipid
- alkyl
- pharma
- acceptable salt
- ceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163210204P | 2021-06-14 | 2021-06-14 | |
| US63/210,204 | 2021-06-14 | ||
| PCT/US2022/033334 WO2022266032A1 (en) | 2021-06-14 | 2022-06-14 | Cationic lipids and compositions thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2024522692A JP2024522692A (ja) | 2024-06-21 |
| JP2024522692A5 JP2024522692A5 (https=) | 2025-06-24 |
| JPWO2022266032A5 true JPWO2022266032A5 (https=) | 2025-06-24 |
Family
ID=82547431
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023577160A Pending JP2024522692A (ja) | 2021-06-14 | 2022-06-14 | カチオン性脂質及びその組成物 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20240293574A1 (https=) |
| EP (1) | EP4355727A1 (https=) |
| JP (1) | JP2024522692A (https=) |
| KR (1) | KR20240023420A (https=) |
| CN (1) | CN117642380A (https=) |
| AU (1) | AU2022291742A1 (https=) |
| CA (1) | CA3222589A1 (https=) |
| IL (1) | IL309145A (https=) |
| MX (1) | MX2023014855A (https=) |
| WO (1) | WO2022266032A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116082184B (zh) * | 2023-04-12 | 2023-06-30 | 山东大学 | 基于环己二胺的可电离脂质、脂质纳米颗粒及其制备方法与应用 |
| US12311033B2 (en) | 2023-05-31 | 2025-05-27 | Capstan Therapeutics, Inc. | Lipid nanoparticle formulations and compositions |
| KR102898792B1 (ko) * | 2023-06-26 | 2025-12-19 | 주식회사 무진메디 | 이온화 가능한 펩타이드를 이용한 지질 나노입자 기반 약물 전달체 및 이의 제조방법 |
| WO2025005632A1 (ko) * | 2023-06-26 | 2025-01-02 | 주식회사 무진메디 | 이온화 가능한 펩타이드를 이용한 지질 나노입자 기반 약물 전달체 및 이의 제조방법 |
| KR20250106223A (ko) * | 2023-12-29 | 2025-07-09 | 주식회사 삼양홀딩스 | 약물전달용 나노입자의 조성물 |
| CN117964577B (zh) * | 2024-03-29 | 2024-06-21 | 天津全和诚生物技术有限公司 | 阳离子脂质化合物、其制备方法、包含其的组合物及应用 |
| WO2026003582A2 (en) | 2024-06-27 | 2026-01-02 | Axelyf ehf. | Lipids and lipid nanoparticles |
| CN118634207B (zh) * | 2024-08-15 | 2024-11-26 | 北京悦康科创医药科技股份有限公司 | 一种雾化吸入用核酸-脂质纳米粒及其制备方法和应用 |
| CN118903476B (zh) * | 2024-10-10 | 2025-05-06 | 嘉晨西海(南昌)生物制药有限公司 | 含LNP和mRNA的组合物及其在治疗戈谢病中的应用 |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US5885613A (en) | 1994-09-30 | 1999-03-23 | The University Of British Columbia | Bilayer stabilizing components and their use in forming programmable fusogenic liposomes |
| US5928906A (en) | 1996-05-09 | 1999-07-27 | Sequenom, Inc. | Process for direct sequencing during template amplification |
| CA2289702C (en) | 1997-05-14 | 2008-02-19 | Inex Pharmaceuticals Corp. | High efficiency encapsulation of charged therapeutic agents in lipid vesicles |
| US7201898B2 (en) | 2000-06-01 | 2007-04-10 | The University Of North Carolina At Chapel Hill | Methods and compounds for controlled release of recombinant parvovirus vectors |
| US20030077829A1 (en) | 2001-04-30 | 2003-04-24 | Protiva Biotherapeutics Inc.. | Lipid-based formulations |
| US7901708B2 (en) | 2002-06-28 | 2011-03-08 | Protiva Biotherapeutics, Inc. | Liposomal apparatus and manufacturing methods |
| NZ592917A (en) | 2003-09-15 | 2012-12-21 | Protiva Biotherapeutics Inc | Stable polyethyleneglycol (PEG) dialkyloxypropyl (DAA) lipid conjugates |
| US7404969B2 (en) | 2005-02-14 | 2008-07-29 | Sirna Therapeutics, Inc. | Lipid nanoparticle based compositions and methods for the delivery of biologically active molecules |
| US9005654B2 (en) | 2005-07-27 | 2015-04-14 | Protiva Biotherapeutics, Inc. | Systems and methods for manufacturing liposomes |
| US20100015218A1 (en) | 2007-02-16 | 2010-01-21 | Vasant Jadhav | Compositions and methods for potentiated activity of biologically active molecules |
| WO2009086558A1 (en) | 2008-01-02 | 2009-07-09 | Tekmira Pharmaceuticals Corporation | Improved compositions and methods for the delivery of nucleic acids |
| AU2009238175C1 (en) | 2008-04-15 | 2023-11-30 | Arbutus Biopharma Corporation | Novel lipid formulations for nucleic acid delivery |
| EP2558074B1 (en) | 2010-04-08 | 2018-06-06 | The Trustees of Princeton University | Preparation of lipid nanoparticles |
| WO2011139911A2 (en) | 2010-04-29 | 2011-11-10 | Isis Pharmaceuticals, Inc. | Lipid formulated single stranded rna |
| EA201390145A1 (ru) | 2010-08-20 | 2013-11-29 | Серулин Фарма Инк. | Конъюгаты, частицы, композиции и связанные с ними способы |
| CA2853685C (en) | 2011-11-04 | 2019-09-03 | Nitto Denko Corporation | Single use system for sterilely producing lipid-nucleic acid particles |
| AR090906A1 (es) | 2012-05-02 | 2014-12-17 | Merck Sharp & Dohme | Conjugados que contienen tetragalnac y procedimientos para la administracion de oligonucleotidos |
| CN105085292B (zh) * | 2014-05-23 | 2017-12-15 | 上海交通大学 | 3‑((2‑(二甲氨基)乙烷基)(甲基)氨基)丙酸的两亲性衍生物及其用途 |
| LT3313829T (lt) | 2015-06-29 | 2024-08-12 | Acuitas Therapeutics Inc. | Lipidai ir lipidų nanodalelių sudėtys, skirtos nukleorūgščių tiekimui |
| EP4286012A3 (en) | 2015-09-17 | 2024-05-29 | ModernaTX, Inc. | Compounds and compositions for intracellular delivery of therapeutic agents |
| IL307179A (en) | 2015-10-28 | 2023-11-01 | Acuitas Therapeutics Inc | Novel lipids and lipid nanoparticle formulations for delivery of nucleic acids |
| MX378999B (es) | 2015-11-16 | 2025-03-10 | Hoffmann La Roche | Fosforamidita de agrupacion de n-acetilgalactosamina (galnac). |
| HRP20220652T1 (hr) | 2015-12-10 | 2022-06-24 | Modernatx, Inc. | Pripravci i postupci unosa terapijskih sredstava |
| EP3458474B1 (en) * | 2016-05-18 | 2022-07-06 | ModernaTX, Inc. | Combinations of mrnas encoding immune modulating polypeptides and uses thereof |
| MA45036A (fr) * | 2016-05-18 | 2019-03-27 | Modernatx Inc | Polynucléotides codant pour la citrine pour le traitement de la citrullinémie de type 2 |
| SMT202300097T1 (it) * | 2017-03-15 | 2023-05-12 | Modernatx Inc | Composto e composizioni per il rilascio intracellulare di agenti terapeutici |
| JP7630904B2 (ja) * | 2019-07-23 | 2025-02-18 | 株式会社東芝 | 核酸導入キャリア、核酸導入キャリアセット、核酸導入組成物及び核酸導入方法 |
| JP7700101B2 (ja) * | 2019-09-06 | 2025-06-30 | ジェネレーション バイオ カンパニー | 閉端ｄｎａおよび切断可能脂質を含む脂質ナノ粒子組成物ならびにそれらの使用方法 |
| CN114641251A (zh) * | 2019-11-05 | 2022-06-17 | 替代外科手术公司 | 外科手术虚拟现实用户接口 |
| AU2020385378A1 (en) * | 2019-11-22 | 2022-04-07 | Generation Bio Co. | Ionizable lipids and nanoparticle compositions thereof |
| KR20230034333A (ko) * | 2020-07-02 | 2023-03-09 | 라이프 테크놀로지스 코포레이션 | 트리뉴클레오티드 캡 유사체, 제조 및 이의 용도 |
| MX2023000806A (es) * | 2020-07-17 | 2023-04-11 | Generation Bio Co | Métodos para encapsular polinucleótidos en tamaños reducidos de nanopartículas lipídicas y formulación novedosa de estos. |
-
2022
- 2022-06-14 WO PCT/US2022/033334 patent/WO2022266032A1/en not_active Ceased
- 2022-06-14 CN CN202280049199.XA patent/CN117642380A/zh active Pending
- 2022-06-14 US US18/569,623 patent/US20240293574A1/en active Pending
- 2022-06-14 IL IL309145A patent/IL309145A/en unknown
- 2022-06-14 AU AU2022291742A patent/AU2022291742A1/en active Pending
- 2022-06-14 KR KR1020247001308A patent/KR20240023420A/ko active Pending
- 2022-06-14 JP JP2023577160A patent/JP2024522692A/ja active Pending
- 2022-06-14 MX MX2023014855A patent/MX2023014855A/es unknown
- 2022-06-14 EP EP22741620.3A patent/EP4355727A1/en active Pending
- 2022-06-14 CA CA3222589A patent/CA3222589A1/en active Pending
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