JPWO2022251292A5 - - Google Patents
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- Publication number
- JPWO2022251292A5 JPWO2022251292A5 JP2023572737A JP2023572737A JPWO2022251292A5 JP WO2022251292 A5 JPWO2022251292 A5 JP WO2022251292A5 JP 2023572737 A JP2023572737 A JP 2023572737A JP 2023572737 A JP2023572737 A JP 2023572737A JP WO2022251292 A5 JPWO2022251292 A5 JP WO2022251292A5
- Authority
- JP
- Japan
- Prior art keywords
- optionally substituted
- membered
- alkyl
- hydrogen
- cycloalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163192837P | 2021-05-25 | 2021-05-25 | |
| US63/192,837 | 2021-05-25 | ||
| PCT/US2022/030823 WO2022251292A1 (en) | 2021-05-25 | 2022-05-25 | Methods for inhibiting ras |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2024521774A JP2024521774A (ja) | 2024-06-04 |
| JP2024521774A5 JP2024521774A5 (https=) | 2025-06-02 |
| JPWO2022251292A5 true JPWO2022251292A5 (https=) | 2025-06-02 |
Family
ID=82115695
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023572737A Pending JP2024521774A (ja) | 2021-05-25 | 2022-05-25 | Ｒａｓの阻害方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20240277796A1 (https=) |
| EP (1) | EP4346898A1 (https=) |
| JP (1) | JP2024521774A (https=) |
| KR (1) | KR20240026526A (https=) |
| CN (2) | CN118557730A (https=) |
| AU (1) | AU2022281343A1 (https=) |
| CA (1) | CA3219533A1 (https=) |
| IL (1) | IL308771A (https=) |
| MX (1) | MX2023013912A (https=) |
| TW (1) | TW202313631A (https=) |
| WO (1) | WO2022251292A1 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2022005359A (es) | 2019-11-04 | 2022-06-02 | Revolution Medicines Inc | Inhibidores de ras. |
| MX2023003060A (es) | 2020-09-15 | 2023-04-05 | Revolution Medicines Inc | Derivados indolicos como inhibidores de ras en el tratamiento del cancer. |
| AU2022268962A1 (en) | 2021-05-05 | 2023-12-14 | Revolution Medicines, Inc. | Ras inhibitors for the treatment of cancer |
| AR127308A1 (es) * | 2021-10-08 | 2024-01-10 | Revolution Medicines Inc | Inhibidores ras |
| CN118922423A (zh) * | 2022-01-10 | 2024-11-08 | 锐新医药公司 | Ras抑制剂 |
| CN119301132A (zh) * | 2022-06-01 | 2025-01-10 | 豪夫迈·罗氏有限公司 | 用于治疗癌症的卤代吲哚大环化合物 |
| CN119522225A (zh) | 2022-09-29 | 2025-02-25 | 广州嘉越医药科技有限公司 | 大环衍生物及其应用 |
| CR20250329A (es) | 2023-02-14 | 2025-09-12 | Hoffmann La Roche | Compuestos tricíclicos para el tratamiento del cáncer |
| EP4687905A1 (en) * | 2023-03-30 | 2026-02-11 | Revolution Medicines, Inc. | Compositions for inducing ras gtp hydrolysis and uses thereof |
| TW202446387A (zh) * | 2023-04-06 | 2024-12-01 | 瑞士商赫孚孟拉羅股份公司 | 用於治療癌症之三環化合物 |
| AU2024265078A1 (en) | 2023-05-04 | 2025-12-11 | Revolution Medicines, Inc. | Combination therapy for a ras related disease or disorder |
| WO2025019318A2 (en) * | 2023-07-14 | 2025-01-23 | Revolution Medicines, Inc. | Methods of treating a ras related disease or disorder |
| WO2025162395A1 (zh) * | 2024-02-01 | 2025-08-07 | 山东先声生物制药有限公司 | 吲哚衍生物作为ras抑制剂及其应用 |
| CN119431325A (zh) * | 2024-10-31 | 2025-02-14 | 诚达药业股份有限公司 | 一种3-（1h-吡唑-1-基）氮杂环丁烷类化合物及其合成方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20210116479A (ko) | 2018-12-21 | 2021-09-27 | 레볼루션 메디슨즈, 인크. | 공동 결합에 참여하는 화합물 및 그의 용도 |
| DE102019122206B4 (de) | 2019-08-19 | 2021-07-08 | Webasto SE | Dachmodul zur Bildung eines Fahrzeugdachs mit Umfeldsensor |
| MX2022005359A (es) | 2019-11-04 | 2022-06-02 | Revolution Medicines Inc | Inhibidores de ras. |
| CN120699039A (zh) | 2019-11-04 | 2025-09-26 | 锐新医药公司 | Ras抑制剂 |
| WO2021091956A1 (en) | 2019-11-04 | 2021-05-14 | Revolution Medicines, Inc. | Ras inhibitors |
| MX2023003060A (es) | 2020-09-15 | 2023-04-05 | Revolution Medicines Inc | Derivados indolicos como inhibidores de ras en el tratamiento del cancer. |
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2022
- 2022-05-25 MX MX2023013912A patent/MX2023013912A/es unknown
- 2022-05-25 CN CN202410561373.XA patent/CN118557730A/zh active Pending
- 2022-05-25 EP EP22731928.2A patent/EP4346898A1/en active Pending
- 2022-05-25 CA CA3219533A patent/CA3219533A1/en active Pending
- 2022-05-25 JP JP2023572737A patent/JP2024521774A/ja active Pending
- 2022-05-25 KR KR1020237044138A patent/KR20240026526A/ko active Pending
- 2022-05-25 AU AU2022281343A patent/AU2022281343A1/en active Pending
- 2022-05-25 IL IL308771A patent/IL308771A/en unknown
- 2022-05-25 TW TW111119516A patent/TW202313631A/zh unknown
- 2022-05-25 CN CN202280050079.1A patent/CN117715658A/zh active Pending
- 2022-05-25 WO PCT/US2022/030823 patent/WO2022251292A1/en not_active Ceased
-
2023
- 2023-11-22 US US18/518,027 patent/US20240277796A1/en active Pending