JPWO2022236050A5 - - Google Patents

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Publication number
JPWO2022236050A5
JPWO2022236050A5 JP2023568469A JP2023568469A JPWO2022236050A5 JP WO2022236050 A5 JPWO2022236050 A5 JP WO2022236050A5 JP 2023568469 A JP2023568469 A JP 2023568469A JP 2023568469 A JP2023568469 A JP 2023568469A JP WO2022236050 A5 JPWO2022236050 A5 JP WO2022236050A5
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JP
Japan
Prior art keywords
seq
amino acid
polypeptide chain
nos
acid sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023568469A
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English (en)
Japanese (ja)
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JP2024517884A (ja
JP2024517884A5 (https=
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Application filed filed Critical
Priority claimed from PCT/US2022/028066 external-priority patent/WO2022236050A1/en
Publication of JP2024517884A publication Critical patent/JP2024517884A/ja
Publication of JP2024517884A5 publication Critical patent/JP2024517884A5/ja
Publication of JPWO2022236050A5 publication Critical patent/JPWO2022236050A5/ja
Pending legal-status Critical Current

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JP2023568469A 2021-05-07 2022-05-06 p53におけるC135Y、R175H又はM237I変異を認識するT細胞受容体 Pending JP2024517884A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163185805P 2021-05-07 2021-05-07
US63/185,805 2021-05-07
PCT/US2022/028066 WO2022236050A1 (en) 2021-05-07 2022-05-06 T cell receptors recognizing c135y, r175h, or m237i mutation in p53

Publications (3)

Publication Number Publication Date
JP2024517884A JP2024517884A (ja) 2024-04-23
JP2024517884A5 JP2024517884A5 (https=) 2025-05-20
JPWO2022236050A5 true JPWO2022236050A5 (https=) 2025-05-20

Family

ID=81851071

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023568469A Pending JP2024517884A (ja) 2021-05-07 2022-05-06 p53におけるC135Y、R175H又はM237I変異を認識するT細胞受容体

Country Status (8)

Country Link
US (1) US20240254190A1 (https=)
EP (1) EP4334340A1 (https=)
JP (1) JP2024517884A (https=)
KR (1) KR20240016288A (https=)
CN (1) CN117957245A (https=)
AU (1) AU2022268998A1 (https=)
CA (1) CA3217263A1 (https=)
WO (1) WO2022236050A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3144070A1 (en) 2019-06-27 2020-12-30 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services T cell receptors recognizing r175h or y220c mutation in p53
US12195534B2 (en) 2023-01-06 2025-01-14 Immunocore Limited Binding molecules
WO2024163371A1 (en) * 2023-01-30 2024-08-08 Fred Hutchinson Cancer Center Binding proteins specific for mutant p53 and uses thereof
WO2024206274A2 (en) * 2023-03-27 2024-10-03 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services T cell receptors targeting y220c or r175h mutation in p53
WO2025024648A2 (en) * 2023-07-25 2025-01-30 Memorial Sloan-Kettering Cancer Center T cell receptors targeting tp53 hotspot mutations and uses thereof

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003265948B8 (en) 2002-09-06 2009-09-03 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Immunotherapy with in vitro-selected antigen-specific lymphocytes after nonmyeloablative lymphodepleting chemotherapy
US8383099B2 (en) 2009-08-28 2013-02-26 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Adoptive cell therapy with young T cells
WO2012129201A1 (en) 2011-03-22 2012-09-27 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Methods of growing tumor infiltrating lymphocytes in gas-permeable containers
US11390921B2 (en) * 2014-04-01 2022-07-19 Adaptive Biotechnologies Corporation Determining WT-1 specific T cells and WT-1 specific T cell receptors (TCRs)
IL290655B2 (en) 2014-05-29 2024-05-01 Us Health Anti-human papillomavirus 16 E7 T-cell chelates
CA3080274A1 (en) * 2017-09-29 2019-04-04 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Methods of isolating t cells having antigenic specificity for a p53 cancer-specific mutation
EA202090757A1 (ru) * 2017-09-29 2020-08-21 Дзе Юнайтед Стейтс Оф Америка, Эз Репрезентед Бай Дзе Секретари, Департмент Оф Хелс Энд Хьюман Сёрвисез T-КЛЕТОЧНЫЕ РЕЦЕПТОРЫ, РАСПОЗНАЮЩИЕ МУТАНТНЫЙ p53
US20220175899A1 (en) * 2019-04-11 2022-06-09 The Board Of Trustees Of The Leland Stanford Junior University Cytotoxic t lymphocytes specific for mutated forms of epidermal growth factor receptor for use in treating cancer
CA3144070A1 (en) * 2019-06-27 2020-12-30 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services T cell receptors recognizing r175h or y220c mutation in p53

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