JPWO2022221143A5 - - Google Patents

Info

Publication number

JPWO2022221143A5

JPWO2022221143A5 JP2023562607A JP2023562607A JPWO2022221143A5 JP WO2022221143 A5 JPWO2022221143 A5 JP WO2022221143A5 JP 2023562607 A JP2023562607 A JP 2023562607A JP 2023562607 A JP2023562607 A JP 2023562607A JP WO2022221143 A5 JPWO2022221143 A5 JP WO2022221143A5

Authority

JP

Japan

Prior art keywords

pharmaceutical composition

subject

effective amount

therapeutically effective

administered

Prior art date

2025-04-09

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

Links

• Espacenet
• Global Dossier
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• 239000008194 pharmaceutical composition Substances 0.000 claims 16
• 229940126117 ZN-c3 Drugs 0.000 claims 10
• 208000018463 endometrial serous adenocarcinoma Diseases 0.000 claims 7
• AOJJSUZBOXZQNB-TZSSRYMLSA-N Doxorubicin Chemical compound O([C@H]1C[C@@](O)(CC=2C(O)=C3C(=O)C=4C=CC=C(C=4C(=O)C3=C(O)C=21)OC)C(=O)CO)[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1 AOJJSUZBOXZQNB-TZSSRYMLSA-N 0.000 claims 2
• 238000000034 method Methods 0.000 claims 2
• 238000002560 therapeutic procedure Methods 0.000 claims 2
• 238000011269 treatment regimen Methods 0.000 claims 2
• 229930012538 Paclitaxel Natural products 0.000 claims 1
• VSRXQHXAPYXROS-UHFFFAOYSA-N azanide;cyclobutane-1,1-dicarboxylic acid;platinum(2+) Chemical compound [NH2-].[NH2-].[Pt+2].OC(=O)C1(C(O)=O)CCC1 VSRXQHXAPYXROS-UHFFFAOYSA-N 0.000 claims 1
• 229960000397 bevacizumab Drugs 0.000 claims 1
• 229960004562 carboplatin Drugs 0.000 claims 1
• 229960004679 doxorubicin Drugs 0.000 claims 1
• 229940079593 drug Drugs 0.000 claims 1
• 239000003814 drug Substances 0.000 claims 1
• WOSKHXYHFSIKNG-UHFFFAOYSA-N lenvatinib Chemical compound C=12C=C(C(N)=O)C(OC)=CC2=NC=CC=1OC(C=C1Cl)=CC=C1NC(=O)NC1CC1 WOSKHXYHFSIKNG-UHFFFAOYSA-N 0.000 claims 1
• 229960003784 lenvatinib Drugs 0.000 claims 1
• 229960001592 paclitaxel Drugs 0.000 claims 1
• 229960002621 pembrolizumab Drugs 0.000 claims 1
• 230000000306 recurrent effect Effects 0.000 claims 1
• 150000003839 salts Chemical class 0.000 claims 1
• RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 claims 1
• 229960000575 trastuzumab Drugs 0.000 claims 1